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  1. Article: Reduction of Post-Surgical Facial Edema Following Bromelain and Coumarin Intake in Traumatology: A Prospective Study with 100 Patients.

    Consorti, Giuseppe / Monarchi, Gabriele / Paglianiti, Mariagrazia / Betti, Enrico / Balercia, Paolo

    Journal of clinical medicine

    2024  Volume 13, Issue 4

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2024-02-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13040922
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  2. Article: Partial Parotidectomy under Local Anaesthesia without Regional Block Assisted by Electromyographic Facial Nerve Monitoring - A Case Report.

    Girotto, Riccardo / De Feudis, Francesco / Balercia, Paolo

    Annals of maxillofacial surgery

    2023  Volume 13, Issue 1, Page(s) 127–129

    Abstract: The rationale: This study describes a partial parotidectomy (PP) under local anaesthesia (LA) without regional block (LAwRB) assisted by electromyographic monitoring of the facial nerve, to consolidate the feasibility, efficacy and safety of these ... ...

    Abstract The rationale: This study describes a partial parotidectomy (PP) under local anaesthesia (LA) without regional block (LAwRB) assisted by electromyographic monitoring of the facial nerve, to consolidate the feasibility, efficacy and safety of these procedures without general anaesthesia (GA).
    Patient concerns: An 82-year-old with a lump in the left parotid gland suspected for non-Hodgkin lymphoma (NHL) needed a histological examination to start chemotherapy.
    Diagnosis and treatments: Because of multiple comorbidities, the authors performed a PP under LAwRB electromyographically guided by the NIM Vital (Medtronic)™.
    Outcomes: The procedure was quick and did not require conversion to GA. The histopathological examination confirmed the NHL. No haematoma, sialocoele, earlobe numbness and transient or permanent facial palsy were observed.
    Take-away lessons: The electrophysiologic monitoring of the facial nerve improves the efficacy, safety and feasibility of parotid surgery under LA, avoiding adverse effects of GA, need of regional block and reducing hospital stay.
    Language English
    Publishing date 2023-07-25
    Publishing country India
    Document type Case Reports
    ZDB-ID 2696991-9
    ISSN 2249-3816 ; 2231-0746
    ISSN (online) 2249-3816
    ISSN 2231-0746
    DOI 10.4103/ams.ams_89_22
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  3. Article ; Online: The Impact of Professional Oral Hygiene in Orthognathic Surgery.

    Consorti, Giuseppe / Monarchi, Gabriele / Betti, Enrico / Balercia, Paolo

    The Journal of craniofacial surgery

    2023  Volume 34, Issue 7, Page(s) e646–e648

    Abstract: Introduction: Oral hygiene represents a fundamental element with regard to outcomes in oral and maxillofacial surgery. Both basic hygiene that the patient must perform daily at home and obviously professional hygiene aimed at preventing any ... ...

    Abstract Introduction: Oral hygiene represents a fundamental element with regard to outcomes in oral and maxillofacial surgery. Both basic hygiene that the patient must perform daily at home and obviously professional hygiene aimed at preventing any complications in the surgical field.
    Methods: Patients undergoing orthognathic surgery in our Department of Maxillofacial Surgery in Ancona, in a total number of 137 in the period studied (2016-2021), were divided into 2 groups: period 1, (2016-2018) and period 2 (2019-2021). The division into 2 groups derives from the establishment of a professional oral hygiene protocol established starting from January 2019 and put into practice by dental hygienists. The protocol consists of preoperative counseling and above all very precise instructions in the postoperative so as to optimize the oral hygiene process, assist in the best possible wound healing and reduce possible postoperative complications. Anamnestic, cephalometric data, measurements of the distances between certain landmarks for the evaluation of facial edema, patient-referred pain, accurate intraoral and extraoral physical examination both pre and postoperative, and complications were collected for each patient.
    Conclusions: The main goal of the study authors set is to evaluate the effective impact of professional oral hygiene in the pre and postoperative management of patients undergoing orthognathic surgery, taking into account parameters, such as facial edema and pain, and using evaluation scales, making a comparison with the data reported in the 3 years before and after the establishment of the protocol applied by the authors.
    MeSH term(s) Humans ; Orthognathic Surgery ; Oral Hygiene ; Orthognathic Surgical Procedures ; Facial Bones ; Edema
    Language English
    Publishing date 2023-06-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1159501-2
    ISSN 1536-3732 ; 1049-2275
    ISSN (online) 1536-3732
    ISSN 1049-2275
    DOI 10.1097/SCS.0000000000009460
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  4. Article ; Online: Potential dual synergy between electrochemotherapy and sequence of immunotherapies in metastatic melanoma: A case report.

    Morgese, Francesca / De Feudis, Francesco / Balercia, Paolo / Berardi, Rossana

    Molecular and clinical oncology

    2023  Volume 18, Issue 2, Page(s) 8

    Abstract: Immune checkpoint inhibitors have changed the natural history of advanced melanoma. Despite this, a notable proportion of patients immediately relapse or develop resistance during immunotherapy, especially with the appearance of superficial metastases ... ...

    Abstract Immune checkpoint inhibitors have changed the natural history of advanced melanoma. Despite this, a notable proportion of patients immediately relapse or develop resistance during immunotherapy, especially with the appearance of superficial metastases and consequently with a dramatic impact on clinical outcomes. Local treatment by electrochemotherapy (ECT), parallel to regional control with palliative aim, seems to release neoantigens potentially determining a significant systemic anticancer immune reactivation. The present study reported a case of a patient with metastatic melanoma receiving Pembrolizumab, electrochemotherapy and then Ipilimumab for in-transit and finally locoregional lymph nodes and distant bone metastases with experience of clinic-radiological remission. Specifically, the present patient progressed during adjuvant treatment with in-transit metastases on the scalp; he underwent two cycle of ECT obtaining partial and then unexpected and very fast nearly complete response with the Ipilimumab treatment. Concomitantly, he developed grade 4 endocrine adverse events (hypophysitis and diabetes mellitus type I) as immune-related toxicities. At 12 months from ECT the patient is in ECOG Performance Status 0 and he has resumed a regular social life. In our experience, ECT in two administrations increased and accelerated the response of Ipilimumab. The present confirmed its promising contribution in inducing a powerful immune response in order to overcome primary or acquired resistance to immune checkpoint inhibitors such as anti-programmed death antigen-1 drugs.
    Language English
    Publishing date 2023-01-10
    Publishing country England
    Document type Case Reports
    ZDB-ID 2796865-0
    ISSN 2049-9469 ; 2049-9450
    ISSN (online) 2049-9469
    ISSN 2049-9450
    DOI 10.3892/mco.2023.2604
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  5. Article: Prelamination of the Forearm Flap for Soft Palate Reconstruction: A Case Report.

    Girotto, Riccardo / Monarchi, Gabriele / De Feudis, Francesco / Paglianiti, Mariagrazia / Balercia, Paolo

    Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India

    2023  Volume 75, Issue 4, Page(s) 2829–2835

    Abstract: Microsurgical reconstruction is nowadays the treatment of choice of several head and neck deformities that otherwise could be repaired with limited or unsatisfactory results. The forearm free flap has its own goals expecially the possibility to ... ...

    Abstract Microsurgical reconstruction is nowadays the treatment of choice of several head and neck deformities that otherwise could be repaired with limited or unsatisfactory results. The forearm free flap has its own goals expecially the possibility to reconstruct small and extremely specialized anatomical structures such as the soft palate. The abuse of drugs like cocaine, generally taken by sniffing, can produce vascular impairment in nasal and oral tissues producing, as long as the abuse is kept, necrosis of facial anatomical structures and increase of the empty space in the depth of the face or nose. The consequences are generally represented by palatal fistulas or defect, leak of food or drink from the nose, and rhinolalia. Prelamination of the flap before microvascular transfer ensures not only preparation ofadequate tissue volume to resurface the defect but also optimization of the venous outflow. This two times approach, consisting first in preparation and then elevation/transfer of the flap, gives the chances to ensure viability of the flap itself and organize the surgical strategy several times to reduce forthcoming complications. The authors believe that this technical modification could be used for many other chronic defects in the head and neck region but could also be extended, with experience, to bigger defects.
    Supplementary information: The online version contains supplementary material available at 10.1007/s12070-023-03870-7.
    Language English
    Publishing date 2023-05-17
    Publishing country India
    Document type Journal Article
    ZDB-ID 1471137-0
    ISSN 0973-7707 ; 2231-3796 ; 0019-5421
    ISSN (online) 0973-7707
    ISSN 2231-3796 ; 0019-5421
    DOI 10.1007/s12070-023-03870-7
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    Zs.A 5300: Show issues Location:
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  6. Article: The superior eyelid crease approach with retroseptal dissection: A modified access to the superomedial intraconal space. Treatment of a cavernous hemangioma: Case report and literature review.

    De Feudis, Francesco / Girotto, Riccardo / Balercia, Paolo

    National journal of maxillofacial surgery

    2021  Volume 12, Issue 3, Page(s) 410–413

    Abstract: The orbit can be affected by primary intraconal lesions as well as cavernous hemangiomas. This article illustrates for the first time the retroseptal dissection (RD) route combined to the superior eyelid crease approach (SECA) to treat a symptomatic ... ...

    Abstract The orbit can be affected by primary intraconal lesions as well as cavernous hemangiomas. This article illustrates for the first time the retroseptal dissection (RD) route combined to the superior eyelid crease approach (SECA) to treat a symptomatic hemangioma inside the superomedial intraconal space. It also reviews the main studies about the argument. A 42-year-old woman affected by a mild painful proptosis and some accommodation difficulties in her right eye. The magnetic resonance imaging revealed a soft intraconal mass in the superomedial quadrant of the right orbit. The lesion was removed performing a SECA with RD through an incision inside a natural eyelid crease. Disappearance of pain with an improvement of accommodation was reported immediately. During the whole follow-up, the visual acuity, field examinations, and ocular motility did not reveal any impairment. Our approach represents a valid, quick, not technically demanding and mini-invasive method to access the superomedial intraconal space. Finally, it gives excellent functional and cosmetic results.
    Language English
    Publishing date 2021-12-13
    Publishing country India
    Document type Case Reports
    ZDB-ID 2653583-X
    ISSN 2229-3418 ; 0975-5950
    ISSN (online) 2229-3418
    ISSN 0975-5950
    DOI 10.4103/njms.NJMS_420_21
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  7. Article ; Online: Palatal reconstruction with tunnellized Bichat fat pad flap after tumor resection.

    Consorti, Giuseppe / Catarzi, Lisa / Valassina, Davide / Balercia, Paolo

    Minerva dental and oral science

    2021  Volume 71, Issue 3, Page(s) 168–173

    Abstract: Background: Reconstruction of palate defects following tumor ablative surgery can be a challenging problem. Different methods have been suggested over the time for the reconstruction of postoperative palatal defects. Since the first report of the Bichat ...

    Abstract Background: Reconstruction of palate defects following tumor ablative surgery can be a challenging problem. Different methods have been suggested over the time for the reconstruction of postoperative palatal defects. Since the first report of the Bichat fat pad flap in1977, it has become one of the most used flaps for the reconstruction of palate after tumor excision. We report our results using the tunnellized Bichat fat pad (BFP) flap for 23 cases of palate reconstruction after minor salivary glands tumor excision.
    Methods: The authors performed a tunnellized Bichat fat pad flap for primary reconstruction of small- medium-sized surgical defects of the palate in 23 patients suffering from minor salivary glands palatal tumors in the period between 2016 and 2019. Each case was reviewed for primary pathologic findings, wound healing, postoperative complications.
    Results: All 23 tunnellized BFP procedures showed excellent recovery and uneventful follow-up. With this technique after 12 months follow-up complete wound healing after only 4 weeks without complication was observed.
    Conclusions: The tunnellized BFP flap is useful, easy, and uncomplicated new alternative method for primary reconstruction of small to medium-sized palatal surgical defects, that can be performed with a very low morbidity. Submucosal tunnel for the pedicle passage introduced by the Authors adds some advantages in final outcomes with less discomfort for the patients, proving to be a technique able to adds itself to surgical reconstructive technique available today.
    MeSH term(s) Adipose Tissue/surgery ; Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Middle Aged ; Neoplasms/surgery ; Palate/surgery ; Reconstructive Surgical Procedures/methods ; Surgical Flaps/surgery
    Language English
    Publishing date 2021-04-30
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 3062693-6
    ISSN 2724-6337
    ISSN (online) 2724-6337
    DOI 10.23736/S2724-6329.21.04459-9
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    Zs.B 159: Show issues Location:
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  8. Article: New Tunneled Buccal Fat Pad Flap for Palatal Reconstruction.

    Consorti, Giuseppe / Catarzi, Lisa / Messi, Marco / Valassina, Davide / Balercia, Paolo

    Craniomaxillofacial trauma & reconstruction

    2021  Volume 15, Issue 1, Page(s) 90–94

    Abstract: In the palatal defects due to surgical resection, flap selection is very important for a correct reconstruction. Different methods have been suggested over the time, however the pedicled buccal fat pad is a simple, effective, reliable flap for ... ...

    Abstract In the palatal defects due to surgical resection, flap selection is very important for a correct reconstruction. Different methods have been suggested over the time, however the pedicled buccal fat pad is a simple, effective, reliable flap for reconstruction after palate tumor resection. The aim of the present study is to introduce a new surgical technique for palate reconstruction with pedicled buccal fat pad flap exposing the advantages. The Authors performed this procedure in 17 patients in order to treat medium-sized oncologic surgical defect of palate region in the period between 2016 and 2019. Complete wound healing after only 4 weeks without complication after 12 months follow-up was observed. This is the first cases series described with this new technique.
    Language English
    Publishing date 2021-01-19
    Publishing country United States
    Document type Journal Article
    ISSN 1943-3875
    ISSN 1943-3875
    DOI 10.1177/1943387520988433
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  9. Article: Ruptured proximal pontine artery aneurysm and association with cerebellopontine angle cistern arterial venous malformation fed by the same artery: A surgical challenge.

    Gladi, Maurizio / Di Rienzo, Alessandro / Fasinella, Maria Rossella / Aiudi, Denis / Balercia, Paolo / Dobran, Mauro / Iacoangeli, Maurizio

    Surgical neurology international

    2023  Volume 14, Page(s) 352

    Abstract: Background: The coexistence of hyper-inflow aneurysms and cerebellopontine angle cistern (CPAc) arterial venous malformations (AVMs) have been rarely reported and most commonly associated with high risk of bleeding.: Case descriptions: We present two ...

    Abstract Background: The coexistence of hyper-inflow aneurysms and cerebellopontine angle cistern (CPAc) arterial venous malformations (AVMs) have been rarely reported and most commonly associated with high risk of bleeding.
    Case descriptions: We present two cases of CPAc AVMs admitted for acute subarachnoid hemorrhage from rupture of a parent right pontine artery aneurysm. Admission history, neurology at presentation, pre/post-operative imaging, approach selection, and results are thoroughly reviewed and presented. The acute origin angle of the vessel from the basilar artery made both malformations unsuitable for endovascular treatment. The surgical strategy was differently tailored in the two patients, respectively, using a Le Fort I/transclival and a Kawase approach. The aneurysm was clipped in the first case, and the AVM was excised in the second one, as required by the anatomical context. Aneurysm exclusion and AVM size reduction were obtained in the first case, while complete AVM removal and later aneurysm disappearance were obtained in the second one. A high-flow cerebrospinal fluid leak in the first case was successfully treated by an endoscopic approach. Both patients experienced a satisfactory neurological outcome in the follow-up.
    Conclusion: Pontine artery aneurysms, especially when associated with CPAc AVMs, represent a surgical challenge, due to their rarity and anatomical peculiarity, which typically requires complex operative approaches. Multimodal preoperative imaging, appropriate timing, and accurate target selection, together with versatile strategies, are the keys to a successful treatment.
    Language English
    Publishing date 2023-10-06
    Publishing country United States
    Document type Case Reports
    ISSN 2229-5097
    ISSN 2229-5097
    DOI 10.25259/SNI_246_2023
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  10. Article ; Conference proceedings: Skull Base and Craniofacial Approaches to Minimize Approach-Related Morbidity for Intracerebral Complex Neoplastic and Vascular Lesions

    Capece, Mara / Balercia, Paolo / Dobran, Mauro / Carrassi, Erika / Fasinella, Maria Rossella / Liverotti, Valentina / Mattioli, Andrea / Iacoangeli, Maurizio

    Journal of Neurological Surgery Part B: Skull Base

    2022  Volume 83, Issue S 01

    Event/congress 31st Annual Meeting North American Skull Base Society, Online, 2022-02-18
    Language English
    Publishing date 2022-02-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 2654269-9
    ISSN 2193-634X ; 2193-6331
    ISSN (online) 2193-634X
    ISSN 2193-6331
    DOI 10.1055/s-0042-1743881
    Database Thieme publisher's database

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