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  1. Article ; Online: Advantages of the co

    Carreira, L Miguel / Azevedo, P

    Lasers in medical science

    2024  Volume 39, Issue 1, Page(s) 114

    Abstract: Nasal mucosa tumors are an uncommon process and very dificult to work on with surgery. Radiotherapy associated or not with chemotherapy is the standard method to treat the disease. However, its access it is in the majority of the case not possible, ... ...

    Abstract Nasal mucosa tumors are an uncommon process and very dificult to work on with surgery. Radiotherapy associated or not with chemotherapy is the standard method to treat the disease. However, its access it is in the majority of the case not possible, making the surgery the best choice to try to achieve the patient's control. The anatomy of the region makes the complete surgical resection very difficult to achieve using the common and conventional blade scalpel surgery. The study features the advantages of using a CO
    MeSH term(s) Dogs ; Animals ; Lasers, Gas/therapeutic use ; Carcinoma, Squamous Cell/surgery ; Carcinoma, Squamous Cell/pathology ; Prospective Studies ; Nasal Mucosa/surgery ; Nasal Mucosa/pathology ; Nose Neoplasms/surgery ; Nose Neoplasms/pathology ; Nose Neoplasms/radiotherapy ; Dog Diseases/surgery ; Male ; Female ; Laser Therapy/methods ; Laser Therapy/instrumentation
    Language English
    Publishing date 2024-04-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 632808-8
    ISSN 1435-604X ; 0268-8921
    ISSN (online) 1435-604X
    ISSN 0268-8921
    DOI 10.1007/s10103-024-04059-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2148: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: The phenomenon of skin contraction in CO

    Nunes, A / Azevedo, P / Carreira, L Miguel

    Lasers in medical science

    2024  Volume 39, Issue 1, Page(s) 117

    Abstract: The skin contraction phenomenon occurs due to the energy emitted by the surgical ... ...

    Abstract The skin contraction phenomenon occurs due to the energy emitted by the surgical CO
    MeSH term(s) Dogs ; Animals ; Lasers, Gas/therapeutic use ; Male ; Female ; Skin/radiation effects ; Skin Physiological Phenomena
    Language English
    Publishing date 2024-04-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 632808-8
    ISSN 1435-604X ; 0268-8921
    ISSN (online) 1435-604X
    ISSN 0268-8921
    DOI 10.1007/s10103-024-04065-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2148: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Sex diferences in serum and synovial fluid C-reactive protein concentration in healthy dogs.

    Carreira, L Miguel / Alves, J / Inacio, F / Pires, G / Azevedo, P

    Veterinary research communications

    2024  

    Abstract: Differences between serum C-reactive protein (SCRP) and synovial fluid C-reactive protein (SFCRP) concentrations in healthy animals may be influenced by the sex of the individual and associated with various factors. The objective of this study was to ... ...

    Abstract Differences between serum C-reactive protein (SCRP) and synovial fluid C-reactive protein (SFCRP) concentrations in healthy animals may be influenced by the sex of the individual and associated with various factors. The objective of this study was to evaluate the disparities in SCRP and SFCRP concentrations between females and males, as well as within each sex. Sixty healthy dogs (N = 60), comprising both sexes, were enrolled in the study. Peripheral blood and knee synovial fluid samples were collected for SCRP and SFCRP analysis, respectively. Serum C-reactive protein (SCRP) and SFCRP concentrations were measured, with mean of 9.61 ± 4.96 mg/L for SCRP and 1.28 ± 3.05 mg/L for SFCRP. Notably, SFCRP concentrations were consistently lower than SCRP concentrations in both sexes. Statistically significant differences were observed between sexes for both SCRP (P = 0.021) and SFCRP (P = 0.007). Further analysis within females revealed statistically significant differences between SCRP and SFCRP concentrations (P = 0.002), whereas in males, such differences were not significant (P = 0.175). Additionally, weak correlations were found between SCRP and SFCRP concentrations for both sexes (females r = 0.07; males r = 0.29). Joint capsule thickness was assessed using ultrasonography, revealing thicker joint capsules in males. A robust positive association was noted between joint capsule thickness and the SFCRP concentration in both sexes. These findings offer valuable insights into the dynamics of CRP in the context of joint health in male and female patients, elucidating the underlying pathological mechanisms of joint disease and inflammation. Overall, this underscores the importance of considering sex-specific factors in the assessment and management of joint health, as well as in the design and interpretation of studies involving SFCRP concentrations.
    Language English
    Publishing date 2024-04-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 406735-6
    ISSN 1573-7446 ; 0165-7380
    ISSN (online) 1573-7446
    ISSN 0165-7380
    DOI 10.1007/s11259-024-10386-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3453: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: The Ways of Saint James in Trás-Os-Montes and Alto Douro as an Example of Soft Tourism in Rural Areas

    Azevedo, Pedro

    European countryside. 2021 June 01, v. 13, no. 2

    2021  

    Abstract: The objective of this study is to demonstrate the importance of the existing Ways of Saint James in Trás-os-Montes and Alto Douro, in the northern interior of Portugal, and that being integrated in soft tourism, can constitute a mechanism that allows the ...

    Abstract The objective of this study is to demonstrate the importance of the existing Ways of Saint James in Trás-os-Montes and Alto Douro, in the northern interior of Portugal, and that being integrated in soft tourism, can constitute a mechanism that allows the revitalization of rural areas, especially the sparsely populated areas, because it allows a series of benefits such as the increase of tourists and pilgrims, the creation of new services, among other structures, thus boosting tourism development. Above all, these Paths linked to soft tourism, allow us to highlight the predominance of tourism linked to nature tourism and slow mobility. In order to carry out this study, the methodology used will be based on interviews to tourists and pilgrims in order to obtain testimonies that can characterise the impact of the Ways themselves on rural territories.
    Keywords Europeans ; area ; ecotourism ; interviews ; objectives ; rural areas ; rural tourism ; tourists ; wills ; Portugal
    Language English
    Dates of publication 2021-0601
    Size p. 314-329.
    Publishing place Sciendo
    Document type Article
    ZDB-ID 2501169-8
    ISSN 1803-8417
    ISSN 1803-8417
    DOI 10.2478/euco-2021-0020
    Database NAL-Catalogue (AGRICOLA)

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  5. Article ; Online: Mepolizumab in severe asthma exacerbation in a respiratory ICU-a successful off-label use.

    Rodrigues, H C / Martins, C / Fragoso, E / Lopes, C / Azevedo, P

    Pulmonology

    2023  Volume 29, Issue 5, Page(s) 438–440

    MeSH term(s) Humans ; Off-Label Use ; Asthma/drug therapy ; Antibodies, Monoclonal, Humanized/therapeutic use ; Intensive Care Units
    Chemical Substances mepolizumab (90Z2UF0E52) ; Antibodies, Monoclonal, Humanized
    Language English
    Publishing date 2023-04-06
    Publishing country Spain
    Document type Letter
    ZDB-ID 3009651-0
    ISSN 2531-0437 ; 2531-0429
    ISSN (online) 2531-0437
    ISSN 2531-0429
    DOI 10.1016/j.pulmoe.2023.03.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The Influence of Noise Level on the Stress Response of Hospitalized Cats.

    Girão, Marisa / Stilwell, George / Azevedo, Pedro / Carreira, L Miguel

    Veterinary sciences

    2024  Volume 11, Issue 4

    Abstract: The study aimed to investigate the impact of noise levels in the hospital environment on the stress experienced by hospitalized cats undergoing elective ovariohysterectomy surgery. A total of 33 domestic female cats were included in the study, divided ... ...

    Abstract The study aimed to investigate the impact of noise levels in the hospital environment on the stress experienced by hospitalized cats undergoing elective ovariohysterectomy surgery. A total of 33 domestic female cats were included in the study, divided into four groups: a control group (CG) and three experimental groups based on ward noise levels: G1 (Quiet, <60 dB), G2 (Medium, between 60 and 85 dB), and G3 (Noisy, >85 dB). Behavioral assessments, respiratory rate (RR), and plasma cortisol levels ([Cort]p) were measured as indicators of stress. A composite measure of stress, termed the final stress value (FSV), was calculated by summing scores across various behavioral categories. Data collection occurred at three time points: immediately following surgery (T1), and at 2 h (T2) and 3 h (T3) post-surgery. FSV and RR were assessed at all three time points (T1, T2, and T3), while [Cort]p levels were measured at T1 and T3. The study observed that the median values of FSV, RR, and [Cort]p tended to increase with both higher noise levels and longer exposure durations to noise. Significant differences in RR were found between group pairs G1G2 at T1 (|D| = 0.63 < cut-off = 0.98), and G2G3 at T2 (|D| = 0.69 < cut-off = 0.97). Regarding [Cort]p, significant differences were noted between the CGG1 group pair at T0 (
    Language English
    Publishing date 2024-04-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2768971-2
    ISSN 2306-7381 ; 2306-7381
    ISSN (online) 2306-7381
    ISSN 2306-7381
    DOI 10.3390/vetsci11040173
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  7. Article ; Online: Functional evaluation of

    Xu, Haoxiang / Gong, Joshua / Lu, Peng / Azevedo, Paula / Li, Linyan / Yu, Hai / Yang, Chengbo

    Translational animal science

    2024  Volume 8, Page(s) txae050

    Abstract: During the bacterial selection, isolate PF9 demonstrated tolerance to low pH and high bile salt and an ability to extend the lifespan ... ...

    Abstract During the bacterial selection, isolate PF9 demonstrated tolerance to low pH and high bile salt and an ability to extend the lifespan of
    Language English
    Publishing date 2024-04-03
    Publishing country England
    Document type Journal Article
    ISSN 2573-2102
    ISSN (online) 2573-2102
    DOI 10.1093/tas/txae050
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  8. Article ; Online: Elexacaftor/tezacaftor/ivacaftor-real-world clinical effectiveness and safety. A single-center Portuguese study.

    Lopes, Kelly / Custódio, Catarina / Lopes, Carlos / Bolas, Raquel / Azevedo, Pilar

    Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia

    2023  Volume 49, Issue 2, Page(s) e20220312

    Abstract: Objective: To evaluate the effectiveness of treatment with elexacaftor/tezacaftor/ivacaftor (ELX/TEZ/IVA) and to characterize its safety profile in cystic fibrosis (CF) patients in a real-world clinical setting.: Methods: This was a prospective ... ...

    Abstract Objective: To evaluate the effectiveness of treatment with elexacaftor/tezacaftor/ivacaftor (ELX/TEZ/IVA) and to characterize its safety profile in cystic fibrosis (CF) patients in a real-world clinical setting.
    Methods: This was a prospective observational study carried out in a CF referral center in Portugal involving adult CF patients who started treatment with ELX/TEZ/IVA. Clinical characteristics of the patients were collected, and effectiveness and safety data were evaluated.
    Results: Of the 56 patients followed in the center at the time of the study, 28 were eligible for ELX/TEZ/IVA treatment in accordance with the Portuguese National Authority for Medicines and Health Products at the time of the study. Of these, 24 met the follow-up time requirement to be included in the clinical effectiveness analysis. The mean follow-up time was 167.3 ± 96.4 days. Adverse events were generally mild and self-limited. Significant improvements in lung function, BMI, sweat chloride concentration, and number of pulmonary exacerbations were observed. No significant differences in outcomes between F508del homozygous and heterozygous patients were found. The effectiveness of this new CFTR modulator combination also applied to patients with advanced lung disease.
    Conclusions: Treatment with ELX/TEZ/IVA showed effective improvement in real-world clinical practice, namely in lung function, BMI, sweat chloride concentration, and number of pulmonary exacerbations, with no safety concerns.
    MeSH term(s) Adult ; Humans ; Cystic Fibrosis Transmembrane Conductance Regulator/genetics ; Portugal ; Chlorides/analysis ; Chlorides/therapeutic use ; Cystic Fibrosis/drug therapy ; Treatment Outcome ; Mutation
    Chemical Substances elexacaftor (RRN67GMB0V) ; Cystic Fibrosis Transmembrane Conductance Regulator (126880-72-6) ; ivacaftor (1Y740ILL1Z) ; tezacaftor ; Chlorides
    Language Portuguese
    Publishing date 2023-02-20
    Publishing country Brazil
    Document type Observational Study ; Journal Article
    ZDB-ID 2223157-2
    ISSN 1806-3756 ; 1806-3713
    ISSN (online) 1806-3756
    ISSN 1806-3713
    DOI 10.36416/1806-3756/e20220312
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: CHEMOTHERAPY HAZARDS: ANTHRACYCLINE EXTRAVASATION INTO PLEURAL SPACE.

    Almendra, Alexandre / Falcão, Pedro / Moreira, Susana / Azevedo, Pilar

    Portuguese journal of cardiac thoracic and vascular surgery

    2022  Volume 29, Issue 1, Page(s) 61–63

    Abstract: The extravasation of doxorubicin, a cytostatic from the anthracycline group, is a rare and feared complication of intravenous chemotherapy due to tissue toxicity of these drugs. We describe a case of a 64-year-old woman with breast cancer undergoing ... ...

    Abstract The extravasation of doxorubicin, a cytostatic from the anthracycline group, is a rare and feared complication of intravenous chemotherapy due to tissue toxicity of these drugs. We describe a case of a 64-year-old woman with breast cancer undergoing adjuvant chemotherapy with doxorubicin and cyclophosphamide using a tunneled central catheter. After a chemotherapy cycle, the patient developed cough, dyspnoea and chest pain, due to a pleural effusion secondary to cytostatic leakage. A pleural drainage was placed and dexrazoxone was administred with resolution of the condition. The authors wish to highlight that the use of dexrazoxone should be considered after intra-pleural extravasation of anthracyclines given its effectiveness in preventing tissue damage and long-term sequelae in peripheral extravasation.
    MeSH term(s) Anthracyclines/adverse effects ; Antibiotics, Antineoplastic/adverse effects ; Cytostatic Agents ; Doxorubicin/adverse effects ; Extravasation of Diagnostic and Therapeutic Materials ; Female ; Humans ; Middle Aged
    Chemical Substances Anthracyclines ; Antibiotics, Antineoplastic ; Cytostatic Agents ; Doxorubicin (80168379AG)
    Language English
    Publishing date 2022-04-11
    Publishing country Portugal
    Document type Case Reports ; Journal Article
    ISSN 2184-9927
    ISSN 2184-9927
    DOI 10.48729/pjctvs.254
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Functional Patients Referred for Deep Brain Stimulation: How Common Is it?

    Gorodetsky, Carolina / Azevedo, Paula / Fasano, Alfonso

    Movement disorders clinical practice

    2022  Volume 9, Issue 6, Page(s) 841–842

    Language English
    Publishing date 2022-06-21
    Publishing country United States
    Document type Journal Article
    ISSN 2330-1619
    ISSN (online) 2330-1619
    DOI 10.1002/mdc3.13495
    Database MEDical Literature Analysis and Retrieval System OnLINE

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