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  1. Article ; Online: Searching for phase transitions in the dark.

    Baldini, Edoardo

    Nature

    2023  Volume 622, Issue 7983, Page(s) 464–465

    Language English
    Publishing date 2023-10-18
    Publishing country England
    Document type News
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/d41586-023-03148-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 26: Show issues Location:
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  2. Article ; Online: Estimating the Environmental Impact of Green IoT Deployments.

    Baldini, Edoardo / Chessa, Stefano / Brogi, Antonio

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 3

    Abstract: The Internet of Things (IoT) is demonstrating its huge innovation potential, but at the same time, its spread can induce one of highest environmental impacts caused by the IoT industry. This concern has motivated the rise of a new research area aimed at ... ...

    Abstract The Internet of Things (IoT) is demonstrating its huge innovation potential, but at the same time, its spread can induce one of highest environmental impacts caused by the IoT industry. This concern has motivated the rise of a new research area aimed at devising green IoT deployments. Our work falls in this research area by contributing to addressing the problem of assessing the environmental impact of IoT deployments. Specifically, we propose a methodology based on an analytical model to assess the environmental impact of an outdoor IoT deployment powered by solar energy harvesting. The model inputs the specification of the IoT devices that constitute the deployment in terms of the battery, solar panel and electronic components, and it outputs the energy required for the entire life-cycle of the deployment and the waste generated by its disposal. Given an existing IoT deployment, the models also determine a functionally equivalent baseline green solution, which is an ideal configuration with a lower environmental impact than the original solution. We validated the proposed methodology by means of the analysis of a case study conducted over an existing IoT deployment developed within the European project RESCATAME. In particular, by means of the model, we evaluate the impact of the RESCATAME system and assess its impact with respect to its baseline. In a scenario with a 30-year lifespan, the model estimates for the system more than 3 times the energy required by its baseline green solution and a waste for a volume 15 times greater. We also show how the impact of the baseline increases when assuming deployments in locations at increasing latitudes. Finally, the article presents an implementation of the proposed methodology as a web service that is publicly available.
    Language English
    Publishing date 2023-01-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23031537
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Retroperitoneal Sarcoma: Setting the Stage for Treatment Strategies Tailored to Histologic Subtype and Other Patient and Tumor Factors.

    Baldini, Elizabeth

    International journal of radiation oncology, biology, physics

    2017  Volume 99, Issue 2, Page(s) 292–295

    Language English
    Publishing date 2017-10-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 197614-x
    ISSN 1879-355X ; 0360-3016
    ISSN (online) 1879-355X
    ISSN 0360-3016
    DOI 10.1016/j.ijrobp.2017.05.021
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1218: Show issues Location:
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  4. Article ; Online: Chemo-radiotherapy integration in unresectable locally advanced non-small-cell lung cancer: a review.

    Baldini, E / Tibaldi, C / Delli Paoli, C

    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico

    2020  Volume 22, Issue 10, Page(s) 1681–1686

    Abstract: Approximately one-third of all non-small-cell lung cancer (NSCLC) are locally-advanced at diagnosis, and 15-17% of these tumors are unresectable at presentation. Definitive chemo-radiotherapy (CRT) represents the standard therapeutic approach. However, ... ...

    Abstract Approximately one-third of all non-small-cell lung cancer (NSCLC) are locally-advanced at diagnosis, and 15-17% of these tumors are unresectable at presentation. Definitive chemo-radiotherapy (CRT) represents the standard therapeutic approach. However, the literature has shown that only 15% of patients are alive at 5 years and this percentage has remained unchanged despite various attempts of improvement. The recent introduction of immunotherapy has not only strongly changed the clinical scenario but has also drawn attention to a stage of disease apparently forgotten for decades. Stage III NSCLC can represent an interesting setting for the combined use of chemo-radiation and immunotherapy, due to the potential synergistic effect between radiation and immune checkpoint inhibitors. We reviewed the available literature in order to report the state of art of stage III NSCLC, by focusing on trials that evaluate different combinations of CRT and new drugs of PD-1/PD-L1 axis, and anti-CTLA-4. The future goal in the management of unresectable stage III NSCLC will be the optimal patients' selection combined with the use of individualized immuno/chemotherapies that could potentially improve clinical outcomes.
    MeSH term(s) Carcinoma, Non-Small-Cell Lung/therapy ; Chemoradiotherapy/methods ; Clinical Trials as Topic ; Humans ; Immunotherapy ; Lung Neoplasms/therapy
    Language English
    Publishing date 2020-03-04
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 2397359-6
    ISSN 1699-3055 ; 1699-048X
    ISSN (online) 1699-3055
    ISSN 1699-048X
    DOI 10.1007/s12094-020-02326-6
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6644: Show issues Location:
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  5. Article ; Online: A necrotising fasciitis: case report.

    Cantarella, S / Casamassima, A / Bussone, Dott M / Baldini, E / Kersik, A / Boccia, O / Gianotti, C

    Journal of ultrasound

    2023  Volume 26, Issue 1, Page(s) 147–150

    Abstract: Necrotizing fasciitis is one of the most common soft tissue infections, with a high risk of major amputation and a mortality ranging from 6 to 33% which has not changed in the past 20 years. Early surgical resection of necrotic tissue plays a key role in ...

    Abstract Necrotizing fasciitis is one of the most common soft tissue infections, with a high risk of major amputation and a mortality ranging from 6 to 33% which has not changed in the past 20 years. Early surgical resection of necrotic tissue plays a key role in determining the prognosis. Nawijn et al. identified an optimal 6 hours window from presentation to surgery. Symptoms of necrotizing fasciitis mimic those of common skin infections, such as erysipelas and cellulitis, making rapid surgical management difficult. In this context, the aid of point-of-care-ultrasound is a valuable tool for early diagnosis, detecting the presence of subcutaneous thickening, gas and perifascial liquid. Other characteristic ultrasound findings include the "cobblestone" appearance of the subcutaneous soft tissues and reverberation artifacts due to hyperechoic outbreaks, defined as "snow globes" due to the presence of heterogeneous swirling material, and "dirty shadowing" due to the foggy shadow created by the gas.
    MeSH term(s) Humans ; Fasciitis, Necrotizing/diagnostic imaging ; Fasciitis, Necrotizing/surgery ; Prognosis ; Necrosis ; Point-of-Care Testing ; Soft Tissue Infections/diagnosis
    Language English
    Publishing date 2023-01-06
    Publishing country Italy
    Document type Case Reports ; Journal Article
    ZDB-ID 2365426-0
    ISSN 1876-7931 ; 1971-3495
    ISSN (online) 1876-7931
    ISSN 1971-3495
    DOI 10.1007/s40477-022-00717-9
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  6. Article ; Online: Magnetically propagating Hund's exciton in van der Waals antiferromagnet NiPS

    He, W / Shen, Y / Wohlfeld, K / Sears, J / Li, J / Pelliciari, J / Walicki, M / Johnston, S / Baldini, E / Bisogni, V / Mitrano, M / Dean, M P M

    Nature communications

    2024  Volume 15, Issue 1, Page(s) 3496

    Abstract: Magnetic van der Waals (vdW) materials have opened new frontiers for realizing novel many-body phenomena. Recently ... ...

    Abstract Magnetic van der Waals (vdW) materials have opened new frontiers for realizing novel many-body phenomena. Recently NiPS
    Language English
    Publishing date 2024-04-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-024-47852-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: A reply to "Immune related adverse events and response to immunotherapy: focus on corticosteroids."

    Baldini, Editta / Tibaldi, Carmelo

    Lung cancer (Amsterdam, Netherlands)

    2020  Volume 145, Page(s) 226

    MeSH term(s) Adrenal Cortex Hormones ; Humans ; Immunotherapy ; Italy ; Lung Neoplasms ; Nivolumab
    Chemical Substances Adrenal Cortex Hormones ; Nivolumab (31YO63LBSN)
    Language English
    Publishing date 2020-04-24
    Publishing country Ireland
    Document type Letter ; Comment
    ZDB-ID 632771-0
    ISSN 1872-8332 ; 0169-5002
    ISSN (online) 1872-8332
    ISSN 0169-5002
    DOI 10.1016/j.lungcan.2020.04.018
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2135: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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    Zs.MO 423: Show issues

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  8. Article ; Online: Elucidating Piezoelectricity and Strain in Monolayer MoS

    De Palma, Alex C / Peng, Xinyue / Arash, Saba / Gao, Frank Y / Baldini, Edoardo / Li, Xiaoqin / Yu, Edward T

    Nano letters

    2024  Volume 24, Issue 6, Page(s) 1835–1842

    Abstract: Strain engineering modifies the optical and electronic properties of atomically thin transition metal dichalcogenides. Highly inhomogeneous strain distributions in two-dimensional materials can be easily realized, enabling control of properties on the ... ...

    Abstract Strain engineering modifies the optical and electronic properties of atomically thin transition metal dichalcogenides. Highly inhomogeneous strain distributions in two-dimensional materials can be easily realized, enabling control of properties on the nanoscale; however, methods for probing strain on the nanoscale remain challenging. In this work, we characterize inhomogeneously strained monolayer MoS
    Language English
    Publishing date 2024-02-05
    Publishing country United States
    Document type Journal Article
    ISSN 1530-6992
    ISSN (online) 1530-6992
    DOI 10.1021/acs.nanolett.3c03100
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  9. Article: Bowel obstruction in obturator hernia: A challenging diagnosis.

    Conti, L / Baldini, E / Capelli, P / Capelli, C

    International journal of surgery case reports

    2017  Volume 42, Page(s) 154–157

    Abstract: Introduction: The obturator hernia is a rare pelvic hernia that often comes in the shape of bowel obstruction caused by the presence of an intestinal segment, more often ileum, passing trough the obturator foramen of the pelvic wall (Fig. 1). This type ... ...

    Abstract Introduction: The obturator hernia is a rare pelvic hernia that often comes in the shape of bowel obstruction caused by the presence of an intestinal segment, more often ileum, passing trough the obturator foramen of the pelvic wall (Fig. 1). This type of hernia accounts for 0.5-1.4% of all hernias.
    Case presentation: We report the clinical case of a 84-year-old woman with no previous surgical interventions, who went to the emergency room complaining of vomit and nausea, bowels closed to gas and stool, which she had experienced for three previous days. Routine blood test showed impaired renal function and hydrohelectrolyte imbalance. A CT scan revealed a right ileal, strangulated obturator hernia. The patient underwent an emergency surgical intervention with laparoscopic trans-abdominal peritoneal approach (TAP): after the reduction of the herniated segment, a primary suturing of the parietal defect was performed without ileal resection.
    Discussion: Because of the non-specific symptoms the diagnosis of this kind of hernia is often unclear; female are 6-9 times more likely than men to be subject to the aforementioned pathology, mostly occurring in multiparous, emaciated, elderly woman so it is also called "the little old lady's hernia". Risk factors are loss of weight, chronic pulmonary disease and ascites which increase the abdominal pressure. An unfrequent presenting sign is a palpable mass, or the Howship-Romberg sign- a pain radiating from the inner tigh and knee - but it could be misleading when confused with symptoms of gonarthrosis or lumbar vertebral disc pathology. CT scan has superior sensitivity and accuracy with respect to other radiological exams to assess the presence of an obturator hernia.
    Conclusion: Obturator hernia is a rare type of hernia due to his diagnosis, which is often unclear; a prompt suspect based for the non-specific symptoms is crucial for the diagnosis. Surgical management depends on early diagnosis and it is the only possible treatment for this pathology.
    Language English
    Publishing date 2017-12-07
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2210-2612
    ISSN 2210-2612
    DOI 10.1016/j.ijscr.2017.12.003
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  10. Article: Ribociclib Plus Letrozole in Italian Male Patients with Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer: Case Studies of Phase 3b CompLEEment-1 Trial.

    Caputo, Roberta / Fabi, Alessandra / Romagnoli, Emanuela / Baldini, Editta / Grasso, Donatella / Fenderico, Nicola / Michelotti, Andrea

    Breast cancer (Dove Medical Press)

    2022  Volume 14, Page(s) 351–362

    Abstract: Abstract: Male breast cancer (BC) is rare, globally constituting only 0.5-1% of all patients with BC. In Italy, more than 2000 new male BC cases were registered between 2000 and 2014. The survival rate was lower in males than in females. Delayed ... ...

    Abstract Abstract: Male breast cancer (BC) is rare, globally constituting only 0.5-1% of all patients with BC. In Italy, more than 2000 new male BC cases were registered between 2000 and 2014. The survival rate was lower in males than in females. Delayed diagnosis may be the reason for poorer outcome observed in male BC patients compared with female patients. Due to lack of substantial evidence and low availability of published data on male BC, the current treatment recommendations are based on evidence derived from trials on female patients. In Italy, most of the male BC patients are estrogen and progesterone receptor-positive. Targeted therapy in combination with endocrine therapy provides a clinically meaningful outcome in patients with hormone receptor-positive (HR-positive), human epidermal growth factor receptor 2-negative (HER2-negative) advanced BC. CompLEEment-1 is a single-arm, open-label, multicenter, phase 3b trial investigating the safety and efficacy of a CDK4/6 inhibitor, ribociclib, in combination with letrozole in men and women. Herein, we report the results from a retrospective analysis of five Italian male patients who completed the core phase. In this case series, the combination of ribociclib and letrozole was well tolerated and appeared to be effective in the male cohort with HR-positive, HER2-negative advanced BC in Italy. CompLEEment-1 trial representative of a real-world setting would add value by supporting the existing efficacy and safety profile of ribociclib in combination with letrozole in male patients with HR-positive, HER2-negative advanced BC.
    Clinicaltrialsgov registration number: NCT02941926.
    Language English
    Publishing date 2022-10-18
    Publishing country New Zealand
    Document type Case Reports
    ZDB-ID 2520722-2
    ISSN 1179-1314
    ISSN 1179-1314
    DOI 10.2147/BCTT.S376902
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