Article: The relation between uric acid level and blood pressure values among patients hospitalized in a department of internal medicine.
Postepy w kardiologii interwencyjnej = Advances in interventional cardiology
2023 Volume 19, Issue 2, Page(s) 142–151
Abstract: Introduction: The relationship between uric acid (UA) level and blood pressure (BP) is not clear, although most studies suggest BP reduction in patients treated with UA level lowering agents.: Aim: The aim of the study was to evaluate the ... ...
| Abstract | Introduction: The relationship between uric acid (UA) level and blood pressure (BP) is not clear, although most studies suggest BP reduction in patients treated with UA level lowering agents. Aim: The aim of the study was to evaluate the relationship between UA level and BP among patients hospitalized in a department of internal medicine. We also intended to investigate the relation between the allopurinol dose prescribed and BP. Material and methods: We reviewed hospital records of 561 patients (mean age: 65.46 ±17.46 years) hospitalized in a department of internal medicine, in whom UA level was determined on admission. Results: We did not find a significant correlation between UA level and BP values in the whole group, nor in patients not taking any BP-lowering or any UA-lowering drug. Multivariable analysis showed that allopurinol dose was not independently related to BP. Age (OR = 1.04, 95% CI: 1.03-1.06 per 1 year), diabetes (OR = 1.90, 95% CI: 1.14-3.16), stage 2 (OR = 4.96, 95% CI: 2.15-11.46) and stage 3 obesity (OR = 13.66, 95% CI: 5.90-31.60), both vs. patients without stage 2/3 obesity, but not UA level, were independently related to the diagnosis of hypertension. Conclusions: Our study does not confirm an independent relationship between UA level and BP nor between UA lowering and BP in a population of hospitalized patients. |
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| Language | English |
| Publishing date | 2023-06-30 |
| Publishing country | Poland |
| Document type | Journal Article |
| ISSN | 1734-9338 |
| ISSN | 1734-9338 |
| DOI | 10.5114/aic.2023.129213 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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