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Article ; Online: Investigations on physiochemical and biomedical properties of Aloe vera - Sterculia gum copolymeric dressings impregnated with antibiotic-anesthetic drugs to enhance wound healing.

Sharma, Diwanshi / Sharma, Ashima / Bala, Ritu / Singh, Baljit

International journal of biological macromolecules

2024 Volume 267, Issue Pt 2, Page(s) 131363

Abstract: Recently, various innovative advancements have been made in carbohydrate research to design versatile materials for biomedical applications. The current research focuses on the development of copolymeric hydrogel wound dressings (HWD) using a combination ...

Abstract	Recently, various innovative advancements have been made in carbohydrate research to design versatile materials for biomedical applications. The current research focuses on the development of copolymeric hydrogel wound dressings (HWD) using a combination of aloe vera (AV) - sterculia gum (SG) - poly (vinylsulfonic acid) (VSA)-based with the aim to enhancing their efficacy in drug delivery (DD) applications. These hydrogel dressings were encapsulated with levofloxacin and lidocaine to address both microbial infection and pain. Copolymers were characterized by FESEM, SEM, EDS, AFM,
Language	English
Publishing date	2024-04-06
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	282732-3
ISSN	1879-0003 ; 0141-8130
ISSN (online)	1879-0003
ISSN	0141-8130
DOI	10.1016/j.ijbiomac.2024.131363
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Article ; Online: Clinical and ultrasonographic assessment of airway indices among non-pregnant, normotensive pregnant and pre-eclamptic patients: a prospective observational study.

Bala, R / Budhwar, D / Kumar, V / Singhal, S / Kaushik, P / Sharma, J

International journal of obstetric anesthesia

2023 Volume 54, Page(s) 103637

Abstract: Background: Prediction of a difficult airway is of paramount importance for an anaesthesiologist. Various anatomical and physiological factors contribute to a difficult airway in pregnant females, especially those with pre-eclampsia. The aim of the ... ...

Abstract	Background: Prediction of a difficult airway is of paramount importance for an anaesthesiologist. Various anatomical and physiological factors contribute to a difficult airway in pregnant females, especially those with pre-eclampsia. The aim of the study was to assess airway indices using both routinely used clinical methods and ultrasound. Methods: Fifty-five non-pregnant females, 55 normotensive pregnant females and 55 females with pre-eclampsia were included in this prospective study. Clinical airway assessment was the modified Mallampati score, thyromental distance, hyomental distance, hyomental distance ratio, chest circumference, neck circumference and chest-to-neck circumference ratio. Sonographic assessment included tongue width, tongue volume, anterior neck soft tissue thickness at the level of hyoid, epiglottis and vocal cords, subglottic diameter, ratio of pre-epiglottic space to anterior, posterior and midpoint of anterior and posterior vocal folds. Results: Several significant differences were observed between pregnant and non-pregnant females, with additional changes in pre-eclamptic females. These included clinical parameters such as the modified Mallampati score and sonographic measurements of tongue width, tongue volume, subglottic diameter, anterior neck soft tissue thickness at the level of hyoid, epiglottis and vocal cords, and the ratio of pre-epiglottic space to anterior, posterior and midpoint of anterior and posterior vocal folds. Conclusion: Routinely used clinical methods of airway assessment lack sensitivity and specificity. Ultrasound can visualise anatomical structures in the supraglottic and subglottic views and is encouraging as an airway assessment tool.
MeSH term(s)	Pregnancy ; Female ; Humans ; Prospective Studies ; Pre-Eclampsia/diagnostic imaging ; Tongue ; Hyoid Bone ; Intubation, Intratracheal/methods
Language	English
Publishing date	2023-02-01
Publishing country	Netherlands
Document type	Observational Study ; Journal Article
ZDB-ID	1086024-1
ISSN	1532-3374 ; 0959-289X
ISSN (online)	1532-3374
ISSN	0959-289X
DOI	10.1016/j.ijoa.2023.103637
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Article ; Online: Occurrence and behaviour of uranium in the groundwater and potential health risk associated in semi-arid region of Punjab, India

Bala, Ritu / Karanveer / Das, Debabrata

Groundwater for Sustainable Development. 2022 May, v. 17 p.100731-

2022

Abstract: Occurrence of uranium (U) in the groundwater of south-west Punjab is a matter of great concern due to the rise of contaminant levels at an alarming rate, its spatial and vertical variability and poor understanding of uranium mobility with depth. Present ... ...

Abstract	Occurrence of uranium (U) in the groundwater of south-west Punjab is a matter of great concern due to the rise of contaminant levels at an alarming rate, its spatial and vertical variability and poor understanding of uranium mobility with depth. Present study has been conducted to investigate the vertical extent of contamination and geochemical factors controlling U mobilization in the groundwater of semi-arid Punjab. Out of total 140 samples collected and analyzed, 76% samples have uranium levels greater than the chemical toxicity limit of World Health Organization (WHO, 30 μg.L⁻¹) and 34% samples have concentration higher than the radiological toxicity limit given by Atomic Energy Regulatory Board (AERB, 60 μg.L⁻¹). Water at shallow depth (<60 m) is found to be more contaminated than water at deeper depth (>60 m) and concentration lies in the range of 4.26–318.03 μg.L⁻¹. Spatial distribution graphs are used to identify the hotspots of contamination and concentration is higher in the flow direction of groundwater towards south-west. In both the aquifers, groundwater is alkaline and oxic in character with carbonate weathering as dominant hydrogeochemical process affecting chemical composition of water. Higher uranium concentration is seen in the oxidizing, alkaline and carbonate-rich water. Alkali earth metals (Na⁺ & K⁺) are also strongly correlated with the uranium in groundwater at both the levels. Use of environmental stable isotopes (δ¹⁸O & δ²H) shows the evaporation signature in both the aquifers. Health risk assessment is carried out and values higher than permissible limit give indication towards the health risk to the population exposed due to the consumption of uranium contaminated water from long time. This study provides a strong base for better understanding the source of uranium in the aquifer system of region and the results would be useful for further studies in quaternary alluvial aquifers of semi-arid regions.
Keywords	World Health Organization ; aquifers ; carbonates ; chemical composition ; evaporation ; groundwater ; health effects assessments ; hydrogeochemistry ; nuclear power ; risk ; semiarid zones ; sustainable development ; toxicity ; uranium ; India ; Stable isotope ; Human health risk ; Punjab ; AERB ; BDL ; Ca2+ ; Cl- ; cm ; EC ; HCO3- ; 2H ; K+ ; m ; mg.L-1 ; mg.kg-1 ; Mg2+ ; Na+ ; NO3- ; NW ; 18O ; ORP ; PO43- ; SO42- ; SW ; TDS ; U ; WHO ; μg.L−1
Language	English
Dates of publication	2022-05
Publishing place	Elsevier B.V.
Document type	Article ; Online
ISSN	2352-801X
DOI	10.1016/j.gsd.2022.100731
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Combating errors in quantum communication: an integrated approach.

Bala, Rajni / Asthana, Sooryansh / Ravishankar, V

Scientific reports

2023 Volume 13, Issue 1, Page(s) 2979

Abstract: Near-term quantum communication protocols suffer inevitably from channel noises, whose alleviation has been mostly attempted with resources such as multiparty entanglement or sophisticated experimental techniques. Generation of multiparty higher ... ...

Abstract	Near-term quantum communication protocols suffer inevitably from channel noises, whose alleviation has been mostly attempted with resources such as multiparty entanglement or sophisticated experimental techniques. Generation of multiparty higher dimensional entanglement is not easy. This calls for exploring realistic solutions which are implementable with current devices. Motivated particularly by the difficulty in generation of multiparty entangled states, in this paper, we have investigated error-free information transfer with minimal requirements. For this, we have proposed a new information encoding scheme for communication purposes. The encoding scheme is based on the fact that most noisy channels leave some quantities invariant. Armed with this fact, we encode information in these invariants. These invariants are functions of expectation values of operators. This information passes through the noisy channel unchanged. Pertinently, this approach is not in conflict with other existing error correction schemes. In fact, we have shown how standard quantum error-correcting codes emerge if suitable restrictions are imposed on the choices of logical basis states. As applications, for illustration, we propose a quantum key distribution protocol and an error-immune information transfer protocol.
Language	English
Publishing date	2023-02-20
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-30178-x
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Article: Alopecia Areata Treated with Homoeopathic Preparation of Phosphorus: Two Evidence-Based Case Reports

Srivastava, Amit / Ningthoujam, Gouri Devi / Bala, Renu

Homœopathic Links

2024 Volume 37, Issue 02, Page(s) 94–103

Abstract: Alopecia areata (AA) is a type of non-scarring, autoimmune hair loss on the scalp or body characterised by solitary or multiple bald patches. In modern medicine, treatment is mainly in the form of corticosteroids. Homoeopathy provides a better response ... ...

Abstract	Alopecia areata (AA) is a type of non-scarring, autoimmune hair loss on the scalp or body characterised by solitary or multiple bald patches. In modern medicine, treatment is mainly in the form of corticosteroids. Homoeopathy provides a better response by framing the totality and choosing the medicine based on symptom similarity. The presented case reports evaluated the utility of individualised homoeopathic treatment on AA with evidence-based assessment. The two cases were prescribed individualised homoeopathic medicine and followed for more than 1 year. The cases were assessed by Severity Alopecia Tool (SALT) score, Measure Yourself Medical Outcome Profile 2 (MYMOP2) and periodic photographic evidence. Modified Naranjo Criteria for Homoeopathy (MONARCH) was used to assess the clinical outcome's causal attribution to the prescribed homoeopathic medicine. Both patients were given Phosphorus in centesimal potency resulting in a complete cure with a full growth of hair and without further relapse of symptoms. SALT score reduced from 24.04 to 0% in case 1 and 8.4 to 0% in case 2 after 18 months of treatment. MYMOP2 profile score declined from 3.5 to 0 in case 1 and 5.5 to 0 in case 2. The physician assessed the MONARCH score as +09 and +10 for cases 1 and 2, signifying strong causal attribution to Phosphorus prescribed in both cases. Individualised homoeopathic treatment caused improvement in AA along with general well-being. Systematic research with a larger sample size would be required to confirm observations of these two cases.
Keywords	alopecia areata ; homoeopathy ; individualised medicine ; MYMOP2 ; Modified Naranjo criteria ; SALT score ; Phosphorus
Language	English
Publishing date	2024-03-21
Publisher	Thieme Medical and Scientific Publishers Pvt. Ltd.
Publishing place	Stuttgart ; New York
Document type	Article
ZDB-ID	1199312-1
ISSN	1860-3149 ; 1019-2050
ISSN (online)	1860-3149
ISSN	1019-2050
DOI	10.1055/s-0043-1772489
Database	Thieme publisher's database

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Article ; Online: A prospective randomized study to evaluate the efficacy of pressure support ventilation with and without positive end expiratory pressure for preoxygenation in adult patients.

Taxak, Susheela / Gupta, Mohini / Bala, Renu / Govil, Vasudha / Lallar, Anushmita

Medical gas research

2023 Volume 13, Issue 4, Page(s) 187–191

Abstract: A primary concern for anesthesiologists is the maintenance of oxygenation during general anesthesia. Extending the safe apnea time, which is the time from the onset of apnea until the oxygen saturation concentration reaches 90% or less, increases the ... ...

Abstract	A primary concern for anesthesiologists is the maintenance of oxygenation during general anesthesia. Extending the safe apnea time, which is the time from the onset of apnea until the oxygen saturation concentration reaches 90% or less, increases the margin of safety with tracheal intubation. Preoxygenation before anesthetic induction has been a widely accepted manoeuver to increase oxygen reserves and hence delay the onset of arterial desaturation during apnea. This study aimed to evaluate the efficacy of pressure support ventilation with/without positive end-expiratory pressure (PEEP) for preoxygenation in adult patients. A total of 132 patients, aged 20 to 50 years, scheduled for elective surgery under general anesthesia, requiring endotracheal intubation, were included and randomly divided into three groups (n = 44 per group): spontaneous ventilation (SV), pressure support ventilation without PEEP (PS), and pressure support ventilation with PEEP (PEEP) groups. In the SV group, the patients breathed spontaneously without any support using a face mask; in the PS group, the patients breathed spontaneously with the inspiratory pressure support of 12 cm H
MeSH term(s)	Humans ; Adult ; Apnea/therapy ; Prospective Studies ; Positive-Pressure Respiration ; Anesthesia, General ; Oxygen
Chemical Substances	Oxygen (S88TT14065)
Language	English
Publishing date	2023-04-19
Publishing country	Australia
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	2616230-1
ISSN	2045-9912 ; 2045-9912
ISSN (online)	2045-9912
ISSN	2045-9912
DOI	10.4103/2045-9912.372665
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Article ; Online: Lanthanum nanoparticle (La

Singh, Asha / Arora, Dinesh / Bala, Renu / Khokhar, Anil / Kumar, Sunil

Environmental science and pollution research international

2023 Volume 30, Issue 48, Page(s) 105415–105428

Abstract: Nanocomposite adsorbents for wastewater treatment gained popularity in recent times. In the present study, nanoparticles prepared from lanthanum have been loaded on the powdered form of aquatic plants Salvinia molesta (S. molesta) and Typha latifolia (T. ...

Abstract	Nanocomposite adsorbents for wastewater treatment gained popularity in recent times. In the present study, nanoparticles prepared from lanthanum have been loaded on the powdered form of aquatic plants Salvinia molesta (S. molesta) and Typha latifolia (T. latifolia). These new adsorbents were NPS (nanoparticle-loaded S. molesta) and NPT (nanoparticle-loaded T. latifolia). The batch study was carried out to assess the effect of several factors on the adsorption of Cr(VI) by novel adsorbents NPS and NPT. XRD, SEM, FTIR, EDX, and Zeta potential were used for the characterization of nanoparticles formed and novel adsorbents. The maximal adsorption was noticed by both adsorbents at pH 1, 20 ppm of initial metal concentration, and 1 h of contact period with 150 rpm at 25 ℃. The adsorbent dose of 60 mg and 80 mg was observed as the equilibrium dose for NPS and NPT, respectively. The maximum adsorption capacity observed was 27.18 mg/g for NPS and 19.85 mg/g for NPT. Freundlich isotherm was better fitted for both adsorbents. Pseudo-second-order kinetics depicts the better mechanism of adsorption with R
MeSH term(s)	Lanthanum ; Chromium/chemistry ; Thermodynamics ; Water Purification ; Kinetics ; Nanoparticles ; Adsorption ; Hydrogen-Ion Concentration ; Water Pollutants, Chemical/analysis
Chemical Substances	chromium hexavalent ion (18540-29-9) ; lanthanum oxide (4QI5EL790W) ; Lanthanum (6I3K30563S) ; Chromium (0R0008Q3JB) ; Water Pollutants, Chemical
Language	English
Publishing date	2023-09-16
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-023-29834-6
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Article: Practice, prescription habits, experience and perception of Indian homeopathic practitioners in treatment of diabetes mellitus: An online observational study.

Varanasi, Roja / Srivastava, Amit / Kumar Rt, Shaji / Bala, Renu

Journal of Ayurveda and integrative medicine

2023 Volume 14, Issue 5, Page(s) 100787

Abstract: Background: Studies have shown homoeopathy to effectively control blood sugar levels and improve quality of life (QOL), though a standard treatment protocol is required.: Objective: This study intended to assess the homoeopathic practice, ... ...

Abstract	Background: Studies have shown homoeopathy to effectively control blood sugar levels and improve quality of life (QOL), though a standard treatment protocol is required. Objective: This study intended to assess the homoeopathic practice, prescription habits, experience, and perception of Indian Homeopathic Practitioners (HPs) in treating DM. Methodology: A web-based cross-sectional with a snowball sampling method was conducted between 30th July 2021 and 18th August 2021. A questionnaire to record clinical attributes of Indian HPs in the management of DM was formed after the consensus of the subject experts and pilot testing for feasibility. Results: Participants were 513 HPs with mean age [Standard Deviation (SD)] of 40.44 years (11.16) and a mean duration of the homoeopathic medical practice of 14.67 years [95% Confidence Interval (CI) = 13.71-15.63]. The majority of HPs made classical homoeopathic prescription (201, 39.2%) though the success in the management of DM was better among HPs who prescribed more than one potentized medicine [vs classical prescription, Odds Ratio (OR) = 2.34, p = 0.032]. As perceived by the HPs, homoeopathic treatment resulted in a major improvement in QOL of the diabetic patients (418, 81.5%) with very few adverse effect (100, 19.5%). The blood sugar level was controlled better when homoeopathy was given alongside conventional medicine (348, 67.8%). Conclusion: The clinical experience of HPs in this study has shown that homoeopathic treatment can benefit DM patients in preventing complications and improving QOL. It further reported that homoeopathy can be an important adjuvant to conventional treatment in managing DM.
Language	English
Publishing date	2023-09-24
Publishing country	United States
Document type	Journal Article
ISSN	0975-9476
ISSN	0975-9476
DOI	10.1016/j.jaim.2023.100787
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Article ; Online: The preconception health status of nongravid women aged 18 to 45 years in Arima, Trinidad: a cross-sectional study.

Bala, Ria / Maharaj, Rohan G / Boppana, Leela Krishna Teja / Teelucksingh, Surujpal

BMC pregnancy and childbirth

2023 Volume 23, Issue 1, Page(s) 720

Abstract: Background: Preconception care (PCC) is the term used for activities and interventions designed to address and prevent problems related to pregnancy, the neonatal period and childhood. This study assessed maternal health status prior to conception in ... ...

Abstract	Background: Preconception care (PCC) is the term used for activities and interventions designed to address and prevent problems related to pregnancy, the neonatal period and childhood. This study assessed maternal health status prior to conception in Trinidad by means of a screening tool, physical measurements, and laboratory samples. Methods: A cross-sectional study was conducted among women aged 18-45 years at a primary care centre in Arima, Trinidad. A de novo PCC screening tool was used to assess 13 domains of high-risk pregnancy in participants. These domains included dietary details, gynaecological and obstetric histories, and genetic and vaccination histories, among others. Blood pressure, weight, height, and waist circumference were recorded, and a capillary blood sample was used to determine random blood glucose and HbA1c levels. All data were coded and entered into SPSS ver. 21. Results: A total of 400 nongravid participants were recruited, of whom 366 were included in the final analysis. Most (96.7%) had one or more risk factors for adverse pregnancy outcomes. These included overweight (27%), obesity (35%), central obesity (69.4%), and impaired glucose tolerance/diabetes mellitus (IGT/DM) (26.2%). Additionally, a sedentary lifestyle and diet high in processed food/fats were self-reported by 74.9% and 88.8% of participants, respectively. Only 13.1% had planned to conceive, and of those who had no immediate plans to conceive, 76.4% were currently sexually active, and many (60.7%) did not use birth control techniques. More than half (57.1%) had never had a pap smear. On the other hand, 86.3% knew their HIV status. Self-reported percentages for vaccination were as follows: MMR (100%), tetanus (17.5%), hepatitis B (11.5%) and influenza (2.7%). The majority (82.8%) of participants had not visited the dentist in the past year, with 35.9% of these individuals reporting symptoms of periodontitis. Segments of the population had multiple risk factors; for example, 23.7% of participants were overweight or obese and had an elevated HbA1c level. Conclusions: Unexpectedly, most participants had a risk factor for an adverse pregnancy outcome, and many had multiple risk factors. There is a strong case for enhanced preconception care for women in Trinidad.
MeSH term(s)	Adult ; Middle Aged ; Young Adult ; Cross-Sectional Studies ; Glycated Hemoglobin ; Obesity/epidemiology ; Overweight ; Preconception Care ; Trinidad and Tobago/epidemiology ; Humans ; Female
Chemical Substances	Glycated Hemoglobin
Language	English
Publishing date	2023-10-10
Publishing country	England
Document type	Journal Article
ZDB-ID	2059869-5
ISSN	1471-2393 ; 1471-2393
ISSN (online)	1471-2393
ISSN	1471-2393
DOI	10.1186/s12884-023-06017-2
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Article ; Online: Purification and characterization of a high molecular weight serine protease from Microbacterium paraoxydans sp. SKS10.

Saggu, Sandeep Kaur / Bala, Renu / Hora, Rachna / Mishra, Prakash Chandra

Biotechnology and applied biochemistry

2023 Volume 70, Issue 5, Page(s) 1741–1753

Abstract: Alkaline proteases from microbial sources have been found suitable for diverse industrial applications, with serine proteases being the most common enzymes used in the detergent industry. In the present study, we have purified and characterized an ... ...

Abstract	Alkaline proteases from microbial sources have been found suitable for diverse industrial applications, with serine proteases being the most common enzymes used in the detergent industry. In the present study, we have purified and characterized an extracellular alkaline serine protease from Microbacterium paraoxydans sp. SKS10. The protease was purified using ammonium sulfate precipitation followed by different chromatography techniques (fold purification 6.919). K
MeSH term(s)	Serine Proteases/chemistry ; Detergents/chemistry ; Molecular Weight ; Endopeptidases/chemistry ; Endopeptidases/metabolism ; Bacterial Proteins/chemistry ; Hydrogen-Ion Concentration ; Enzyme Stability ; Temperature
Chemical Substances	Serine Proteases (EC 3.4.-) ; Detergents ; Endopeptidases (EC 3.4.-) ; Bacterial Proteins
Language	English
Publishing date	2023-05-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	883433-7
ISSN	1470-8744 ; 0885-4513
ISSN (online)	1470-8744
ISSN	0885-4513
DOI	10.1002/bab.2472
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