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  1. Book: Primer of robotic & telerobotic surgery

    Ballantyne, Garth H.

    2004  

    Author's details ed. by Garth H. Ballantyne
    Keywords Surgical Procedures, Operative / methods ; Robotics / instrumentation ; Robotics / methods ; Surgical Equipment
    Language English
    Size XVII, 248 S. : Ill., graph. Darst.
    Publisher Lippincott Williams & Wilkins
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT014023530
    ISBN 0-7817-4844-5 ; 978-0-7817-4844-5
    Database Catalogue ZB MED Medicine, Health

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  2. Book: Laparoscopic surgery

    Ballantyne, Garth H. / Leahy, Patrick F. / Modlin, Irvin M.

    1994  

    Author's details Garth H. Ballantyne ; Patrick F. Leahy ; Irvin M. Modlin
    Keywords Laparoscopy / methods ; Surgical Procedures, Operative / methods ; Minimal-invasive Chirurgie
    Subject MIC ; Minimal invasive surgery ; Mikro-invasive Chirurgie ; Endoskopische Chirurgie ; Operative Endoskopie ; Chirurgische Endoskopie ; Therapeutische Endoskopie ; Video-assistierte Telechirurgie ; Schlüssellochchirurgie ; Knopflochchirurgie ; Less invasive surgery
    Language English
    Size XX, 710 S. : zahlr. Ill., graph. Darst.
    Edition 1. print
    Publisher Saunders
    Publishing place Philadephia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT006439114
    ISBN 0-7216-6648-5 ; 978-0-7216-6648-8
    Database Catalogue ZB MED Medicine, Health

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  3. Article: Peptide YY(1-36) and peptide YY(3-36): Part I. Distribution, release and actions.

    Ballantyne, Garth H

    Obesity surgery

    2006  Volume 16, Issue 5, Page(s) 651–658

    Abstract: Peptide YY (PYY) is a 36 amino acid, straight chain polypeptide, which is co-localized with GLP-1 in the L-type endocrine cells of the GI mucosa. PYY shares structural homology with neuropeptide Y (NPY) and pancreatic polypeptide (PP), and together form ... ...

    Abstract Peptide YY (PYY) is a 36 amino acid, straight chain polypeptide, which is co-localized with GLP-1 in the L-type endocrine cells of the GI mucosa. PYY shares structural homology with neuropeptide Y (NPY) and pancreatic polypeptide (PP), and together form the Neuropeptide Y Family of Peptides, which is also called the Pancreatic Polypeptide-Fold Family of Peptides. PYY release is stimulated by intraluminal nutrients, including glucose, bile salts, lipids, short-chain fatty acids and amino acids. Regulatory peptides such as cholecystokinin (CCK), vasoactive intestinal polypeptide (VIP), gastrin and GLP-1 modulate PYY release. The proximal GI tract may also participate in the regulation of PYY release through vagal fibers. After release, dipeptidyl peptidase IV (DPP-IV; CD 26) cleaves the N-terminal tyrosine-proline residues forming PYY(3-36). PYY(1-36) represents about 60% and PYY(3-36) 40% of circulating PYY. PYY acts through Y-receptor subtypes: Y1, Y2, Y4 and Y5 in humans. PYY(1-36) shows high affinity to all four receptors while PYY(3-36) is a specific Y2 agonist. PYY inhibits many GI functions, including gastric acid secretion, gastric emptying, small bowel and colonic chloride secretion, mouth to cecum transit time, pancreatic exocrine secretion and pancreatic insulin secretion. PYY also promotes postprandial naturesis and elevates systolic and diastolic blood pressure. PYY(1-36) and PYY(3-36) cross the blood-brain barrier and participate in appetite and weight control regulation. PYY(1-36) acting through Y1- and Y5-receptors increases appetite and stimulates weight gain. PYY(3-36) acting through Y2-receptors on NPY-containing cells in the arcuate nucleus inhibits NPY release and, thereby, decreases appetite and promotes weight loss. PYY may play a primary role in the appetite suppression and weight loss observed after bariatric operations.
    MeSH term(s) Adenosine Deaminase/physiology ; Animals ; Appetite/physiology ; Arcuate Nucleus of Hypothalamus/physiology ; Dipeptidyl Peptidase 4/physiology ; Gastrointestinal Tract/physiology ; Glucagon-Like Peptides/metabolism ; Glycoproteins/physiology ; Humans ; Kidney/physiology ; Peptide Fragments ; Peptide YY/metabolism ; Peptide YY/physiology ; Weight Gain/physiology
    Chemical Substances Glycoproteins ; Peptide Fragments ; Peptide YY (106388-42-5) ; peptide YY (3-36) (123583-37-9) ; Glucagon-Like Peptides (62340-29-8) ; DPP4 protein, human (EC 3.4.14.5) ; Dipeptidyl Peptidase 4 (EC 3.4.14.5) ; Adenosine Deaminase (EC 3.5.4.4) ; peptide YY (1-36) (T2670C12I5)
    Language English
    Publishing date 2006-05-06
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1381/096089206776944959
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Peptide YY(1-36) and peptide YY(3-36): Part II. Changes after gastrointestinal surgery and bariatric surgery.

    Ballantyne, Garth H

    Obesity surgery

    2006  Volume 16, Issue 6, Page(s) 795–803

    Abstract: Peptide YY (PYY) is secreted as a 36 amino acid, straight chain polypeptide, and is found in greatest concentrations in the terminal ileum, colon and rectum. After secretion, dipeptidyl peptidase IV (DPP-IV) cleaves the N-terminal Tyrosine-Proline ... ...

    Abstract Peptide YY (PYY) is secreted as a 36 amino acid, straight chain polypeptide, and is found in greatest concentrations in the terminal ileum, colon and rectum. After secretion, dipeptidyl peptidase IV (DPP-IV) cleaves the N-terminal Tyrosine-Proline residues from PYY(1-36), producing PYY(3-36). PYY(1-36) acts at all four human Y receptors, Y1, Y2, Y4 and Y5, while PYY(336) is a specific Y2 receptor agonist. PYY participates in the regulation of appetite and weight balance through hypothalamic-based mechanisms. PYY(1-36) stimulates appetite and weight gain through Y1 and Y5 receptors. PYY(3-36) suppresses appetite and stimulates weight loss through Y2 receptors. GI diseases that cause malabsorption increase both basal and meal-stimulated PYY levels. In contrast, obesity decreases both basal and meal-stimulated PYY levels. Mutations in the human PYY and Y2 receptor genes may contribute to the development of obesity. Small bowel resection elevates PYY levels in humans. Colon resections increase PYY levels in animal models but not in man. PYY changes following bariatric operations are incompletely studied. Vertical banded gastroplasty, open Roux-en-Y gastric bypass and jejunoileal bypass significantly elevate basal and meal-stimulated PYY levels. In dogs with Pavlov pouches, Roux-en-Y duodenojejunostomy (duodenal switch) increases PYY levels compared to Roux-en-Y gastrojejunostomy. DPP-IV activity is increased in obese individuals and remains increased after biliopancreatic diversion. Thus, diseases or operations which cause malabsorption, elevate basal and meal-stimulated PYY levels. Bariatric operations also increase basal and meal-stimulated PYY levels. This suggests that the combination of increased PYY levels and elevated levels of DPP-IV observed after bariatric operations may generate increased circulating levels of PYY(3-36), leading to hypothalamic-mediated suppression of appetite and promotion of weight loss through Y2 receptor mediated mechanisms.
    MeSH term(s) Animals ; Appetite/physiology ; Bariatric Surgery ; Biliopancreatic Diversion ; Colonic Pouches ; Digestive System Surgical Procedures ; Dipeptidyl Peptidase 4/blood ; Gastric Bypass ; Gastrointestinal Diseases/blood ; Gastrointestinal Diseases/surgery ; Gastroplasty ; Gastrostomy ; Humans ; Jejunoileal Bypass ; Jejunostomy ; Obesity/genetics ; Obesity, Morbid/blood ; Obesity, Morbid/surgery ; Peptide Fragments ; Peptide YY/blood ; Polymorphism, Genetic ; Postoperative Period ; Proctocolectomy, Restorative
    Chemical Substances Peptide Fragments ; Peptide YY (106388-42-5) ; peptide YY (3-36) (123583-37-9) ; Dipeptidyl Peptidase 4 (EC 3.4.14.5)
    Language English
    Publishing date 2006-06
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1381/096089206777346619
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Measuring outcomes following bariatric surgery: weight loss parameters, improvement in co-morbid conditions, change in quality of life and patient satisfaction.

    Ballantyne, Garth H

    Obesity surgery

    2003  Volume 13, Issue 6, Page(s) 954–964

    Abstract: Restrictive and particularly malabsorptive bariatric operations achieve significant sustained weight loss. Results from different operations have been difficult to compare. The aims of this review are: 1) to indicate the limitations of outcomes reported ... ...

    Abstract Restrictive and particularly malabsorptive bariatric operations achieve significant sustained weight loss. Results from different operations have been difficult to compare. The aims of this review are: 1) to indicate the limitations of outcomes reported as weight-related parameters; 2) to document some of the patient characteristics that impact weight loss; 3) to assess the literature documenting improvement in obesity-related medical conditions; and 4) to review studies that quantitate changes in health-related quality of life (QoL). Weight-related parameters such as body mass index and % excess weight inconsistently correlate with body fat. Direct determination of body fat with bioelectric impedance may offer more reliable outcome parameters. Patient characteristics such as gender, age, weight, body mass index, ethnicity, race and socioeconomic status affect weight loss following bariatric operations. Improvements in co-morbid conditions are poorly documented in many studies. Standardized instruments that assess health-related QoL have shown differing values. SF-36 has given inconsistent results following bariatric operations. Both BAROS and IWQoL-Lite have demonstrated significant improvements after surgery. Bariatric surgeons have rarely used patient satisfaction as an outcome parameter. This review suggests that bariatric operations should be judged by change in fat mass or fat mass index, improvement in obesity-related medical conditions, change in health-related QoL as judged by standardized instruments, and level of patient satisfaction. In addition, surgeons should characterize their study population and report outcomes for sub-populations.
    MeSH term(s) Adipose Tissue/physiopathology ; Body Mass Index ; Comorbidity ; Electric Impedance ; Gastric Bypass/methods ; Gastroplasty/methods ; Humans ; Patient Satisfaction ; Quality of Life ; Treatment Outcome ; Weight Loss/physiology
    Language English
    Publishing date 2003-12
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1381/096089203322618867
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: The pitfalls of laparoscopic surgery: challenges for robotics and telerobotic surgery.

    Ballantyne, Garth H

    Surgical laparoscopy, endoscopy & percutaneous techniques

    2002  Volume 12, Issue 1, Page(s) 1–5

    Abstract: After its debut in 1988, laparoscopic cholecystectomy rapidly became the standard of care for cholelithiasis, yet very few surgeons use minimally invasive techniques for other abdominal operations. Why do most surgeons continue to perform traditional ... ...

    Abstract After its debut in 1988, laparoscopic cholecystectomy rapidly became the standard of care for cholelithiasis, yet very few surgeons use minimally invasive techniques for other abdominal operations. Why do most surgeons continue to perform traditional open gastrointestinal operations? We believe that the answer to this question lies in the fact that advanced laparoscopic operations are difficult to learn, perform, and master. A number of inherent pitfalls of laparoscopy hinder the performance of these operations even after the surgeon has accumulated years of experience. These pitfalls include an unstable video camera platform, limited motion (degrees of freedom) of straight laparoscopic instruments, two-dimensional imaging, and poor ergonomics for the surgeon. Inexperienced or bored laparoscopic camera-holders move the camera frequently and rotate it away from the horizon. The long, straight laparoscopic instruments are limited in their motion by the fixation enforced by the abdominal wall trocars. Similarly, the standard two-dimensional video imaging used in most laparoscopic operations impedes the surgeon's depth perception, compounding the limitations of laparoscopic instruments. In addition, surgeons are forced to assume ergonomically awkward stances in performing many laparoscopic operations. These four factors hinder a surgeon's efforts to learn and to perform advanced laparoscopic operations, significantly lengthening the learning curve. The articles presented in this issue suggest that robotics and telerobotics offer solutions to these nagging pitfalls of laparoscopic surgery.
    MeSH term(s) Cholecystectomy, Laparoscopic/trends ; Equipment Design ; Ergonomics ; Humans ; Laparoscopes ; Laparoscopy/adverse effects ; Minimally Invasive Surgical Procedures/adverse effects ; Minimally Invasive Surgical Procedures/methods ; Minimally Invasive Surgical Procedures/trends ; Robotics/methods ; Robotics/trends
    Language English
    Publishing date 2002-05-13
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1475108-2
    ISSN 1534-4908 ; 1530-4515 ; 1051-7200
    ISSN (online) 1534-4908
    ISSN 1530-4515 ; 1051-7200
    DOI 10.1097/00129689-200202000-00001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Sentinel Contributions of US Department of Veterans Affairs Surgeons in Shaping the Face of Health Care.

    Lipshy, Kenneth A / Itani, Kamal / Chu, Danny / Bahadursingh, Anil / Spector, Seth / Raman, Kathleen / Dardik, Alan / Tzeng, Edith / Ballantyne, Garth H / John, Preeti R / Cmolik, Brian / Maloney, James / Kozol, Robert / Longo, Walter E

    JAMA surgery

    2021  Volume 156, Issue 4, Page(s) 380–386

    Abstract: The vast accomplishments of the US Department of Veterans Affairs (VA) during the past century have contributed to the advancement of medicine and benefited patients worldwide. This article highlights some of those accomplishments and the advantages in ... ...

    Abstract The vast accomplishments of the US Department of Veterans Affairs (VA) during the past century have contributed to the advancement of medicine and benefited patients worldwide. This article highlights some of those accomplishments and the advantages in the VA system that promulgated those successes. Through its affiliation with medical schools, its formation of a structured research and development program, its Cooperative Studies Program, and its National Surgical Quality Improvement Program, the VA has led the world in the progress of health care. The exigencies of war led not only to the organization of VA health care but also to groundbreaking, landmark developments in colon surgery; surgical treatments for vascular disease, including vascular grafts, carotid surgery, and arteriovenous dialysis fistulas; cardiac surgery, including implantable cardiac pacemaker and coronary artery bypass surgery; and the surgical management of many conditions, such as hernias. The birth of successful liver transplantation was also seen within the VA, and countless other achievements have benefited patients around the globe. These successes have created an environment where residents and medical students are able to obtain superb education and postgraduate training and where faculty are able to develop their clinical and academic careers.
    MeSH term(s) Humans ; Organizational Objectives ; Quality Assurance, Health Care ; Surgical Procedures, Operative/education ; Surgical Procedures, Operative/trends ; United States ; United States Department of Veterans Affairs
    Language English
    Publishing date 2021-01-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2701841-6
    ISSN 2168-6262 ; 2168-6254
    ISSN (online) 2168-6262
    ISSN 2168-6254
    DOI 10.1001/jamasurg.2020.6372
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book: Atlas of laparoscopic surgery

    Ballantyne, Garth H

    2000  

    Author's details [edited by] Garth H. Ballantyne
    MeSH term(s) Laparoscopy/methods
    Language English
    Size xv, 537 p.
    Publisher Saunders
    Publishing place Philadelphia
    Document type Book
    ISBN 9780721663265 ; 0721663265
    Database Catalogue of the US National Library of Medicine (NLM)

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  9. Book: Atlas of laparoscopic surgery

    Ballantyne, Garth H

    2000  

    Author's details [ed. by] Garth H. Ballantyne
    Language English
    Size XV, 537 S, Ill., graph. Darst
    Edition 1. ed
    Publisher Saunders
    Publishing place Philadelphia u.a.
    Document type Book
    ISBN 0721663265 ; 9780721663265
    Database Former special subject collection: coastal and deep sea fishing

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  10. Article: Hand-assisted laparoscopic colectomy: evolution to a clinically useful technique.

    Ballantyne, Garth H / Leahy, Patrick F

    Diseases of the colon and rectum

    2004  Volume 47, Issue 5, Page(s) 753–765

    Abstract: Purpose: Hand-assisted laparoscopic colectomy has traversed three phases of distinct development. This review was designed to trace the evolution of hand-assisted colectomy from an infrequently used technique to a clinically useful surgical approach to ... ...

    Abstract Purpose: Hand-assisted laparoscopic colectomy has traversed three phases of distinct development. This review was designed to trace the evolution of hand-assisted colectomy from an infrequently used technique to a clinically useful surgical approach to diseases of the colon and rectum.
    Methods: This review compiles previously reported and published experiences with hand-assisted laparoscopic colectomy.
    Results: During the first phase of development of hand-assisted laparoscopic colectomy, surgeons explored what could be accomplished by a hand inserted into the abdomen through the specimen extraction site as an adjunct to laparoscopic techniques. Case reports and small trials found that manually assisted laparoscopic techniques permitted more rapid completion of laparoscopic-assisted colectomies. In the second phase, surgeons used early devices that facilitated the insertion of the surgeon's hand into the abdomen and helped to maintain the pneumoperitoneum. Larger series and small, randomized trials indicated a time-saving advantage to hand-assisted techniques and similar short-term outcomes as laparoscopic-assisted colectomies. In the current third phase, surgeons are using a new generation of hand-access devices that extend the options for hand-assisted techniques. These devices, like earlier devices, facilitate hand insertion, protect the wound, act as the retrieval site for the specimen, and serve as the portal for construction of extracorporeal anastomoses. In addition, these new devices can serve as laparoscopic trocar sites. This permits selective use of hand-assisted and laparoscopic-assisted techniques at various times in the same operation. These new devices have not undergone clinical trials, and therefore, a final appraisal must await future publication of outcomes.
    Conclusions: Hand-assisted laparoscopic colectomy has evolved into a clinically useful surgical technique. New devices facilitate the performance of these operations and permit the surgeon to switch between hand-assisted and laparoscopic techniques.
    MeSH term(s) Colectomy/instrumentation ; Colectomy/methods ; Hand ; Humans ; Laparoscopes ; Laparoscopy/methods
    Language English
    Publishing date 2004-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 212581-x
    ISSN 1530-0358 ; 0012-3706
    ISSN (online) 1530-0358
    ISSN 0012-3706
    DOI 10.1007/s10350-003-0108-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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