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  1. Article: Extensive myocardial calcifications in a dialysis patient: A porcelain heart manifesting with abdominal pain.

    Rafiee, Moezedin Javad / Bandegi, Pouya / Taylor, Jana Lyn

    Radiology case reports

    2023  Volume 19, Issue 2, Page(s) 523–530

    Abstract: This case report describes a 41-year-old male patient with chronic kidney disease on peritoneal dialysis presenting with upper abdominal pain and mild thigh numbness. CT chest demonstrated extensive myocardial calcifications and left atrial thrombus. ... ...

    Abstract This case report describes a 41-year-old male patient with chronic kidney disease on peritoneal dialysis presenting with upper abdominal pain and mild thigh numbness. CT chest demonstrated extensive myocardial calcifications and left atrial thrombus. This case emphasizes the clinical relevance of myocardial calcifications, especially in patients with end-stage renal disease. It also highlights the potential association between these calcifications and complications such as atrial fibrillation and thromboembolic events. The findings emphasize the need for diagnostic vigilance and an improved understanding of the pathophysiology of myocardial calcifications in the context of renal disease.
    Language English
    Publishing date 2023-11-22
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2406300-9
    ISSN 1930-0433
    ISSN 1930-0433
    DOI 10.1016/j.radcr.2023.10.081
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Intussusception after colonoscopic polypectomy: a rare complication.

    Jastaniah, Atif / AlBusaidi, Nasra / Bandegi, Pouya / Grushka, Jeremy

    BMJ case reports

    2023  Volume 16, Issue 6

    Abstract: We present a patient who developed an ileocolic intussusception within a few hours of undergoing an endoscopic polypectomy found on screening colonoscopy. She underwent a laparoscopic right hemicolectomy with intracorporeal anastomosis. Final ... ...

    Abstract We present a patient who developed an ileocolic intussusception within a few hours of undergoing an endoscopic polypectomy found on screening colonoscopy. She underwent a laparoscopic right hemicolectomy with intracorporeal anastomosis. Final histopathological examination showed no evidence of malignancy. Intussusception after colonoscopy is a rare complication, and only 11 cases have been reported prior to this case. Laparoscopic resection with intracorporeal anastomosis is a safe and feasible option in patients who are not candidates or failed conservative management.
    MeSH term(s) Female ; Humans ; Intussusception/etiology ; Intussusception/surgery ; Intussusception/diagnosis ; Colectomy/adverse effects ; Colonoscopy/adverse effects ; Intestinal Polyps/surgery ; Intestinal Polyps/complications ; Laparoscopy/adverse effects ; Anastomosis, Surgical/adverse effects
    Language English
    Publishing date 2023-06-02
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2023-255048
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Superior Hypogastric Nerve Block as Post-Uterine Artery Embolization Analgesia: A Randomized and Double-Blind Clinical Trial.

    Yoon, Joongchul / Valenti, David / Muchantef, Karl / Cabrera, Tatiana / Toonsi, Fadi / Torres, Carlos / Bessissow, Ali / Bandegi, Pouya / Boucher, Louis-Martin

    Radiology

    2019  Volume 292, Issue 1, Page(s) 269

    Language English
    Publishing date 2019-06-20
    Publishing country United States
    Document type Journal Article ; Published Erratum
    ZDB-ID 80324-8
    ISSN 1527-1315 ; 0033-8419
    ISSN (online) 1527-1315
    ISSN 0033-8419
    DOI 10.1148/radiol.2019194008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Superior Hypogastric Nerve Block as Post-Uterine Artery Embolization Analgesia: A Randomized and Double-Blind Clinical Trial.

    Yoon, Joongchul / Valenti, David / Muchantef, Karl / Cabrera, Tatiana / Toonsi, Fadi / Torres, Carlos / Bessissow, Ali / Bandegi, Pouya / Boucher, Louis-Martin

    Radiology

    2018  Volume 289, Issue 1, Page(s) 248–254

    Abstract: Purpose To evaluate the effectiveness of superior hypogastric nerve block (SHNB) in reducing narcotic use after uterine artery embolization (UAE). Materials and Methods This study was a prospective, randomized, double-blind, parallel clinical trial in ... ...

    Abstract Purpose To evaluate the effectiveness of superior hypogastric nerve block (SHNB) in reducing narcotic use after uterine artery embolization (UAE). Materials and Methods This study was a prospective, randomized, double-blind, parallel clinical trial in patients referred to a tertiary care university teaching hospital for UAE. Forty-four participants were enrolled (mean age, 46 years; range, 32-56 years). No consenting patient was excluded. All participants were randomized 1:1 to undergo either a sham procedure or SHNB. There were 22 participants in each group. One participant was lost to follow-up regarding home survey results. Use of narcotics and antiemetics was recorded in-hospital. Pain scores were recorded at home for 10 days with use of a visual analog scale (range, 1-10). Statistical analysis was performed by using the t test and χ
    MeSH term(s) Adult ; Double-Blind Method ; Female ; Humans ; Leiomyoma/surgery ; Middle Aged ; Nerve Block/methods ; Pain, Postoperative/prevention & control ; Prospective Studies ; Treatment Outcome ; Uterine Artery Embolization/adverse effects ; Uterine Artery Embolization/methods ; Uterine Neoplasms/surgery
    Language English
    Publishing date 2018-07-10
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 80324-8
    ISSN 1527-1315 ; 0033-8419
    ISSN (online) 1527-1315
    ISSN 0033-8419
    DOI 10.1148/radiol.2018172714
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Intracellular mGluR5 plays a critical role in neuropathic pain.

    Vincent, Kathleen / Cornea, Virginia M / Jong, Yuh-Jiin I / Laferrière, André / Kumar, Naresh / Mickeviciute, Aiste / Fung, Jollee S T / Bandegi, Pouya / Ribeiro-da-Silva, Alfredo / O'Malley, Karen L / Coderre, Terence J

    Nature communications

    2016  Volume 7, Page(s) 10604

    Abstract: Spinal mGluR5 is a key mediator of neuroplasticity underlying persistent pain. Although brain mGluR5 is localized on cell surface and intracellular membranes, neither the presence nor physiological role of spinal intracellular mGluR5 is established. Here ...

    Abstract Spinal mGluR5 is a key mediator of neuroplasticity underlying persistent pain. Although brain mGluR5 is localized on cell surface and intracellular membranes, neither the presence nor physiological role of spinal intracellular mGluR5 is established. Here we show that in spinal dorsal horn neurons >80% of mGluR5 is intracellular, of which ∼60% is located on nuclear membranes, where activation leads to sustained Ca(2+) responses. Nerve injury inducing nociceptive hypersensitivity also increases the expression of nuclear mGluR5 and receptor-mediated phosphorylated-ERK1/2, Arc/Arg3.1 and c-fos. Spinal blockade of intracellular mGluR5 reduces neuropathic pain behaviours and signalling molecules, whereas blockade of cell-surface mGluR5 has little effect. Decreasing intracellular glutamate via blocking EAAT-3, mimics the effects of intracellular mGluR5 antagonism. These findings show a direct link between an intracellular GPCR and behavioural expression in vivo. Blockade of intracellular mGluR5 represents a new strategy for the development of effective therapies for persistent pain.
    MeSH term(s) Analgesics, Opioid/pharmacology ; Animals ; Behavior, Animal ; Blotting, Western ; Calcium/metabolism ; Cells, Cultured ; Cytoskeletal Proteins/metabolism ; Excitatory Amino Acid Transporter 3/antagonists & inhibitors ; Glutamic Acid/metabolism ; Glutamic Acid/pharmacology ; Hyperalgesia/metabolism ; Hyperalgesia/pathology ; Immunohistochemistry ; Injections, Spinal ; Male ; Microdialysis ; Microscopy, Confocal ; Microscopy, Electron ; Mitogen-Activated Protein Kinase 1/metabolism ; Mitogen-Activated Protein Kinase 3/metabolism ; Morphine/pharmacology ; Nerve Tissue Proteins/metabolism ; Neuralgia/metabolism ; Posterior Horn Cells/metabolism ; Posterior Horn Cells/pathology ; Proto-Oncogene Proteins c-fos/metabolism ; Proto-Oncogene Proteins c-jun/metabolism ; Rats ; Rats, Long-Evans ; Receptor, Metabotropic Glutamate 5/metabolism ; Sciatic Nerve/injuries ; Sciatic Neuropathy/metabolism ; Sciatic Neuropathy/pathology
    Chemical Substances Analgesics, Opioid ; Cytoskeletal Proteins ; Excitatory Amino Acid Transporter 3 ; Grm5 protein, rat ; Nerve Tissue Proteins ; Proto-Oncogene Proteins c-fos ; Proto-Oncogene Proteins c-jun ; Receptor, Metabotropic Glutamate 5 ; activity regulated cytoskeletal-associated protein ; Glutamic Acid (3KX376GY7L) ; Morphine (76I7G6D29C) ; Mitogen-Activated Protein Kinase 1 (EC 2.7.11.24) ; Mitogen-Activated Protein Kinase 3 (EC 2.7.11.24) ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2016-02-03
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/ncomms10604
    Database MEDical Literature Analysis and Retrieval System OnLINE

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