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  1. AU="Bailey, Mark"
  2. AU="Li-Feng Han"
  3. AU="Jennifer Tremblay-Mercier"
  4. AU=Abouzied Mohei M
  5. AU="Eckardstein, Arnold von"
  6. AU="Häberle, Ramona"
  7. AU="Tsikari, Theano"
  8. AU="Mawutorli Nyarku"
  9. AU="Dene R. Littler"
  10. AU="Zamai, Loris"
  11. AU=Kato Takashi
  12. AU=Haase Michael
  13. AU="Ingrams, Duncan"
  14. AU=Liu Rong
  15. AU="Musselman, Kristin E"
  16. AU=Abrams M J
  17. AU="Paul, Archi Sundar"
  18. AU=Yoon Hyuk
  19. AU="Gonzalez, Emily"
  20. AU="Dunnill, M S"
  21. AU=Kuo Chih-Hung
  22. AU=Geronimo Carly L.
  23. AU=Stafforini D M
  24. AU="Sytse J. Piersma"
  25. AU="Peng, Hongke"
  26. AU="Kelly, Geoffrey"
  27. AU=Schwartzenburg Joshua AU=Schwartzenburg Joshua
  28. AU="Deshpande, Sneha Satish"
  29. AU="Ganhewa, Aparna D" AU="Ganhewa, Aparna D"
  30. AU="Flanagan, T L"
  31. AU=Davila Eduardo
  32. AU="Miroli, Augusto"
  33. AU="Stahl, B"
  34. AU="Dehari, Hironari"
  35. AU="Pinheiro, Silviane Bezerra"
  36. AU="Jamal Al Deen Alkoteesh"
  37. AU="Chen, Dingqiang"
  38. AU="Jeremy C. Ganz"
  39. AU="Lee, Ta-Sheng"
  40. AU="Shi, Jin-Ming"
  41. AU=Kristoffersen K B
  42. AU=Du Chao
  43. AU="Anton I. Skaro"

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  1. Buch ; Online: Could AI be the Great Filter? What Astrobiology can Teach the Intelligence Community about Anthropogenic Risks

    Bailey, Mark M.

    2023  

    Abstract: Where is everybody? This phrase distills the foreboding of what has come to be known as the Fermi Paradox - the disquieting idea that, if extraterrestrial life is probable in the Universe, then why have we not encountered it? This conundrum has puzzled ... ...

    Abstract Where is everybody? This phrase distills the foreboding of what has come to be known as the Fermi Paradox - the disquieting idea that, if extraterrestrial life is probable in the Universe, then why have we not encountered it? This conundrum has puzzled scholars for decades, and many hypotheses have been proposed suggesting both naturalistic and sociological explanations. One intriguing hypothesis is known as the Great Filter, which suggests that some event required for the emergence of intelligent life is extremely unlikely, hence the cosmic silence. A logically equivalent version of this hypothesis -- and one that should give us pause -- suggests that some catastrophic event is likely to occur that prevents life's expansion throughout the cosmos. This could be a naturally occurring event, or more disconcertingly, something that intelligent beings do to themselves that leads to their own extinction. From an intelligence perspective, framing global catastrophic risk (particularly risks of anthropogenic origin) within the context of the Great Filter can provide insight into the long-term futures of technologies that we don't fully understand, like artificial intelligence. For the intelligence professional concerned with global catastrophic risk, this has significant implications for how these risks ought to be prioritized.

    Comment: 19 pages, 2 figures
    Schlagwörter Computer Science - Computers and Society ; Computer Science - Artificial Intelligence ; Physics - Physics and Society
    Erscheinungsdatum 2023-05-09
    Erscheinungsland us
    Dokumenttyp Buch ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  2. Buch ; Online: Chapter 5 Impacts and Environmental Risks of Oil Spills on Marine Invertebrates, Algae and Seagrass : A Global Review from an Australian Perspective

    Keesing, John K. / Gartner, Adam / Westera, Mark / Edgar, Graham J. / Myers, Joanne / Hardman-Mountford, Nick J. / Bailey, Mark

    2018  

    Schlagwörter Marine biology ; Oceanography (seas) ; Wildlife: aquatic creatures ; Environmental science, engineering & technology ; oil spills, marine life, marine invertebrates, algae, seagrass, ocean toxicity, marine habitats, Australian marine life, oil spill Australia
    Umfang 1 electronic resource (61 pages)
    Verlag Taylor and Francis
    Dokumenttyp Buch ; Online
    Anmerkung English ; Open Access
    HBZ-ID HT021051607
    ISBN 9780429454455 ; 0429454457
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  3. Buch ; Konferenzbeitrag: Microbial ecology of aerial plant surfaces

    Bailey, Mark J.

    [2005 ... at St. Catherine's College, Oxford]

    2006  

    Veranstaltung/Kongress International Symposium on the Microbiology of Aerial Plant Surfaces (8, 2005, Oxford)
    Verfasserangabe [International Symposium on the Microbiology of Aerial Plant Surfaces]. Ed. by M. J. Bailey
    Sprache Englisch
    Umfang XVIII, 315 S. : Ill., graph. Darst.
    Verlag CABI
    Erscheinungsort Wallingford u.a.
    Erscheinungsland Vereinigtes Königreich
    Dokumenttyp Buch ; Konferenzbeitrag
    HBZ-ID HT014638905
    ISBN 1-84593-061-4 ; 978-1-84593-061-5
    Datenquelle Katalog ZB MED Ernährung, Umwelt, Agrar

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  4. Artikel ; Online: Celebrating 15 years of The ISME Journal.

    Kowalchuk, George A / Bailey, Mark J

    The ISME journal

    2023  Band 17, Heft 7, Seite(n) 950–951

    Sprache Englisch
    Erscheinungsdatum 2023-04-12
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2406536-5
    ISSN 1751-7370 ; 1751-7362
    ISSN (online) 1751-7370
    ISSN 1751-7362
    DOI 10.1038/s41396-023-01413-0
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: A stable start: cotranslational Nt-acetylation promotes proteome stability across kingdoms.

    Gibbs, Daniel J / Bailey, Mark / Etherington, Ross D

    Trends in cell biology

    2022  Band 32, Heft 5, Seite(n) 374–376

    Abstract: Two recent studies show that cotranslational N-terminal protein acetylation (NTA) promotes proteome stability in humans (Mueller et al.) and plants (Linster et al.) by masking nonacetylated N-degrons that would otherwise destabilise proteins. This is in ... ...

    Abstract Two recent studies show that cotranslational N-terminal protein acetylation (NTA) promotes proteome stability in humans (Mueller et al.) and plants (Linster et al.) by masking nonacetylated N-degrons that would otherwise destabilise proteins. This is in contrast to previous findings linking NTA to degradation, suggesting that this widespread mark has complex and context-specific functions in regulating protein half-lives.
    Mesh-Begriff(e) Acetylation ; Humans ; Plants/metabolism ; Protein Processing, Post-Translational ; Proteolysis ; Proteome/metabolism
    Chemische Substanzen Proteome
    Sprache Englisch
    Erscheinungsdatum 2022-03-05
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 30122-x
    ISSN 1879-3088 ; 0962-8924
    ISSN (online) 1879-3088
    ISSN 0962-8924
    DOI 10.1016/j.tcb.2022.02.004
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  6. Artikel: Medical and DNBI admissions to the Role 3 field hospital at Camp Bastion during Operation Herrick.

    Bailey, Mark S

    Journal of the Royal Army Medical Corps

    2016  Band 162, Heft 1, Seite(n) 76–77

    Mesh-Begriff(e) Female ; Hospitalization/statistics & numerical data ; Hospitals, Military/statistics & numerical data ; Humans ; Internal Medicine/statistics & numerical data ; Male ; Military Personnel/statistics & numerical data
    Sprache Englisch
    Erscheinungsdatum 2016-02
    Erscheinungsland England
    Dokumenttyp Comment ; Letter
    ZDB-ID 840678-9
    ISSN 2052-0468 ; 0035-8665
    ISSN (online) 2052-0468
    ISSN 0035-8665
    DOI 10.1136/jramc-2015-000551
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  7. Artikel: Evaluation of Alternative Doxycycline Antibiotic Regimes in an Inhalational Murine Model of Q Fever.

    Clay, Kate A / Hartley, M Gill / Whelan, Adam O / Bailey, Mark S / Norville, Isobel H

    Antibiotics (Basel, Switzerland)

    2023  Band 12, Heft 5

    Abstract: The timing of the initiation of antibiotic treatment has been shown to impact the clinical outcome of many bacterial infections, including Q fever. Delayed, suboptimal or incorrect antibiotic treatment has been shown to result in poor prognosis, ... ...

    Abstract The timing of the initiation of antibiotic treatment has been shown to impact the clinical outcome of many bacterial infections, including Q fever. Delayed, suboptimal or incorrect antibiotic treatment has been shown to result in poor prognosis, resulting in the progression of acute disease to long-term chronic sequalae. Therefore, there is a requirement to identify an optimal, effective therapeutic regimen to treat acute Q fever. In the study, the efficacies of different doxycycline monohydrate regimens (pre-exposure prophylaxis, post-exposure prophylaxis or treatment at symptom onset or resolution) were evaluated in an inhalational murine model of Q fever. Different treatment lengths (7 or 14 days) were also evaluated. Clinical signs and weight loss were monitored during infection and mice were euthanized at different time points to characterize bacterial colonization in the lungs and the dissemination of bacteria to other tissues including the spleen, brain, testes, bone marrow and adipose. Post-exposure prophylaxis or doxycycline treatment starting at symptoms onset reduced clinical signs, and also delayed the systemic clearance of viable bacteria from key tissues. Effective clearance was dependent on the development of an adaptive immune response, but also driven by sufficient bacterial activity to maintain an active immune response. Pre-exposure prophylaxis or post-exposure treatment at the resolution of clinical signs did not improve outcomes. These are the first studies to experimentally evaluate different doxycycline treatment regimens for Q fever and illustrate the need to explore the efficacy of other novel antibiotics.
    Sprache Englisch
    Erscheinungsdatum 2023-05-16
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics12050914
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  8. Buch ; Online: Examining the Differential Risk from High-level Artificial Intelligence and the Question of Control

    Kilian, Kyle A. / Ventura, Christopher J. / Bailey, Mark M.

    2022  

    Abstract: Artificial Intelligence (AI) is one of the most transformative technologies of the 21st century. The extent and scope of future AI capabilities remain a key uncertainty, with widespread disagreement on timelines and potential impacts. As nations and ... ...

    Abstract Artificial Intelligence (AI) is one of the most transformative technologies of the 21st century. The extent and scope of future AI capabilities remain a key uncertainty, with widespread disagreement on timelines and potential impacts. As nations and technology companies race toward greater complexity and autonomy in AI systems, there are concerns over the extent of integration and oversight of opaque AI decision processes. This is especially true in the subfield of machine learning (ML), where systems learn to optimize objectives without human assistance. Objectives can be imperfectly specified or executed in an unexpected or potentially harmful way. This becomes more concerning as systems increase in power and autonomy, where an abrupt capability jump could result in unexpected shifts in power dynamics or even catastrophic failures. This study presents a hierarchical complex systems framework to model AI risk and provide a template for alternative futures analysis. Survey data were collected from domain experts in the public and private sectors to classify AI impact and likelihood. The results show increased uncertainty over the powerful AI agent scenario, confidence in multiagent environments, and increased concern over AI alignment failures and influence-seeking behavior.

    Comment: 44 pages
    Schlagwörter Computer Science - Artificial Intelligence ; Computer Science - Computers and Society ; Computer Science - Human-Computer Interaction
    Thema/Rubrik (Code) 910
    Erscheinungsdatum 2022-11-06
    Erscheinungsland us
    Dokumenttyp Buch ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  9. Artikel ; Online: Characterization of asbestiform glaucophane-winchite in the Franciscan Complex blueschist, northern Diablo Range, California.

    Erskine, Bradley G / Bailey, Mark

    Toxicology and applied pharmacology

    2018  Band 361, Seite(n) 3–13

    Abstract: This paper presents a geologic and mineralogical investigation of asbestiform amphibole from blueschist in the Diablo Range, northern California. The analysis of fibers in air samples shows that the dominant blueschist amphibole composition ranges from ... ...

    Abstract This paper presents a geologic and mineralogical investigation of asbestiform amphibole from blueschist in the Diablo Range, northern California. The analysis of fibers in air samples shows that the dominant blueschist amphibole composition ranges from glaucophane to subordinate winchite. In outcrop, blueschist amphibole exhibits a velvety luster, and its occurrence ranges from crosscutting veins to highly deformed foliated and lineated tectonites. TEM and SEM photographs reveal a highly fibrous habit typically associated with asbestiform amphiboles. Dimensional analysis reveals a mean fiber width of 0.27 μm, and lengths and aspect ratios are shorter than reported for commercially exploitable asbestos, with a mean length of 2.8 μm and mean aspect ratio of 11.5. The data are consistent with other research showing that the width population of fibers, and not length or aspect ratio, is the key indicator of the asbestiform habit. The blueschist data are compared to non-asbestiform hornblende amphibole in granitic rocks. The fiber concentration of the hornblende (458 MFG) is low compared to the blueschist amphibole (107,880 MFG) and chrysotile in serpentinite (196,066 MFG), indicating that under similar conditions, the exposure potential from cleaved particles could be several orders of magnitude lower than from asbestiform particles. The asbestiform habit of glaucophane is present at two other locations in the Franciscan Complex, suggesting that asbestiform blueschist amphibole may be characteristic within blueschist terranes, and rock formations containing asbestiform amphibole may be more common and widespread than previously assumed.
    Mesh-Begriff(e) Air Pollutants, Occupational/analysis ; Asbestos, Amphibole/analysis ; Asbestos, Serpentine/analysis ; California ; Environmental Monitoring ; Humans ; Microscopy, Electron, Scanning ; Microscopy, Electron, Transmission ; Minerals/analysis ; Particle Size
    Chemische Substanzen Air Pollutants, Occupational ; Asbestos, Amphibole ; Asbestos, Serpentine ; Minerals
    Sprache Englisch
    Erscheinungsdatum 2018-09-19
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 204477-8
    ISSN 1096-0333 ; 0041-008X
    ISSN (online) 1096-0333
    ISSN 0041-008X
    DOI 10.1016/j.taap.2018.09.020
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  10. Artikel ; Online: Horizontal gene transfer in the phytosphere.

    Van Elsas, Jan Dirk / Turner, Sarah / Bailey, Mark J

    The New phytologist

    2020  Band 157, Heft 3, Seite(n) 525–537

    Abstract: Here, the ecological aspects of gene transfer processes between bacteria in the phytosphere are examined in the context of emerging evidence for the dominant role that horizontal gene transfer (HGT) has played in the evolutionary shaping of bacterial ... ...

    Abstract Here, the ecological aspects of gene transfer processes between bacteria in the phytosphere are examined in the context of emerging evidence for the dominant role that horizontal gene transfer (HGT) has played in the evolutionary shaping of bacterial communities. Moreover, the impact of the putative capture of genetic material by bacteria from plants is discussed. Examples are provided that illustrate how mobile genetic elements (MGEs) influence the behaviour of bacteria in their natural habitat, especially in structured communities such as biofilms on plant surfaces. This community behaviour is used as a framework to pose questions on the evolutionary role and significance of gene transfer processes in plant-associated habitats. Selection within the highly structured phytosphere is likely to represent a dominant force shaping the genetic make-up of plant-associated bacterial communities. Current understanding of the triggering and impact of horizontal gene transfer, however, remains limited by our lack of understanding of the nature of the selective forces that act on bacteria in situ. The individual, colony, population and community level selection benefits imposed by the ability to use specific carbon sources or survive selective compounds are clear, but it is not always possible to assess what drives gene transfer and persistence. The role of HGT in the adaptation of host bacteria to their environmental niche is still not fully understood.
    Sprache Englisch
    Erscheinungsdatum 2020-10-16
    Erscheinungsland England
    Dokumenttyp Journal Article ; Review
    ZDB-ID 208885-x
    ISSN 1469-8137 ; 0028-646X
    ISSN (online) 1469-8137
    ISSN 0028-646X
    DOI 10.1046/j.1469-8137.2003.00697.x
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