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  1. Article ; Online: SARS-CoV-2 infection despite vaccination: an under-reported COVID-19 cohort.

    Robbins, Tim / Baitule, Sudhanshu / Kyrou, Ioannis / Ray, Pijush / Morgan, Nina / Berry, Lisa / Randeva, Harpal

    Clinical medicine (London, England)

    2021  Volume 21, Issue 2, Page(s) e243

    MeSH term(s) COVID-19 ; Humans ; Reinfection ; SARS-CoV-2 ; United Kingdom ; Vaccination
    Language English
    Publishing date 2021-03-24
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2048646-7
    ISSN 1473-4893 ; 1470-2118
    ISSN (online) 1473-4893
    ISSN 1470-2118
    DOI 10.7861/clinmed.Let.21.2.6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A Systematic Review to Assess the Impact of Hyperbaric Oxygen Therapy on Glycaemia in People with Diabetes Mellitus.

    Baitule, Sudhanshu / Patel, Aaran H / Murthy, Narasimha / Sankar, Sailesh / Kyrou, Ioannis / Ali, Asad / Randeva, Harpal S / Robbins, Tim

    Medicina (Kaunas, Lithuania)

    2021  Volume 57, Issue 10

    Abstract: Background and ... ...

    Abstract Background and Objectives
    MeSH term(s) Blood Glucose ; Diabetes Mellitus, Type 2 ; Diabetic Foot/therapy ; Humans ; Hyperbaric Oxygenation ; Prospective Studies
    Chemical Substances Blood Glucose
    Language English
    Publishing date 2021-10-19
    Publishing country Switzerland
    Document type Journal Article ; Review ; Systematic Review
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina57101134
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Hyperbaric oxygen therapy for the treatment of long COVID: early evaluation of a highly promising intervention.

    Robbins, Tim / Gonevski, Michael / Clark, Cain / Baitule, Sudhanshu / Sharma, Kavi / Magar, Angel / Patel, Kiran / Sankar, Sailesh / Kyrou, Ioannis / Ali, Asad / Randeva, Harpal S

    Clinical medicine (London, England)

    2021  Volume 21, Issue 6, Page(s) e629–e632

    Abstract: Background: Long COVID is a common occurrence following COVID-19 infection. The most common symptom reported is fatigue. Limited interventional treatment options exist. We report the first evaluation of hyperbaric oxygen therapy (HBOT) for long COVID ... ...

    Abstract Background: Long COVID is a common occurrence following COVID-19 infection. The most common symptom reported is fatigue. Limited interventional treatment options exist. We report the first evaluation of hyperbaric oxygen therapy (HBOT) for long COVID treatment.
    Methods: A total of 10 consecutive patients received 10 sessions of HBOT to 2.4 atmospheres over 12 days. Each treatment session lasted 105 minutes, consisting of three 30-minute exposures to 100% oxygen, interspersed with 5-minute air breaks. Validated fatigue and cognitive scoring assessments were performed at day 1 and 10. Statistical analysis was with Wilcoxon signed-rank testing reported alongside effect sizes.
    Results: HBOT yielded a statistically significant improvement in the Chalder fatigue scale (p=0.0059; d=1.75 (very large)), global cognition (p=0.0137; d=-1.07 (large)), executive function (p=0.0039; d=-1.06 (large)), attention (p=0.0020; d=-1.2 (very large)), information processing (p=0.0059; d=-1.25 (very large)) and verbal function (p=0.0098; d=-0.92 (large)).
    Conclusion: Long COVID-related fatigue can be debilitating, and may affect young people who were previously in economic employment. The results presented here suggest potential benefits of HBOT, with statistically significant results following 10 sessions.
    MeSH term(s) Adolescent ; COVID-19/complications ; Humans ; Hyperbaric Oxygenation ; Oxygen ; SARS-CoV-2 ; Post-Acute COVID-19 Syndrome
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2021-12-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 2048646-7
    ISSN 1473-4893 ; 1470-2118
    ISSN (online) 1473-4893
    ISSN 1470-2118
    DOI 10.7861/clinmed.2021-0462
    Database MEDical Literature Analysis and Retrieval System OnLINE

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