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Book ; Thesis: Hemodynamics of the juvenile knee

Bünger, Cody

joint effusion and synovial inflammation studied in dogs

(Acta orthopaedica Scandinavica : Supplementum ; 222)

1987

Series title	Acta orthopaedica Scandinavica : Supplementum ; 222 Acta orthopaedica Scandinavica Acta orthopaedica Scandinavica ; Supplementum
Collection	Acta orthopaedica Scandinavica Acta orthopaedica Scandinavica ; Supplementum
Keywords	Knee Joint / physiology ; Knee Joint / physiopathology ; Hemodynamics ; Hämodynamik ; Kniegelenk ; Hund ; Entzündung
Subject	Canis familiaris ; Canis lupus familiaris ; Haushund ; Dog ; Inflammatio ; Entzündungsreaktion ; Knie ; Articulatio genus ; Kniegelenke
Size	104 S.: Ill., graph. Darst.
Publisher	Munksgaard
Publishing place	Copenhagen
Publishing country	Denmark
Document type	Book ; Thesis
Thesis / German Habilitation thesis	Aarhus, Univ., Diss
HBZ-ID	HT002989644
ISBN	87-16-06376-7 ; 978-87-16-06376-2
Database	Catalogue ZB MED Medicine, Health

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Uk I Zs 99 -Suppl.222-	verfügbar in Königswinter	Königswinter

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Article ; Online: A multi-scale keypoint estimation network with self-supervision for spinal curvature assessment of idiopathic scoliosis from the imperfect dataset.

Liu, Tianyu / Wang, Yu / Yang, Yukang / Sun, Ming / Fan, Wenhui / Bunger, Cody / Wu, Cheng

Artificial intelligence in medicine

2022 Volume 125, Page(s) 102235

Abstract: Idiopathic scoliosis (IS) is a common lifetime disease, which exhibits an obvious deformity of spinal curvature to seriously affect heart and lung function. Accurate radiographic assessment of spinal curvature is vitally important for the clinical ... ...

Abstract	Idiopathic scoliosis (IS) is a common lifetime disease, which exhibits an obvious deformity of spinal curvature to seriously affect heart and lung function. Accurate radiographic assessment of spinal curvature is vitally important for the clinical diagnosis and treatment planning of idiopathic scoliosis. Deep learning algorithms have been widely adopted to the medical image analysis with the remarkable advancement in computer vision. The automated methods can improve the efficiency of clinical diagnosis to relieve the burden of doctors, which have advantage in dealing with the tedious and repetitive tasks. However, existing methods usually require sufficiently large training datasets with strict annotation, which are costly and laborious especially for medical images. Moreover, the medical images of serious IS always contain the blurry and occlusive parts, which would make the accurate and robust estimation of the spinal curvature more difficult. In this paper, a dot annotation approach is presented to train the spinal curvature assessment model, rather than using strict annotation of IS X-ray images. We develop a multi-scale keypoint estimation network to reduce the requirement for large training datasets, in which the Squeeze-and-Excitation (SE) blocks are incorporated to improve the representational capacity of the model. Then, a self-supervision module is designed to alleviate the blurry and occlusive problem, and we use the two-view radiographic assessments of IS to generate a 3D spinal curvature. Finally, extensive experiments are conducted on a collected clinical dataset, in which we obtain 81.5 AP and the average E
MeSH term(s)	Algorithms ; Humans ; Scoliosis/diagnostic imaging ; Spinal Curvatures
Language	English
Publishing date	2022-01-20
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	645179-2
ISSN	1873-2860 ; 0933-3657
ISSN (online)	1873-2860
ISSN	0933-3657
DOI	10.1016/j.artmed.2021.102235
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Zs.A 2547: Show issues

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Article ; Online: Does transforaminal lumbar interbody fusion produce leg pain?-Results from a RCT.

Høy, Kristian / Grycel, Blazej / Andersen, Thomas / Bünger, Cody

Journal of orthopaedic surgery (Hong Kong)

2019 Volume 27, Issue 3, Page(s) 2309499019869469

Abstract: Background: Transforaminal lumbar interbody fusion (TLIF) is presently the most used method to achieve lumbar interbody fusion worldwide. The special preparation and cage insertion imply a risk of an undesirable side effect in the form of residual ... ...

Abstract	Background: Transforaminal lumbar interbody fusion (TLIF) is presently the most used method to achieve lumbar interbody fusion worldwide. The special preparation and cage insertion imply a risk of an undesirable side effect in the form of residual neurogenic pain. This issue has not been investigated prior in a randomized clinical trial (RCT) set up. Aim: To test whether TLIFs had a higher incidence of leg pain in comparison to a common instrumented posterolateral fusion (PLF) and to test whether a higher occurrence of leg pain on the ipsilateral side in the TLIF group was present. Methods: One hundred patients included in a RCT comparing TLIF and PLF fulfilled pain drawings and numeric rating scale (NRS) scale from 0 to 10 preoperatively, after 1 year, and after 2 years. Difference in pain appearance, type, localization, and intensity was compared between groups. Results: A slightly higher number of patients in the TLIF group reported leg pain at 2 years follow-up: no leg pain, 47% (PLF) and 37% (TLIF); unilateral leg pain, 31% (PLF) and 25% (TLIF); bilateral leg pain, 22% (PLF) and 37% (TLIF), Conclusion: The special surgical preparation used in TLIFs does not result in the development of new ipsilateral leg pain. However, a higher percentage of the patients in the TLIF group had new leg pain in comparison to PLF after 2 years.
MeSH term(s)	Adult ; Aged ; Female ; Humans ; Internal Fixators ; Leg ; Lumbar Vertebrae ; Male ; Middle Aged ; Pain, Postoperative/epidemiology ; Spinal Fusion/adverse effects ; Spinal Fusion/methods ; Treatment Outcome
Language	English
Publishing date	2019-08-06
Publishing country	England
Document type	Journal Article ; Randomized Controlled Trial
ZDB-ID	1493368-8
ISSN	2309-4990 ; 1022-5536
ISSN (online)	2309-4990
ISSN	1022-5536
DOI	10.1177/2309499019869469
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Zs.A 5104: Show issues

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Book: Die offene Frage der Mündigkeit

Bünger, Carsten

Studien zur Politizität der Bildung

(Theorieforum Pädagogik ; 5)

2013

Author's details	Carsten Bünger
Series title	Theorieforum Pädagogik ; 5
Keywords	Education/Political aspects/Philosophy ; Politik ; Bildungsgang ; Individualität ; Bildungsforschung ; Gesellschaft
Language	German
Size	247 S.
Publisher	Schöningh
Publishing place	Paderborn u.a.
Document type	Book
Note	Literaturverz. S. [235] - 247
ISBN	3506777998 ; 9783506777997
Database	Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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Conference proceedings: Interventional Applicability of Biodegradable Polymeric Stents in a Por-cine Model

Bünger, Carsten

2012 , Page(s) 12dgch570

Event/congress	129. Kongress der Deutschen Gesellschaft für Chirurgie; Berlin; Deutsche Gesellschaft für Chirurgie; 2012
Keywords	Medizin, Gesundheit
Publishing date	2012-04-23
Publisher	German Medical Science GMS Publishing House; Düsseldorf
Document type	Conference proceedings
DOI	10.3205/12dgch570
Database	German Medical Science

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Article ; Online: Nephrotisches Syndrom und Mikrohämaturie bei einer Patientin mit Nussknacker-Syndrom: Ein Fallbericht mit Literaturübersicht.

Schöffel, N / Liehr, R-M / Bünger, C / Krüger, K / Rubin, D

Der Internist

2017 Volume 59, Issue 6, Page(s) 608–614

Abstract: We report about a 43-year-old woman with polyvalent drug addiction (i.e. alcohol, nicotine, methadone maintenance program with parallel consumption of heroin) who presented to the emergency department with peripheral edema, generalized weakness, and ... ...

Title translation	Nephrotic syndrome and microhematuria in a patient with nutcracker syndrome: Report of a case and review of the literature.
Abstract	We report about a 43-year-old woman with polyvalent drug addiction (i.e. alcohol, nicotine, methadone maintenance program with parallel consumption of heroin) who presented to the emergency department with peripheral edema, generalized weakness, and arthralgia. Laboratory findings revealed, among others, proteinuria, hyperlipoproteinemia and hypoproteinemia defining nephrotic syndrome. Computed tomography of the abdomen and iliocavography further revealed compression of left renal vein between aorta and superior mesenteric artery with distention of left ovarian vein as a possible cause of nephrotic syndrome (i. e. nutcracker syndrome). After excluding other possible causes of nephrotic syndrome, we decided against an interventional procedure due to poor compliance of the patient and potential risk of secondary stent dislocation. Instead, we opted for a surgical approach (i. e. veno-venous bypass, meaning transposition of left vena ovarica on vena cava inferior). The operative and postoperative course was uneventful. Postoperatively, proteinuria, microhematuria, arthralgia and edema receded.
MeSH term(s)	Adult ; Female ; Hematuria/complications ; Humans ; Mesenteric Artery, Superior ; Nephrotic Syndrome/complications ; Renal Nutcracker Syndrome/complications ; Renal Veins ; Syndrome ; Vena Cava, Inferior
Language	German
Publishing date	2017-11-27
Publishing country	Germany
Document type	Case Reports ; Journal Article ; Review
ZDB-ID	2913-0
ISSN	1432-1289 ; 0020-9554
ISSN (online)	1432-1289
ISSN	0020-9554
DOI	10.1007/s00108-017-0350-9
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Ua VI Zs.380: Show issues

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Article: Temporary axial rotation stabilization for lumbar disc herniation surgery with the ARO

Rickers, Kresten Wendell / Li, Haisheng / Robie, Bruce / Bünger, Cody

Journal of spine surgery (Hong Kong)

2019 Volume 5, Issue 1, Page(s) 124–131

Abstract: Background: Decompressive surgery has a failure rate of between 25% and 32% based on patient reported improvement in clinical symptoms. Significant back pain is associated with 53% of failures of decompressive surgery, while also being associated with ... ...

Abstract	Background: Decompressive surgery has a failure rate of between 25% and 32% based on patient reported improvement in clinical symptoms. Significant back pain is associated with 53% of failures of decompressive surgery, while also being associated with abnormal axial rotation motion. We report on the clinical performance of subjects receiving a novel axial rotation stabilization implant (ARO Spinal System, ARO Medical), while undergoing a surgical decompression for a herniated lumbar disc, a condition associated with low back pain and abnormal movement. Methods: This Danish Medicines Agency and Ethics Committee approved clinical trial prospectively investigated the use of the ARO Results: No complications with the implant were observed. Four serious adverse events not related to the devices were reported, one subject had reoperation at 3 months. Leg pain median VAS score decreased from 70 to 2 at 1 year (P=0.01) back pain median VAS score from 48 to 6 (P=0.04). Satisfaction with surgery was 88%. Oswestry Disability Index scored likewise improvement going from 38 pre-operative to 5 at 1 year. Follow-up rate was excellent 100%. Conclusions: Discectomy with the ARO Spinal System proves equally safe as a standard discectomy at 1 year follow-up. The subjects had significant improvements in both leg and back pain. In addition, they did better than historical controls, though not statistically so in this patient sample.
Language	English
Publishing date	2019-04-08
Publishing country	China
Document type	Journal Article
ZDB-ID	2874556-5
ISSN	2414-4630 ; 2414-469X
ISSN (online)	2414-4630
ISSN	2414-469X
DOI	10.21037/jss.2018.12.13
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Article ; Online: Lengthening of magnetically controlled growing rods caused minimal pain in 25 children: pain assessment with FPS-R, NRS, and r-FLACC.

Skov, Simon Toftgaard / Bünger, Cody / Li, Haisheng / Vigh-Larsen, Marianne / Rölfing, Jan Duedal

Spine deformity

2020 Volume 8, Issue 4, Page(s) 763–770

Abstract: Study design: Descriptive case series.: Objective: The aim of the study is to investigate the pain associated with magnetically controlled growing rod (MCGR) lengthening procedures. MCGRs have gained popularity because they offer non-surgical ... ...

Abstract	Study design: Descriptive case series. Objective: The aim of the study is to investigate the pain associated with magnetically controlled growing rod (MCGR) lengthening procedures. MCGRs have gained popularity because they offer non-surgical lengthening procedures in early-onset scoliosis (EOS) instead of semi-annual open surgery elongations with traditional growing rods. Many aspects of MCGR treatment have been investigated, but pain in conjunction with distraction is only sparsely described in the literature. Methods: Pain intensity was assessed in 25 EOS patients before, during and after MCGR lengthening procedures in an outpatient setup. They underwent at least two (range 2-16) lengthening procedures prior to this study. The pain intensity was estimated using patient-reported Faces Pain Scale (FPS-R), caregiver-reported pain numeric rating scale (NRS), and NRS and revised Face, Legs, Activity, Cry, Consolability scale (r-FLACC) by two medically trained observers. The inter-rater reliability and correlation between instruments were analyzed. Results: 23 of 25 EOS patients (8- to 16-year old) with mixed etiology were able to self-report pain. The average pain intensity was mild: median 1 (range 0-6) on all four instruments on a 0-to-10 scale. Afterward, 22/25 patients (88%) were completely pain free and the remaining 3 patients had a pain score of 1. MCGR stalling (i.e. clunking) was encountered in 14/25 (56%) of the patients without impact on the pain intensity. Conclusions: The average maximum pain intensities during the lengthening procedures were mild and pain ceased within few minutes. The inter-rater reliability was good to excellent for NRS and r-FLACC, and there were high correlations between all the four pain instruments, indicating high criterion validity. Level of evidence: Level IV, case series.
MeSH term(s)	Adolescent ; Age of Onset ; Child ; Child, Preschool ; Face/physiology ; Female ; Humans ; Internal Fixators/adverse effects ; Male ; Osteogenesis, Distraction/adverse effects ; Osteogenesis, Distraction/methods ; Pain/etiology ; Pain/prevention & control ; Pain Measurement/methods ; Scoliosis/surgery
Language	English
Publishing date	2020-03-13
Publishing country	England
Document type	Journal Article
ZDB-ID	2717704-X
ISSN	2212-1358 ; 2212-134X ; 2212-1358
ISSN (online)	2212-1358 ; 2212-134X
ISSN	2212-1358
DOI	10.1007/s43390-020-00096-3
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Article: Symptomatic lumbosacral transitional vertebra: a review of the current literature and clinical outcomes following steroid injection or surgical intervention.

Holm, Emil Kongsted / Bünger, Cody / Foldager, Casper Bindzus

SICOT-J

2017 Volume 3, Page(s) 71

Abstract: Bertolotti's syndrome (BS) refers to the possible association between the congenital malformation lumbosacral transitional vertebra (LSTV), and low back pain (LBP). Several treatments have been proposed including steroid injections, resections of the ... ...

Abstract	Bertolotti's syndrome (BS) refers to the possible association between the congenital malformation lumbosacral transitional vertebra (LSTV), and low back pain (LBP). Several treatments have been proposed including steroid injections, resections of the LSTV, laminectomy, and lumbar spinal fusion. The aim of this review was to compare the clinical outcomes in previous trials and case reports for these treatments in patients with LBP and LSTV. A PubMed search was conducted. We included English studies of patients diagnosed with LSTV treated with steroid injection, laminectomy, spinal fusion or resection of the transitional articulation. Of 272 articles reviewed 20 articles met the inclusion criteria. Their level of evidence were graded I-V and the clinical outcomes were evaluated. Only 1 study had high evidence level (II). The remainders were case series (level IV). Only 5 studies used validated clinical outcome measures. A total of 79 patients were reported: 31 received treatment with steroid injections, 33 were treated with surgical resection of the LSTV, 8 received lumbar spinal fusion, and 7 cases were treated with laminectomy. Surgical management seems to improve the patient's symptoms, especially patients diagnosed with "far out syndrome" treated with laminectomy. Clinical outcomes were more heterogenetic for patient's treated with steroid injections. The literature regarding BS is sparse and generally with low evidence. Non-surgical management (e.g., steroid injections) and surgical intervention could not directly be compared due to lack of standardization in clinical outcome. Generally, surgical management seems to improve patient's clinical outcome over time, whereas steroid injection only improves the patient's symptoms temporarily. Further studies with larger sample size and higher evidence are warranted for the clinical guidance in the treatment of BS.
Language	English
Publishing date	2017-12-12
Publishing country	France
Document type	Journal Article
ISSN	2426-8887
ISSN	2426-8887
DOI	10.1051/sicotj/2017055
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Article ; Online: Addition of TLIF does not improve outcome over standard posterior instrumented fusion. 5-10 years long-term Follow-up: results from a RCT.

Høy, Kristian / Truong, Kamilla / Andersen, Thomas / Bünger, Cody

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

2017 Volume 26, Issue 3, Page(s) 658–665

Abstract: Purpose: The use of inter-body device in lumbar fusions has been difficult to validate, only few long-term RCT are available.: Methods: Between 2003 and 2005, 100 patients entered a RCT between transforaminal lumbar inter-body fusion (TLIF) or ... ...

Abstract	Purpose: The use of inter-body device in lumbar fusions has been difficult to validate, only few long-term RCT are available. Methods: Between 2003 and 2005, 100 patients entered a RCT between transforaminal lumbar inter-body fusion (TLIF) or posterolateral instrumented lumbar fusion (PLF). The patients suffered from LBP due to segmental instability, disc degeneration, former disc herniation, spondylolisthesis Meyerding grade <2. Functional outcome parameters as Dallas pain questionnaire (DPQ), SF-36, low back pain questionnaire (LBRS), Oswestry disability index (ODI) were registered prospectively, and after 5-10 years. Results: Follow-up reached 93 % of available, (94 %, 44 in the PLF's and 92 %, 44 in the TLIF group p = 0.76). Mean follow-up was 8.6 years (5-10 years). Mean age at follow-up was 59 years (34-76 years p = 0.19). Reoperation rate in a long-term perspective was equal among groups 14 %, each p = 0.24. Back pain was 3.8 (mean) (Scale 0-10), TLIF (3.65) PLF (3.97) p = 0.62, leg pain 2.68 (mean) (Scale 0-10) 2.90 (TLIF) and 2.48 (PLF) p = 0.34. No difference in functional outcome between groups p = 0.93. Overall, global satisfaction with the primary intervention at 8.6 year was 76 % (75 % TLIF and 77 % PLF) p = 0.85. Conclusion: In a long-term perspective, patients with TLIF's did not experience better outcome scores.
Language	English
Publishing date	2017-03
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1115375-1
ISSN	1432-0932 ; 0940-6719
ISSN (online)	1432-0932
ISSN	0940-6719
DOI	10.1007/s00586-016-4592-3
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