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  1. Article ; Online: Spatiotemporal Evolution of SARS-CoV-2 Alpha and Delta Variants during Large Nationwide Outbreak of COVID-19, Vietnam, 2021.

    Tam, Nguyen Thi / Anh, Nguyen To / Tung, Trinh Son / Thach, Pham Ngoc / Dung, Nguyen Thanh / Trang, Van Dinh / Hung, Le Manh / Dien, Trinh Cong / Ngoc, Nghiem My / Van Duyet, Le / Cuong, Phan Manh / Phuong, Hoang Vu Mai / Thai, Pham Quang / Tung, Nguyen Le Nhu / Man, Dinh Nguyen Huy / Phong, Nguyen Thanh / Quang, Vo Minh / Thoa, Pham Thi Ngoc / Truong, Nguyen Thanh /
    Thao, Tran Nguyen Phuong / Linh, Dao Phuong / Tai, Ngo Tan / Bao, Ho The / Vuong, Vo Trong / Nhung, Huynh Thi Kim / Hong, Phan Nu Dieu / Hanh, Le Thi Phuoc / Chung, Le Thanh / Nhan, Nguyen Thi Thanh / Thanh, Ton That / Hung, Do Thai / Mai, Huynh Kim / Long, Trinh Hoang / Trang, Nguyen Thu / Thuong, Nguyen Thi Hong / Hong, Nguyen Thi Thu / Nhu, Le Nguyen Truc / Ny, Nguyen Thi Han / Thuy, Cao Thu / Thanh, Le Kim / Nguyet, Lam Anh / Mai, Le Thi Quynh / Thuong, Tang Chi / Nga, Le Hong / Thanh, Tran Tan / Thwaites, Guy / Rogier van Doorn, H / Chau, Nguyen Van Vinh / Kesteman, Thomas / Van Tan, Le

    Emerging infectious diseases

    2023  Volume 29, Issue 5, Page(s) 1002–1006

    Abstract: We analyzed 1,303 SARS-CoV-2 whole-genome sequences from Vietnam, and found the Alpha and Delta variants were responsible for a large nationwide outbreak of COVID-19 in 2021. The Delta variant was confined to the AY.57 lineage and caused >1.7 million ... ...

    Abstract We analyzed 1,303 SARS-CoV-2 whole-genome sequences from Vietnam, and found the Alpha and Delta variants were responsible for a large nationwide outbreak of COVID-19 in 2021. The Delta variant was confined to the AY.57 lineage and caused >1.7 million infections and >32,000 deaths. Viral transmission was strongly affected by nonpharmaceutical interventions.
    MeSH term(s) Humans ; COVID-19/epidemiology ; SARS-CoV-2/genetics ; Vietnam/epidemiology ; Disease Outbreaks
    Language English
    Publishing date 2023-04-04
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1380686-5
    ISSN 1080-6059 ; 1080-6040
    ISSN (online) 1080-6059
    ISSN 1080-6040
    DOI 10.3201/eid2905.221787
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: An observational study of breakthrough SARS-CoV-2 Delta variant infections among vaccinated healthcare workers in Vietnam.

    Chau, Nguyen Van Vinh / Ngoc, Nghiem My / Nguyet, Lam Anh / Quang, Vo Minh / Ny, Nguyen Thi Han / Khoa, Dao Bach / Phong, Nguyen Thanh / Toan, Le Mau / Hong, Nguyen Thi Thu / Tuyen, Nguyen Thi Kim / Phat, Voong Vinh / Nhu, Le Nguyen Truc / Truc, Nguyen Huynh Thanh / That, Bui Thi Ton / Thao, Huynh Phuong / Thao, Tran Nguyen Phuong / Vuong, Vo Trong / Tam, Tran Thi Thanh / Tai, Ngo Tan /
    Bao, Ho The / Nhung, Huynh Thi Kim / Minh, Nguyen Thi Ngoc / Tien, Nguyen Thi My / Huy, Nguy Cam / Choisy, Marc / Man, Dinh Nguyen Huy / Ty, Dinh Thi Bich / Anh, Nguyen To / Uyen, Le Thi Tam / Tu, Tran Nguyen Hoang / Yen, Lam Minh / Dung, Nguyen Thanh / Hung, Le Manh / Truong, Nguyen Thanh / Thanh, Tran Tan / Thwaites, Guy / Tan, Le Van

    EClinicalMedicine

    2021  Volume 41, Page(s) 101143

    Abstract: Background: Data on breakthrough SARS-CoV-2 Delta variant infections in vaccinated individuals are limited.: Methods: We studied breakthrough infections among Oxford-AstraZeneca vaccinated healthcare workers in an infectious diseases hospital in ... ...

    Abstract Background: Data on breakthrough SARS-CoV-2 Delta variant infections in vaccinated individuals are limited.
    Methods: We studied breakthrough infections among Oxford-AstraZeneca vaccinated healthcare workers in an infectious diseases hospital in Vietnam. We collected demographic and clinical data alongside serial PCR testing, measurement of SARS-CoV-2 antibodies, and viral whole-genome sequencing.
    Findings: Between 11
    Interpretation: Breakthrough Delta variant infections following Oxford-AstraZeneca vaccination may cause asymptomatic or mild disease, but are associated with high viral loads, prolonged PCR positivity and low levels of vaccine-induced neutralizing antibodies. Epidemiological and sequence data suggested ongoing transmission had occurred between fully vaccinated individuals.
    Funding: Wellcome and NIH/NIAID.
    Language English
    Publishing date 2021-09-30
    Publishing country England
    Document type Journal Article
    ISSN 2589-5370
    ISSN (online) 2589-5370
    DOI 10.1016/j.eclinm.2021.101143
    Database MEDical Literature Analysis and Retrieval System OnLINE

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