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  1. Article ; Online: Thalassemia in Viet Nam.

    Bach, Khanh Q / Nguyen, Ha T T / Nguyen, Thanh H / Nguyen, Minh B / Nguyen, Tri A

    Hemoglobin

    2022  Volume 46, Issue 1, Page(s) 62–65

    Abstract: The population of Viet Nam, is 96.2 million, of which 13.8% are carriers of thalassemia genes. Thalassemia/hemoglobinopathies carriers exist at different frequencies in all 54 ethnic groups of the country. Gene carrier rate and globin gene mutation rate ... ...

    Abstract The population of Viet Nam, is 96.2 million, of which 13.8% are carriers of thalassemia genes. Thalassemia/hemoglobinopathies carriers exist at different frequencies in all 54 ethnic groups of the country. Gene carrier rate and globin gene mutation rate varies ethnically and topographically. The ethnic groups in the Northern Highland region have high rates of α
    MeSH term(s) Female ; Genotype ; Hemoglobinopathies/genetics ; Heterozygote ; Humans ; Infant, Newborn ; Mutation ; Pregnancy ; Vietnam/epidemiology ; alpha-Thalassemia/diagnosis ; alpha-Thalassemia/epidemiology ; alpha-Thalassemia/genetics ; beta-Thalassemia/diagnosis ; beta-Thalassemia/epidemiology ; beta-Thalassemia/genetics
    Language English
    Publishing date 2022-06-23
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 750615-6
    ISSN 1532-432X ; 0363-0269
    ISSN (online) 1532-432X
    ISSN 0363-0269
    DOI 10.1080/03630269.2022.2069032
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1345: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Pre-chemotherapy white blood cell depletion by therapeutic leukocytapheresis in leukemia patients: A single-institution experience.

    Nguyen, Thanh H / Bach, Khanh Q / Vu, Hung Q / Nguyen, Nhat Q / Duong, Thien D / De Reys, Stef / Wheeler, Jennifer

    Journal of clinical apheresis

    2019  Volume 35, Issue 2, Page(s) 117–124

    Abstract: Background: Hyperleukocytosis is commonly seen in acute and chronic leukemias. Therapeutic leukocytapheresis using an automatic cell separator can help to achieve prompt leukoreduction to reduce the rate of thrombotic events and early mortality as well ... ...

    Abstract Background: Hyperleukocytosis is commonly seen in acute and chronic leukemias. Therapeutic leukocytapheresis using an automatic cell separator can help to achieve prompt leukoreduction to reduce the rate of thrombotic events and early mortality as well as to prevent tumor lysis syndrome.
    Aim: In this study, we report a single center's experience in managing leukemia patients with therapeutic leukocytapheresis prior to chemotherapy.
    Materials and methods: Leukocytapheresis procedures were performed in 192 leukemia patients (including acute myeloid leukemia [AML], acute lymphoblastic leukemia [ALL], and chronic myeloid leukemia [CML]) with hyperleukocytosis between January and December 2016.
    Results: Median % reduction of white blood cell (WBC) count was 30.5% and median % removal efficiency was 46.7% for 75 procedures where the waste bag was sampled. WBC removal efficiency strongly depended on diagnosis (and was 71%, 66%, and 39% for ALL, AML, and CML, respectively). Procedures were generally well tolerated with only 9 out of 192 patients having mild adverse effects.
    Discussion and conclusion: In the absence of specific guidelines for the management of hyperleukocytosis, leukocytapheresis in association with chemotherapy should be considered early in clinical practice.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Antineoplastic Agents/pharmacology ; Child ; Combined Modality Therapy ; Drug Therapy/methods ; Female ; Humans ; Leukapheresis/methods ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/therapy ; Leukemia, Myeloid, Acute/therapy ; Leukocyte Count ; Leukocytes/cytology ; Leukocytosis/physiopathology ; Leukocytosis/therapy ; Male ; Middle Aged ; Platelet Count ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/therapy ; Tumor Lysis Syndrome/therapy ; Young Adult
    Chemical Substances Antineoplastic Agents
    Language English
    Publishing date 2019-12-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604912-6
    ISSN 1098-1101 ; 0733-2459
    ISSN (online) 1098-1101
    ISSN 0733-2459
    DOI 10.1002/jca.21766
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1831: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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