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  1. Book ; Thesis: Erfassung autonom-nervaler und inflammatorischer Veränderungen in der Depression und Schritte zur therapeutischen Einflussnahme durch Sport

    Böttger, Silke

    2016  

    Author's details von Dr. med. Silke Böttger
    Language German ; English
    Size V, 79 Blätter, Illustrationen
    Publishing place Jena
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Habilitationsschrift, Friedrich-Schiller-Universität Jena, 2016
    Note Enthält Sonderabdrucke in englischer Sprache
    HBZ-ID HT019098832
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2016 E 1470 order for loan Magazin

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  2. Book ; Thesis: Dendritische Zellprekursoren im Blut und Dendritische Zellen der Gefäßwand als Ausdruck vaskulärer Inflammation bei Patienten mit koronarer Herzerkrankung (mit und ohne chronische Nierenerkrankung) im Vergleich zu Koronargesunden

    Böttger, Sonja / Busch, Martin / Kretzschmar, Daniel / Schneider, Markus

    2022  

    Abstract: ... 29,5 ... ...

    Institution Friedrich-Schiller-Universität Jena
    Author's details von Sonja Böttger
    Abstract 29,5 cm
    Keywords Dendritische Zelle ; Koronare Herzkrankheit ; Nierenkrankheit
    Subject Nephropathie ; Nierenerkrankung ; Nierenerkrankungen ; Niere ; Renopathie ; Herzkranzgefäßleiden ; Koronararterie ; Herzkranzgefäßkrankheit ; Coronary artery disease
    Language German
    Size VII, 72 Blätter, Illustrationen, Diagramme
    Publishing place Jena
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Friedrich-Schiller-Universität Jena, 2022
    Note Kumulative Dissertation, enthält Zeitschriftenaufsätze. - Tag der Verteidigung: 22.02.22
    HBZ-ID HT021691871
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    2023 E 73 order for loan Magazin

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  3. Article: Dose-dependent QTc interval prolongation under haloperidol and pipamperone in the management of delirium in a naturalistic setting.

    Bohny, Philipp / Boettger, Soenke / Jenewein, Josef

    Frontiers in psychiatry

    2023  Volume 14, Page(s) 1257755

    Abstract: Objective: Delirium is an acute, life-threatening neuropsychiatric disorder frequently occurring among hospitalized patients. Antipsychotic medications are often recommended for delirium management but are associated with cardiovascular risks. This ... ...

    Abstract Objective: Delirium is an acute, life-threatening neuropsychiatric disorder frequently occurring among hospitalized patients. Antipsychotic medications are often recommended for delirium management but are associated with cardiovascular risks. This study aimed to investigate the frequency and magnitude of QTc interval prolongation and clinically relevant side effects occurring in delirium patients managed with haloperidol and/or pipamperone.
    Methods: This descriptive retrospective cohort study evaluated 102 elderly (mean age: 73.2 years) inpatients with delirium treated with either haloperidol, pipamperone, a combination of both, or neither in a naturalistic setting over the course of up to 20 days or until the end of delirium.
    Results: A total of 86.3% of patients were treated with haloperidol and/or pipamperone at a mean daily haloperidol-equipotent dose of 1.2 ± 1 mg. Non-cardiovascular side effects were registered in 2.9% of all patients and correlated with higher scores on the Delirium Observation Screening Scale. They did not occur more frequently under antipsychotic treatment. The frequency of QTc interval prolongation was comparably common among all groups, but prolongation magnitude was higher under antipsychotic treatment. It was positively correlated with antipsychotic dosage and the total number of QTc interval-prolonging substances administered. Critical QTc interval prolongation was registered in 21.6% (
    Conclusion: Delirium treatment with haloperidol and/or pipamperone was not associated with a higher risk of QTc-interval prolongation in this naturalistic patient sample but was greater in magnitude and correlated with equipotent dosage and the number of QT interval-prolonging substances used. Polypharmacy was associated with higher mortality and increased risk of critical QTc prolongation.
    Language English
    Publishing date 2023-10-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2023.1257755
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: [Delirium Update: Risk Factors, Management, and Biomarkers].

    Zipser, Carl M / von Känel, Roland / Boettger, Soenke

    Praxis

    2023  Volume 112, Issue 12, Page(s) 599–604

    Abstract: Introduction: A delirium can be encountered in almost all hospital sectors. The prevalence varies between 20 and 40 % in internal medicine and surgical wards and between 50 and 60 % in palliative care and intensive care units. A delirium is ... ...

    Abstract Introduction: A delirium can be encountered in almost all hospital sectors. The prevalence varies between 20 and 40 % in internal medicine and surgical wards and between 50 and 60 % in palliative care and intensive care units. A delirium is characterized by impaired attention, consciousness, and cognitive impairment with acute onset and fluctuating course. People with delirium have inferior clinical outcomes, including higher mortality and more need for long-term care after discharge. This article first reviews the clinical and pathophysiologic basis of delirium, followed by a detailed description of individual risk profiles based on a prospective, hospital-wide cohort study (Delir-Path) conducted at the University Hospital Zurich. We will then give a brief update on diagnosis and management of delirium and an outlook on how neurophysiology and blood biomarkers can complement delirium care in the future.
    MeSH term(s) Humans ; Delirium/diagnosis ; Delirium/epidemiology ; Delirium/etiology ; Cohort Studies ; Prospective Studies ; Intensive Care Units ; Risk Factors
    Language German
    Publishing date 2023-11-16
    Publishing country Switzerland
    Document type English Abstract ; Journal Article ; Review
    ZDB-ID 209026-0
    ISSN 1661-8165 ; 1661-8157 ; 0369-8394
    ISSN (online) 1661-8165
    ISSN 1661-8157 ; 0369-8394
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.118: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 12: Show issues

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  5. Book ; Online: Nachhaltigkeitsbewertung von Kleinkläranlagen mittels Ökoeffizienzanalyse zur Ableitung von Produktverbesserungen

    Böttger, Stefan / Laforet, Lydie / Holländer, Robert / Töws, Ingo / Lautenschläger, Sabine / Schimpke, Jacqueline / Lange, Antje / Stich, Gabriele

    2016  

    Keywords Business & management ; Business & Economics
    Language German
    Size 1 Online-Ressource
    Publisher Logos Verlag Berlin
    Document type Book ; Online
    Note German
    HBZ-ID HT030721490
    ISBN 9783832543686 ; 3832543686
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  6. Article ; Online: Delirium in supportive and palliative care.

    Boettger, Soenke / Breitbart, William

    Palliative & supportive care

    2021  Volume 19, Issue 3, Page(s) 267

    MeSH term(s) Delirium ; Hospice and Palliative Care Nursing ; Humans ; Palliative Care
    Language English
    Publishing date 2021-07-08
    Publishing country England
    Document type Editorial
    ZDB-ID 2454009-2
    ISSN 1478-9523 ; 1478-9515
    ISSN (online) 1478-9523
    ISSN 1478-9515
    DOI 10.1017/S1478951521000638
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6697: Show issues Location:
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  7. Book ; Online: Hybrid Learning of Time-Series Inverse Dynamics Models for Locally Isotropic Robot Motion

    Çallar, Tolga-Can / Böttger, Sven

    2022  

    Abstract: Applications of force control and motion planning often rely on an inverse dynamics model to represent the high-dimensional dynamic behavior of robots during motion. The widespread occurrence of low-velocity, small-scale, locally isotropic motion (LIMO) ... ...

    Abstract Applications of force control and motion planning often rely on an inverse dynamics model to represent the high-dimensional dynamic behavior of robots during motion. The widespread occurrence of low-velocity, small-scale, locally isotropic motion (LIMO) typically complicates the identification of appropriate models due to the exaggeration of dynamic effects and sensory perturbation caused by complex friction and phenomena of hysteresis, e.g., pertaining to joint elasticity. We propose a hybrid model learning base architecture combining a rigid body dynamics model identified by parametric regression and time-series neural network architectures based on multilayer-perceptron, LSTM, and Transformer topologies. Further, we introduce novel joint-wise rotational history encoding, reinforcing temporal information to effectively model dynamic hysteresis. The models are evaluated on a KUKA iiwa 14 during algorithmically generated locally isotropic movements. Together with the rotational encoding, the proposed architectures outperform state-of-the-art baselines by a magnitude of 10$^3$ yielding an RMSE of 0.14 Nm. Leveraging the hybrid structure and time-series encoding capabilities, our approach allows for accurate torque estimation, indicating its applicability in critically force-sensitive applications during motion sequences exceeding the capacity of conventional inverse dynamics models while retaining trainability in face of scarce data and explainability due to the employed physics model prior.

    Comment: Accepted for publication in IEEE Robotics and Automation Letters ( see https://ieeexplore.ieee.org/document/9954138 ). 8 pages, 8 figures
    Keywords Computer Science - Robotics ; Electrical Engineering and Systems Science - Systems and Control
    Subject code 629
    Publishing date 2022-11-23
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Tormentillae rhizoma - Review for an Underestimated European Herbal Drug.

    Melzig, Matthias F / Böttger, Stefan

    Planta medica

    2020  Volume 86, Issue 15, Page(s) 1050–1057

    Abstract: Potentilla ... ...

    Abstract Potentilla erecta
    MeSH term(s) Europe ; Herbal Medicine ; Phytotherapy ; Plants, Medicinal ; Rhizome
    Language English
    Publishing date 2020-03-10
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 123545-x
    ISSN 1439-0221 ; 0032-0943
    ISSN (online) 1439-0221
    ISSN 0032-0943
    DOI 10.1055/a-1129-7214
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uf I Zs.157: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  9. Book: Dolobene Gel und Strom

    Böttger, Sabine

    zwei Prinzipien im Einklang ; Synergie für erfolgreiche Therapie

    (Fortschritte der Medizin : Monographie ; 44)

    1991  

    Author's details Sabine Böttger
    Series title Fortschritte der Medizin : Monographie ; 44
    Fortschritte der Medizin
    Fortschritte der Medizin ; Monographie
    Collection Fortschritte der Medizin
    Fortschritte der Medizin ; Monographie
    Keywords Dimethyl Sulfoxide / therapeutic use ; Iontophoresis ; Combined Modality Therapy ; Rheumatic Diseases / therapy ; Athletic Injuries / therapy ; Iontophorese ; Panthenol
    Subject Dolobene Gel ; Dolobene-Gel
    Size 15 S. : Ill., graph. Darst.
    Edition 2., unveränd. Aufl.
    Publisher Urban & Vogel
    Publishing place München
    Document type Book
    HBZ-ID HT004010899
    ISBN 3-923318-75-8 ; 978-3-923318-75-9
    Database Catalogue ZB MED Medicine, Health

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    Ua VI Zs 85 -Monogr.44- verfügbar in Königswinter Königswinter

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  10. Article ; Online: QTc prolongation after haloperidol administration in critically ill patients post cardiovascular surgery: A cohort study and review of the literature - CORRIGENDUM.

    Ibrahimi, Burbuqe / Boettger, Soenke / Schubert, Maria / Bettex, Dominique / Rudiger, Alain

    Palliative & supportive care

    2022  Volume 20, Issue 1, Page(s) 149

    Language English
    Publishing date 2022-02-09
    Publishing country England
    Document type Journal Article ; Published Erratum
    ZDB-ID 2454009-2
    ISSN 1478-9523 ; 1478-9515
    ISSN (online) 1478-9523
    ISSN 1478-9515
    DOI 10.1017/S1478951521000559
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6697: Show issues Location:
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