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Article ; Online: Dental zirconia microwave-sintering followed by rapid cooling protocol.

Barchetta, Nayara Fernanda / Arata Found, Anelyse / Yoshito, Walter Kenji / Ussui, Valter / Lazar, Dolores Ribeiro Ricci / Balducci, Ivan / Butler, Sheila / Saavedra, Guilherme de Siqueira Ferreira Anzaloni

Journal of the mechanical behavior of biomedical materials

2023 Volume 151, Page(s) 106351

Abstract: Objectives: This study aimed to evaluate the effect of microwave sintering temperature and cooling rate (MS) on 3Y-TZP ceramics and its influence on the ceramic microstructure and mechanical properties. Specifically, to optimize the sintering process, ... ...

Abstract	Objectives: This study aimed to evaluate the effect of microwave sintering temperature and cooling rate (MS) on 3Y-TZP ceramics and its influence on the ceramic microstructure and mechanical properties. Specifically, to optimize the sintering process, reducing the total sintering time compared to conventional sintering. Materials and methods: Eighty-four pre-sintered Y-TZP discs (Vipi block Zirconn, VIPI) (ISO 6872) were divided into seven groups (n = 12) according to the sintering conditions: conventional sintering (CS) at 1530 °C for 120 min and microwave sintering at 1400 °C (MS1400) and 1450 °C (MS1450) for 15 min followed by different cooling conditions: rapid cooling (RC), cooling at 400 °C (C400) and 25 °C (C25). The specimens were submitted to apparent density measurements, X-ray diffraction analysis (XRD), scanning electron microscopy, and biaxial flexural strength test. Data was statistically analyzed through two-way ANOVA, Tukey, Sidak, Dunnett and Weibull (α = 0.05). Results: All MS1400 groups presented lower density values than the CS and MS1450 groups. Two-way ANOVA revealed that the MS temperature and cooling rate affected the biaxial flexural strength of the Y-TZP (p < 0.01). Group MS1400RC presented lower biaxial flexural strength values (681.9 MPa) than MS1450RC (824.7 MPa). The cooling rate did not statistically decrease the biaxial strength among the groups submitted to microwave sintering at 1450 °C. XRD analysis showed that the sintering and cooling temperature did not induce tetragonal to monoclinic phase transformation. Conclusions: Microwave sintering at 1450 °C for 15 min followed by rapid cooling can be a viable fast alternative protocol for Y-TZP sintering, compared with the conventional sintering, reducing the total sintering time by 75% and reducing the energy used for the sintering process without affecting the Y-TZP biaxial flexural strength and relative density compared to the conventional sintering. Moreover, the microwave technique promoted smaller grains and did not induce monoclinic phase formation.
MeSH term(s)	Materials Testing ; Surface Properties ; Microwaves ; Yttrium/chemistry ; Zirconium/chemistry ; Ceramics/chemistry ; Dental Materials
Chemical Substances	zirconium oxide (S38N85C5G0) ; Yttrium (58784XQC3Y) ; Zirconium (C6V6S92N3C) ; Dental Materials
Language	English
Publishing date	2023-12-26
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2378381-3
ISSN	1878-0180 ; 1751-6161
ISSN (online)	1878-0180
ISSN	1751-6161
DOI	10.1016/j.jmbbm.2023.106351
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Article ; Online: Edentulism in Brazil: trends, projections and expectations until 2040.

Cardoso, Mayra / Balducci, Ivan / Telles, Daniel de Moraes / Lourenço, Eduardo José Veras / Nogueira Júnior, Lafayette

Ciencia & saude coletiva

2016 Volume 21, Issue 4, Page(s) 1239–1246

Abstract: The aim of this study was to examine the edentulism rates in Brazil and make projections for the next years. Data were collected from three national oral health surveys. The percentage of edentulous jaws was calculated. Projections were made for the ... ...

Abstract	The aim of this study was to examine the edentulism rates in Brazil and make projections for the next years. Data were collected from three national oral health surveys. The percentage of edentulous jaws was calculated. Projections were made for the years 2020, 2030 and 2040, assuming that edentulism follows a logistic function. Population projections were also performed. Annual change in proportion of edentulous jaws was -0.04% for teenagers, -0.96% for adults and 0.76% for the elderly. By 2040, edentulous jaws will be virtually zero among teenagers, 1.77% among adults and 85.96% among the elderly. Teenagers will slightly decrease in number; adults will increase and subsequently decrease; the elderly will continue to increase. In teenagers and adults, the number of edentulous jaws will decrease, being approximately 616,000 in 2040. In the elderly, it will increase alarmingly, reaching over 64 million in 2040. Edentulism is declining in Brazil among teenagers and middle-aged adults, but is still increasing and will continue to increase for the next decades among the elderly.
MeSH term(s)	Adolescent ; Adult ; Aged ; Brazil/epidemiology ; Dental Health Surveys ; Female ; Forecasting ; Humans ; Male ; Middle Aged ; Mouth, Edentulous/epidemiology ; Young Adult
Language	English
Publishing date	2016-04
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	2078799-6
ISSN	1678-4561 ; 1413-8123
ISSN (online)	1678-4561
ISSN	1413-8123
DOI	10.1590/1413-81232015214.13672015
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Article ; Online: Evaluation of the Accuracy of Conventional and Digital Impression Techniques for Implant Restorations.

Moura, Renata Vasconcellos / Kojima, Alberto Noriyuki / Saraceni, Cintia Helena Coury / Bassolli, Lucas / Balducci, Ivan / Özcan, Mutlu / Mesquita, Alfredo Mikail Melo

Journal of prosthodontics : official journal of the American College of Prosthodontists

2018 Volume 28, Issue 2, Page(s) e530–e535

Abstract: Purpose: The increased use of CAD systems can generate doubt about the accuracy of digital impressions for angulated implants. The aim of this study was to evaluate the accuracy of different impression techniques, two conventional and one digital, for ... ...

Abstract	Purpose: The increased use of CAD systems can generate doubt about the accuracy of digital impressions for angulated implants. The aim of this study was to evaluate the accuracy of different impression techniques, two conventional and one digital, for implants with and without angulation. Materials and methods: We used a polyurethane cast that simulates the human maxilla according to ASTM F1839, and 6 tapered implants were installed with external hexagonal connections to simulate tooth positions 17, 15, 12, 23, 25, and 27. Implants 17 and 23 were placed with 15° of mesial angulation and distal angulation, respectively. Mini cone abutments were installed on these implants with a metal strap 1 mm in height. Conventional and digital impression procedures were performed on the maxillary master cast, and the implants were separated into 6 groups based on the technique used and measurement type: G1 - control, G2 - digital impression, G3 - conventional impression with an open tray, G4 - conventional impression with a closed tray, G5 - conventional impression with an open tray and a digital impression, and G6 - conventional impression with a closed tray and a digital impression. A statistical analysis was performed using two-way repeated measures ANOVA to compare the groups, and a Kruskal-Wallis test was conducted to analyze the accuracy of the techniques. Results: No significant difference in the accuracy of the techniques was observed between the groups. Therefore, no differences were found among the conventional impression and the combination of conventional and digital impressions, and the angulation of the implants did not affect the accuracy of the techniques. Conclusions: All of the techniques exhibited trueness and had acceptable precision. The variation of the angle of the implants did not affect the accuracy of the techniques.
MeSH term(s)	Dental Impression Materials ; Dental Impression Technique ; Dental Models ; Dental Prosthesis, Implant-Supported ; Humans ; In Vitro Techniques ; Maxilla
Chemical Substances	Dental Impression Materials
Language	English
Publishing date	2018-05-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	1197213-0
ISSN	1532-849X ; 1059-941X
ISSN (online)	1532-849X
ISSN	1059-941X
DOI	10.1111/jopr.12799
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Article ; Online: Oral lichen planus

Guimarães Cabral Luiz / Balducci Ivan / Almeida Janete / Oliveira Alves Mônica

BMC Research Notes, Vol 3, Iss 1, p

A retrospective study of 110 Brazilian patients

2010 Volume 157

Abstract: Abstract Background Oral lichen planus (OLP) is a chronic autoimmune disease characterized by multiple clinical presentations and a relatively high prevalence in the population. This retrospective patient record study investigated the profile of OLP in a ...

Abstract	Abstract Background Oral lichen planus (OLP) is a chronic autoimmune disease characterized by multiple clinical presentations and a relatively high prevalence in the population. This retrospective patient record study investigated the profile of OLP in a group of Brazilian patients seen between 1989 and 2009. Findings The clinical records were analyzed and data such as gender, age, race, clinical presentation of OLP, site affected, presence of symptoms and extraoral manifestations of the disease, smoking habit, and consumption of alcoholic beverages were obtained. Among the 1822 records of patients with oral mucosal lesions, OLP was identified in 6.03%. Of these, 76.36% were females, with a mean age of 54 years, and 85% were whites. The reticular form was the most frequent (81.81%). Extraoral lesions were observed in 32.72% of the patients and painful symptoms were reported by 50.90%. The cheek mucosa was the site most affected (92.72%) and multiple oral lesions were observed in 77.27% of the patients. Among patients with OLP, 18.18% reported a smoking habit and 29.09% the consumption of alcoholic beverages. Conclusions This retrospective study showed a relatively high prevalence of OLP in the population studied, with a predominance of the disease among middle-aged white women and bilateral involvement of the cheek mucosa. Reticular lesions were the most frequent, followed by the erosive form which is mainly associated with painful symptoms. No relationship with tobacco or alcohol consumption was observed.
Keywords	Medicine ; R ; Biology (General) ; QH301-705.5 ; Science (General) ; Q1-390
Subject code	610
Language	English
Publishing date	2010-06-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
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Article ; Online: Oral lichen planus: a histopathological study.

Alves, Mônica G Oliveira / Balducci, Ivan / Carvalho, Yasmin Rodarte / Nunes, Fábio D / Almeida, Janete D

Histopathology

2015 Volume 66, Issue 3, Page(s) 463–464

MeSH term(s)	Humans ; Lichen Planus, Oral/pathology
Language	English
Publishing date	2015-02
Publishing country	England
Document type	Letter
ZDB-ID	131914-0
ISSN	1365-2559 ; 0309-0167
ISSN (online)	1365-2559
ISSN	0309-0167
DOI	10.1111/his.12538
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Article ; Online: Straight and offset implant placement under axial and nonaxial loads in implant-supported prostheses: strain gauge analysis.

Abreu, Celina Wanderley / Nishioka, Renato Sussumu / Balducci, Ivan / Consani, Rafael Leonardo Xediek

Journal of prosthodontics : official journal of the American College of Prosthodontists

2012 Volume 21, Issue 7, Page(s) 535–539

Abstract: Purpose: The aim of this in vitro study was to quantify strain development during axial and nonaxial loading using strain gauge analysis for three-element implant-supported FPDs, varying the arrangement of implants: straight line (L) and offset (O).: ... ...

Abstract	Purpose: The aim of this in vitro study was to quantify strain development during axial and nonaxial loading using strain gauge analysis for three-element implant-supported FPDs, varying the arrangement of implants: straight line (L) and offset (O). Materials and methods: Three Morse taper implants arranged in a straight line and three implants arranged in an offset configuration were inserted into two polyurethane blocks. Microunit abutments were screwed onto the implants, applying a 20 Ncm torque. Plastic copings were screwed onto the abutments, which received standard wax patterns cast in Co-Cr alloy (n = 10). Four strain gauges were bonded onto the surface of each block tangential to the implants. The occlusal screws of the superstructure were tightened onto microunit abutments using 10 Ncm and then axial and nonaxial loading of 30 Kg was applied for 10 seconds on the center of each implant and at 1 and 2 mm from the implants, totaling nine load application points. The microdeformations determined at the nine points were recorded by four strain gauges, and the same procedure was performed for all of the frameworks. Three loadings were made per load application point. The magnitude of microstrain on each strain gauge was recorded in units of microstrain (με). The data were analyzed statistically by two-way ANOVA and Tukey's test (p < 0.05). Results: The configuration factor was statistically significant (p= 0.0004), but the load factor (p= 0.2420) and the interaction between the two factors were not significant (p= 0.5494). Tukey's test revealed differences between axial offset (με) (183.2 ± 93.64) and axial straight line (285.3 ± 61.04) and differences between nonaxial 1 mm offset (201.0 ± 50.24) and nonaxial 1 mm straight line (315.8 ± 59.28). Conclusion: There was evidence that offset placement is capable of reducing the strain around an implant. In addition, the type of loading, axial force or nonaxial, did not have an influence until 2 mm.
MeSH term(s)	Alveolar Process/physiology ; Chromium Alloys ; Dental Implantation, Endosseous/methods ; Dental Implants ; Dental Prosthesis Design ; Dental Prosthesis, Implant-Supported ; Dental Stress Analysis/methods ; Denture, Partial, Fixed ; Humans ; Stress, Mechanical ; Weight-Bearing
Chemical Substances	Chromium Alloys ; Dental Implants
Language	English
Publishing date	2012-10
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1197213-0
ISSN	1532-849X ; 1059-941X
ISSN (online)	1532-849X
ISSN	1059-941X
DOI	10.1111/j.1532-849X.2012.00871.x
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Article ; Online: Enterococcus Species in the Oral Cavity: Prevalence, Virulence Factors and Antimicrobial Susceptibility.

Komiyama, Edson Yukio / Lepesqueur, Laura Soares Souto / Yassuda, Cinthia Gomes / Samaranayake, Lakshman P / Parahitiyawa, Nipuna B / Balducci, Ivan / Koga-Ito, Cristiane Yumi

PloS one

2016 Volume 11, Issue 9, Page(s) e0163001

Abstract: Enterococci are considered as transient constituent components of the oral microbiome that may cause a variety of oral and systemic infections. As there is sparse data on the oral enterococcal prevalence, we evaluated the Enterococcus spp. and their ... ...

Abstract	Enterococci are considered as transient constituent components of the oral microbiome that may cause a variety of oral and systemic infections. As there is sparse data on the oral enterococcal prevalence, we evaluated the Enterococcus spp. and their virulence attributes including antimicrobial resistance in a healthy Brazilian cohort. A total of 240 individuals in different age groups were studied (children 4-11 yrs, adolescents 12-17 yrs, young adults 18-29 yrs, adults 30-59 yrs, elderly over 60 yrs). Oral rinses were collected and isolates were identified by API 20 Strep and confirmed by 16S rDNA sequencing. E. faecalis isolates, in particular, were evaluated for virulence attributes such as their biofilm formation potential, and susceptibility to antimicrobials and an antiseptic, chlorhexidine gluconate. A total of 40 individuals (16.6%) and 10% children, 4% adolescents, 14% young adults, 30% adults, and 25% elderly carried oral enterococci. The oral enterococcal burden in adolescents was significantly lower than in the adults (p = 0.000) and elderly (p = 0.004). The proportion of carriers was higher among females (p = 0.001). E. faecalis was the most frequent isolate in all the age groups (p = 0.000), followed by E. durans and E. faecium. Whilst all the clinical isolates were able to form biofilms, only a proportion of them were able to produce lipase (92%), hemolysin (38%), and gelatinase (39%). Of all the isolates 53.8% were resistant to tetracycline, 12.3% to amoxicillin, 16.0% to ampicillin, 20.8% to chloramphenicol and 43.4% to erythromycin. None of the isolates were resistant to vancomycin. Our data suggest that in this Brazilian cohort the oral cavity may act as a significant reservoir of rather virulent and antibiotic resistant enterococci, with an increasing degree of carriage in the adults and elderly. Hence clinicians should be cognizant of this silent reservoir of virulent enterococci that may pose a particular threat of nosocomial infection.
MeSH term(s)	Adolescent ; Adult ; Brazil ; Child ; Child, Preschool ; Cohort Studies ; Enterococcus/drug effects ; Enterococcus/genetics ; Enterococcus/isolation & purification ; Enterococcus/pathogenicity ; Genes, Bacterial ; Humans ; Microbial Sensitivity Tests ; Middle Aged ; Mouth/microbiology ; RNA, Ribosomal, 16S/genetics ; Virulence ; Young Adult
Chemical Substances	RNA, Ribosomal, 16S
Language	English
Publishing date	2016-09-15
Publishing country	United States
Document type	Journal Article
ISSN	1932-6203
ISSN (online)	1932-6203
DOI	10.1371/journal.pone.0163001
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Article ; Online: High doses of alcohol during pregnancy cause DNA damages in osteoblasts of newborns rats.

Carvalho, Isabel Chaves Silva / Dutra, Tamires Pereira / Andrade, Dennia Perez De / Balducci, Ivan / Pacheco-Soares, Cristina / Rocha, Rosilene Fernandes da

Birth defects research. Part A, Clinical and molecular teratology

2016 Volume 106, Issue 2, Page(s) 122–132

Abstract: Background: Alcohol exerts teratogenic effects and its consumption during pregnancy can cause deficit of bone development. The aim of the current study was to evaluate the genotoxic effects of prenatal exposure to ethanol on newborn rat osteoblasts.: ... ...

Abstract	Background: Alcohol exerts teratogenic effects and its consumption during pregnancy can cause deficit of bone development. The aim of the current study was to evaluate the genotoxic effects of prenatal exposure to ethanol on newborn rat osteoblasts. Methods: Wistar rats were initially divided into two groups: Ethanol group which received Ethanol 20% V/V in liquid diet and solid diet ad libitum, and Control group, which received solid diet and water ad libitum. Each group received a specific diet for 8 weeks before breeding and throughout three weeks of gestation and the treatment was finished on the day the pups were killed. On the fifth day of life, the pups from each group were killed for removal of the calvaria and isolation of osteogenic cells by sequential enzymatic digestion. The cells were cultured for a maximum period of 14 days. The detection of genotoxic effects of alcohol was investigated by the comet and the micronucleus assay. Results: Micronucleus and comet assay showed significant increases in DNA damage at 7 days in Ethanol group (p = 0.0302, p = 0.0446, respectively). However, at 14 days both assay showed no significant difference between the groups (p = 0.6194, p = 0.8326, respectively). Conclusion: Our results showed that prenatal exposure to ethanol induced DNA damage in osteoblasts, as shown by micronucleus formation and higher percentage of DNA in the comet tail. It can be concluded that prenatal exposure to ethanol damages osteoblast DNA in newborns exposed to high doses of ethanol during pregnancy, suggesting that prenatal ethanol consumption has a direct effect on fetal osteoblasts.
MeSH term(s)	Animals ; Animals, Newborn ; Bone Development/drug effects ; Cells, Cultured ; Comet Assay ; DNA Damage ; Ethanol/toxicity ; Female ; Fetal Alcohol Spectrum Disorders/physiopathology ; Micronuclei, Chromosome-Defective/chemically induced ; Micronucleus Tests ; Osteoblasts/drug effects ; Pregnancy ; Rats ; Rats, Wistar
Chemical Substances	Ethanol (3K9958V90M)
Language	English
Publishing date	2016-02
Publishing country	United States
Document type	Journal Article
ZDB-ID	2104792-3
ISSN	1542-0760 ; 1542-0752 ; 1542-9733 ; 1542-975X
ISSN (online)	1542-0760
ISSN	1542-0752 ; 1542-9733 ; 1542-975X
DOI	10.1002/bdra.23468
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Article ; Online: Effect of HIV infection in the micronuclei frequency on the oral mucosa.

Lima, Celina Faig / Alves, Monica Ghislaine Oliveira / Furtado, Juvencio Jose Duailibe / Marcucci, Marcelo / Balducci, Ivan / Almeida, Janete Dias

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology

2016 Volume 46, Issue 8, Page(s) 644–648

Abstract: Background: The genotoxic impact of HIV infection on the oral cavity malignancies is unknown. The aim of this study was to evaluate the effect of HIV infection in micronucleus (MN) frequency on the oral mucosa of HIV+ patients and establish a ... ...

Abstract	Background: The genotoxic impact of HIV infection on the oral cavity malignancies is unknown. The aim of this study was to evaluate the effect of HIV infection in micronucleus (MN) frequency on the oral mucosa of HIV+ patients and establish a relationship with early cytogenetic changes in oral carcinogenesis. Methods: Thirty HIV+ individuals who are under highly active antiretroviral therapy (HAART) and 30 non-HIV patients were evaluated. Two smears were taken from the lateral border of the tongue and mouth floor and stained by Feulgen. The frequency of MN was examined in 3000 cells per subject under common microscopy. Results: MN analysis showed no significant difference between groups by Mann-Whitney U-test for total MNs (P = 0.178). The presence of single MN was greater in control group with statistical significance (P = 0.009), while in HIV group, multiple MNs were exhibited in higher mean. Conclusions: HIV patients under HAART therapy and low viral load values showed higher frequency of multiple MNs, which, although not statistically significant, may be caused by the action of the Vpr gene, an accessory gene of HIV. These results corroborate the theory of HIV infection cytogenetic damage.
MeSH term(s)	Adult ; Aged ; Antiretroviral Therapy, Highly Active ; Case-Control Studies ; Female ; HIV Infections/drug therapy ; HIV Infections/pathology ; Humans ; Male ; Micronuclei, Chromosome-Defective/statistics & numerical data ; Micronucleus Tests ; Middle Aged ; Mouth Mucosa/pathology ; Viral Load
Language	English
Publishing date	2016-12-24
Publishing country	Denmark
Document type	Journal Article
ZDB-ID	1021270-x
ISSN	1600-0714 ; 0904-2512
ISSN (online)	1600-0714
ISSN	0904-2512
DOI	10.1111/jop.12527
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Article ; Online: Mucus extravasation and retention phenomena

Almeida Janete D / Cabral Luiz / Balducci Ivan / Zerbinatti Daniel CZ / Hayashida Alethea M

BMC Oral Health, Vol 10, Iss 1, p

a 24-year study

2010 Volume 15

Abstract: Abstract Background Mucoceles are benign lesions related to the minor salivary glands and their respective ducts frequently affecting oral structures which are generally asymptomatic. Mucoceles are generally characterized by swollen nodular lesions ... ...

Abstract	Abstract Background Mucoceles are benign lesions related to the minor salivary glands and their respective ducts frequently affecting oral structures which are generally asymptomatic. Mucoceles are generally characterized by swollen nodular lesions preferentially located on the lower lip and differ from the so-called ranulas, which are lesions located on the floor of the mouth and related to the sublingual or submandibular glands. Methods The objective of the present study was to analyze data such as age, gender, race and site of the lesion of 173 mucocele cases diagnosed at the Discipline of Stomatology, São José dos Campos Dental School, UNESP, over a period of 24 years (April 1980 to February 2003). Results Of the 173 cases analyzed, 104 (60.12%) were females and 69 (39.88%) were males. Age ranged from 4 to 70 years (mean ± SD: 17 ± 9.53) and most patients were in the second decade of life (n = 86, 49.42%); white (n = 124, 71.68%). The lower lip was the site most frequently affected by the lesions (n = 135, 78.03%), whereas the lowest prevalence was observed for the soft palate, buccal mucosa, and lingual frenum. Conclusion In this study, mucoceles predominated in white female subjects in the second decade of life, with the lower lip being the most frequently affected site.
Keywords	Dentistry ; RK1-715 ; Medicine ; R ; DOAJ:Dentistry ; DOAJ:Health Sciences
Language	English
Publishing date	2010-06-01T00:00:00Z
Publisher	BioMed Central
Document type	Article ; Online
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