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  1. Article ; Online: Methylprednisolone or Intravenous Immunoglobulin in Children with Paediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2 (PIMS-TS)?: Pediatric Rheumatologist's Viewpoint.

    Bagri, Narendra Kumar

    Indian pediatrics

    2023  Volume 60, Issue 7, Page(s) 574–575

    MeSH term(s) Child ; Humans ; COVID-19 ; SARS-CoV-2 ; Immunoglobulins, Intravenous/therapeutic use ; Methylprednisolone/therapeutic use ; Rheumatologists
    Chemical Substances Immunoglobulins, Intravenous ; Methylprednisolone (X4W7ZR7023)
    Language English
    Publishing date 2023-07-09
    Publishing country India
    Document type Journal Article ; Comment
    ZDB-ID 402594-5
    ISSN 0974-7559 ; 0019-6061
    ISSN (online) 0974-7559
    ISSN 0019-6061
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 859: Show issues Location:
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  2. Article ; Online: The Enigma of Pediatric Multisystem Inflammatory Syndrome Temporally Associated with SARS-CoV-2 (PMIS-TS).

    Bagri, Narendra Kumar

    Indian journal of pediatrics

    2022  Volume 89, Issue 9, Page(s) 855–856

    MeSH term(s) COVID-19/complications ; Child ; Humans ; Intensive Care Units, Pediatric ; SARS-CoV-2 ; Systemic Inflammatory Response Syndrome/complications ; Systemic Inflammatory Response Syndrome/diagnosis
    Language English
    Publishing date 2022-07-13
    Publishing country India
    Document type Editorial ; Comment
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-022-04302-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 826: Show issues Location:
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  3. Article ; Online: Autoantibodies in Juvenile Dermatomyositis: Need to Bridge the Bench and Bedside Gap.

    Bagri, Narendra Kumar

    Indian journal of pediatrics

    2021  Volume 88, Issue 12, Page(s) 1167–1168

    MeSH term(s) Autoantibodies ; Dermatomyositis/diagnosis ; Humans
    Chemical Substances Autoantibodies
    Language English
    Publishing date 2021-10-05
    Publishing country India
    Document type Editorial ; Comment
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-021-03971-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 826: Show issues Location:
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  4. Article ; Online: Secukinumab for children and adolescents with enthesitis-related arthritis and psoriatic arthritis:

    Bagri, Narendra Kumar / King, Hayley / Ramanan, A V

    Expert review of clinical immunology

    2024  Volume 20, Issue 5, Page(s) 435–440

    Abstract: Introduction: Targeting IL-17A using Secukinumab, a humanized monoclonal immunoglobulin G1 (IgG1)/κ against IL-17A is a therapeutic option for immune-mediated disorders such as psoriasis and ankylosing spondylitis. The US Food and Drug Administration ... ...

    Abstract Introduction: Targeting IL-17A using Secukinumab, a humanized monoclonal immunoglobulin G1 (IgG1)/κ against IL-17A is a therapeutic option for immune-mediated disorders such as psoriasis and ankylosing spondylitis. The US Food and Drug Administration and the European Medicines Agency have approved it for the treatment of moderate to severe plaque psoriasis, active psoriatic arthritis, ankylosing spondylitis, and non-radiographic axial spondylarthritis. Recently it has also been approved for use in children with severe plaque psoriasis, active psoriatic arthritis, and enthesitis-related arthritis.
    Areas covered: This review focuses on the role of Secukinumab in the management of children and adolescents with enthesitis-related arthritis and psoriatic arthritis. We discuss the salient findings of pivotal RCTs and other studies supporting the use of Secukinumab in adults and children, in particular, focusing on its safety and efficacy.
    Expert opinion: Secukinumab is a therapeutic target for psoriasis, psoriatic arthritis, and spondyloarthropathies in both adults and children. No major safety signals are observed with its use in short-term follow-up. Thus far, Secukinumab has not been found to significantly increase the risk of tuberculosis (TB).
    MeSH term(s) Adult ; Child ; Adolescent ; Humans ; Arthritis, Psoriatic/drug therapy ; Interleukin-17/therapeutic use ; Spondylitis, Ankylosing/drug therapy ; Antibodies, Monoclonal/therapeutic use ; Psoriasis/drug therapy ; Arthritis, Juvenile/drug therapy ; Antibodies, Monoclonal, Humanized
    Chemical Substances secukinumab (DLG4EML025) ; Interleukin-17 ; Antibodies, Monoclonal ; Antibodies, Monoclonal, Humanized
    Language English
    Publishing date 2024-01-10
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2274260-8
    ISSN 1744-8409 ; 1744-666X
    ISSN (online) 1744-8409
    ISSN 1744-666X
    DOI 10.1080/1744666X.2024.2303340
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6661: Show issues Location:
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  5. Article ; Online: Hemophagocytic Lymphohistiocytosis: manifestation of an untamed immune system.

    Bagri, Narendra Kumar

    Indian journal of pediatrics

    2020  Volume 87, Issue 7, Page(s) 493–494

    MeSH term(s) Child ; Humans ; Immune System ; Lymphohistiocytosis, Hemophagocytic
    Language English
    Publishing date 2020-05-26
    Publishing country India
    Document type Editorial ; Comment
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-020-03348-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 826: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  6. Article: Extensive ulcerative lesions in juvenile dermatomyositis.

    Bagri, Narendra Kumar / Manas, Raj Kumar

    The Indian journal of medical research

    2022  Volume 152, Issue Suppl 1, Page(s) S238

    MeSH term(s) Biopsy ; Dermatomyositis/diagnosis ; Dermatomyositis/pathology ; Humans
    Language English
    Publishing date 2022-03-08
    Publishing country India
    Document type Journal Article
    ZDB-ID 390883-5
    ISSN 0971-5916 ; 0019-5340
    ISSN 0971-5916 ; 0019-5340
    DOI 10.4103/ijmr.IJMR_2410_19
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ua VI Zs.143: Show issues Location:
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  7. Article ; Online: Cyclosporine for Systemic Onset Juvenile Idiopathic Arthritis: Current Stand and Future Directions.

    Bagri, Narendra Kumar

    Indian journal of pediatrics

    2019  Volume 86, Issue 7, Page(s) 576–577

    MeSH term(s) Arthritis, Juvenile ; Biological Products ; Cyclosporine ; Humans
    Chemical Substances Biological Products ; Cyclosporine (83HN0GTJ6D)
    Language English
    Publishing date 2019-06-01
    Publishing country India
    Document type Editorial ; Review ; Comment
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-019-02985-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 826: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  8. Article ; Online: Medullary Necrosis in Acute Leukemia Mimicking as JIA.

    Bagri, Narendra Kumar / Singla, Tanya / Jana, Manisha

    Indian journal of pediatrics

    2023  

    Language English
    Publishing date 2023-06-14
    Publishing country India
    Document type Journal Article
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-023-04699-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 826: Show issues Location:
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  9. Article ; Online: Scope of JAK Inhibitors in Children: Recent Evidence and Way Forward.

    Bagri, Narendra Kumar / Chew, Christine / Ramanan, A V

    Paediatric drugs

    2023  Volume 25, Issue 6, Page(s) 635–647

    Abstract: Over the last decade, there has been an increase in the use of targeted therapy using small molecules such as Janus kinase (JAK) inhibitors. Since the introduction of ruxolitinib, the first non-selective JAK inhibitor approved for use in myelofibrosis, ... ...

    Abstract Over the last decade, there has been an increase in the use of targeted therapy using small molecules such as Janus kinase (JAK) inhibitors. Since the introduction of ruxolitinib, the first non-selective JAK inhibitor approved for use in myelofibrosis, many other JAK inhibitors have been tried in a wide spectrum of immune-mediated disorders. Although various trials have shown the promising efficacy of JAK inhibitors in immune-mediated inflammatory disorders (IMIDs), there is a growing concern over the major cardiovascular events and malignancies associated with the use of these molecules in older adults, particularly those over 65 years of age. In this review, we aim to discuss the immunology of the JAK-STAT pathway, the scope of use of JAK inhibitors, and their safety in paediatric practice. Here, we discuss high-quality evidence favouring the use of JAK inhibitors in children with juvenile idiopathic arthritis (JIA) who are refractory to one or more conventional/biological disease-modifying drugs, demonstrated in two randomised controlled trials (RCTs). In addition to JIA, there are reports favouring the role of JAK inhibitors in other IMIDs such as systemic-onset JIA and interferonopathies. Thus far, the existing literature suggests an acceptable safety profile for JAK inhibitors in children. With the expanding scope of JAK inhibitors in a wide range of IMIDs in children, there is a significant need for long-term close vigilance for any potential harm.
    MeSH term(s) Child ; Humans ; Aged ; Janus Kinase Inhibitors/adverse effects ; Immunomodulating Agents ; Neoplasms/drug therapy
    Chemical Substances Janus Kinase Inhibitors ; Immunomodulating Agents
    Language English
    Publishing date 2023-09-29
    Publishing country Switzerland
    Document type Review ; Journal Article
    ZDB-ID 1492748-2
    ISSN 1179-2019 ; 1174-5878
    ISSN (online) 1179-2019
    ISSN 1174-5878
    DOI 10.1007/s40272-023-00594-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5205: Show issues Location:
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  10. Article ; Online: Infantile Takayasu arteritis: how is it different?

    Kushwah, Sunil / Ramanan, Athimalaipet V / Bagri, Narendra Kumar

    Rheumatology (Oxford, England)

    2023  Volume 62, Issue 9, Page(s) 2946–2947

    MeSH term(s) Humans ; Takayasu Arteritis/diagnosis ; Infant ; Child, Preschool
    Language English
    Publishing date 2023-03-27
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 1464822-2
    ISSN 1462-0332 ; 1462-0324
    ISSN (online) 1462-0332
    ISSN 1462-0324
    DOI 10.1093/rheumatology/kead131
    Database MEDical Literature Analysis and Retrieval System OnLINE

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