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Article ; Online: Intracoronary administration of autologous mesenchymal stem cells in a critically ill patient with dilated cardiomyopathy.

Zeinaloo, Aliakbar / Zanjani, Keyhan S / Bagheri, Mohammad M / Mohyeddin-Bonab, Mandana / Monajemzadeh, Maryam / Arjmandnia, Mohammad H

Pediatric transplantation

2011  Volume 15, Issue 8, Page(s) E183–6

Abstract: Relatively high prevalence of dilated cardiomyopathy in children, unfavorable response to traditional drug therapy, and limitations in heart transplantation call for new therapeutic options. Stem cell therapy can be promising in children suffering from ... ...

Abstract Relatively high prevalence of dilated cardiomyopathy in children, unfavorable response to traditional drug therapy, and limitations in heart transplantation call for new therapeutic options. Stem cell therapy can be promising in children suffering from this disease. The presented case documents that intracoronary injection of autologous bone marrow-derived mesenchymal stem cells in a boy with progressive dilated cardiomyopathy is feasible and safe. Furthermore, it may positively influence functional class, quality of life, and echocardiographic indices of cardiac function.
MeSH term(s) Cardiomyopathy, Dilated/diagnostic imaging ; Cardiomyopathy, Dilated/pathology ; Cardiomyopathy, Dilated/therapy ; Child ; Coronary Vessels ; Echocardiography ; Humans ; Injections, Intra-Arterial ; Male ; Mesenchymal Stem Cell Transplantation/methods ; Myocardium/pathology
Language English
Publishing date 2011-12
Publishing country Denmark
Document type Case Reports ; Journal Article
ZDB-ID 1390284-2
ISSN 1399-3046 ; 1397-3142
ISSN (online) 1399-3046
ISSN 1397-3142
DOI 10.1111/j.1399-3046.2010.01366.x
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