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Article: A comparison between the preferences for oral corrective feedback of teachers and students of Chinese as a second language.

Bao, Rui / Wang, Hui

2023 Volume 14, Page(s) 1112136

Abstract: This study reports on the preferences of teachers and students of Chinese as a second language (CSL) for corrective feedback ( ...

Abstract	This study reports on the preferences of teachers and students of Chinese as a second language (CSL) for corrective feedback (
Language	English
Publishing date	2023-03-09
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2563826-9
ISSN	1664-1078
ISSN	1664-1078
DOI	10.3389/fpsyg.2023.1112136
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: 轮虫生态毒理学测试指标的敏感性研究进展.

Zhang, Gen / Chen, Bao-Rui

Ying yong sheng tai xue bao = The journal of applied ecology

2022 Volume 33, Issue 3, Page(s) 855–864

Abstract: Human activities have severely polluted environments during industrialization. Rotifers are commonly used as model species for ecotoxicological assays. The sensitivities of ecotoxicological indices of rotifers highly depend on different pollutants. We ... ...

Title translation	Research progress on sensitivity of indices for ecotoxicological assays using rotifers.
Abstract	Human activities have severely polluted environments during industrialization. Rotifers are commonly used as model species for ecotoxicological assays. The sensitivities of ecotoxicological indices of rotifers highly depend on different pollutants. We summarized available ecotoxicological indices of rotifers, and reviewed their sensitivity to commonly investigated pollutants. Under the stress of heavy metals, the life-table demographic parameters, physiological and biochemical indices generally show high sensitivity. In response to persistent organic pollutants, sexual indices generally show higher sensitivity than asexual ones. Some studies showed that swimming speed revealed higher sensitivity after exposure to several pollutants compared with life-table demographic and population growth indices. We suggested to consider swimming speed of rotifer as an alternative index for ecotoxicological assays. Overall, this study would provide a guideline for rotifer ecotoxicological studies in the future.
MeSH term(s)	Animals ; Ecotoxicology ; Humans ; Metals, Heavy ; Rotifera/physiology ; Swimming ; Water Pollutants, Chemical/toxicity
Chemical Substances	Metals, Heavy ; Water Pollutants, Chemical
Language	Chinese
Publishing date	2022-05-07
Publishing country	China
Document type	Journal Article
ZDB-ID	2881809-X
ISSN	1001-9332
ISSN	1001-9332
DOI	10.13287/j.1001-9332.202206.028
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: How does government attention matter in air pollution control? Evidence from government annual reports

Bao, Rui / Liu, Tianle

Resources, conservation, and recycling. 2022 Oct., v. 185

2022

Abstract: Ambitious environmental action demands policymakers' attention. Since 2014, when China proclaimed a "war on pollution," government attention to environmental concerns has increased unprecedentedly. The purpose of this study is to determine empirically if, ...

Abstract	Ambitious environmental action demands policymakers' attention. Since 2014, when China proclaimed a "war on pollution," government attention to environmental concerns has increased unprecedentedly. The purpose of this study is to determine empirically if, and to what extent, this government attention has had an effect on environmental quality, particularly local air pollution. We quantified local Chinese governments' attention to the environment from 2014 to 2019 using a dataset of the textual content of their Government Annual Reports (GARs) from 286 cities at or above prefectural level (APL). The Spatial Durbin Model (SDM) is selected as the most probable spatial econometric model using Bayesian posterior model probabilities. As demonstrated, environmental attention is related with perceptible increases in air quality. On average, a one-unit increase in environmental attention resulted with decreases of 4.2 %, 4.5 %, and 7.4 % in AQI index, PM₁₀, and NO₂ concentrations, respectively. As an auxiliary validation, we found evidence at provincial level that environmental agenda and investment in pollution control represent the primary outputs of increased environmental attention. A further analysis by subsample revealed that the effect of environmental attention on air pollution differed by region. In general, this study establishes a compelling rationale for municipal governments to prioritize environmental issues and devote additional attention and resources to pollution control.
Keywords	Bayesian theory ; air pollution ; air pollution control ; air quality ; data collection ; econometric models ; China
Language	English
Dates of publication	2022-10
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	1498716-8
ISSN	0921-3449
ISSN	0921-3449
DOI	10.1016/j.resconrec.2022.106435
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: A study of the effect of changes in nasal tip prominence on the sense of anterior prominence of the upper lip

ZHUANG Ziting / BAO Rui / LI Menghuan / WANG Weicai / BAO Baicheng

口腔疾病防治, Vol 31, Iss 5, Pp 345-

2023 Volume 351

Abstract: Objective The aim of this study was to investigate the effect of changes in nasal tip protrusion on the sense of upper lip protrusion in different populations and to provide a reference for the improvement of soft tissue beauty. Methods Informed consent ... ...

Abstract	Objective The aim of this study was to investigate the effect of changes in nasal tip protrusion on the sense of upper lip protrusion in different populations and to provide a reference for the improvement of soft tissue beauty. Methods Informed consent and portrait authorization were obtained from the model. A female model whose face met the criteria was selected, and a 3D model of her was obtained using a 3D stereo camera. Based on the original model, ZBRUSH2019 software was used to simulate changes in nose tip protrusion. Then, 9 segments of facial dynamic rotation videos were produced, and an electronic questionnaire was created through a questionnaire website to evaluate the effect of different nose tip protrusions on perceived upper lip protrusion. Randomly selected orthodontic patients, orthodontics professionals and general adults completed the electronic questionnaire. In the questionnaire, a Visual Analog Scale was used to evaluate the perceived degree of protrusion of the upper lip. The higher the score, the more prominent the upper lip of the model in the image. The questionnaire data were statistically analyzed using a generalized linear mixed model. Results As the nasal tip position became progressively more retracted, the subjects' upper lip protrusion scores increased. Among male subjects, the results showed that the general population thought that the upper lip protrusion was higher than the patients did when the nasal tip protrusion was +6 mm and +4.5 mm (P = 0.023, P = 0.047). When the nasal tip protrusion was +6 mm, the scores of the general population were higher than those of the orthodontics professionals (P = 0.023). However, when the nasal tip variable was -6 mm, their score was lower than that of the patients (P = 0.003), and there was no significant difference in other retest distances between groups (P>0.05). Conclusion When the protrusion of the nasal tip decreased, the three groups experienced a visual illusion of upper lip protrusion. When the nasal tip protrusion is too large, ...
Keywords	orthodontics ; dental ; facial aesthetics ; visual illusion ; 3dmd ; 3d image ; nasal tip prominence ; lip protrusion ; Medicine ; R
Subject code	150
Language	Chinese
Publishing date	2023-05-01T00:00:00Z
Publisher	Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Does China's residential mobility reduce fertility intentions? The mediating role of well-being.

Xiao, Xi-Dan / Chang, Bao-Rui / Lian, Rong

Acta psychologica

2023 Volume 241, Page(s) 104082

Abstract: With declining fertility rates becoming a global trend, it is crucial to enhance the fertility intentions of mobile individuals of reproductive age. This study utilizes both questionnaire surveys and experimental methods to examine the influence of ... ...

Abstract	With declining fertility rates becoming a global trend, it is crucial to enhance the fertility intentions of mobile individuals of reproductive age. This study utilizes both questionnaire surveys and experimental methods to examine the influence of residential mobility on fertility intentions and the mediating role of well-being. The consistent findings from Study 1 and Study 2 (2a and 2b) indicate that residential mobility significantly negatively predicts individuals' fertility intentions, and well-being plays a significant mediating role between residential mobility and fertility intentions. This research, conducted from a psychological perspective, sheds light on the internal mechanisms linking residential mobility and fertility intentions, providing theoretical and empirical evidence to enhance fertility intentions among mobile populations in China.
MeSH term(s)	Humans ; Intention ; Population Dynamics ; Fertility ; Birth Rate ; China
Language	English
Publishing date	2023-11-09
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1480049-4
ISSN	1873-6297 ; 0001-6918
ISSN (online)	1873-6297
ISSN	0001-6918
DOI	10.1016/j.actpsy.2023.104082
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Comparative analysis of five type II TA systems identified in

Song, Yingjie / Tang, Hong / Bao, Rui

Frontiers in cellular and infection microbiology

2023 Volume 13, Page(s) 1127786

Abstract: Background: Pseudomonas aeruginosa: Methods: We here investigated the diversity and function of five genomic type II TA systems widely distributed among : Results: ParDE, PA1030/PA1029, and HigBA could modulate persister cell formation under ... ...

Abstract	Background: Pseudomonas aeruginosa Methods: We here investigated the diversity and function of five genomic type II TA systems widely distributed among Results: ParDE, PA1030/PA1029, and HigBA could modulate persister cell formation under treatment with specific antibiotics. Furthermore, cell-based transcriptional and invasion assays revealed that PA1030/PA1029 and HigBA TA systems were critical for intracellular survival. Discussion: Our results highlight the prevalence and diverse roles of type II TA systems in
MeSH term(s)	Humans ; Pseudomonas aeruginosa/metabolism ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/metabolism ; Lung/metabolism ; Bacterial Toxins/genetics ; Bacterial Toxins/metabolism ; Toxin-Antitoxin Systems/genetics ; Pseudomonas Infections/microbiology
Chemical Substances	Anti-Bacterial Agents ; Bacterial Toxins
Language	English
Publishing date	2023-02-13
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2619676-1
ISSN	2235-2988 ; 2235-2988
ISSN (online)	2235-2988
ISSN	2235-2988
DOI	10.3389/fcimb.2023.1127786
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Whole-Exome Sequencing Reveals Mutational Signature of Hypertrophic Cardiomyopathy.

Wang, Xi-Qin / Yuan, Fang / Yu, Bao-Rui

International journal of general medicine

2023 Volume 16, Page(s) 4617–4628

Abstract: Background: Hypertrophic cardiomyopathy (HCM) is an extremely insidious and lethal disease caused by genetic variation. It has been studied for nearly 70 years since its discovery, but its cause of the disease remains a mystery. This study is aimed to ... ...

Abstract	Background: Hypertrophic cardiomyopathy (HCM) is an extremely insidious and lethal disease caused by genetic variation. It has been studied for nearly 70 years since its discovery, but its cause of the disease remains a mystery. This study is aimed to explore the genetic pathogenesis of HCM in order to provide new insight for the diagnosis and treatment of HCM. Methods: Patients with HCM at 4 hospitals from January 1, 2020, to December 31, 2021, were collected. Peripheral blood of these patients was collected for whole exome sequencing. Moreover, data on the HCM transcriptome were analyzed in the GEO database. Results: Totally, 14 patients were enrolled, and 6 single-nucleotide variation (SNV) mutant genes represented by MUC12 were observed. Most of the gene mutations in HCM patients were synonymous and non-synonymous, and the types of base mutations were mainly C > T and G > A. Copy number variants (CNVs) predominantly occurred on chromosome 1 in HCM patients. Furthermore, we found that the only ATP2A2 gene was differentially expressed in 3 groups of transcriptome data in GEO database, and the presence of ATP2A2 mutation in 10 samples was observed in this study. Conclusion: In summary, 7 mutated genes represented by MUC12 and ATP2A2 were found in this study, which may provide novel insights into the pathogenic mechanism of HCM.
Language	English
Publishing date	2023-10-11
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	2452220-X
ISSN	1178-7074
ISSN	1178-7074
DOI	10.2147/IJGM.S422598
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Article ; Online: The impacts of human migration and city lockdowns on specific air pollutants during the COVID-19 outbreak: A spatial perspective

Zeng, Jingjing / Bao, Rui

Journal of Environmental Management. 2021 Mar., v. 282 p.111907-

2021

Abstract: The outbreak of COVID-19 continues to bring unprecedented shock to mankind's socioeconomic activities, and to the wider environment. China, as the early epicenter of the pandemic, locked down one-third of its cities in an attempt to prevent the rapid ... ...

Abstract	The outbreak of COVID-19 continues to bring unprecedented shock to mankind's socioeconomic activities, and to the wider environment. China, as the early epicenter of the pandemic, locked down one-third of its cities in an attempt to prevent the rapid spread of the virus. Human migration patterns have subsequently been radically altered and many regions have seen perceived improvements in air quality during the lockdowns. This study empirically examines the relationship between human migration and air pollution and further evaluates the causal impacts of the lockdowns. A spatial econometric method and a spatial explicit counterfactual framework are employed in this study. The key findings are as follows: i) a considerable amount of variation in AQI, PM₁₀, PM₂.₅, and NO₂ concentration can be explained by human migration but we fail to find suggestive evidence in the cases of SO₂ and CO; ii) the implementation of lockdown measures led to a significant reduction in AQI (18.1%), PM₂.₅ (22.2%), NO₂ (20.5%), and PM₁₀ (10.7%), but has no meaningful impacts on SO₂, CO and O₃ levels; iii) further analysis indicates that the impacts of lockdown policies varied by control stringency and by regional heterogeneity. Our findings are of great importance for the Chinese government to create a stronger and more coherent framework in its efforts to tackle air pollution.
Keywords	COVID-19 infection ; air ; air pollution ; air quality ; econometrics ; environmental management ; humans ; immigration ; pandemic ; viruses ; China ; COVID-19 ; Human migration ; City lockdowns ; Spatial effects ; Heterogeneity
Language	English
Dates of publication	2021-03
Publishing place	Elsevier Ltd
Document type	Article ; Online
ZDB-ID	184882-3
ISSN	1095-8630 ; 0301-4797
ISSN (online)	1095-8630
ISSN	0301-4797
DOI	10.1016/j.jenvman.2020.111907
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Pseudomonas aeruginosa two-component system CprRS regulates HigBA expression and bacterial cytotoxicity in response to LL-37 stress.

Song, Yingjie / Zhang, Siping / Zhao, Ninglin / Nong, Cheng / He, Yongxing / Bao, Rui

PLoS pathogens

2024 Volume 20, Issue 1, Page(s) e1011946

Abstract: Pseudomonas aeruginosa is a highly pathogenic bacterium known for its ability to sense and coordinate the production of virulence factors in response to host immune responses. However, the regulatory mechanisms underlying this process have remained ... ...

Abstract	Pseudomonas aeruginosa is a highly pathogenic bacterium known for its ability to sense and coordinate the production of virulence factors in response to host immune responses. However, the regulatory mechanisms underlying this process have remained largely elusive. In this study, we investigate the two-component system CprRS in P. aeruginosa and unveil the crucial role of the sensor protein CprS in sensing the human host defense peptide LL-37, thereby modulating bacterial virulence. We demonstrate that CprS acts as a phosphatase in the presence of LL-37, leading to the phosphorylation and activation of the response regulator CprR. The results prove that CprR directly recognizes a specific sequence within the promoter region of the HigBA toxin-antitoxin system, resulting in enhanced expression of the toxin HigB. Importantly, LL-37-induced HigB expression promotes the production of type III secretion system effectors, leading to reduced expression of proinflammatory cytokines and increased cytotoxicity towards macrophages. Moreover, mutations in cprS or cprR significantly impair bacterial survival in both macrophage and insect infection models. This study uncovers the regulatory mechanism of the CprRS system, enabling P. aeruginosa to detect and respond to human innate immune responses while maintaining a balanced virulence gene expression profile. Additionally, this study provides new evidence and insights into the complex regulatory system of T3SS in P. aeruginosa within the host environment, contributing to a better understanding of host-microbe communication and the development of novel strategies to combat bacterial infections.
MeSH term(s)	Humans ; Pseudomonas aeruginosa/metabolism ; Pseudomonas Infections/genetics ; Pseudomonas Infections/microbiology ; Virulence Factors/genetics ; Virulence Factors/metabolism ; Virulence ; Type III Secretion Systems/metabolism ; Bacterial Proteins/metabolism ; Gene Expression Regulation, Bacterial
Chemical Substances	Virulence Factors ; Type III Secretion Systems ; Bacterial Proteins
Language	English
Publishing date	2024-01-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	2205412-1
ISSN	1553-7374 ; 1553-7374
ISSN (online)	1553-7374
ISSN	1553-7374
DOI	10.1371/journal.ppat.1011946
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Article ; Online: Molecular mechanism of siderophore regulation by the Pseudomonas aeruginosa BfmRS two-component system in response to osmotic stress.

Song, Yingjie / Wu, Xiyu / Li, Ze / Ma, Qin Qin / Bao, Rui

Communications biology

2024 Volume 7, Issue 1, Page(s) 295

Abstract: Pseudomonas aeruginosa, a common nosocomial pathogen, relies on siderophores to acquire iron, crucial for its survival in various environments and during host infections. However, understanding the molecular mechanisms of siderophore regulation remains ... ...

Abstract	Pseudomonas aeruginosa, a common nosocomial pathogen, relies on siderophores to acquire iron, crucial for its survival in various environments and during host infections. However, understanding the molecular mechanisms of siderophore regulation remains incomplete. In this study, we found that the BfmRS two-component system, previously associated with biofilm formation and quorum sensing, is essential for siderophore regulation under high osmolality stress. Activated BfmR directly bound to the promoter regions of pvd, fpv, and femARI gene clusters, thereby activating their transcription and promoting siderophore production. Subsequent proteomic and phenotypic analyses confirmed that deletion of BfmRS reduces siderophore-related proteins and impairs bacterial survival in iron-deficient conditions. Furthermore, phylogenetic analysis demonstrated the high conservation of the BfmRS system across Pseudomonas species, functional evidences also indicated that BfmR homologues from Pseudomonas putida KT2440 and Pseudomonas sp. MRSN12121 could bind to the promoter regions of key siderophore genes and osmolality-mediated increases in siderophore production were observed. This work illuminates a novel signaling pathway for siderophore regulation and enhances our understanding of siderophore-mediated bacterial interactions and community establishment.
MeSH term(s)	Humans ; Siderophores/metabolism ; Pseudomonas aeruginosa/genetics ; Pseudomonas aeruginosa/metabolism ; Osmotic Pressure ; Phylogeny ; Proteomics ; Iron/metabolism ; Pseudomonas/metabolism ; Pseudomonas Infections
Chemical Substances	Siderophores ; Iron (E1UOL152H7)
Language	English
Publishing date	2024-03-09
Publishing country	England
Document type	Journal Article
ISSN	2399-3642
ISSN (online)	2399-3642
DOI	10.1038/s42003-024-05995-z
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