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  1. Article ; Online: Comment on: Comparison of supine and seated orthostatic hypotension assessments and their association with falls and orthostatic symptoms.

    Baker, Jacquie R / Raj, Satish R

    Journal of the American Geriatrics Society

    2022  Volume 71, Issue 2, Page(s) 673–674

    MeSH term(s) Humans ; Hypotension, Orthostatic/complications ; Hypotension, Orthostatic/diagnosis ; Blood Pressure
    Language English
    Publishing date 2022-11-10
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80363-7
    ISSN 1532-5415 ; 0002-8614
    ISSN (online) 1532-5415
    ISSN 0002-8614
    DOI 10.1111/jgs.18112
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    In stock of ZB MED Cologne/Königswinter

    Ud II Zs.168: Show issues Location:
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  2. Article ; Online: Recent updates in autonomic research: a focus on new technologies with high-resolution procedures to study sympathetic nerve activity, plasma proteomic profiling in POTS, and non-invasive neuromodulation with focused ultrasound.

    Baker, Jacquie R / Bourne, Kate M / Lamotte, Guillaume

    Clinical autonomic research : official journal of the Clinical Autonomic Research Society

    2023  Volume 33, Issue 1, Page(s) 11–14

    MeSH term(s) Humans ; Proteomics ; Sympathetic Nervous System ; Autonomic Nervous System ; Postural Orthostatic Tachycardia Syndrome ; Heart Rate/physiology
    Language English
    Publishing date 2023-01-20
    Publishing country Germany
    Document type Editorial
    ZDB-ID 1080007-4
    ISSN 1619-1560 ; 0959-9851
    ISSN (online) 1619-1560
    ISSN 0959-9851
    DOI 10.1007/s10286-023-00924-2
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    Zs.A 3270: Show issues Location:
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  3. Article ; Online: Autonomic Manifestations of Long-COVID Syndrome.

    Hira, Rashmin / Karalasingham, Kavithra / Baker, Jacquie R / Raj, Satish R

    Current neurology and neuroscience reports

    2023  Volume 23, Issue 12, Page(s) 881–892

    Abstract: Purpose of review: Long-COVID is a novel condition emerging from the COVID-19 pandemic. Long-COVID is characterized by symptoms commonly seen in autonomic disorders including fatigue, brain fog, light-headedness, and palpitations. This article will ... ...

    Abstract Purpose of review: Long-COVID is a novel condition emerging from the COVID-19 pandemic. Long-COVID is characterized by symptoms commonly seen in autonomic disorders including fatigue, brain fog, light-headedness, and palpitations. This article will critically evaluate recent findings and studies on Long-COVID and its physiological autonomic manifestations.
    Recent findings: Studies have reported on the prevalence of different symptoms and autonomic disorders in Long-COVID cohorts. Autonomic nervous system function, including both the parasympathetic and sympathetic limbs, has been studied using different testing techniques in Long-COVID patients. While numerous mechanisms may contribute to Long-COVID autonomic pathophysiology, it is currently unclear which ones lead to a Long-COVID presentation. To date, studies have not tested treatment options for autonomic disorders in Long-COVID patients. Long-COVID is associated with autonomic abnormalities. There is a high prevalence of clinical autonomic disorders among Long-COVID patients, with limited knowledge of the underlying mechanisms and the effectiveness of treatment options.
    MeSH term(s) Humans ; Post-Acute COVID-19 Syndrome ; Pandemics ; COVID-19/complications ; COVID-19/epidemiology ; Autonomic Nervous System Diseases/epidemiology ; Autonomic Nervous System Diseases/etiology ; Autonomic Nervous System ; Postural Orthostatic Tachycardia Syndrome/diagnosis ; Postural Orthostatic Tachycardia Syndrome/epidemiology
    Language English
    Publishing date 2023-11-10
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2057363-7
    ISSN 1534-6293 ; 1528-4042
    ISSN (online) 1534-6293
    ISSN 1528-4042
    DOI 10.1007/s11910-023-01320-z
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    Zs.A 5549: Show issues Location:
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  4. Article ; Online: Erratum to "Objective Hemodynamic Cardiovascular Autonomic Abnormalities in Post-Acute Sequelae of COVID-19" [Can J Cardiol 39 (2023):767-775].

    Hira, Rashmin / Baker, Jacquie R / Siddiqui, Tanya / Ranada, Shaun I / Soroush, Ateyeh / Karalasingham, Kavithra / Ahmad, Hyeqa / Mavai, Vibhuti / Valani, Luciano Martin Ayala / Ambreen, Sakina / Bourne, Kate M / Lloyd, Matthew G / Morillo, Carlos A / Sheldon, Robert S / Raj, Satish R

    The Canadian journal of cardiology

    2023  Volume 39, Issue 11, Page(s) 1732

    Language English
    Publishing date 2023-09-20
    Publishing country England
    Document type Published Erratum
    ZDB-ID 632813-1
    ISSN 1916-7075 ; 0828-282X
    ISSN (online) 1916-7075
    ISSN 0828-282X
    DOI 10.1016/j.cjca.2023.09.005
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    Zs.A 2150: Show issues Location:
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  5. Article ; Online: Objective Hemodynamic Cardiovascular Autonomic Abnormalities in Post-Acute Sequelae of COVID-19.

    Hira, Rashmin / Baker, Jacquie R / Siddiqui, Tanya / Ranada, Shaun I / Soroush, Ateyeh / Karalasingham, Kavithra / Ahmad, Hyeqa / Mavai, Vibhuti / Ayala Valani, Luciano Martin / Ambreen, Sakina / Bourne, Kate M / Lloyd, Matthew G / Morillo, Carlos A / Sheldon, Robert S / Raj, Satish R

    The Canadian journal of cardiology

    2022  Volume 39, Issue 6, Page(s) 767–775

    Abstract: Background: Many COVID-19 patients are left with symptoms several months after resolution of the acute illness; this syndrome is known as post-acute sequalae of COVID-19 (PASC). We aimed to determine the prevalence of objective hemodynamic ... ...

    Abstract Background: Many COVID-19 patients are left with symptoms several months after resolution of the acute illness; this syndrome is known as post-acute sequalae of COVID-19 (PASC). We aimed to determine the prevalence of objective hemodynamic cardiovascular autonomic abnormalities (CAA), explore sex differences, and assess the prevalence of CAA among hospitalized vs nonhospitalized patients with PASC.
    Methods: Patients with PASC (n = 70; female [F] = 56; 42 years of age; 95% confidence interval [CI], 40-48) completed standard autonomic tests, including an active stand test 399 days (338, 455) after their COVID-19 infection. Clinical autonomic abnormalities were evaluated.
    Results: Most patients with PASC met the criteria for at least 1 CAA (51; 73%; F = 43). The postural orthostatic tachycardia syndrome hemodynamic (POTS
    Conclusions: Patients with PASC have evidence of CAA, most commonly IOH
    MeSH term(s) Humans ; Male ; Female ; COVID-19/complications ; COVID-19/epidemiology ; Hemodynamics ; Cardiovascular System ; Hypotension, Orthostatic/diagnosis ; Hypotension, Orthostatic/epidemiology ; Hypotension, Orthostatic/etiology ; Autonomic Nervous System ; Disease Progression
    Language English
    Publishing date 2022-12-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 632813-1
    ISSN 1916-7075 ; 0828-282X
    ISSN (online) 1916-7075
    ISSN 0828-282X
    DOI 10.1016/j.cjca.2022.12.002
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  6. Article ; Online: Effect of age on the hemodynamic and sympathetic responses at the onset of isometric handgrip exercise.

    Lalande, Sophie / Sawicki, Carolyn P / Baker, Jacquie R / Shoemaker, J Kevin

    Journal of applied physiology (Bethesda, Md. : 1985)

    2013  Volume 116, Issue 2, Page(s) 222–227

    Abstract: Cardiac and peripheral vasomotor factors contribute to the rapid pressor response at the onset of isometric handgrip exercise. We tested the hypothesis that age enhances the sympathetic and vasoconstrictor response at the onset of isometric handgrip ... ...

    Abstract Cardiac and peripheral vasomotor factors contribute to the rapid pressor response at the onset of isometric handgrip exercise. We tested the hypothesis that age enhances the sympathetic and vasoconstrictor response at the onset of isometric handgrip exercise so that the pressor response is maintained, despite a diminished cardiac function. Twelve young and twelve older (24 ± 3 and 63 ± 8 yr) individuals performed 20-s isometric handgrip exercise at 30, 40, or 50% of maximal voluntary contraction force. Muscle sympathetic nerve activity (MSNA) was measured using microneurography. Mean arterial pressure (MAP) and cardiac output (Q) were assessed continuously by finger plethysmography and total peripheral resistance was calculated. MAP increased with the onset of handgrip; this increase was associated with handgrip intensity and was similar in both groups. Heart rate and Q increased with increasing handgrip intensity in both groups, but increases were greater in young vs. older individuals (age × handgrip intensity interaction, P < 0.05). MSNA burst frequency increased (P < 0.01), while MSNA burst incidence tended to increase (P = 0.06) with increasing handgrip intensity in both groups. The change in MSNA between baseline and handgrip, for both frequency and incidence, increased with increasing handgrip intensity for both groups. There was no effect of handgrip intensity or age on total peripheral resistance. The smaller heart rate and Q response during the first 20 s of handgrip exercise in older individuals was not accompanied by a greater sympathetic activation or vasoconstrictor response. However, increases in MAP were similar between groups, indicating that the pressor response at the onset of handgrip exercise is preserved with aging.
    MeSH term(s) Adult ; Age Factors ; Arterial Pressure/physiology ; Cardiac Output/physiology ; Exercise/physiology ; Female ; Hand Strength/physiology ; Heart/physiology ; Heart Rate/physiology ; Hemodynamics/physiology ; Humans ; Male ; Middle Aged ; Muscle, Skeletal/physiology ; Sympathetic Nervous System/physiology ; Vascular Resistance/physiology ; Vasoconstriction/physiology ; Young Adult
    Language English
    Publishing date 2013-12-12
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 219139-8
    ISSN 1522-1601 ; 0021-8987 ; 0161-7567 ; 8750-7587
    ISSN (online) 1522-1601
    ISSN 0021-8987 ; 0161-7567 ; 8750-7587
    DOI 10.1152/japplphysiol.01022.2013
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    Uc I Zs.249: Show issues Location:
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