LIVIVO - Search results -

Search results

Result 1 - 10 of total 184

Search options

Article: Achieving Commercial Applications for Microbial Biosurfactants.

Marchant, Roger / Banat, Ibrahim M

Advances in biochemical engineering/biotechnology

2022 Volume 181, Page(s) 181–193

Abstract: There are numerous biosurfactant producing strains and products reported annually most of which aspiring to potential future industrial and environmental applications. Only a few of these compounds have reached commercial applications due to many ... ...

Abstract	There are numerous biosurfactant producing strains and products reported annually most of which aspiring to potential future industrial and environmental applications. Only a few of these compounds have reached commercial applications due to many impediments to large-scale production and applications. We investigate some of the important criteria and investigations required to achieve such future commercial application.
MeSH term(s)	Surface-Active Agents
Chemical Substances	Surface-Active Agents
Language	English
Publishing date	2022-02-25
Publishing country	Germany
Document type	Journal Article
ISSN	0724-6145
ISSN	0724-6145
DOI	10.1007/10_2021_191
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article ; Online: Fungal bioproducts for petroleum hydrocarbons and toxic metals remediation: recent advances and emerging technologies

da Silva, André Felipe / Banat, Ibrahim M. / Robl, Diogo / Giachini, Admir José

Bioprocess Biosyst Eng. 2023 Mar., v. 46, no. 3 p.393-428

2023

Abstract: Petroleum hydrocarbons and toxic metals are sources of environmental contamination and are harmful to all ecosystems. Fungi have metabolic and morphological plasticity that turn them into potential prototypes for technological development in biological ... ...

Abstract	Petroleum hydrocarbons and toxic metals are sources of environmental contamination and are harmful to all ecosystems. Fungi have metabolic and morphological plasticity that turn them into potential prototypes for technological development in biological remediation of these contaminants due to their ability to interact with a specific contaminant and/or produced metabolites. Although fungal bioinoculants producing enzymes, biosurfactants, polymers, pigments and organic acids have potential to be protagonists in mycoremediation of hydrocarbons and toxic metals, they can still be only adjuvants together with bacteria, microalgae, plants or animals in such processes. However, the sudden accelerated development of emerging technologies related to the use of potential fungal bioproducts such as bioinoculants, enzymes and biosurfactants in the remediation of these contaminants, has boosted fungal bioprocesses to achieve higher performance and possible real application. In this review, we explore scientific and technological advances in bioprocesses related to the production and/or application of these potential fungal bioproducts when used in remediation of hydrocarbons and toxic metals from an integral perspective of biotechnological process development. In turn, it sheds light to overcome existing technological limitations or enable new experimental designs in the remediation of these and other emerging contaminants.
Keywords	biobased products ; bioprocessing ; biosurfactants ; fungi ; metabolites ; microalgae ; petroleum ; phenotypic plasticity ; pollution ; remediation ; toxicity
Language	English
Dates of publication	2023-03
Size	p. 393-428.
Publishing place	Springer Berlin Heidelberg
Document type	Article ; Online
ZDB-ID	1476357-6
ISSN	1432-0797 ; 1615-7605 ; 1615-7591
ISSN (online)	1432-0797 ; 1615-7605
ISSN	1615-7591
DOI	10.1007/s00449-022-02763-3
Database	NAL-Catalogue (AGRICOLA)

Order via subito

Article ; Online: Characterisation of cytotoxicity and immunomodulatory effects of glycolipid biosurfactants on human keratinocytes

Adu, Simms A. / Twigg, Matthew S. / Naughton, P. J. / Marchant, Roger / Banat, Ibrahim M.

Appl Microbiol Biotechnol. 2023 Jan., v. 107, no. 1 p.137-152

2023

Abstract: Skin irritation and allergic reactions associated with the use of skincare products formulated with synthetically derived surfactants such as sodium lauryl ether sulphate (SLES) have encouraged the search for naturally derived and biocompatible ... ...

Abstract	Skin irritation and allergic reactions associated with the use of skincare products formulated with synthetically derived surfactants such as sodium lauryl ether sulphate (SLES) have encouraged the search for naturally derived and biocompatible alternatives. Glycolipid biosurfactants such as sophorolipids (SL) and rhamnolipids (RL) offer a potential alternative to SLES. However, most studies on the bioactive properties of microbial glycolipids were determined using their mixed congeners, resulting in significant inter-study variations. This study aims to compare the effects of highly purified SL (acidic and lactonic) and RL (mono-RL and di-RL) congeners and SLES on a spontaneously transformed human keratinocyte cell line (HaCaT cells) to assess glycolipids’ safety for potential skincare applications. Preparations of acidic SL congeners were 100% pure, lactonic SL were 100% pure, mono-RL were 96% pure, and di-RL were 97% pure. Cell viability using XTT assays, cell morphological analyses, and immunoassays revealed that microbial glycolipids have differing effects on HaCaT cells dependent on chemical structure. Compared with SLES, acidic SL and mono-RL have negligible effects on cell viability, cell morphology, and production of pro-inflammatory cytokines. Furthermore, at non-inhibitory concentrations, di-RL significantly attenuated IL-8 production and CXCL8 expression while increasing IL-1RA production and IL1RN expression in lipopolysaccharide-stimulated HaCaT cells. Although further studies would be required, these results demonstrate that as potential innocuous and bioactive compounds, microbial glycolipids could provide a substitute to synthetic surfactants in skincare formulations and perform immunopharmacological roles in topical skin infections such as psoriasis. KEY POINTS: • Purified glycolipid congeners have differing effects on human keratinocytes. • Compared with SLES, acidic sophorolipids and mono-rhamnolipids have innocuous effects on keratinocytes. • Di-rhamnolipids and mono-rhamnolipids modulate cytokine production in lipopolysaccharide stimulated human keratinocytes.
Keywords	biosurfactants ; cell lines ; cell structures ; cell viability ; chemical structure ; cytotoxicity ; humans ; interleukin-8 ; keratinocytes ; lipopolysaccharides ; psoriasis ; rhamnolipids ; skin irritation ; sodium ; sophorolipids ; sulfates
Language	English
Dates of publication	2023-01
Size	p. 137-152.
Publishing place	Springer Berlin Heidelberg
Document type	Article ; Online
ZDB-ID	392453-1
ISSN	1432-0614 ; 0171-1741 ; 0175-7598
ISSN (online)	1432-0614
ISSN	0171-1741 ; 0175-7598
DOI	10.1007/s00253-022-12302-5
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Bonn / Germany

Z 79/727: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Glycolipid Biosurfactants in Skincare Applications: Challenges and Recommendations for Future Exploitation.

Adu, Simms A / Twigg, Matthew S / Naughton, Patrick J / Marchant, Roger / Banat, Ibrahim M

Molecules (Basel, Switzerland)

2023 Volume 28, Issue 11

Abstract: The 21st century has seen a substantial increase in the industrial applications of glycolipid biosurfactant technology. The market value of the glycolipid class of molecules, sophorolipids, was estimated to be USD 409.84 million in 2021, with that of ... ...

Abstract	The 21st century has seen a substantial increase in the industrial applications of glycolipid biosurfactant technology. The market value of the glycolipid class of molecules, sophorolipids, was estimated to be USD 409.84 million in 2021, with that of rhamnolipid molecules projected to reach USD 2.7 billion by 2026. In the skincare industry, sophorolipid and rhamnolipid biosurfactants have demonstrated the potential to offer a natural, sustainable, and skin-compatible alternative to synthetically derived surfactant compounds. However, there are still many barriers to the wide-scale market adoption of glycolipid technology. These barriers include low product yield (particularly for rhamnolipids) and potential pathogenicity of some native glycolipid-producing microorganisms. Additionally, the use of impure preparations and/or poorly characterised congeners as well as low-throughput methodologies in the safety and bioactivity assessment of sophorolipids and rhamnolipids challenges their increased utilisation in both academic research and skincare applications. This review considers the current trend towards the utilisation of sophorolipid and rhamnolipid biosurfactants as substitutes to synthetically derived surfactant molecules in skincare applications, the challenges associated with their application, and relevant solutions proposed by the biotechnology industry. In addition, we recommend experimental techniques/methodologies, which, if employed, could contribute significantly to increasing the acceptance of glycolipid biosurfactants for use in skincare applications while maintaining consistency in biosurfactant research outputs.
MeSH term(s)	Biotechnology/methods ; Surface-Active Agents ; Glycolipids ; Pulmonary Surfactants
Chemical Substances	Surface-Active Agents ; Glycolipids ; Pulmonary Surfactants
Language	English
Publishing date	2023-05-31
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	1413402-0
ISSN	1420-3049 ; 1431-5165 ; 1420-3049
ISSN (online)	1420-3049
ISSN	1431-5165 ; 1420-3049
DOI	10.3390/molecules28114463
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.MO 81: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Remediation Approaches to Reduce Hydrocarbon Contamination in Petroleum-Polluted Soil.

Elgazali, Abdelkareem / Althalb, Hakima / Elmusrati, Izzeddin / Ahmed, Hasna M / Banat, Ibrahim M

Microorganisms

2023 Volume 11, Issue 10

Abstract: Heavy metals pollution associated with oil spills has become a major concern worldwide. It is essential to break down these contaminants in the environment. In the environment, microbes have been used to detoxify and transform hazardous components. The ... ...

Abstract	Heavy metals pollution associated with oil spills has become a major concern worldwide. It is essential to break down these contaminants in the environment. In the environment, microbes have been used to detoxify and transform hazardous components. The process can function naturally or can be enhanced by adding nutrients, electron acceptors, or other factors. This study investigates some factors affecting hydrocarbon remediation technologies/approaches. Combinations of biological, chemical, and eco-toxicological techniques are used for this process while monitoring the efficacy of bacterial products and nutrient amendments to stimulate the biotransformation of contaminated soil. Different hydrocarbon removal levels were observed with bacterial augmentation (
Language	English
Publishing date	2023-10-17
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2720891-6
ISSN	2076-2607
ISSN	2076-2607
DOI	10.3390/microorganisms11102577
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Harnessing the Potential of Biosurfactants for Biomedical and Pharmaceutical Applications.

Ceresa, Chiara / Fracchia, Letizia / Sansotera, Andrea Chiara / De Rienzo, Mayri Alejandra Díaz / Banat, Ibrahim M

Pharmaceutics

2023 Volume 15, Issue 8

Abstract: Biosurfactants (BSs) are microbial compounds that have emerged as potential alternatives to chemical surfactants due to their multifunctional properties, sustainability and biodegradability. Owing to their amphipathic nature and distinctive structural ... ...

Abstract	Biosurfactants (BSs) are microbial compounds that have emerged as potential alternatives to chemical surfactants due to their multifunctional properties, sustainability and biodegradability. Owing to their amphipathic nature and distinctive structural arrangement, biosurfactants exhibit a range of physicochemical properties, including excellent surface activity, efficient critical micelle concentration, humectant properties, foaming and cleaning abilities and the capacity to form microemulsions. Furthermore, numerous biosurfactants display additional biological characteristics, such as antibacterial, antifungal and antiviral effects, and antioxidant, anticancer and immunomodulatory activities. Over the past two decades, numerous studies have explored their potential applications, including pharmaceuticals, cosmetics, antimicrobial and antibiofilm agents, wound healing, anticancer treatments, immune system modulators and drug/gene carriers. These applications are particularly important in addressing challenges such as antimicrobial resistance and biofilm formations in clinical, hygiene and therapeutic settings. They can also serve as coating agents for surfaces, enabling antiadhesive, suppression, or eradication strategies. Not least importantly, biosurfactants have shown compatibility with various drug formulations, including nanoparticles, liposomes, micro- and nanoemulsions and hydrogels, improving drug solubility, stability and bioavailability, and enabling a targeted and controlled drug release. These qualities make biosurfactants promising candidates for the development of next-generation antimicrobial, antibiofilm, anticancer, wound-healing, immunomodulating, drug or gene delivery agents, as well as adjuvants to other antibiotics. Analysing the most recent literature, this review aims to update the present understanding, highlight emerging trends, and identify promising directions and advancements in the utilization of biosurfactants within the pharmaceutical and biomedical fields.
Language	English
Publishing date	2023-08-18
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2527217-2
ISSN	1999-4923
ISSN	1999-4923
DOI	10.3390/pharmaceutics15082156
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: The role of surfactants and biosurfactants in the wound healing process: a review.

Ohadi, Mandana / Forootanfar, Hamid / Dehghannoudeh, Negar / Banat, Ibrahim M / Dehghannoudeh, Gholamreza

Journal of wound care

2023 Volume 32, Issue Sup4a, Page(s) xxxix–xlvi

Abstract: Wound healing refers to the complex process of restoring the forms and functions of damaged tissues. Multiple growth factors and released cytokines tightly regulate the wound site. Healing processes can be disrupted by any alteration that would aggravate ...

Abstract	Wound healing refers to the complex process of restoring the forms and functions of damaged tissues. Multiple growth factors and released cytokines tightly regulate the wound site. Healing processes can be disrupted by any alteration that would aggravate the damage and lengthen the repair process. Some of the conditions that may impair wound healing include infections and inflammation. Surfactants are amphiphilic compounds widely used in various formulations including detergents, food, pharmaceuticals and cosmetics. Biosurfactants, therefore, are surface-active compounds produced by biological agents, particularly yeast or bacteria, and represent a safer and environmentally preferred alternative to chemical surfactants. Numerous studies have targeted surface-active molecules as wound healing agents for their anti-inflammatory, antioxidant and antibacterial potential. This review focuses on surface-active molecules used in wound healing activities and analyses their effectiveness and mechanisms of action.
MeSH term(s)	Humans ; Surface-Active Agents/pharmacology ; Surface-Active Agents/therapeutic use ; Inflammation ; Antioxidants ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Wound Healing/physiology
Chemical Substances	Surface-Active Agents ; Antioxidants ; Anti-Bacterial Agents
Language	English
Publishing date	2023-04-04
Publishing country	England
Document type	Review ; Journal Article
ZDB-ID	1353951-6
ISSN	0969-0700
ISSN	0969-0700
DOI	10.12968/jowc.2023.32.Sup4a.xxxix
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 4572: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MG 4: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Microbial Biosurfactants: Antimicrobial Activity and Potential Biomedical and Therapeutic Exploits.

Puyol McKenna, Patricia / Naughton, Patrick J / Dooley, James S G / Ternan, Nigel G / Lemoine, Patrick / Banat, Ibrahim M

Pharmaceuticals (Basel, Switzerland)

2024 Volume 17, Issue 1

Abstract: The rapid emergence of multidrug-resistant pathogens worldwide has raised concerns regarding the effectiveness of conventional antibiotics. This can be observed in ESKAPE pathogens, among others, whose multiple resistance mechanisms have led to a ... ...

Abstract	The rapid emergence of multidrug-resistant pathogens worldwide has raised concerns regarding the effectiveness of conventional antibiotics. This can be observed in ESKAPE pathogens, among others, whose multiple resistance mechanisms have led to a reduction in effective treatment options. Innovative strategies aimed at mitigating the incidence of antibiotic-resistant pathogens encompass the potential use of biosurfactants. These surface-active agents comprise a group of unique amphiphilic molecules of microbial origin that are capable of interacting with the lipidic components of microorganisms. Biosurfactant interactions with different surfaces can affect their hydrophobic properties and as a result, their ability to alter microorganisms' adhesion abilities and consequent biofilm formation. Unlike synthetic surfactants, biosurfactants present low toxicity and high biodegradability and remain stable under temperature and pH extremes, making them potentially suitable for targeted use in medical and pharmaceutical applications. This review discusses the development of biosurfactants in biomedical and therapeutic uses as antimicrobial and antibiofilm agents, in addition to considering the potential synergistic effect of biosurfactants in combination with antibiotics. Furthermore, the anti-cancer and anti-viral potential of biosurfactants in relation to COVID-19 is also discussed.
Language	English
Publishing date	2024-01-22
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2193542-7
ISSN	1424-8247
ISSN	1424-8247
DOI	10.3390/ph17010138
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Optimization of fungal chitosan production from

Karamchandani, Bhoomika M / Maurya, Priya A / Awale, Manik / Dalvi, Sunil G / Banat, Ibrahim M / Satpute, Surekha K

3 Biotech

2024 Volume 14, Issue 3, Page(s) 82

Abstract: Fungal chitosan (FCH) is superior to crustacean chitosan (CH) sources and is of immense interest to the scientific community while having a high demand at the global market. Industrial scale fermentation technologies of FCH production are associated with ...

Abstract	Fungal chitosan (FCH) is superior to crustacean chitosan (CH) sources and is of immense interest to the scientific community while having a high demand at the global market. Industrial scale fermentation technologies of FCH production are associated with considerable challenges that frequently restrict their economic production and feasibility. The production of high quality FCH using an underexplored fungal strain Supplementary information: The online version contains supplementary material available at 10.1007/s13205-024-03919-6.
Language	English
Publishing date	2024-02-18
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2600522-0
ISSN	2190-5738 ; 2190-572X
ISSN (online)	2190-5738
ISSN	2190-572X
DOI	10.1007/s13205-024-03919-6
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Assessment of Rheological Behaviour of Water-in-Oil Emulsions Mediated by Glycolipid Biosurfactant Produced by Bacillus megaterium SPSW1001

Singh, Varsha / Waris, Zairah / Banat, Ibrahim M. / Saha, Sriparna / Padmanabhan, Padmini

Applied biochemistry and biotechnology. 2022 Mar., v. 194, no. 3

2022

Abstract: A screening programme using mineral salt medium supplemented with n-hexadecane resulted in isolating a Bacillus megaterium SPSW1001 which was capable of producing surface active molecules lowering culture medium surface tension to 27.43 ± 0.029 mN/m and ... ...

Abstract	A screening programme using mineral salt medium supplemented with n-hexadecane resulted in isolating a Bacillus megaterium SPSW1001 which was capable of producing surface active molecules lowering culture medium surface tension to 27.43 ± 0.029 mN/m and interfacial tension to 0.38 ± 0.03 mN/m at 72 h and an emulsification index (E₂₄) (85.63%). The biosurfactant product was further used to assess its effects on the rheological characteristics of water-in-oil emulsion prepared with engine oil. Structural characterization of the biosurfactant product by FTIR revealed a C–O–C stretch in sugar moiety and ester carbonyl linkage group between sugar and fatty acids, respectively, while mass spectral analysis revealed its glycolipid nature, with an m/z value of 662.44. The fluid behaviour of water-in-oil emulsion showed a non-Newtonian viscoelastic dilatant flow after yielding exemplified appropriately by Herschel-Bulkley model with 100% confidence of fit. The present study is significant in formulation and handling, processing, and transport of emulsion and in understanding flocculation characteristics.
Keywords	Bacillus megaterium ; biosurfactants ; biotechnology ; culture media ; emulsifying ; emulsions ; flocculation ; glycolipids ; hexadecane ; linkage groups ; models ; moieties ; oils ; spectral analysis ; sugars ; surface tension ; viscoelasticity
Language	English
Dates of publication	2022-03
Size	p. 1310-1326.
Publishing place	Springer US
Document type	Article
ZDB-ID	392344-7
ISSN	0273-2289
ISSN	0273-2289
DOI	10.1007/s12010-021-03717-3
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Bonn / Germany

Z 80/718: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED