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  1. Article ; Online: Circular RNAs: Diagnostic and Therapeutic Perspectives in CNS Diseases.

    Bai, Ying / Yao, Hong-Hong

    Current medical science

    2023  Volume 43, Issue 5, Page(s) 879–889

    Abstract: Circular RNAs (circRNAs) are a class of regulatory non-coding RNAs characterized by the presence of covalently closed ends. A growing body of evidence suggests that circRNAs play important roles in physiology and pathology. In particular, accumulating ... ...

    Abstract Circular RNAs (circRNAs) are a class of regulatory non-coding RNAs characterized by the presence of covalently closed ends. A growing body of evidence suggests that circRNAs play important roles in physiology and pathology. In particular, accumulating data on circRNA functions in various central nervous system (CNS) diseases and their correlations indicate that circRNAs are critical contributors to the onset and development of brain disorders. In this review, we focus on the regulatory and functional roles of circRNAs in CNS diseases, highlighting their diagnostic and therapeutic potential, with the aim of providing new insights into CNS diseases.
    MeSH term(s) Humans ; RNA, Circular/genetics ; RNA/genetics ; Central Nervous System Diseases/diagnosis ; Central Nervous System Diseases/genetics ; Central Nervous System Diseases/therapy ; Brain Diseases/diagnosis ; Brain Diseases/genetics ; Brain Diseases/therapy
    Chemical Substances RNA, Circular ; RNA (63231-63-0)
    Language English
    Publishing date 2023-10-10
    Publishing country China
    Document type Review ; Journal Article
    ZDB-ID 2931065-9
    ISSN 2523-899X ; 2096-5230
    ISSN (online) 2523-899X
    ISSN 2096-5230
    DOI 10.1007/s11596-023-2784-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: [Class concept: annotation and application in classical prescriptions].

    Bai, Ying-Zhe / Huang, Lu-Qi

    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

    2023  Volume 48, Issue 13, Page(s) 3678–3683

    Abstract: The study of classical prescriptions should probe into not only the history but also the formation methodology. As a representative of the logic thoughts in ancient China, the class concept has gone through long history, with the theoretical system ... ...

    Abstract The study of classical prescriptions should probe into not only the history but also the formation methodology. As a representative of the logic thoughts in ancient China, the class concept has gone through long history, with the theoretical system completed by Biemo in the late Warring States period. The Mohist school, proposing the class concept, plays an important role in the history of Chinese logic and world logic, and its theory has also been inherited and developed by scholars of the same era and later generations. The study of the class concept will contribute to the integration of scientific methodologies between the east and the west. Exploring the impact of the class concept on traditional Chinese medicine(TCM), especially the application in classical prescriptions, may be a path worth exploring for further studying the thought of the Treatise on Febrile and Miscellaneous Diseases(Shang Han Za Bing Lun).
    MeSH term(s) Medicine, Chinese Traditional ; China ; Prescriptions ; Drugs, Chinese Herbal
    Chemical Substances Drugs, Chinese Herbal
    Language Chinese
    Publishing date 2023-07-20
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 1004649-5
    ISSN 1001-5302 ; 0254-0029
    ISSN 1001-5302 ; 0254-0029
    DOI 10.19540/j.cnki.cjcmm.20230411.601
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3056: Show issues Location:
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  3. Article ; Online: Siloxane-containing phosphine (oxide) ligands for enhanced catalytic activity of cobalt complexes for hydrosilylation reactions.

    Liu, Peng / Peng, Jiajian / Bai, Ying / Li, Jiayun

    Organic & biomolecular chemistry

    2024  Volume 22, Issue 16, Page(s) 3304–3313

    Abstract: A series of siloxane-containing phosphine (oxide) ligands have been designed and synthesized. These phosphine (oxide) ligands contain silicon atoms, which can impart better solubility in the relevant media, thereby improving certain catalytic ... ...

    Abstract A series of siloxane-containing phosphine (oxide) ligands have been designed and synthesized. These phosphine (oxide) ligands contain silicon atoms, which can impart better solubility in the relevant media, thereby improving certain catalytic performances. The hydrosilylation of olefins catalyzed by these metal phosphine (oxide) complexes has been conducted under mild reaction conditions.
    Language English
    Publishing date 2024-04-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 2097583-1
    ISSN 1477-0539 ; 1477-0520
    ISSN (online) 1477-0539
    ISSN 1477-0520
    DOI 10.1039/d4ob00333k
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Discovery of Palbociclib as a potent c-Myc G4 stabilizer for lung cancer treatment using molecular docking, molecular dynamics simulation, and in vitro activity evaluation.

    Gao, Jian / Liang, Chao / Yin, Jiacheng / Bai, Ying / Hu, Dong

    Molecular diversity

    2024  

    Abstract: Despite significant progress in lung cancer treatment, this disease remains a prevalent and serious global malignancy, leading to high rates of illness and death. Urgent research is needed to discover new or alternative therapies that can improve ... ...

    Abstract Despite significant progress in lung cancer treatment, this disease remains a prevalent and serious global malignancy, leading to high rates of illness and death. Urgent research is needed to discover new or alternative therapies that can improve clinical outcomes for lung cancer patients. In our study, we successfully demonstrated the effectiveness of Palbociclib, a CDK4/6 inhibitor, in suppressing the growth of lung cancer cells. The IC
    Language English
    Publishing date 2024-01-22
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1376507-3
    ISSN 1573-501X ; 1381-1991
    ISSN (online) 1573-501X
    ISSN 1381-1991
    DOI 10.1007/s11030-023-10789-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4946: Show issues Location:
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  5. Article: Corrigendum: Development of a quadruplex PCR amplicon next generation sequencing assay for detection and differentiation of

    Bai, Ying / Osikowicz, Lynn M / Hojgaard, Andrias / Eisen, Rebecca J

    Frontiers in microbiology

    2024  Volume 15, Page(s) 1360286

    Abstract: This corrects the article DOI: 10.3389/fmicb.2023.1243471.]. ...

    Abstract [This corrects the article DOI: 10.3389/fmicb.2023.1243471.].
    Language English
    Publishing date 2024-02-26
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2024.1360286
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Ultra-High Temperature Operated Ni-Rich Cathode Stabilized by Thermal Barrier for High-Energy Lithium-Ion Batteries.

    Dai, Zhongsheng / Liu, Yun / Lu, Xia / Zhao, Huiling / Bai, Ying

    Advanced materials (Deerfield Beach, Fla.)

    2024  , Page(s) e2313500

    Abstract: The pursuit of high energy density batteries has expedited the fast development of Ni-rich cathodes. However, the chemo-mechanical degradation induced by local thermal accumulation and anisotropic lattice strain is posing great obstacles for its wide ... ...

    Abstract The pursuit of high energy density batteries has expedited the fast development of Ni-rich cathodes. However, the chemo-mechanical degradation induced by local thermal accumulation and anisotropic lattice strain is posing great obstacles for its wide applications. Herein, a highly-antioxidative BaZrO
    Language English
    Publishing date 2024-03-12
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1474949-X
    ISSN 1521-4095 ; 0935-9648
    ISSN (online) 1521-4095
    ISSN 0935-9648
    DOI 10.1002/adma.202313500
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Aquaporins in lacrimal glands and their role in dry eye disease.

    Bai, Ying / Zhang, Kaier / Cao, Xin / Chen, Peng

    Experimental eye research

    2023  Volume 236, Page(s) 109676

    Abstract: Aging is the most important known risk factor for dry eye is aging, which is associated with changes in the structure and function of the lacrimal gland (LG) and characterized by atrophy, duct blocking lymphocyte infiltration, and reduced protein ... ...

    Abstract Aging is the most important known risk factor for dry eye is aging, which is associated with changes in the structure and function of the lacrimal gland (LG) and characterized by atrophy, duct blocking lymphocyte infiltration, and reduced protein secretion. Aquaporins (AQP) have been proposed as a potential producer of exocrine gland fluids since exocrine secretion depends on the mobility of water. Therefore, the main topics of this review will be the expression, localization, and function of AQPs in LG. In addition, we review the mechanisms of fluid transport in exocrine gland fluid secretion and discuss the potential role of AQPs in dry eye.
    MeSH term(s) Humans ; Lacrimal Apparatus/metabolism ; Aquaporins/metabolism ; Dry Eye Syndromes/metabolism ; Biological Transport
    Chemical Substances Aquaporins
    Language English
    Publishing date 2023-10-10
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 80122-7
    ISSN 1096-0007 ; 0014-4835
    ISSN (online) 1096-0007
    ISSN 0014-4835
    DOI 10.1016/j.exer.2023.109676
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 163: Show issues Location:
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  8. Article ; Online: The immunometabolic landscape of bone marrow cells in multiple sclerosis.

    Shi, Yutong / Qi, Caiyun / Bai, Ying

    FASEB journal : official publication of the Federation of American Societies for Experimental Biology

    2023  Volume 37, Issue 11, Page(s) e23267

    Abstract: In multiple sclerosis (MS), the bone marrow hematopoietic system supplies immune cells to orchestrate central nervous system (CNS) inflammation and autoimmunity. Understanding the metabolic processes within the bone marrow is essential for unraveling the ...

    Abstract In multiple sclerosis (MS), the bone marrow hematopoietic system supplies immune cells to orchestrate central nervous system (CNS) inflammation and autoimmunity. Understanding the metabolic processes within the bone marrow is essential for unraveling the phenotype and function of immune cells. However, a comprehensive exploration of the metabolic landscape and its association with systemic immune response in MS at the single-cell level has yet to be elucidated. Herein, we conducted an analysis of 70 289 bone marrow cells obtained from seven patients with MS and seven health controls (referenced as HRA001783) to address this question. Our focus was primarily on investigating the metabolic preferences of diverse immune cell populations and delineating their metabolic manifestations in the bone marrow microenvironment of MS. Through our analysis, we observed the activation of carbohydrate and amino acid metabolic pathways in the bone marrow cells of MS patients. Notably, we discovered significant metabolic alterations in cell-cell communication within the plasma cell population in the MS bone marrow. These findings shed light on the complex metabolic landscape within the bone marrow niche during MS and highlight the distinctive metabolic characteristics of plasma cells in this context, which may provoke novel understanding of MS pathogenesis and promote future design of immune therapies.
    MeSH term(s) Humans ; Multiple Sclerosis ; Bone Marrow Cells ; Central Nervous System ; Amino Acids ; Autoimmunity
    Chemical Substances Amino Acids
    Language English
    Publishing date 2023-10-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639186-2
    ISSN 1530-6860 ; 0892-6638
    ISSN (online) 1530-6860
    ISSN 0892-6638
    DOI 10.1096/fj.202300694R
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2266: Show issues Location:
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    Zs.MO 296: Show issues

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  9. Article ; Online: A cobalt-doped hollow ZnS polyhedra@porous carbon shell composite anode for high-rate sodium-ion batteries.

    Di, Miaoxin / Song, Zhenqi / Chen, Suhua / Bai, Ying

    Nanoscale

    2023  Volume 15, Issue 47, Page(s) 19159–19167

    Abstract: Transition metal sulfides (TMSs) have drawn promising attention due to their low cost and high theoretical capacity for sodium storage. However, the critical issues of TMSs with huge volume changes and lower ionic/electronic conductivity are the major ... ...

    Abstract Transition metal sulfides (TMSs) have drawn promising attention due to their low cost and high theoretical capacity for sodium storage. However, the critical issues of TMSs with huge volume changes and lower ionic/electronic conductivity are the major challenges for their practical application in sodium-ion batteries. Herein, we constructed cobalt-doped ZnS encapsulated in an N-doped carbon shell (denoted as Co-ZnS@NC), which effectively alleviates the volume expansion and improves sodium storage performance. The mechanism analysis and ion diffusion kinetics analysis (GITT, EIS, and CV) prove the acceleration of Na
    Language English
    Publishing date 2023-12-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2515664-0
    ISSN 2040-3372 ; 2040-3364
    ISSN (online) 2040-3372
    ISSN 2040-3364
    DOI 10.1039/d3nr03597b
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Driving factors on accumulation of cadmium, lead, copper, zinc in agricultural soil and products of the North China Plain.

    Liu, Zheng / Bai, Ying / Gao, Junhong / Li, Jun

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 7429

    Abstract: The accumulation of heavy metals in agricultural soils concerns food security. By using the Geographical Detector, this study investigated the influence of six types of factors (eleven factors) on the accumulation of Cd, Pb, Cu, Zn in agricultural soil ... ...

    Abstract The accumulation of heavy metals in agricultural soils concerns food security. By using the Geographical Detector, this study investigated the influence of six types of factors (eleven factors) on the accumulation of Cd, Pb, Cu, Zn in agricultural soil and products of the North China Plain and confirmed the dominant factor. The results showed that heavy metals had accumulated in regional agricultural soils and the accumulation of Cd was severe. The accumulation of heavy metals was significantly influenced by policy factors (the management and reduction in usage of fertilizers and pesticides), fertilization factors (application of organic and chemical fertilizers), pesticide factors (application of herbicide and insecticide) and atmospheric deposition factors (heavy metal concentration in atmospheric deposition). The policy factor dominated the other three types of factors. Atmospheric deposition and the excess application of fertilizers and pesticides directly lead to the accumulation of heavy metals. Due to the high concentrations of heavy metals and abundant application amounts, organic fertilizers have contributed high levels of heavy metals to agricultural soils. This study suggests that formulated fertilization and action plans for pesticide reduction could effectively decrease the accumulation of heavy metals in agricultural soils and products in the study area.
    Language English
    Publishing date 2023-05-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-34688-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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