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  1. Artikel: Social Determinants of Health and Cardiologist Involvement in the Care of Adults Hospitalized for Heart Failure.

    Zhang, David T / Onyebeke, Chukwuma / Nahid, Musarrat / Balkan, Lauren / Musse, Mahad / Pinheiro, Laura C / Sterling, Madeline R / Durant, Raegan W / Brown, Todd M / Levitan, Emily B / Safford, Monika M / Goyal, Parag

    medRxiv : the preprint server for health sciences

    2023  

    Abstract: Introduction: The involvement of a cardiologist in the care of adults during a hospitalization for heart failure (HF) is associated with reduced rates of in-hospital mortality and hospital readmission. However, not all patients see a cardiologist when ... ...

    Abstract Introduction: The involvement of a cardiologist in the care of adults during a hospitalization for heart failure (HF) is associated with reduced rates of in-hospital mortality and hospital readmission. However, not all patients see a cardiologist when they are hospitalized for HF. Since reasons for this are not entirely clear, we sought to determine whether social determinants of health (SDOH) are associated with cardiologist involvement in the management of adults hospitalized for HF. We hypothesized that SDOH would be inversely associated with cardiologist involvement in the care of adults hospitalized for HF.
    Methods: We included adult participants from the national REasons for Geographic And Racial Difference in Stroke (REGARDS) cohort, who experienced an adjudicated hospitalization for HF between 2009 and 2017. We excluded participants who were hospitalized at institutions that lacked cardiology services (n=246). We examined nine candidate SDOH, which align with the Healthy People 2030 conceptual model: Black race, social isolation (0-1 visits from a family or friend in the past month), social network/caregiver availability (having someone to care for them if ill), educational attainment < high school, annual household income < $35,000, living in rural areas, living in a zip code with high poverty, living in a Health Professional Shortage Area, and residing in a state with poor public health infrastructure. The primary outcome was cardiologist involvement, a binary variable which was defined as involvement of a cardiologist as the primary responsible clinician or as a consultant, collected via chart review. We examined associations between each SDOH and cardiologist involvement using Poisson regression with robust standard errors. Candidate SDOH with statistically significant associations (p<0.10) were retained for multivariable analysis. Potential confounders/covariates for the multivariable analysis included age, race, sex, HF characteristics, comorbidities, and hospital characteristics.
    Results: We examined 876 participants hospitalized at 549 unique US hospitals. The median age was 77.5 years (IQR 71.0-83.7), 45.9% were female, 41.4% were Black, and 56.2% had low income. Low household income (<$35,000/year) was the only SDOH that had a statistically significant association with cardiologist involvement in a bivariate analysis (RR: 0.88 [95% CI: 0.82-0.95]). After adjusting for potential confounders, low income remained inversely associated (RR: 0.89 [95% CI: 0.82-0.97]).
    Conclusions: Adults with low household income were 11% less likely to have a cardiologist involved in their care during a hospitalization for HF. This suggests that socioeconomic status may implicitly bias the care provided to patients hospitalized for HF.
    Sprache Englisch
    Erscheinungsdatum 2023-03-24
    Erscheinungsland United States
    Dokumenttyp Preprint
    DOI 10.1101/2023.03.23.23287671
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Social Determinants of Health and Cardiologist Involvement in the Care of Adults Hospitalized for Heart Failure.

    Zhang, David T / Onyebeke, Chukwuma / Nahid, Musarrat / Balkan, Lauren / Musse, Mahad / Pinheiro, Laura C / Sterling, Madeline R / Durant, Raegan W / Brown, Todd M / Levitan, Emily B / Safford, Monika M / Goyal, Parag

    JAMA network open

    2023  Band 6, Heft 11, Seite(n) e2344070

    Abstract: Importance: Involvement of a cardiologist in the care of adults during a hospitalization for heart failure (HF) is associated with reduced rates of in-hospital mortality and hospital readmission. However, not all patients see a cardiologist when they ... ...

    Abstract Importance: Involvement of a cardiologist in the care of adults during a hospitalization for heart failure (HF) is associated with reduced rates of in-hospital mortality and hospital readmission. However, not all patients see a cardiologist when they are hospitalized for HF.
    Objective: To determine whether social determinants of health (SDOH) are associated with cardiologist involvement in the management of adults hospitalized for HF.
    Design, setting, and participants: This retrospective cohort study used data from the Reasons for Geographic and Racial Difference in Stroke (REGARDS) cohort. Participants included adults who experienced an adjudicated hospitalization for HF between 2009 and 2017 in all 48 contiguous states in the US. Data analysis was performed from November 2022 to January 2023.
    Exposures: A total of 9 candidate SDOH, aligned with the Healthy People 2030 conceptual model, were examined: Black race, social isolation, social network and/or caregiver availability, educational attainment less than high school, annual household income less than $35 000, living in rural area, living in a zip code with high poverty, living in a Health Professional Shortage Area, and living in a state with poor public health infrastructure.
    Main outcomes and measures: The primary outcome was cardiologist involvement, defined as involvement of a cardiologist as the primary responsible clinician or as a consultant. Bivariate associations between each SDOH and cardiologist involvement were examined using Poisson regression with robust SEs.
    Results: The study included 1000 participants (median [IQR] age, 77.8 [71.5-84.0] years; 479 women [47.9%]; 414 Black individuals [41.4%]; and 492 of 876 with low income [56.2%]) hospitalized at 549 unique US hospitals. Low annual household income (<$35 000) was the only SDOH with a statistically significant association with cardiologist involvement (relative risk, 0.88; 95% CI, 0.82-0.95). In a multivariable analysis adjusting for age, race, sex, HF characteristics, comorbidities, and hospital characteristics, low income remained inversely associated with cardiologist involvement (relative risk, 0.89; 95% CI, 0.82-0.97).
    Conclusions and relevance: This cohort study found that adults with low household income were 11% less likely than adults with higher incomes to have a cardiologist involved in their care during a hospitalization for HF. These findings suggest that socioeconomic status may bias the care provided to patients hospitalized for HF.
    Mesh-Begriff(e) Humans ; Adult ; Female ; Aged ; Cohort Studies ; Retrospective Studies ; Social Determinants of Health ; Cardiologists ; Heart Failure/epidemiology ; Heart Failure/therapy
    Sprache Englisch
    Erscheinungsdatum 2023-11-01
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2023.44070
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Allostatic load and incident heart failure in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study.

    Park, Christine / Ringel, Joanna B / Pinheiro, Laura C / Morris, Alanna A / Sterling, Madeline / Balkan, Lauren / Banerjee, Samprit / Levitan, Emily B / Safford, Monika M / Goyal, Parag

    BMC cardiovascular disorders

    2023  Band 23, Heft 1, Seite(n) 340

    Abstract: Background: Allostatic load (AL) is the physiologic "wear and tear" on the body from stress. Yet, despite stress being implicated in the development heart failure (HF), it is unknown whether AL is associated with incident HF events.: Methods: We ... ...

    Abstract Background: Allostatic load (AL) is the physiologic "wear and tear" on the body from stress. Yet, despite stress being implicated in the development heart failure (HF), it is unknown whether AL is associated with incident HF events.
    Methods: We examined 16,765 participants without HF at baseline from the REasons for Geographic and Racial Differences in Stroke (REGARDS) cohort. The main exposure was AL score quartile. AL was determined according to 11 physiologic parameters, whereby each parameter was assigned points (0-3) based on quartiles within the sample, and points were summed to create a total AL score ranging from 0-33. The outcome was incident HF event. We examined the association between AL quartile (Q1-Q4) and incident HF events using Cox proportional hazards models, adjusted for demographics, socioeconomic factors, and lifestyle.
    Results: The mean age was 64 ± 9.6 years, 61.5% were women, and 38.7% were Black participants. Over a median follow up of 11.4 years, we observed 750 incident HF events (635 HF hospitalizations and 115 HF deaths). Compared to the lowest AL quartile (Q1), the fully adjusted hazards of an incident HF event increased in a graded fashion: Q2 HR 1.49 95% CI 1.12-1.98; Q3 HR 2.47 95% CI 1.89-3.23; Q4 HR 4.28 95% CI 3.28-5.59. The HRs for incident HF event in the fully adjusted model that also adjusted for CAD were attenuated, but remained significant and increased in a similar, graded fashion by AL quartile. There was a significant age interaction (p-for-interaction < 0.001), whereby the associations were observed across each age stratum, but the HRs were highest among those aged < 65 years.
    Conclusion: AL was associated with incident HF events, suggesting that AL could be an important risk factor and potential target for future interventions to prevent HF.
    Mesh-Begriff(e) Humans ; Female ; Middle Aged ; Aged ; Male ; Allostasis ; Race Factors ; Heart Failure/diagnosis ; Heart Failure/epidemiology ; Heart Failure/etiology ; Stroke/diagnosis ; Stroke/epidemiology ; Stroke/complications ; Risk Factors
    Sprache Englisch
    Erscheinungsdatum 2023-07-04
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2059859-2
    ISSN 1471-2261 ; 1471-2261
    ISSN (online) 1471-2261
    ISSN 1471-2261
    DOI 10.1186/s12872-023-03371-z
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Association of Perceived Stress With Incident Heart Failure.

    Balkan, Lauren / Ringel, Joanna B / Levitan, Emily B / Khodneva, Yulia A / Pinheiro, Laura C / Sterling, Madeline R / Kim, Samuel M / Kronish, Ian M / Jackson, Elizabeth A / Durant, Raegan / Safford, Monika / Goyal, Parag

    Journal of cardiac failure

    2022  Band 28, Heft 9, Seite(n) 1401–1410

    Abstract: Background: The relationship between psychological stress and heart failure (HF) has not been well studied. We sought to assess the relationship between perceived stress and incident HF.: Methods: We used data from the national REasons for Geographic ...

    Abstract Background: The relationship between psychological stress and heart failure (HF) has not been well studied. We sought to assess the relationship between perceived stress and incident HF.
    Methods: We used data from the national REasons for Geographic And Racial Differences in Stroke (REGARDS) study, a large prospective biracial cohort study that enrolled community-dwellers aged 45 years and older between 2003 and 2007, with follow-up. We included participants free of suspected prevalent HF who completed the Cohen 4-item Perceived Stress Scale (PSS-4). Our outcome variables were incident HF event, HF with reduced ejection fraction events, and HF with preserved ejection fraction events. We estimated Cox proportional hazard models to determine if PSS-4 quartiles were independently associated with incident HF events, adjusting for sociodemographics, social support, unhealthy behaviors, comorbid conditions, and physiologic parameters. We also tested interactions by baseline statin use, given its anti-inflammatory properties.
    Results: Among 25,785 participants with a mean age of 64 ± 9.3 years, 55% were female and 40% were Black. Over a median follow-up of 10.1 years, 1109 ± 4.3% experienced an incident HF event. In fully adjusted models, the PSS-4 was not associated with HF or HF with reduced ejection fraction. However, PSS-4 quartiles 2-4 (compared with the lowest quartile) were associated with incident HF with preserved ejection fraction (Q2 hazard ratio 1.37, 95% confidence interval 1.00-1.88; Q3 hazard ratio 1.42, 95% confidence interval 1.03-1.95; Q4 hazard ratio 1.41, 95% confidence interval 1.04-1.92). Notably, this association was attenuated among participants who took a statin at baseline (P for interaction = .07).
    Conclusions: Elevated perceived stress was associated with incident HF with preserved ejection fraction but not HF with reduced ejection fraction.
    Mesh-Begriff(e) Aged ; Cohort Studies ; Female ; Heart Failure/diagnosis ; Heart Failure/epidemiology ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors ; Male ; Middle Aged ; Prospective Studies ; Risk Factors ; Stress, Psychological/epidemiology ; Stroke Volume/physiology
    Chemische Substanzen Hydroxymethylglutaryl-CoA Reductase Inhibitors
    Sprache Englisch
    Erscheinungsdatum 2022-05-11
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1281194-4
    ISSN 1532-8414 ; 1071-9164
    ISSN (online) 1532-8414
    ISSN 1071-9164
    DOI 10.1016/j.cardfail.2022.04.013
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: The Dietary Approaches to Stop Hypertension (DASH) Diet Pattern and Incident Heart Failure.

    Goyal, Parag / Balkan, Lauren / Ringel, Joanna B / Hummel, Scott L / Sterling, Madeline R / Kim, Samuel / Arora, Pankaj / Jackson, Elizabeth A / Brown, Todd M / Shikany, James M / Judd, Suzanne E / Safford, Monika M / Levitan, Emily B

    Journal of cardiac failure

    2021  Band 27, Heft 5, Seite(n) 512–521

    Abstract: Background: The Dietary Approaches to Stop Hypertension (DASH) diet pattern has shown some promise for preventing heart failure (HF), but studies have been conflicting.: Objective: To determine whether the DASH diet pattern was associated with ... ...

    Abstract Background: The Dietary Approaches to Stop Hypertension (DASH) diet pattern has shown some promise for preventing heart failure (HF), but studies have been conflicting.
    Objective: To determine whether the DASH diet pattern was associated with incident HF in a large biracial and geographically diverse population.
    Methods and results: Among participants in the REasons for Geographic And Racial Differences in Stroke (REGARDS) cohort study of adults aged ≥45 years who were free of suspected HF at baseline in 2003-2007, the DASH diet score was derived from the baseline food frequency questionnaire. The main outcome was incident HF defined as the first adjudicated HF hospitalization or HF death through December 31, 2016. We estimated hazard ratios for the associations of DASH diet score quartiles with incident HF, and incident HF with reduced ejection fraction and HF with preserved ejection fraction using the Lunn-McNeil extension to the Cox model. We tested for several prespecified interactions, including with age. Compared with the lowest quartile, individuals in the second to fourth DASH diet score quartiles had a lower risk for incident HF after adjustment for sociodemographic and health characteristics: quartile 2 hazard ratio, 0.69 (95% confidence interval [CI], 0.56-0.85); quartile 3 hazard ratio, 0.71 (95% CI, 0.58-0.87); and quartile 4 hazard ratio, 0.73 (95% CI, 0.58-0.92). When stratifying results by age, quartiles 2-4 had a lower hazard for incident HF among those age <65 years, quartiles 3-4 had a lower hazard among those age 65-74, and the quartiles had similar hazard among those age ≥75 years (P
    Conclusions: DASH diet adherence was inversely associated with incident HF, specifically among individuals <75 years old.
    Mesh-Begriff(e) Adult ; Aged ; Cohort Studies ; Diet ; Dietary Approaches To Stop Hypertension ; Heart Failure/epidemiology ; Heart Failure/prevention & control ; Humans ; Incidence
    Sprache Englisch
    Erscheinungsdatum 2021-06-24
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1281194-4
    ISSN 1532-8414 ; 1071-9164
    ISSN (online) 1532-8414
    ISSN 1071-9164
    DOI 10.1016/j.cardfail.2021.01.011
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Relation of a Simple Cardiac Co-Morbidity Count and Cardiovascular Readmission After a Heart Failure Hospitalization.

    Visaria, Aayush / Balkan, Lauren / Pinheiro, Laura C / Bryan, Joanna / Banerjee, Samprit / Sterling, Madeline R / Krishnan, Udhay / Horn, Evelyn M / Safford, Monika M / Goyal, Parag

    The American journal of cardiology

    2020  Band 125, Heft 10, Seite(n) 1529–1535

    Abstract: Although several risk calculators are available to determine risk for readmission following a heart failure (HF) hospitalization, none provide information on cause-specific readmission. Understanding risk for cause-specific readmission could aid in ... ...

    Abstract Although several risk calculators are available to determine risk for readmission following a heart failure (HF) hospitalization, none provide information on cause-specific readmission. Understanding risk for cause-specific readmission could aid in developing a targeted approach to reducing readmissions. We sought to determine if a simple cardiac co-morbidity count could identify individuals at high risk for a cardiovascular (CV) readmission following a HF hospitalization. Using the Nationwide Readmissions Database, we examined nonfatal hospital discharges with a principal diagnosis of HF. We calculated a 0 to 3 cardiac co-morbidity count based on the presence of coronary artery disease, atrial arrhythmia, and/or ventricular arrhythmia. We used a multinomial logistic regression to determine if the cardiac co-morbidity count was independently associated with CV readmission or non-CV readmission, adjusting for patient- and hospital-level confounders. In 380,075 discharges, 28% had a co-morbidity count of 0, 47% had a count of 1, 23% had a count of 2, and 2% had a count of 3. In a fully adjusted model, cardiac co-morbidity count was independently associated with CV readmission: compared with individuals with a count of 0, the relative risk for those with a count of 1 was 1.27 (95% confidence interval [CI]: 1.23 to 1.31); for those with a count of 2 was 1.40 (95% CI: 1.35 to 1.46); and for those with a count of 3 was 1.36 (95% CI: 1.23 to 1.51). Cardiac co-morbidity count was not independently associated with non-CV readmission. In conclusion, we found that a simple cardiac co-morbidity count was independently associated with increased risk of CV but not non-CV readmission.
    Mesh-Begriff(e) Age Factors ; Aged ; Algorithms ; Female ; Heart Failure/complications ; Heart Failure/mortality ; Hospital Mortality ; Humans ; Male ; Middle Aged ; Patient Readmission/statistics & numerical data ; Risk Factors ; Shock, Cardiogenic/complications ; Shock, Cardiogenic/mortality ; Sleep Apnea, Obstructive/complications ; Sleep Apnea, Obstructive/mortality ; Survival Rate ; United States
    Sprache Englisch
    Erscheinungsdatum 2020-03-05
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 80014-4
    ISSN 1879-1913 ; 0002-9149
    ISSN (online) 1879-1913
    ISSN 0002-9149
    DOI 10.1016/j.amjcard.2020.02.018
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Biomarkers and cardiovascular outcomes in chimeric antigen receptor T-cell therapy recipients.

    Mahmood, Syed S / Riedell, Peter A / Feldman, Stephanie / George, Gina / Sansoterra, Stephen A / Althaus, Thomas / Rehman, Mahin / Mead, Elena / Liu, Jennifer E / Devereux, Richard B / Weinsaft, Jonathan W / Kim, Jiwon / Balkan, Lauren / Barbar, Tarek / Lee Chuy, Katherine / Harchandani, Bhisham / Perales, Miguel-Angel / Geyer, Mark B / Park, Jae H /
    Palomba, M Lia / Shouval, Roni / Tomas, Ana A / Shah, Gunjan L / Yang, Eric H / Gaut, Daria L / Rothberg, Michael V / Horn, Evelyn M / Leonard, John P / Van Besien, Koen / Frigault, Matthew J / Chen, Zhengming / Mehrotra, Bhoomi / Neilan, Tomas G / Steingart, Richard M

    European heart journal

    2023  Band 44, Heft 22, Seite(n) 2029–2042

    Abstract: Aims: Chimeric antigen receptor T-cell therapy (CAR-T) harnesses a patient's immune system to target cancer. There are sparse existing data characterizing death outcomes after CAR-T-related cardiotoxicity. This study examines the association between CAR- ...

    Abstract Aims: Chimeric antigen receptor T-cell therapy (CAR-T) harnesses a patient's immune system to target cancer. There are sparse existing data characterizing death outcomes after CAR-T-related cardiotoxicity. This study examines the association between CAR-T-related severe cardiovascular events (SCE) and mortality.
    Methods and results: From a multi-centre registry of 202 patients receiving anti-CD19 CAR-T, covariates including standard baseline cardiovascular and cancer parameters and biomarkers were collected. Severe cardiovascular events were defined as a composite of heart failure, cardiogenic shock, or myocardial infarction. Thirty-three patients experienced SCE, and 108 patients died during a median follow-up of 297 (interquartile range 104-647) days. Those that did and did not die after CAR-T were similar in age, sex, and prior anthracycline use. Those who died had higher peak interleukin (IL)-6 and ferritin levels after CAR-T infusion, and those who experienced SCE had higher peak IL-6, C-reactive protein (CRP), ferritin, and troponin levels. The day-100 and 1-year Kaplan-Meier overall mortality estimates were 18% and 43%, respectively, while the non-relapse mortality (NRM) cumulative incidence rates were 3.5% and 6.7%, respectively. In a Cox model, SCE occurrence following CAR-T was independently associated with increased overall mortality risk [hazard ratio (HR) 2.8, 95% confidence interval (CI) 1.6-4.7] after adjusting for age, cancer type and burden, anthracycline use, cytokine release syndrome grade ≥ 2, pre-existing heart failure, hypertension, and African American ancestry; SCEs were independently associated with increased NRM (HR 3.5, 95% CI 1.4-8.8) after adjusting for cancer burden.
    Conclusion: Chimeric antigen receptor T-cell therapy recipients who experience SCE have higher overall mortality and NRM and higher peak levels of IL-6, CRP, ferritin, and troponin.
    Mesh-Begriff(e) Humans ; Receptors, Chimeric Antigen/therapeutic use ; Interleukin-6 ; Biomarkers ; Neoplasms ; Heart Failure ; C-Reactive Protein ; Troponin ; Cell- and Tissue-Based Therapy
    Chemische Substanzen Receptors, Chimeric Antigen ; Interleukin-6 ; Biomarkers ; C-Reactive Protein (9007-41-4) ; Troponin
    Sprache Englisch
    Erscheinungsdatum 2023-03-20
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/ehad117
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Imaging Utilization and Outcomes in Vulnerable Populations during COVID-19 in New York City.

    Toy, Dennis / Mahmood, Syed S / Rotman, Jessica / Weisman, Stacey Verzosa / Escalon, Joanna G / Legasto, Alan C / Cheng, Edward P / McKenney, Anna Sophia / Barbar, Tarek / Balkan, Lauren / Chen, Yunchan / Razavi, Peyman / Zainul, Omar / Abedian, Sajjad / Gruden, James F / Truong, Quynh A

    Radiology. Cardiothoracic imaging

    2020  Band 2, Heft 6, Seite(n) e200464

    Abstract: Background: Coronavirus disease 2019 (COVID-19) affects vulnerable populations (VP) adversely.: Purpose: To evaluate overall imaging utilization in vulnerable subgroups (elderly, racial/ethnic minorities, socioeconomic status [SES] disadvantage) and ... ...

    Abstract Background: Coronavirus disease 2019 (COVID-19) affects vulnerable populations (VP) adversely.
    Purpose: To evaluate overall imaging utilization in vulnerable subgroups (elderly, racial/ethnic minorities, socioeconomic status [SES] disadvantage) and determine if a particular subgroup has worse outcomes from COVID-19.
    Materials/methods: Of 4110 patients who underwent COVID-19 testing from March 3-April 4, 2020 at NewYork-Presbyterian Hospital (NYP) health system, we included 1121 COVID-19 positive adults (mean age 59±18 years, 59% male) from two academic hospitals and evaluated imaging utilization rates and outcomes, including mortality.
    Results: Of 897 (80%) VP, there were 465 (41%) elderly, 380 (34%) racial/ethnic minorities, and 479 (43%) SES disadvantage patients. Imaging was performed in 88% of patients and mostly portable/bedside studies, with 87% of patients receiving chest radiographs. There were 83% hospital admissions, 25% ICU admissions, 23% intubations, and 13% deaths. Elderly patients had greater imaging utilization, hospitalizations, ICU/intubation requirement, longer hospital stays, and >4-fold increase in mortality compared to non-elderlies (adjusted hazard ratio[aHR] 4.79, p<0.001). Self-reported minorities had fewer ICU admissions (p=0.03) and reduced hazard for mortality (aHR 0.53, p=0.004; complete case analysis: aHR 0.39, p<0.001 excluding "not reported"; sensitivity analysis: aHR 0.61, p=0.005 "not reported" classified as minorities) with similar imaging utilization, compared to non-minorities. SES disadvantage patients had similar imaging utilization and outcomes as compared to their counterparts.
    Conclusions: In a predominantly hospitalized New York City cohort, elderly patients are at highest mortality risk. Racial/ethnic minorities and SES disadvantage patients fare better or similarly to their counterparts, highlighting the critical role of access to inpatient medical care during the COVID-19 pandemic.
    Sprache Englisch
    Erscheinungsdatum 2020-12-17
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 2638-6135
    ISSN (online) 2638-6135
    DOI 10.1148/ryct.2020200464
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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