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Article ; Online: Cost-effectiveness evaluation of the PROPPR trial transfusion protocols.

Callcut, Rachael A / Simpson, Kit N / Baraniuk, Sarah / Fox, Erin E / Tilley, Barbara C / Holcomb, John B

2020 Volume 60, Issue 5, Page(s) 922–931

Abstract: Background: There have been no prior investigations of the cost effectiveness of transfusion strategies for trauma resuscitation. The Pragmatic, Randomized, Optimal Platelet and Plasma Ratios (PROPPR) study was a Phase III multisite, randomized trial in ...

Abstract	Background: There have been no prior investigations of the cost effectiveness of transfusion strategies for trauma resuscitation. The Pragmatic, Randomized, Optimal Platelet and Plasma Ratios (PROPPR) study was a Phase III multisite, randomized trial in 680 subjects comparing the efficacy of 1:1:1 transfusion ratios of plasma and platelets to red blood cells with the 1:1:2 ratio. We hypothesized that 1:1:1 transfusion results in an acceptable incremental cost-effectiveness ratio, when estimated using patients' age-specific life expectancy and cost of care during the 30-day PROPPR trial period. Study design and methods: International Classification of Diseases, Ninth Revision codes were prospectively collected, and subjects were matched 1:2 to subjects in the Healthcare Utilization Program State Inpatient Data to estimate cost weights. We used a decision tree analysis, combined with standard costs and estimated years of expected survival to determine the cost effectiveness of the two treatments. Results: The 1:1:1 group had higher overall costs for the blood products but were more likely to achieve hemostasis and decreased hemorrhagic death by 24 hours (p = 0.006). For every 100 patients treated in the 1:1:1 group, eight more achieved hemostasis than in the 1:1:2 group. At 30 days, the total hospital cost per 100 patients was $5.6 million in the 1:1:1 group compared with $5.0 million in the 1:1:2 group. For each 100 patients, the 1:1:1 group had 218.5 more years of life expectancy. This was at a cost of $2994 per year gained. Conclusion: The 1:1:1 transfusion ratio in severely injured hemorrhaging trauma patients is a very cost-effective strategy for increasing hemostasis and decreasing trauma deaths.
MeSH term(s)	Adolescent ; Adult ; Blood Cell Count/economics ; Blood Platelets/cytology ; Blood Transfusion/economics ; Blood Transfusion/methods ; Blood Transfusion/mortality ; Blood Transfusion/statistics & numerical data ; Cost-Benefit Analysis ; Erythrocyte Count ; Erythrocyte Transfusion/economics ; Erythrocyte Transfusion/methods ; Erythrocyte Transfusion/mortality ; Erythrocyte Transfusion/statistics & numerical data ; Erythrocytes/cytology ; Female ; Hemorrhage/blood ; Hemorrhage/mortality ; Hemorrhage/therapy ; Hospital Mortality ; Humans ; Length of Stay/economics ; Length of Stay/statistics & numerical data ; Male ; Middle Aged ; Plasma/cytology ; Platelet Transfusion/economics ; Platelet Transfusion/methods ; Platelet Transfusion/mortality ; Platelet Transfusion/statistics & numerical data ; Resuscitation/mortality ; Resuscitation/statistics & numerical data ; Young Adult
Language	English
Publishing date	2020-05-01
Publishing country	United States
Document type	Clinical Trial, Phase III ; Journal Article ; Multicenter Study ; Pragmatic Clinical Trial ; Randomized Controlled Trial ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	208417-x
ISSN	1537-2995 ; 0041-1132
ISSN (online)	1537-2995
ISSN	0041-1132
DOI	10.1111/trf.15784
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Zs.A 284: Show issues

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Article ; Online: Factors associated with self-reported anal cancer screening history in men who have sex with men.

Hicks, Joseph T / Hwang, Lu-Yu / Baraniuk, Sarah / White, Margaret / Chiao, Elizabeth Y / Onwuka, Nkechi / Ross, Michael W / Nyitray, Alan G

Sexual health

2018 Volume 16, Issue 1, Page(s) 96–98

Abstract: Background Men who have sex with men (MSM) are at greater risk of developing anal cancer caused by human papillomavirus (HPV) than the rest of the general population. Currently, there are no formal national guidelines in the US advising men how and when ... ...

Abstract	Background Men who have sex with men (MSM) are at greater risk of developing anal cancer caused by human papillomavirus (HPV) than the rest of the general population. Currently, there are no formal national guidelines in the US advising men how and when to get anal cancer screening. We sought to assess differences in demographics, familiarity and anxiety about anal cancer among men who report having had anal cancer screening (i.e. anal cytology and/or a digital anorectal examination (DARE)). Methods: MSM were recruited to participate in a study to assess the feasibility of teaching self and partner anal examinations as a means of screening for anal cancer. Data for this secondary analysis were obtained using a written pre-test and a computer-assisted self-interview. Factors associated with screening were assessed with multivariable logistic regression to allow calculation of adjusted odds ratios (aORs). Results: Of the 197 participants with data, 145 (73.6%) reported having had anal cancer screening (either anal cytology, DARE or both) during their lifetime. Men who were younger, Black and HIV-negative were associated with decreased odds of reporting any type of anal cancer screening. For example, compared with White men, Black men were 80% less likely to report screening (aOR 0.2; 95% confidence interval (CI) 0.1-0.5). Self-perception of anal cancer knowledge was not associated with screening in multivariable analysis (aOR 1.6; 95% CI 0.6-3.9). Conclusions: Age, race and HIV status were independently associated with a history of anal cancer screening.
MeSH term(s)	Adult ; Age Factors ; Aged ; Aged, 80 and over ; Anus Neoplasms/prevention & control ; Early Detection of Cancer/statistics & numerical data ; Homosexuality, Male ; Humans ; Male ; Middle Aged ; Race Factors ; Risk Factors ; Self Report
Language	English
Publishing date	2018-12-03
Publishing country	Australia
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	2256731-8
ISSN	1449-8987 ; 1448-5028
ISSN (online)	1449-8987
ISSN	1448-5028
DOI	10.1071/SH18039
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Zs.A 6421: Show issues

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Article: Dependence, hyper-dependence and hypothesis testing in clinical trials.

Moyé, Lemuel A / Baraniuk, Sarah

Contemporary clinical trials

2007 Volume 28, Issue 1, Page(s) 68–78

Abstract: While investigators designing clinical trials face the important issue of endpoint selection, an equally troublesome concern can be the a priori selection of the endpoint analysis. In this latter circumstance, there may be only one endpoint of interest ... ...

Abstract	While investigators designing clinical trials face the important issue of endpoint selection, an equally troublesome concern can be the a priori selection of the endpoint analysis. In this latter circumstance, there may be only one endpoint of interest in the clinical trial, but several competing endpoint analyses are available (e.g., an analysis of the endpoint that is adjusted for clinical center versus an analysis that is adjusted for geographic region versus an unadjusted analysis). An example that demonstrates the unsatisfactory conclusions that ambiguous choices can produce is offered. A procedure utilizing conditional probability is provided that permits the conservation of type I error when the investigators have one endpoint and several worthy competitor endpoint analyses that are each prospectively identified and carried out at the trial's conclusion. When the high levels of dependence among these analyses are taken into account, it is possible to carry out the hypothesis tests in a way that 1) provides practicable type I error levels for each analysis, and 2) conserves the familywise type I error. In circumstances in which the endpoint and all members of the family of analyses are selected during the design phase of the trial, this procedure provides confirmatory conclusions as opposed to exploratory findings.
MeSH term(s)	Clinical Trials as Topic/methods ; Clinical Trials as Topic/standards ; Humans ; Research Design ; Statistics as Topic/methods
Language	English
Publishing date	2007-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	2182176-8
ISSN	1559-2030 ; 1551-7144
ISSN (online)	1559-2030
ISSN	1551-7144
DOI	10.1016/j.cct.2006.05.010
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Zs.A 1581: Show issues

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Article ; Online: Comparison of the global statistical test and composite outcome for secondary analyses of multiple coronary heart disease outcomes.

Baraniuk, Sarah / Seay, Roann / Sinha, Arup K / Piller, Linda B

Progress in cardiovascular diseases

2012 Volume 54, Issue 4, Page(s) 357–361

Abstract: Multiple outcomes (or multiple endpoints), such as mortality and recurrent myocardial infarction, are increasingly common in clinical trials and are often of interest in secondary analyses. Traditionally, a clinical trial protocol is built around a ... ...

Abstract	Multiple outcomes (or multiple endpoints), such as mortality and recurrent myocardial infarction, are increasingly common in clinical trials and are often of interest in secondary analyses. Traditionally, a clinical trial protocol is built around a single event as its primary outcome, with several secondary outcomes specified, the analyses for which lack the same level of power. To accommodate all the relevant outcomes and to increase the power of the comparison in trials evaluating the efficacy of treatments for coronary heart disease, investigators often chose to construct a composite outcome. The more conventional composite outcome fails to account for the relative importance and the relationship (correlation) among its components. The purpose of this work is to demonstrate the usefulness of the Global Statistical Test, which considers the correlation between multiple outcomes, as an alternative strategy for these situations and to demonstrate its effect on hypothesis testing and power analysis issues in comparison with the traditional composite outcome analysis. Data from the cardiovascular clinical trial Systolic Hypertension in the Elderly Population are used as an example.
MeSH term(s)	Coronary Disease/complications ; Coronary Disease/mortality ; Coronary Disease/therapy ; Data Interpretation, Statistical ; Humans ; Logistic Models ; Models, Statistical ; Outcome Assessment (Health Care) ; Randomized Controlled Trials as Topic/statistics & numerical data ; Statistics as Topic ; Treatment Outcome
Language	English
Publishing date	2012-01
Publishing country	United States
Document type	Comparative Study ; Journal Article
ZDB-ID	209312-1
ISSN	1873-1740 ; 1532-8643 ; 0033-0620
ISSN (online)	1873-1740 ; 1532-8643
ISSN	0033-0620
DOI	10.1016/j.pcad.2011.11.001
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Zs.A 229: Show issues

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Article: Organizational factors related to safety in a psychiatric hospital: employee perceptions.

Calabro, Karen / Baraniuk, Sarah

AAOHN journal : official journal of the American Association of Occupational Health Nurses

2003 Volume 51, Issue 10, Page(s) 425–432

Abstract: Physical assaults on mental health care workers by aggressive patients were the leading cause of occupational injuries to staff working in a community psychiatric hospital. More than dollar 1 million was estimated to be lost in 1 year because of these ... ...

Abstract	Physical assaults on mental health care workers by aggressive patients were the leading cause of occupational injuries to staff working in a community psychiatric hospital. More than dollar 1 million was estimated to be lost in 1 year because of these occupational injuries. This problem was assessed by examining the organizational factors related to safety at the hospital. The cross sectional survey design measured the perceptions of mental health care workers about the commitment of management to safety (i.e., safety climate). Overall, results indicated the subscale for safety climate was high (3.77 +/- .66 [mean +/- SD] on a 5 scale), given the magnitude of recalled incidents and injuries involving patients against staff. Safety climate was associated with three variables that included administrative controls, occupational stress, and job task demands. Results of the study were useful in determining specific changes for improving safety. The study findings demonstrated the practicality and feasibility of in-house assessments to diagnose areas that require attention, support, and improvement.
MeSH term(s)	Adult ; Attitude of Health Personnel ; Data Collection/methods ; Female ; Hospitals, Psychiatric/organization & administration ; Hospitals, Psychiatric/standards ; Humans ; Male ; Middle Aged ; Occupational Health ; Personnel, Hospital/psychology ; Safety Management/organization & administration ; Safety Management/standards ; Violence/prevention & control ; Workplace/organization & administration ; Workplace/psychology ; Wounds and Injuries/prevention & control
Language	English
Publishing date	2003-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	632757-6
ISSN	0891-0162
ISSN	0891-0162
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Zs.B 624: Show issues

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Article ; Online: Assessing protocol adherence in a clinical trial with ordered treatment regimens: Quantifying the pragmatic, randomized optimal platelet and plasma ratios (PROPPR) trial experience.

Zhu, Hongjian / Fox, Erin E / Baraniuk, Sarah / Holcomb, John B / Wade, Charles E / Del Junco, Deborah J / Tilley, Barbara C

Injury

2016 Volume 47, Issue 10, Page(s) 2131–2137

Abstract: Background: Medication dispensing errors are common in clinical trials, and have a significant impact on the quality and validity of a trial. Therefore, the definition, calculation and evaluation of such errors are important for supporting a trial's ... ...

Abstract	Background: Medication dispensing errors are common in clinical trials, and have a significant impact on the quality and validity of a trial. Therefore, the definition, calculation and evaluation of such errors are important for supporting a trial's conclusions. A variety of medication dispensing errors can occur. In this paper, we focus on errors in trials where the intervention includes multiple therapies that must be given in a pre-specified order that varies across treatment arms and varies in duration. Methods: The Pragmatic, Randomized Optimal Platelet and Plasma Ratios (PROPPR) trial was a Phase III multi-site, randomized trial to compare the effectiveness and safety of 1:1:1 transfusion ratios of plasma and platelets to red blood cells with a 1:1:2 ratio. In this trial, these three types of blood products were to be transfused in a pre-defined order that differed by treatment arm. In this paper, we present approaches from the PROPPR trial that we used to define and calculate the occurrence of out of order blood transfusion errors. We applied the proposed method to calculate protocol adherence to the specified order of transfusion in each treatment arm. Results: Using our proposed method, protocol adherence was greater in the 1:1:1 group than in the 1:1:2 group (96% vs 93%) (p<0.0001), although out of order transfusion errors in both groups were low. Final transfusion ratios of plasma to platelets to red blood cells for the 1:1:1 ratio group was 0.93:1.32:1, while the transfusion ratio for the 1:1:2 ratio group was 0.48:0.48:1. Conclusions: Overall, PROPPR adherence to blood transfusion order pre-specified in the protocol was high, and the required order of transfusions for the 1:1:2 group was more difficult to achieve. The approaches proposed in this manuscript were useful in evaluating the PROPPR adherence and are potentially useful for other trials where a specific treatment orders with varying durations must be maintained.
MeSH term(s)	Blood Component Transfusion/adverse effects ; Blood Component Transfusion/methods ; Blood Platelets/cytology ; Clinical Protocols ; Erythrocyte Count ; Guideline Adherence ; Humans ; Plasma/cytology
Language	English
Publishing date	2016-07-21
Publishing country	Netherlands
Document type	Clinical Trial, Phase III ; Journal Article ; Multicenter Study ; Pragmatic Clinical Trial ; Randomized Controlled Trial
ZDB-ID	218778-4
ISSN	1879-0267 ; 0020-1383
ISSN (online)	1879-0267
ISSN	0020-1383
DOI	10.1016/j.injury.2016.07.028
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Zs.A 778: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Implementing a mobile stroke unit program in the United States: why, how, and how much?

Rajan, Suja S / Rajan, Suja / Baraniuk, Sarah / Parker, Stephanie / Wu, Tzu-Ching / Bowry, Ritvij / Grotta, James C

JAMA neurology

2015 Volume 72, Issue 2, Page(s) 229–234

Abstract: Importance: There are many ways a mobile stroke unit (MSU) might prove valuable for patients with ischemic and hemorrhagic stroke, such as earlier recognition, more accurate triage, improved management of blood pressure and other critical physiological ... ...

Abstract	Importance: There are many ways a mobile stroke unit (MSU) might prove valuable for patients with ischemic and hemorrhagic stroke, such as earlier recognition, more accurate triage, improved management of blood pressure and other critical physiological variables, and eventually earlier implementation of effective therapies. The MSU may be particularly valuable for treatment of patients with acute ischemic stroke with tissue plasminogen activator (tPA) within 4.5 hours of symptom onset, the most evidence-based effective emergency treatment for the most prevalent stroke diagnosis. Objectives: To review existing data on prehospital stroke treatment, especially relevant to MSU technology, to identify gaps in our understanding of MSU feasibility, especially relevant to applying the MSU strategy in the United States, and to describe the Houston MSU program and clinical trial. Evidence review: Published data from English-language journals in PubMed from 1995 to present reviewing early treatment with tPA and prehospital stroke evaluation and treatment. Findings: The MSU may result in an overall shift toward earlier evaluation and treatment with tPA, particularly into the first hour after symptom onset, leading to substantially better outcomes. As a result of improved clinical outcomes owing to earlier treatment, the costs of an MSU program may be offset by a reduction in the costs of long-term stroke care and an increase in quality-adjusted life-years, thereby supporting more widespread use of this technology. To make MSU deployment more practical, the vascular neurologist aboard the MSU must be replaced by a remote vascular neurologist connected to the MSU by telemedicine, reducing manpower requirements and costs. Conclusions and relevance: The MSU strategy could dramatically transform the way acute stroke is managed in the United States. A prospective study evaluating the logistics, outcomes, and cost-effectiveness of this approach is needed and under way.
MeSH term(s)	Clinical Trials as Topic ; Early Medical Intervention/economics ; Early Medical Intervention/organization & administration ; Early Medical Intervention/standards ; Humans ; Mobile Health Units/economics ; Mobile Health Units/organization & administration ; Mobile Health Units/standards ; Program Development/economics ; Program Development/methods ; Program Development/standards ; Stroke/therapy ; United States
Keywords	covid19
Language	English
Publishing date	2015-02
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2702023-X
ISSN	2168-6157 ; 2168-6149
ISSN (online)	2168-6157
ISSN	2168-6149
DOI	10.1001/jamaneurol.2014.3618
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Ui II Zs.191: Show issues

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Article ; Online: Cancer perceptions: implications from the 2007 Health Information National Trends Survey.

Kowalkowski, Marc A / Hart, Stacey L / Du, Xianglin L / Baraniuk, Sarah / Latini, David M

Journal of cancer survivorship : research and practice

2012 Volume 6, Issue 3, Page(s) 287–295

Abstract: Introduction: Research has demonstrated associations between sociodemographic characteristics and illness perceptions; however, the impact of cancer exposure through personal or family diagnoses is not well-studied. The purposes of this study were to ... ...

Abstract	Introduction: Research has demonstrated associations between sociodemographic characteristics and illness perceptions; however, the impact of cancer exposure through personal or family diagnoses is not well-studied. The purposes of this study were to examine different cancer beliefs and disparities in cancer beliefs across groups of individuals with distinct cancer histories and to identify whether cancer history predicts a set of cancer beliefs. Methods: Using Leventhal's Common Sense Model and data from the 2007 Health Information National Trends Survey (N = 7,172), we constructed multivariable logistic regression models to evaluate the effect of different stimuli, including cancer experience on cancer perceptions (e.g., prevention, causation, outcome, worry). Results: Findings indicated significant associations between cancer history and cancer perceptions. Individuals with family and personal cancer histories were more likely than individuals without any cancer history to worry about getting cancer (OR = 3.55, 95 %CI = 2.53-4.99), agree they will develop cancer in the future (OR = 8.81, 95 %CI = 6.12-12.67) and disagree that cancer is most often caused by a person's behavior or lifestyle (OR = 1.24, 95 %CI = 1.01-1.52). Conclusions: Cancer history affects perceptions throughout the cancer continuum. Additionally, cancer history may influence coping behaviors and outcomes. Cancer education and survivorship programs should assess important variables such as cancer history to more effectively tailor services and monitor evolving needs throughout cancer care. Implications for cancer survivors: Integrating cancer history information into patient education programs tailored to an individual's needs may better empower survivors and their family members to effectively promote informed decision-making about screening and preventive health behaviors, manage cancer worry, and enhance quality of life.
MeSH term(s)	Adaptation, Psychological ; Attitude to Health ; Culture ; Family ; Female ; Genetic Predisposition to Disease/psychology ; Health Behavior ; Health Knowledge, Attitudes, Practice ; Health Surveys ; Humans ; Male ; Middle Aged ; Neoplasms/diagnosis ; Neoplasms/prevention & control ; Neoplasms/psychology ; Perception
Language	English
Publishing date	2012-03-29
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2388888-X
ISSN	1932-2267 ; 1932-2259
ISSN (online)	1932-2267
ISSN	1932-2259
DOI	10.1007/s11764-012-0217-y
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Article ; Online: Risk factors for spinal surgical site infection, Houston, Texas.

Boston, Kelley M / Baraniuk, Sarah / O'Heron, Shana / Murray, Kristy O

Infection control and hospital epidemiology

2009 Volume 30, Issue 9, Page(s) 884–889

Abstract: Objective: Because of an increase in the rate of surgical site infections (SSIs) following spinal procedures at the study hospital, we conducted a study to determine risk factors associated with the development of a SSI.: Design: Case-control study.!# ...

Abstract	Objective: Because of an increase in the rate of surgical site infections (SSIs) following spinal procedures at the study hospital, we conducted a study to determine risk factors associated with the development of a SSI. Design: Case-control study. Setting: A community hospital in Houston, Texas, with more than 500 beds. Patients: Fifty-five case patients who developed SSI after spinal surgery and 179 control patients who did not develop SSI after spinal surgery. Methods: We examined patient- and hospital-associated risk factors for SSI by using existing data on patients who underwent spinal operations at the study hospital between December 2003 and August 2005. Multivariable analysis was conducted using logistic regression to determine significant risk factors associated with SSI. Results: The presence of comorbidities (odds ratio [OR], 3.15 [95% confidence interval (CI), 1.20-8.26]) and surgical duration greater than the population median of 100 minutes (OR, 2.48 [95% CI, 1.12-5.49]) were identified as independent risk factors for SSI. The use of only povidone-iodine for preoperative skin antisepsis was found to be protective (OR, 0.16 [95% CI, 0.06-0.45]). Specific operating room, hospital staff involved in the procedures, workers' compensation status, method of hair removal, smoking status, or incontinence were not statistically significant. Conclusions: The presence of comorbidities and increased surgical duration are risks for postoperative infection. The use of only povidone-iodine was found to decrease the risk of infection.
MeSH term(s)	Adult ; Aged ; Case-Control Studies ; Female ; Hospitals, Community ; Humans ; Iodine/administration & dosage ; Male ; Middle Aged ; Povidone/administration & dosage ; Risk Factors ; Spine/surgery ; Surgical Wound Infection/epidemiology ; Surgical Wound Infection/etiology ; Surgical Wound Infection/prevention & control ; Texas/epidemiology ; Young Adult
Chemical Substances	Iodine (9679TC07X4) ; Povidone (FZ989GH94E)
Language	English
Publishing date	2009-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	639378-0
ISSN	1559-6834 ; 0195-9417 ; 0899-823X
ISSN (online)	1559-6834
ISSN	0195-9417 ; 0899-823X
DOI	10.1086/605323
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Article ; Online: A qualitative investigation among men who have sex with men on the acceptability of performing a self- or partner anal exam to screen for anal cancer.

Butame, Seyram A / Lawler, Sylvia / Hicks, Joseph T / Wilkerson, J Michael / Hwang, Lu-Yu / Baraniuk, Sarah / Ross, Michael W / Chiao, Elizabeth Yu / Nyitray, Alan G

Cancer causes & control : CCC

2017 Volume 28, Issue 10, Page(s) 1157–1166

Abstract: Purpose: Persistent infection with oncogenic human papillomavirus (HPV) is the primary cause of anal cancer, a disease that disproportionately affects men who have sex with men (MSM); however, there is no uniform screening protocol to detect anal cancer. ...

Abstract	Purpose: Persistent infection with oncogenic human papillomavirus (HPV) is the primary cause of anal cancer, a disease that disproportionately affects men who have sex with men (MSM); however, there is no uniform screening protocol to detect anal cancer. This qualitative study explores whether a self-anal exam (SAE) or partner anal exam (PAE), that includes self-palpation or palpation of a partner's anal canal, is an acceptable and self-efficacious screening test, which will cue appropriate follow-up care in MSM. Methods: Twenty-four MSM living in Houston took part in four focus group sessions eliciting their responses to a study teaching them to perform an SAE or PAE (SAE/PAE). Participants were asked about the acceptability and feasibility of executing an SAE/PAE routinely. Thematic analysis of session transcripts was used to identify common patterns in participant responses. Results: Overall, participants expressed self-efficacy for performing an SAE/PAE and voiced a preference for being taught the procedure by a clinician. Participants agreed that they would consult with a clinician if they ever discovered an abnormality while performing an SAE/PAE. A lack of knowledge about anal cancer among MSM may present a barrier to adopting SAE/PAE. In discussing their experience of the exams, some participants suggested that it could become a routine practice for them. Conclusions: Our findings suggest that SAE and PAE, as a screen for anal cancer, are acceptable and feasible to MSM. Future research should explore attitudes and beliefs of MSM, with the aim of improving anal cancer education and understanding of pathologic findings.
MeSH term(s)	Adult ; Aged ; Anus Neoplasms/diagnosis ; Early Detection of Cancer/psychology ; Homosexuality, Male/psychology ; Humans ; Male ; Middle Aged ; Qualitative Research ; Self Efficacy
Language	English
Publishing date	2017-08-04
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1064022-8
ISSN	1573-7225 ; 0957-5243
ISSN (online)	1573-7225
ISSN	0957-5243
DOI	10.1007/s10552-017-0935-6
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Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito