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  1. Article: The clinical outcome of HIV infection at a tertiary care center in Riyadh, Saudi Arabia.

    Baadani, Abeer M / Ballool, Sulafa / Alhemyadi, Salwa / Sallam, Lina / ALsufyani, Eid / Alghamdi, Alaa / Alfahad, Wafaa

    Saudi medical journal

    2020  Volume 41, Issue 9, Page(s) 965–970

    Abstract: Objectives: To investigate clinical characteristics and the outcome of people living with HIV (PLWHIV) at tertiary care center in Riyadh, Saudi Arabia. Methods: The present retrospective, observational study was carried between 2000-2019 at Prince ... ...

    Abstract Objectives: To investigate clinical characteristics and the outcome of people living with HIV (PLWHIV) at tertiary care center in Riyadh, Saudi Arabia. Methods: The present retrospective, observational study was carried between 2000-2019 at Prince Sultan Military Medical City (PSMMC), Riyadh, Saudi Arabia. The demographic and clinical characteristics of  137 PLWHIV patients were collected by reviewing the medical data record.  Results: Of the total 137 PLWHIV, 78.8% were male and 21.2% were female. At care entry, the most opportunistic infections found were the cytomegalovirus infections. cytomegalovirus (CMV) infections in 13.8% of patients, tuberculosis  (8%), AIDS associated malignancy (10.9%), hepatitis B (5.8%), NTM (3.6%), hepatitis C (2.2%). In the present study, more than half of the patients received integrase based combination therapy. The highest number (n=20) of patients were diagnosed in 2018. Conclusions: Our findings describe the clinical characteristics and outcomes of PLWHIV at a major tertiary referral hospital in Saudi Arabia. The non AIDS related disease is the major cause of death in HIV infected patients. Early diagnosis and initiation of antiretroviral therapy resulted in a significant decrease in morbidity and mortality.
    MeSH term(s) AIDS-Related Opportunistic Infections/complications ; AIDS-Related Opportunistic Infections/epidemiology ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Cohort Studies ; Cytomegalovirus Infections/complications ; Cytomegalovirus Infections/epidemiology ; Female ; HIV Infections/complications ; HIV Infections/drug therapy ; HIV Infections/epidemiology ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Saudi Arabia/epidemiology ; Tertiary Care Centers ; Treatment Outcome ; Young Adult
    Language English
    Publishing date 2020-08-13
    Publishing country Saudi Arabia
    Document type Journal Article
    ZDB-ID 392302-2
    ISSN 1658-3175 ; 0379-5284
    ISSN (online) 1658-3175
    ISSN 0379-5284
    DOI 10.15537/smj.2020.9.25274
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Strongyloides

    Elzein, Fatehi Elnour / Alsaeed, Mohammed / Ballool, Sulafa / Attia, Ashraf

    Case reports in transplantation

    2016  Volume 2016, Page(s) 1786265

    Abstract: The mortality ... ...

    Abstract The mortality in
    Keywords covid19
    Language English
    Publishing date 2016-09-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2627657-4
    ISSN 2090-6951 ; 2090-6943
    ISSN (online) 2090-6951
    ISSN 2090-6943
    DOI 10.1155/2016/1786265
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Efficacy of tocilizumab in patients with severe COVID-19: Survival and clinical outcomes.

    Al-Baadani, Abeer / Eltayeb, Nazik / Alsufyani, Eid / Albahrani, Salma / Basheri, Shareefah / Albayat, Hawra / Batubara, Enas / Ballool, Sulafa / Al Assiri, Ayed / Faqihi, Fahad / Musa, Ali B / Robert, Asirvatham A / Alsherbeeni, Nisreen / Elzein, Fatehi

    Journal of infection and public health

    2021  Volume 14, Issue 8, Page(s) 1021–1027

    Abstract: Background: SARS-CoV-2 is associated with a severe inflammatory response contributing to respiratory and systemic manifestations, morbidity, and mortality in patients with coronavirus disease 2019 (COVID-19).: Methods: Tocilizumab (TCZ) efficacy on ... ...

    Abstract Background: SARS-CoV-2 is associated with a severe inflammatory response contributing to respiratory and systemic manifestations, morbidity, and mortality in patients with coronavirus disease 2019 (COVID-19).
    Methods: Tocilizumab (TCZ) efficacy on mortality and length of hospital stay was retrospectively evaluated in patients who received TCZ and compared with that in controls with a similar severity of COVID-19. The primary endpoint was survival probability on day 28. The secondary endpoints included survival at day 14 and length of hospital stay.
    Results: Of the 148 patients included in the study, 62 received TCZ and standard of care, whereas 86 served as a control group and received only standard of care. The two groups were similar, although TCZ-treated patients were more likely to exhibit hypertension (46.7% vs. 29.8%), chronic kidney disease (14.5% vs. 1.1%), and high Charlson score (1.18 vs. 1.00; p = 0.006) and less likely to receive corticosteroid treatment (48.5% vs. 93.0%). TCZ was associated with lower mortality on both day 28 (16.1% vs. 37.2%, p = 0.004) and day 14 (9.7% vs. 24.4%, p = 0.022). The hospital stay was longer in the TCZ-treated than in the control group (15.6 ± 7.59 vs.17.7 ± 7.8 days, p = 0.103). Ten patients (16.0%) in the TCZ-treated group developed infections.
    Conclusion: TCZ was associated with a lower likelihood of death despite resulting in higher infection rates and a non-significant longer hospital stay.
    MeSH term(s) Antibodies, Monoclonal, Humanized ; Humans ; Retrospective Studies ; SARS-CoV-2 ; Treatment Outcome ; COVID-19 Drug Treatment
    Chemical Substances Antibodies, Monoclonal, Humanized ; tocilizumab (I031V2H011)
    Language English
    Publishing date 2021-05-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 2467587-8
    ISSN 1876-035X ; 1876-0341
    ISSN (online) 1876-035X
    ISSN 1876-0341
    DOI 10.1016/j.jiph.2021.05.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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