Article ; Online: Copper(II) complexes with meclofenamate ligands: Structure, interaction with DNA and albumins, antioxidant and anticholinergic activity.
Journal of inorganic biochemistry
2021 Volume 217, Page(s) 111357
Abstract: The interaction of copper(II) with the non-steroidal anti-inflammatory drug sodium meclofenamate (Na-mclf) in the presence or absence of the nitrogen-donor co-ligands pyridine (py) or 2,2'-bipyridylamine (bipyam), yielded the novel Cu(II) complexes [ ... ...
| Abstract | The interaction of copper(II) with the non-steroidal anti-inflammatory drug sodium meclofenamate (Na-mclf) in the presence or absence of the nitrogen-donor co-ligands pyridine (py) or 2,2'-bipyridylamine (bipyam), yielded the novel Cu(II) complexes [Cu |
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| MeSH term(s) | Acetylcholinesterase/metabolism ; Animals ; Butyrylcholinesterase/metabolism ; Cattle ; Cholinesterase Inhibitors/chemical synthesis ; Cholinesterase Inhibitors/chemistry ; Cholinesterase Inhibitors/metabolism ; Coordination Complexes/chemical synthesis ; Coordination Complexes/chemistry ; Coordination Complexes/metabolism ; Copper/chemistry ; DNA/metabolism ; Free Radical Scavengers/chemical synthesis ; Free Radical Scavengers/chemistry ; Free Radical Scavengers/metabolism ; Intercalating Agents/chemical synthesis ; Intercalating Agents/chemistry ; Intercalating Agents/metabolism ; Ligands ; Meclofenamic Acid/analogs & derivatives ; Meclofenamic Acid/metabolism ; Protein Binding ; Serum Albumin, Bovine/metabolism |
| Chemical Substances | Cholinesterase Inhibitors ; Coordination Complexes ; Free Radical Scavengers ; Intercalating Agents ; Ligands ; Serum Albumin, Bovine (27432CM55Q) ; Meclofenamic Acid (48I5LU4ZWD) ; Copper (789U1901C5) ; DNA (9007-49-2) ; calf thymus DNA (91080-16-9) ; Acetylcholinesterase (EC 3.1.1.7) ; Butyrylcholinesterase (EC 3.1.1.8) |
| Language | English |
| Publishing date | 2021-01-24 |
| Publishing country | United States |
| Document type | Journal Article |
| ZDB-ID | 162843-4 |
| ISSN | 1873-3344 ; 0162-0134 |
| ISSN (online) | 1873-3344 |
| ISSN | 0162-0134 |
| DOI | 10.1016/j.jinorgbio.2021.111357 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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