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  1. Article ; Online: Pharmaceutically active compounds in aqueous environment: recent developments in their fate, occurrence and elimination for efficient water purification.

    Bangia, Saulab / Bangia, Riya / Daverey, Achlesh

    Environmental monitoring and assessment

    2023  Volume 195, Issue 11, Page(s) 1344

    Abstract: The existence of pharmaceutically active compounds (PhACs) in the water is a major concern for environmentalists due to their deleterious effects on living organisms even at minuscule concentrations. This review focuses on PhACs such as analgesics and ... ...

    Abstract The existence of pharmaceutically active compounds (PhACs) in the water is a major concern for environmentalists due to their deleterious effects on living organisms even at minuscule concentrations. This review focuses on PhACs such as analgesics and anti-inflammatory compounds, which are massively excreted in urine and account for the majority of pharmaceutical pollution. Furthermore, other PhACs such as anti-epileptics, beta-blockers and antibiotics are discussed because they also contribute significantly to pharmaceutical pollution in the aquatic environment. This review is divided into two parts. In the first part, different classes of PhACs and their fate in the wastewater environment are presented. In the second part, recent advances in the removal of PhACs by conventional wastewater treatment plants, including membrane bioreactors (MBRs), activated carbon adsorption and bench-scale studies concerning a broad range of advanced oxidation processes (AOPs) that render practical and appropriate strategies for the complete mineralization and degradation of pharmaceutical drugs, are reviewed. This review indicates that drugs like diclofenac, naproxen, paracetamol and aspirin are removed efficiently by conventional systems. Activated carbon adsorption is suitable for the removal of diclofenac and carbamazepine, whereas AOPs are leading water treatment strategies for the effective removal of reviewed PhACs.
    MeSH term(s) Waste Disposal, Fluid ; Water Pollutants, Chemical/analysis ; Diclofenac ; Charcoal ; Environmental Monitoring ; Wastewater ; Water Purification ; Pharmaceutical Preparations
    Chemical Substances Water Pollutants, Chemical ; Diclofenac (144O8QL0L1) ; Charcoal (16291-96-6) ; Wastewater ; Pharmaceutical Preparations
    Language English
    Publishing date 2023-10-19
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 782621-7
    ISSN 1573-2959 ; 0167-6369
    ISSN (online) 1573-2959
    ISSN 0167-6369
    DOI 10.1007/s10661-023-11858-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Nanotechnological interventions in dermatophytosis: from oral to topical, a fresh perspective.

    Bangia, Riya / Sharma, Gajanand / Dogra, Sunil / Katare, Om Prakash

    Expert opinion on drug delivery

    2019  Volume 16, Issue 4, Page(s) 377–396

    Abstract: Introduction: The dermatophytosis are the infections, which are the most common infections worldwide, with the serious problem of high recurrence. These are characterized by invasion and multiplication of various species of dermatophytes in keratinized ... ...

    Abstract Introduction: The dermatophytosis are the infections, which are the most common infections worldwide, with the serious problem of high recurrence. These are characterized by invasion and multiplication of various species of dermatophytes in keratinized tissues that can affect skin, hair, and nails.
    Areas covered: This article aims to gather information about novel strategies for effective treatment of dermatophytosis by incorporating antifungals into nanoformulations to overcome the limitations of the conventional treatment strategies. Updates related to nanosystems and research progress regarding the animal and clinical studies are also included. The current treatment options for dermatophytosis, along with the marketed formulations and patents, are also highlighted.
    Expert opinion: For treating dermatophytosis, several therapeutic interventions are available which provide good clinical cure rates, but they have some demerits, including resistance to the antifungal agents and adverse effects associated with them. In recent years, efforts have been documented to incorporate various antifungal agents into novel carriers in order to offer better therapeutic action and overcome the limitations of the conventional treatment strategies for dermatophytosis. The success has been achieved in obtaining these formulations with enhanced antifungal activity, prolonged retention of drug, improved efficacy, increased skin penetration of the drug, and sustained release of drug.
    MeSH term(s) Animals ; Antifungal Agents/administration & dosage ; Drug Compounding ; Humans ; Nails/microbiology ; Nanostructures ; Skin/microbiology ; Tinea/drug therapy
    Chemical Substances Antifungal Agents
    Language English
    Publishing date 2019-04-03
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2167286-6
    ISSN 1744-7593 ; 1742-5247
    ISSN (online) 1744-7593
    ISSN 1742-5247
    DOI 10.1080/17425247.2019.1593962
    Database MEDical Literature Analysis and Retrieval System OnLINE

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