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Article: Intraoperative application of 5-fluorouracil and mitomycin C aschemoadjuvants in primary pterygium surgery.

Altay, Yeşim / Balta, Özgür

2016 Volume 46, Issue 2, Page(s) 321–327

Abstract: Background/aim: To compare the effectiveness of intraoperative 5 fluorouracil (5-FU) and mitomycin C (MMC) application in preventing recurrence following primary pterygium excision.: Materials and methods: This was a prospective clinical trial that ... ...

Abstract	Background/aim: To compare the effectiveness of intraoperative 5 fluorouracil (5-FU) and mitomycin C (MMC) application in preventing recurrence following primary pterygium excision. Materials and methods: This was a prospective clinical trial that included 93 patients with primary pterygia assigned to three treatment groups in which 29 patients received an intraoperative application of 25 mg/mL 5-FU for 5 min, 32 patients received an intraoperative application of 0.02% MMC for 5 min, and 32 patients underwent only surgical excision (the control group). Follow-up visits were done on postoperative days 1, 3, 7, 15, and 30, and then every month. Results: After a mean follow-up of 14 months, the surgical excision recurrence rates in the 5-FU, MMC, and control groups were 27.6%, 12.5%, and 43.75%, respectively. There was a statistically significant difference in the 5-FU and MMC groups when compared with the control group (chi-square; P = 0.04); however, the difference between the 5-FU and MMC groups was not significant. No serious complications were seen in the 5-FU and MMC groups. Conclusion: Intraoperative application of MMC and 5-FU is effective and safe for the prevention of recurrence. Our findings suggest that MMC is more potent for the prevention of recurrence and it causes less complaints than 5-FU.
MeSH term(s)	Fluorouracil ; Follow-Up Studies ; Humans ; Intraoperative Care ; Mitomycin ; Prospective Studies ; Pterygium ; Treatment Outcome
Chemical Substances	Mitomycin (50SG953SK6) ; Fluorouracil (U3P01618RT)
Language	English
Publishing date	2016-02-17
Publishing country	Turkey
Document type	Journal Article
ZDB-ID	1183461-4
ISSN	1303-6165 ; 1300-0144
ISSN (online)	1303-6165
ISSN	1300-0144
DOI	10.3906/sag-1408-32
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Article ; Online: RETRACTED: Azithromycin 1.5% Ophthalmic Solution for Blepharitis Treatment: Comparison of 14- Versus 30-Day Treatment.

Altay, Yesim / Demirok, Gulizar / Balta, Ozgur / Bolu, Hulya

publication RETRACTED

Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics

2017

Abstract: ... Treatment: Comparison of 14- Versus 30-Day Treatment," by Altay Yesim, Demirok Gulizar, Balta Ozgur, and ...

Abstract	The online-ahead-of-print published article, "Azithromycin 1.5% Ophthalmic Solution for Blepharitis Treatment: Comparison of 14- Versus 30-Day Treatment," by Altay Yesim, Demirok Gulizar, Balta Ozgur, and Bolu Hulya (DOI: 10.1089/jop.2015.0099) is being officially retracted from Journal of Ocular Pharmacology and Therapeutics (JOPT) due to post-publication authorship disputes and the discovery of simultaneous submission to both JOPT and the International Journal of Ophthalmology, which is a violation of the proper protocols of peer review. Journal of Ocular Pharmacology and Therapeutics and its editorial leadership are committed to maintaining the highest levels of scientific reporting and publishing, and therefore officially retracts the article based on the infringements listed herein.
Language	English
Publishing date	2017-06-05
Publishing country	United States
Document type	Retraction of Publication ; Retracted Publication
ZDB-ID	1237021-6
ISSN	1557-7732 ; 1080-7683
ISSN (online)	1557-7732
ISSN	1080-7683
DOI	10.1089/jop.2015.0099
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Zs.A 2099: Show issues

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Article: Amniotic membrane transplantation in bacterial and herpetic stromal keratitis.

Altay, Yeşim / Tamer, Sema / Burcu, Ayşe / Balta, Özgür

Turkish journal of medical sciences

2016 Volume 46, Issue 2, Page(s) 457–462

Abstract: Background/aim: The aim of this study was to describe the results of amniotic membrane transplantation (AMT) in patients with bacterial and herpetic stromal keratitis.: Materials and methods: This was a retrospective chart review study including 42 ... ...

Abstract	Background/aim: The aim of this study was to describe the results of amniotic membrane transplantation (AMT) in patients with bacterial and herpetic stromal keratitis. Materials and methods: This was a retrospective chart review study including 42 patients with herpetic keratitis (group 1) and 42 patients with bacterial keratitis (group 2). AMT was performed in addition to antimicrobial therapy. Topical steroids were administered after surgery. The outcome parameters evaluated were epithelialization time, decrease of stromal inflammation, and uncorrected visual acuity (UCVA). Results: The average age of our patients was 55.85 ± 19.07 years, and average follow-up was 14.70 ± 11.75 months. The period of epithelialization was 19.23 ± 7.32 days in the herpetic group and 19.31 ± 6.30 days in the bacterial group. Descemetocele developed in 2 patients of the herpetic group. Other patients in both groups completed epithelialization after AMT procedures with varying amounts of corneal scarring. The bacterial group showed an improvement in UCVA, but the herpetic group showed no improvement in UCVA. Conclusion: AMT is a convenient approach for the treatment of corneal keratitis resistant to conventional treatment and allows the use of early topical steroid application. It provides patients with corneal scarring an opportunity for subsequent keratoplasty by arresting the inflammatory response.
MeSH term(s)	Amnion ; Anti-Bacterial Agents ; Humans ; Keratitis, Herpetic ; Retrospective Studies ; Visual Acuity
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2016-02-17
Publishing country	Turkey
Document type	Journal Article
ZDB-ID	1183461-4
ISSN	1303-6165 ; 1300-0144
ISSN (online)	1303-6165
ISSN	1300-0144
DOI	10.3906/sag-1501-6
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Zs.A 3242: Show issues

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Article ; Online: Long-term results of cataract surgery in patients with anterior uveitis.

Balta, Ozgur / Sungur, Gulten / Acar, Mehmet Akif / Kosker, Mustafa / Yakin, Mehmet / Ornek, Firdevs

International ophthalmology

2018 Volume 38, Issue 4, Page(s) 1399–1407

Abstract: Purpose: This study was aimed to assess the long-term results of phacoemulsification and posterior chamber intraocular lens implantation in patients with anterior uveitis.: Methods: Patients with complicated cataract secondary to anterior uveitis who ...

Abstract	Purpose: This study was aimed to assess the long-term results of phacoemulsification and posterior chamber intraocular lens implantation in patients with anterior uveitis. Methods: Patients with complicated cataract secondary to anterior uveitis who underwent phacoemulsification and posterior chamber intraocular lens implantation were included in this study. Long-term results and all complications were evaluated throughout the postoperative 4 years. Results: A total of 55 eyes of 48 patients were identified in this study. Cases with anterior uveitis were categorised into four aetiologic groups. Of the 55 eyes, 22 (19 patients) had idiopathic anterior uveitis, 10 (9 patients) had viral anterior uveitis, 10 (9 patients) had Fuchs' anterior uveitis and 13 (11 patients) had anterior uveitis associated with collagen vascular diseases. Preoperative macular oedema was more frequent (63.6%) in the idiopathic group than in the other groups (p < 0.001). The success rates of the best corrected visual acuity of 20/40 or better ranged from 80.0 to 100.0% in the groups. While postoperative increased intraocular pressure rate was statistically significantly higher in the Fuchs' group (p = 0.047), there was no statistically significant difference in other complication rates between the groups. Conclusions: The long-term outcomes of phacoemulsification with intraocular lens implantation in patients with uveitic cataract were satisfactory with excellent visual acuity and relatively low complication rates.
MeSH term(s)	Adult ; Aged ; Cataract/diagnosis ; Cataract/etiology ; Female ; Follow-Up Studies ; Humans ; Lenses, Intraocular ; Male ; Middle Aged ; Phacoemulsification/methods ; Time Factors ; Treatment Outcome ; Uveitis, Anterior/complications ; Uveitis, Anterior/diagnosis ; Young Adult
Language	English
Publishing date	2018-08
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	800087-6
ISSN	1573-2630 ; 0165-5701
ISSN (online)	1573-2630
ISSN	0165-5701
DOI	10.1007/s10792-017-0598-z
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Zs.A 1479: Show issues

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Article ; Online: Clinical Features and Prognosis of Uveitis in a Turkish Patient Population with Ankylosing Spondylitis: Incidence and Management of Ocular Complications.

Sungur, Gulten / Yakin, Mehmet / Uzman, Selma / Balta, Ozgur / Orman, Gozde / Ornek, Firdevs

Ocular immunology and inflammation

2018 Volume 27, Issue 4, Page(s) 551–559

Abstract: ... ...

Abstract	Purpose
MeSH term(s)	Adolescent ; Adult ; Child ; Disease Management ; Fluorescein Angiography/methods ; Follow-Up Studies ; Fundus Oculi ; Humans ; Immunosuppressive Agents/therapeutic use ; Incidence ; Male ; Middle Aged ; Prognosis ; Retrospective Studies ; Spondylitis, Ankylosing/complications ; Spondylitis, Ankylosing/drug therapy ; Time Factors ; Tomography, Optical Coherence/methods ; Turkey/epidemiology ; Uveitis/diagnosis ; Uveitis/epidemiology ; Uveitis/etiology ; Visual Acuity ; Young Adult
Chemical Substances	Immunosuppressive Agents
Language	English
Publishing date	2018-02-23
Publishing country	England
Document type	Journal Article
ZDB-ID	1193873-0
ISSN	1744-5078 ; 0927-3948
ISSN (online)	1744-5078
ISSN	0927-3948
DOI	10.1080/09273948.2018.1431290
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Zs.A 4004: Show issues

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Article: Review of 306 evisceration surgeries performed between 2005 and 2013.

Balta, Özgür / Acar, Uğur / Akbaş Kocaoğlu, Fatma / Örnek, Firdevs

Turkish journal of medical sciences

2016 Volume 46, Issue 2, Page(s) 463–467

Abstract: Background/aim: The purpose of the present study was to evaluate the reasons for eye evisceration surgeries performed from 2005 to 2013 in our clinic.: Materials and methods: The medical records of patients who underwent evisceration surgery over the ...

Abstract	Background/aim: The purpose of the present study was to evaluate the reasons for eye evisceration surgeries performed from 2005 to 2013 in our clinic. Materials and methods: The medical records of patients who underwent evisceration surgery over the past 9 years were retrospectively evaluated. Detailed data were reviewed, with a focus on the first precipitating factor for evisceration. Results: Of the 306 patients who underwent evisceration surgery in the studied period, 111 (36.27%) were female (with a mean age of 41.56 ± 21.38 years) and 195 (63.73%) were male (with a mean age of 37.76 ± 21.92 years). The most common cause of evisceration was ocular trauma (184 patients; 60.1%). Male patients experienced significantly more trauma, while glaucoma was more common in female patients. Conclusions: Eye removal is devastating for both patients and their relatives, and its most important and preventable cause is ocular trauma.
MeSH term(s)	Adult ; Ambulatory Care Facilities ; Eye Enucleation ; Eye Evisceration ; Female ; Glaucoma ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Young Adult
Language	English
Publishing date	2016-02-17
Publishing country	Turkey
Document type	Journal Article
ZDB-ID	1183461-4
ISSN	1303-6165 ; 1300-0144
ISSN (online)	1303-6165
ISSN	1300-0144
DOI	10.3906/sag-1501-24
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Article ; Online: The outcome of penetrating keratoplasty for corneal scarring due to herpes simplex keratitis.

Altay, Yesim / Tamer, Sema / Kaya, Abdullah Sencer / Balta, Ozgur / Burcu, Ayse / Ornek, Firdevs

Arquivos brasileiros de oftalmologia

2017 Volume 80, Issue 1, Page(s) 41–45

Abstract: Purpose:: To determine the outcomes of penetrating keratoplasty (PK) for treatment of corneal scarring caused by Herpes simplex virus (HSV) keratitis, and whether the corneal scar type affects treatment outcome.: Methods:: A retrospective analysis of ...

Abstract	Purpose:: To determine the outcomes of penetrating keratoplasty (PK) for treatment of corneal scarring caused by Herpes simplex virus (HSV) keratitis, and whether the corneal scar type affects treatment outcome. Methods:: A retrospective analysis of patients who underwent PK for HSV-related corneal scarring between January 2008 and July 2011 was performed. The patients were categorized into two groups. Group 1 consisted of patients with a quiescent herpetic corneal scar and group 2 consisted of patients who developed a corneal descemetocele or perforation secondary to persistent epithelial defects with no active stromal inflammation. The mean follow-up was 21.30 ± 14.59 months. The main parameters evaluated were recurrence of herpetic keratitis, graft rejection, graft failure, visual acuity, and graft survival rate. Results:: There were 42 patients in group 1 and 13 in group 2. Preoperative BCVA varied from hand movements to 0.7 logMAR. Postoperatively, 34 patients (61.8%) achieved visual acuity of 0.6 logMAR or more. Recurrence of HSV keratitis was noted in 12 (28.57%) eyes in group 1 and 4 (30.76%) eyes in group 2 (p=0.40). Graft rejection occurred in 4 eyes (9.52%) in group 1 and in 3 (23.07%) eyes in group 2 (p=0.58). The 1-, 2-, and 3-year graft survival rates were 91.9%, 76.0%, and 65.1% in group 1, and 89.5%, 76.0%, and 63.6% in group 2 (p=0.91), respectively. Conclusions:: Although there were different recurrence and graft rejection rates for two groups, the graft survival rates at 3 years were similar. According to our results, without inflammation, corneal herpetic scarring with a descemetocele or perforation achieved similar graft survival rates with quiescent herpetic corneal scars.
MeSH term(s)	Acyclovir/therapeutic use ; Adult ; Antiviral Agents/therapeutic use ; Corneal Injuries/surgery ; Corneal Injuries/virology ; Female ; Graft Rejection ; Graft Survival ; Humans ; Keratitis, Herpetic/complications ; Keratitis, Herpetic/surgery ; Keratoplasty, Penetrating/methods ; Male ; Retrospective Studies ; Treatment Outcome ; Visual Acuity
Chemical Substances	Antiviral Agents ; Acyclovir (X4HES1O11F)
Language	English
Publishing date	2017-03-30
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	603915-7
ISSN	1678-2925 ; 0004-2749
ISSN (online)	1678-2925
ISSN	0004-2749
DOI	10.5935/0004-2749.20170011
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Article: Pattern Visual Evoked Potential Changes in Diabetic Patients without Retinopathy.

Balta, Ozgur / Sungur, Gulten / Yakin, Mehmet / Unlu, Nurten / Balta, Oyku Bezen / Ornek, Firdevs

Journal of ophthalmology

2017 Volume 2017, Page(s) 8597629

Abstract: Purpose. ...

Abstract	Purpose.
Language	English
Publishing date	2017-03-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	2546525-9
ISSN	2090-0058 ; 2090-004X
ISSN (online)	2090-0058
ISSN	2090-004X
DOI	10.1155/2017/8597629
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Article ; Online: Agreement between Corneal Thickness Measurements Using Pentacam Scheimpflug Camera, Noncontact Specular Microscopy, and Ultrasonographic Pachymetry in Diabetic Patients.

Altay, Yeşim / Balta, Ozgur / Demirok, Gülizar / Burcu, Ayse / Balta, Oyku Bezen / Ornek, Firdevs

Current eye research

2017 Volume 42, Issue 2, Page(s) 187–194

Abstract: Purpose: To evaluate the agreement of corneal thickness (CT) measurements obtained by the Pentacam Scheimpflug camera, noncontact specular microscopy (SM), and ultrasonographic pachymetry (UP) in diabetic (DM) patients; and whether duration of diabetes ... ...

Abstract	Purpose: To evaluate the agreement of corneal thickness (CT) measurements obtained by the Pentacam Scheimpflug camera, noncontact specular microscopy (SM), and ultrasonographic pachymetry (UP) in diabetic (DM) patients; and whether duration of diabetes and level of Hb A1c affect the agreement. Materials and methods: The CT was measured in 127 patients with DM, and 137 age and sex-matched healthy controls sequentially by Pentacam, SM, and UP. Also diabetic subjects were subdivided according to duration of diabetes and Hb A1c levels. Pearson correlation analysis, linear regression analysis, and Bland-Altman plots were used for examination of agreement. Results: We found an excellent and statistically significant correlation of CT measurements between Pentacam-SM (R Conclusion: SM-UP pair showed a higher agreement in diabetic patients. According to subgroup analyses, Hb A1c level, rather than the duration of diabetes, may determine the agreement of these pachymetry devices. But the difference in CT measurements between devices can still influence clinical diagnosis and treatment. Therefore, these methods are not completely interchangeable.
Language	English
Publishing date	2017-02
Publishing country	England
Document type	Journal Article
ZDB-ID	82079-9
ISSN	1460-2202 ; 0271-3683
ISSN (online)	1460-2202
ISSN	0271-3683
DOI	10.3109/02713683.2016.1170854
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Article ; Online: Short- to long-term results of Ahmed glaucoma valve in the management of elevated intraocular pressure in patients with pediatric uveitis.

Eksioglu, Umit / Yakin, Mehmet / Sungur, Gulten / Satana, Banu / Demirok, Gulizar / Balta, Ozgur / Ornek, Firdevs

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie

2017 Volume 52, Issue 3, Page(s) 295–301

Abstract: Objective: The aim of this study was to evaluate the long-term outcome of Ahmed glaucoma valve (AGV) implant for elevated intraocular pressure (IOP) in pediatric patients with uveitis.: Design: This was a retrospective chart review.: Participants: ...

Abstract	Objective: The aim of this study was to evaluate the long-term outcome of Ahmed glaucoma valve (AGV) implant for elevated intraocular pressure (IOP) in pediatric patients with uveitis. Design: This was a retrospective chart review. Participants: The study included 16 eyes (11 children) with uveitis. Methods: Success was defined as having IOP between 6 and 21 mm Hg with (qualified success) or without (complete success) antiglaucoma medications and without the need for further glaucoma or tube extraction surgery. Results: Mean age of patients at the time of AGV implantation was 14.19 ± 3.25 years. AGV implantation was the first glaucoma surgical procedure in 12 eyes (75%). Average postoperative follow-up period was 64.46 ± 33.56 months. Mean preoperative IOP was 33.50 ± 7.30 mm Hg versus 12.69 ± 3.20 mm Hg at the last follow-up visit (p < 0.001). Three eyes (18.7%) were determined as cases of "failure" because of tube removal in 2 eyes and a second AGV implantation in 1 eye. The cumulative probability of complete success was 68.8% at 6 months, 56.3% at 12 months, 49.2% at 36 months, 42.2% at 48 months, and 35.2% at 84 months, and the cumulative probability of eyes without complication was 75.0% at 6 months, 66.7% at 24 months, 58.3% at 36 months, 48.6% at 48 months and 24.3% at 108 months based on Kaplan-Meier survival analysis. Conclusions: Although AGV implant is an effective choice in the management of elevated IOP in pediatric uveitis, antiglaucoma medications are frequently needed for control of IOP. Tube exposure is an important complication in the long term. Differential diagnosis between relapse of uveitis and endophthalmitis is important in patients who received AGV implantation.
MeSH term(s)	Adolescent ; Child ; Child, Preschool ; Female ; Follow-Up Studies ; Glaucoma/complications ; Glaucoma/physiopathology ; Glaucoma/surgery ; Glaucoma Drainage Implants ; Humans ; Intraocular Pressure/physiology ; Male ; Retrospective Studies ; Time Factors ; Treatment Outcome ; Uveitis/complications ; Uveitis/therapy ; Visual Acuity
Language	English
Publishing date	2017-06
Publishing country	England
Document type	Journal Article
ZDB-ID	80091-0
ISSN	1715-3360 ; 0008-4182
ISSN (online)	1715-3360
ISSN	0008-4182
DOI	10.1016/j.jcjo.2016.11.015
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