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Article: The Spectrum of COVID-19-Induced Liver Injury in Various Age and Risk Groups.

Bhusal, Tapasya / Banjade, Prakash / Surani, Salim / Sharma, Munish

2023 Volume 15, Issue 3, Page(s) e36349

Abstract: Coronavirus disease 2019 (COVID-19) has inflicted significant mortality and morbidity worldwide since the virus was first detected towards the end of 2019. Though it primarily affects the respiratory system, COVID-19 has been shown to have a multisystem ... ...

Abstract	Coronavirus disease 2019 (COVID-19) has inflicted significant mortality and morbidity worldwide since the virus was first detected towards the end of 2019. Though it primarily affects the respiratory system, COVID-19 has been shown to have a multisystem effect. There have been literature on liver injury associated with COVID-19 in general but liver injury specific to certain risk and age groups needs to be looked into. Thus, we aim to discuss the liver injury associated with COVID-19 in various age and risk groups and revisit pathophysiology, biochemical markers and their correlation with outcomes, and current management recommendations.
Language	English
Publishing date	2023-03-19
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.36349
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2023 Guidelines Reviewed.

Sharma, Munish / Joshi, Sushil / Banjade, Prakash / Ghamande, Shekhar A / Surani, Salim

The open respiratory medicine journal

2024 Volume 18, Page(s) e18743064279064

Abstract: The Global Initiative for Chronic Obstructive Lung Disease (GOLD) report is an essential resource for all clinicians who strive to provide optimal care to patients with chronic obstructive lung disease (COPD). The annual report of GOLD makes few ... ...

Abstract	The Global Initiative for Chronic Obstructive Lung Disease (GOLD) report is an essential resource for all clinicians who strive to provide optimal care to patients with chronic obstructive lung disease (COPD). The annual report of GOLD makes few revisions and updates besides including data from the preceding year. At an interval, GOLD comes up with a significant modification in its guidelines, which is generally a major overhaul of the pre-existing guidelines. According to the latest 2023 updates, published in November 2022, there have been significant advancements made in the field of COPD. These include the development of more precise definitions for COPD and its exacerbations, the introduction of a new set of parameters to measure exacerbation severity, and updating the COPD assessment tool. Additionally, revisions have been made to the initial and follow-up treatment guidelines. The report also simplifies the treatment algorithm and sheds light on new findings that suggest the use of pharmacological triple therapy can reduce mortality rates. Furthermore, the report includes discussions on inhaler device selection and adherence to COPD medications. These improvements demonstrate a continued effort to enhance COPD treatment and management. Although there are some areas that could benefit from more detailed guidance and explanation, such as the proper utilization of blood eosinophil counts for treatment decisions, and the establishment of treatment protocols post-hospitalization, the latest modifications to the GOLD recommendations will undoubtedly aid healthcare providers in addressing any gaps in patient care. We aim to highlight key changes in the GOLD 2023 report and present a viewpoint about their potential implications in a real-world clinical scenario.
Language	English
Publishing date	2024-01-10
Publishing country	United Arab Emirates
Document type	Journal Article ; Review
ZDB-ID	2395996-4
ISSN	1874-3064
ISSN	1874-3064
DOI	10.2174/0118743064279064231227070344
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Article: Systemic Venous Congestion Reviewed.

Banjade, Prakash / Subedi, Ashish / Ghamande, Shekhar / Surani, Salim / Sharma, Munish

Cureus

2023 Volume 15, Issue 8, Page(s) e43716

Abstract: Accurate determination of intravascular volume status is challenging in acutely ill patients. Favorable patient outcome is vital to correctly identify intravascular volume depletion and avoid systemic venous congestion. Most of the conventional means of ... ...

Abstract	Accurate determination of intravascular volume status is challenging in acutely ill patients. Favorable patient outcome is vital to correctly identify intravascular volume depletion and avoid systemic venous congestion. Most of the conventional means of hemodynamic monitoring in the acute healthcare setting are geared toward addressing the cardiac output and maintaining an optimum mean arterial pressure. While assessing and maintaining cardiac output in an acutely ill patient is very important, a venous congestion cascade is often overlooked, which can negatively affect the intraabdominal end organs. The prospect of using point-of-care ultrasound (POCUS) to determine systemic venous congestion could be a potentially handy tool for clinicians. Venous excess ultrasound score (VExUS) has also been utilized by clinicians as a semi-quantitative assessment tool to assess fluid status. This review aims to discuss the potential role of POCUS and VExUS scores in determining systemic venous congestion through a narrative review of recently published literature.
Language	English
Publishing date	2023-08-18
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.43716
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Updates on British Thoracic Society Statement on Pleural Disease and Procedures 2023.

Subedi, Ashish / Banjade, Prakash / Joshi, Sushil / Sharma, Munish / Surani, Salim

The open respiratory medicine journal

2023 Volume 17, Page(s) e18743064286775

Language	English
Publishing date	2023-12-01
Publishing country	United Arab Emirates
Document type	Journal Article
ZDB-ID	2395996-4
ISSN	1874-3064
ISSN	1874-3064
DOI	10.2174/0118743064286775231128104253
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Article ; Online: A Child Lost to Follow Up Carrying Beta Thalassemia Major: A Case Report.

Banjade, Prakash / Bhandari, Jeetendra

JNMA; journal of the Nepal Medical Association

2020 Volume 58, Issue 226, Page(s) 436–438

Abstract: Thalassemia is inherited autosomal recessive disorders characterized by reduced rate of hemoglobin synthesis due to a defect in alpha or beta globin chain synthesis. Maldives has a beta thalassemia prevalence rate of 16-18%. Classical symptoms of beta ... ...

Abstract	Thalassemia is inherited autosomal recessive disorders characterized by reduced rate of hemoglobin synthesis due to a defect in alpha or beta globin chain synthesis. Maldives has a beta thalassemia prevalence rate of 16-18%. Classical symptoms of beta thalassemia are common on those patients who present late for blood transfusion which is common among the south Asian countries due to resource poor situation. This case is a rare case report of commonly occurring phenomenon which has been reported less among south Asian region. Reporting this case will help health worker to manage cases accordingly. A five and half year prior diagnosed case of beta thalassemia at age of 2 years and lost to follow up presented with cough, Dyspnoea, Irritability, fatigue with classic symptom of beta thalassemia. She was managed with blood transfusion and kept on continuous follow up for transfusion and iron overload management.
MeSH term(s)	Blood Transfusion ; Child, Preschool ; Female ; Humans ; Lost to Follow-Up ; beta-Thalassemia/complications ; beta-Thalassemia/diagnosis ; beta-Thalassemia/therapy
Language	English
Publishing date	2020-06-30
Publishing country	Nepal
Document type	Case Reports ; Journal Article
ZDB-ID	2209910-4
ISSN	1815-672X ; 0028-2715
ISSN (online)	1815-672X
ISSN	0028-2715
DOI	10.31729/jnma.5129
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Article: An Infrequently Encountered Cause of Hemoptysis.

Banjade, Prakash / Rijal, Yasoda / Itani, Asmita / Lou, Becky X / Sharma, Munish

Cureus

2023 Volume 15, Issue 9, Page(s) e45954

Abstract: Mitral stenosis (MS) is not a common entity in modern-day medicine, especially in developed countries, as the most common etiology is still rheumatic fever. MS can present mainly with a wide range of cardiac symptoms. However, infrequently, MS can cause ... ...

Abstract	Mitral stenosis (MS) is not a common entity in modern-day medicine, especially in developed countries, as the most common etiology is still rheumatic fever. MS can present mainly with a wide range of cardiac symptoms. However, infrequently, MS can cause extra-cardiac symptoms as well. We present a case report of a patient with severe bioprosthetic mitral valve stenosis with intermittent hemoptysis and cardiogenic shock. We aim to report this case to remind clinicians about this uncommon but significant cause of hemoptysis. This case report also emphasizes the importance of utilizing a team approach while treating patients with severe MS, especially if they have serious complications that could be life-threatening. We also aim to add to the current literature by reporting this case.
Language	English
Publishing date	2023-09-25
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.45954
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Article: Atypical Kawasaki Disease in a 4 Years Old Child with Mumps.

Banjade, Prakash / Subedi, Kiran

JNMA; journal of the Nepal Medical Association

2018 Volume 56, Issue 212, Page(s) 811–814

Abstract: Kawasaki disease is an acute febrile condition seen in children. However, it is also well recognized that some patients do not fulfill the classic diagnostic criteria for the diagnosis of Kawasaki disease. The incomplete form of Kawasaki disease is ... ...

Abstract	Kawasaki disease is an acute febrile condition seen in children. However, it is also well recognized that some patients do not fulfill the classic diagnostic criteria for the diagnosis of Kawasaki disease. The incomplete form of Kawasaki disease is termed as 'Incomplete KD' or 'Atypical KD'. This is a case of 4 years old child with fever and mumps. He had bilateral cervical adenitis. Patient failed to respond to IV antibiotics fulfilled the criteria of incomplete Kawasaki disease. The child was managed with high dose aspirin until the child was afebrile for 48 hours. Kawasaki disease is a common vasculitis in children. Atypical cases might be missed if there is concomitant viral illness. Hence the identification and management of Kawasaki disease is paramount to decrease the mortality related to the cardiac disease. Keywords: bilateral cervical adenitis; fever and mumps; failed to respond IV antibiotics; incomplete kawasaki disease.
MeSH term(s)	Child, Preschool ; Echocardiography ; Humans ; Male ; Mucocutaneous Lymph Node Syndrome/complications ; Mucocutaneous Lymph Node Syndrome/diagnosis ; Mucocutaneous Lymph Node Syndrome/diagnostic imaging ; Mucocutaneous Lymph Node Syndrome/pathology ; Mumps/complications
Language	English
Publishing date	2018-12-21
Publishing country	Nepal
Document type	Case Reports ; Journal Article
ZDB-ID	2209910-4
ISSN	1815-672X ; 0028-2715
ISSN (online)	1815-672X
ISSN	0028-2715
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Article ; Online: Acute Stroke in Tubercular Meningitis: A Case Report.

Bhusal, Suzit / Dahal, Sujata / Gautam, Neha / Banjade, Prakash

JNMA; journal of the Nepal Medical Association

2020 Volume 57, Issue 219, Page(s) 385–387

Abstract: Most of the strokes in tubercular meningitis are multiple, bilateral, and located in the basal ganglia, especially the 'tubercular zone', which comprises of the caudate, anterior thalamus, anterior limb, and genu of the internal capsule. These are ... ...

Abstract	Most of the strokes in tubercular meningitis are multiple, bilateral, and located in the basal ganglia, especially the 'tubercular zone', which comprises of the caudate, anterior thalamus, anterior limb, and genu of the internal capsule. These are attributed to the involvement of medial striate, thalamotuberal, and thalamostriate arteries, which are embedded in exudates and likely to be stretched by coexistent hydrocephalus. Corticosteroids with antitubercular therapy were thought to reduce mortality and morbidity but their role in lowering strokes has not been proven. The mechanism of stroke in our case was vasculitis. Here, we are reporting a case of 22-years female patient with tubercular meningitis. She had complications of ischemic infarct and severe communicating hydrocephalus with a seizure disorder. Keywords: meningeal tuberculosis; stroke; tuberculoma; vasculitis.
MeSH term(s)	Brain Ischemia/diagnosis ; Brain Ischemia/etiology ; Cerebral Infarction/diagnosis ; Cerebral Infarction/etiology ; Epilepsy/diagnosis ; Epilepsy/etiology ; Female ; Humans ; Hydrocephalus/diagnosis ; Hydrocephalus/etiology ; Stroke/diagnosis ; Stroke/etiology ; Tuberculosis, Meningeal/complications ; Tuberculosis, Meningeal/diagnosis ; Young Adult
Language	English
Publishing date	2020-07-28
Publishing country	Nepal
Document type	Case Reports ; Journal Article
ZDB-ID	2209910-4
ISSN	1815-672X ; 0028-2715
ISSN (online)	1815-672X
ISSN	0028-2715
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Article ; Online: Sarcomatoid Carcinoma of Orbit in a Patient With Xeroderma Pigmentosum.

Banjade, Prakash / Itani, Asmita / Kandel, Kamal / Acharya, Shradha / Sharma, Munish / Shrestha, Gulshan Bahadur / Surani, Salim

Journal of medical cases

2023 Volume 14, Issue 6, Page(s) 191–195

Abstract: Spindle cell carcinoma (SpCC), also referred to as sarcomatoid carcinoma, makes up less than 3% of all head and neck squamous cell carcinomas (SCCs). It is an uncommon and unusual biphasic malignant tumor primarily affecting the upper aero-digestive ... ...

Abstract	Spindle cell carcinoma (SpCC), also referred to as sarcomatoid carcinoma, makes up less than 3% of all head and neck squamous cell carcinomas (SCCs). It is an uncommon and unusual biphasic malignant tumor primarily affecting the upper aero-digestive tract. SpCC consists of spindled or pleomorphic tumor cells. Mostly, these tumors are seen in the fifth or sixth decades of life and are strongly associated with smoking and alcohol. We hereby report an infrequently encountered case of SpCC in a patient with xeroderma pigmentosum (XP), who was young, nonsmoker, and did not consume alcohol. The mass arose from the right orbit and involved the entire right face. The postoperative histopathological report showed SpCC. Surgical excision of the mass was performed. We aimed to add to the prevailing literature by reporting this case.
Language	English
Publishing date	2023-06-29
Publishing country	Canada
Document type	Case Reports
ZDB-ID	2586383-6
ISSN	1923-4163 ; 1923-4163
ISSN (online)	1923-4163
ISSN	1923-4163
DOI	10.14740/jmc4110
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Article ; Online: Anaemia among Third-trimester Pregnant Women in a Community Hospital: A Descriptive Cross-sectional Study.

Kandel, Kamal / Paudel, Bhavana / Gauchan, Eva / Adhikari, Suraj / Khadka, Nisha / Chaulagain, Prashant / Banjade, Prakash / Paudel, Ananta Hari

JNMA; journal of the Nepal Medical Association

2023 Volume 61, Issue 257, Page(s) 36–38

Abstract: Introduction: Anaemia has haemoglobin levels of less than 11/100 ml in the first and third trimesters and less than 10/100 ml in the second. Maternal anaemia is a global health issue that has a negative impact on neonatal outcomes. The prevalence is ... ...

Abstract	Introduction: Anaemia has haemoglobin levels of less than 11/100 ml in the first and third trimesters and less than 10/100 ml in the second. Maternal anaemia is a global health issue that has a negative impact on neonatal outcomes. The prevalence is more common in developing nations like Nepal. Positive correlations have been found between third-trimester maternal haemoglobin and neonatal birth weight. Our study aimed to find out the prevalence of anaemia among third-trimester of pregnant women in a community hospital. Methods: This was a descriptive cross-sectional study conducted in the outpatient Department of Obstetrics and Gynecology from September 2020 to September 2021. Ethical approval was taken from the Nepal health research council (Registration number: 577/2020P). The haemoglobin level of 375 participants was recorded. Data were analyzed using Statistical package for social sciences (SPSS) version 22. Convenience sampling was used. Point estimate and 95% Confidence Interval were calculated. Results: Out of a total of 375 pregnant females in the third trimester, 31 (8.27%) (5.48-11.06, 95% Confidence Interval) were anaemia. Conclusions: The prevalence of anaemia was lower as compared to other studies done in similar settings. Keywords: anemia; maternal-child health services; prevalence.
MeSH term(s)	Infant, Newborn ; Pregnancy ; Female ; Humans ; Pregnancy Trimester, Third ; Pregnant Women ; Cross-Sectional Studies ; Pregnancy Complications, Hematologic/epidemiology ; Hospitals, Community ; Anemia/epidemiology ; Hemoglobins/analysis ; Prevalence
Chemical Substances	Hemoglobins
Language	English
Publishing date	2023-01-01
Publishing country	Nepal
Document type	Journal Article
ZDB-ID	2209910-4
ISSN	1815-672X ; 0028-2715
ISSN (online)	1815-672X
ISSN	0028-2715
DOI	10.31729/jnma.7844
Database	MEDical Literature Analysis and Retrieval System OnLINE

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