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  1. Book ; Thesis: Effekte der tiefen Hirnstimulation des ncl. Subthalamicus auf die Gangmotorik bei Morbus Parkinson

    Barnaure, Isabelle

    2011  

    Author's details von Isabelle Barnaure
    Language German
    Size 67 S., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Kiel, Univ., Diss., 2011
    HBZ-ID HT017164490
    Database Catalogue ZB MED Medicine, Health

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    2012 D 204 order for loan Magazin

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  2. Article ; Online: Magnetic resonance imaging in the evaluation of cervical foraminal stenosis: comparison of 3D T2 SPACE with sagittal oblique 2D T2 TSE.

    Barnaure, I / Galley, J / Fritz, B / Sutter, R

    Skeletal radiology

    2022  Volume 51, Issue 7, Page(s) 1453–1462

    Abstract: Objective: The oblique orientation of the cervical neural foramina challenges the implementation of a short MRI protocol with concurrent excellent visualization of the spine. While sagittal oblique T2-weighted sequences permit good evaluation of the ... ...

    Abstract Objective: The oblique orientation of the cervical neural foramina challenges the implementation of a short MRI protocol with concurrent excellent visualization of the spine. While sagittal oblique T2-weighted sequences permit good evaluation of the cervical neuroforamina, all segments may not be equally well depicted on a single sequence and conspicuity of foraminal stenosis may be limited. 3D T2-weighted sequences can be reformatted in arbitrary planes, including the sagittal oblique. We set out to compare 3D T2w SPACE sequences with sagittal oblique reformations and sagittal oblique 2D T2w TSE sequences for the evaluation of cervical foraminal visibility and stenosis.
    Materials and methods: Sixty consecutive patients who underwent MRI of the cervical spine with sagittal oblique 2D T2w TSE and 3D T2w SPACE sequences were included. Image homogeneity of the sequences was evaluated. Imaging sets were assessed for structure visibility and foraminal stenosis by two independent readers. Results of the sequences were compared by Wilcoxon matched-pairs tests. Interreader agreement was evaluated by weighted κ.
    Results: Visibility of most structures was rated good to excellent on both sequences (mean visibility scores ≥ 4.5 of 5), though neuroforaminal contents were better seen on sagittal oblique T2w TSE (mean scores 4.1-4.6 vs. 3.1-4.1 on 3D T2w SPACE, p < 0.01). Stenosis grades were comparable between sequences (mean 1.1-2.6 of 4), with slightly higher values for 3D T2w SPACE at some levels (difference ≤ 0.3 points).
    Conclusion: 3D T2w SPACE is comparable with sagittal oblique 2D T2w TSE in the evaluation of cervical neural foramina.
    MeSH term(s) Cervical Vertebrae/diagnostic imaging ; Cervical Vertebrae/pathology ; Constriction, Pathologic/pathology ; Humans ; Imaging, Three-Dimensional/methods ; Magnetic Resonance Imaging/methods ; Neck
    Language English
    Publishing date 2022-01-10
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 527592-1
    ISSN 1432-2161 ; 0364-2348
    ISSN (online) 1432-2161
    ISSN 0364-2348
    DOI 10.1007/s00256-022-03988-9
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  3. Article ; Online: Supra-aortic Vessel Catheterization in Hostile Anatomy.

    Barnaure, Isabelle / Kulcsár, Zsolt / Schubert, Tilman

    Clinical neuroradiology

    2022  Volume 33, Issue 1, Page(s) 247–249

    MeSH term(s) Humans ; Aortic Aneurysm, Abdominal/surgery ; Blood Vessel Prosthesis Implantation ; Catheterization ; Blood Vessel Prosthesis ; Treatment Outcome ; Endovascular Procedures ; Stents ; Prosthesis Design
    Language English
    Publishing date 2022-08-29
    Publishing country Germany
    Document type Letter
    ZDB-ID 2234662-4
    ISSN 1869-1447 ; 0939-7116 ; 1869-1439
    ISSN (online) 1869-1447
    ISSN 0939-7116 ; 1869-1439
    DOI 10.1007/s00062-022-01212-8
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    Zs.A 3413: Show issues Location:
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  4. Article ; Online: Single antiplatelet regimen in flow diverter treatment of cerebral aneurysms: The drug matters. A systematic review and meta-analysis.

    Ma, Yihui / Madjidyar, Jawid / Schubert, Tilman / Thurner, Patrick / Barnaure, Isabelle / Kulcsar, Zsolt

    Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences

    2023  , Page(s) 15910199231177745

    Abstract: Background: Hemorrhagic and thromboembolic complications (TECs) are the main concerns in the endovascular treatment of intracranial aneurysms using flow diverter devices (FDs). The clinical demand for single antiplatelet therapy (SAPT) is increasing ... ...

    Abstract Background: Hemorrhagic and thromboembolic complications (TECs) are the main concerns in the endovascular treatment of intracranial aneurysms using flow diverter devices (FDs). The clinical demand for single antiplatelet therapy (SAPT) is increasing especially with the development of devices with lower thrombogenicity profile. However, the safety of SAPT is not well established.
    Objective: To analyze the safety and efficacy of SAPT in terms of ischemic and hemorrhagic complications in patients undergoing FDs treatment for cerebral aneurysms.
    Methods: A systematic literature search and meta-analysis were conducted in PubMed, Ovid MEDLINE, Ovid Embase, and Web of Science from January 2010 until October 2022. Twelve articles which reported SAPT and data on hemorrhagic, TECs, and mortality following FDs treatment were included.
    Results: Overall, the 12 studies involved 237 patients with 295 aneurysms. Five investigated the safety and efficacy of SAPT in 202 unruptured aneurysms. Six studies focused on 57 ruptured aneurysms. One study included both ruptured and unruptured aneurysms. Among the 237 patients, prasugrel was most often used as SAPT in 168 cases (70.9%), followed by aspirin in 42 (17.7%) patients, and by ticagrelor in 27 (11.4%). Overall, the hemorrhagic complication rate was 0.1% (95% CI 0% to 1.8%). The TEC rate was 7.6% (95% CI 1.7% to 16.1%). In the subgroup analysis, the TEC rates of prasugrel monotherapy of 2.4% (95% CI 0% to 9.3%) and ticagrelor monotherapy of 4.2% (95% CI 0.1% to 21.1%) were lower than of aspirin monotherapy 20.2% (95% CI 5.9% to 38.6%). The overall mortality rate was 1.3% (95% CI 0% to 6.1%).
    Conclusion: According to the available data, SAPT regimen in patients undergoing FDs treatment for cerebral aneurysms has an acceptable safety profile, especially with the use of ADP-receptor antagonists.
    Language English
    Publishing date 2023-05-23
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1354913-3
    ISSN 2385-2011 ; 1591-0199 ; 1123-9344
    ISSN (online) 2385-2011
    ISSN 1591-0199 ; 1123-9344
    DOI 10.1177/15910199231177745
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    Zs.A 6325: Show issues Location:
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  5. Book ; Thesis: Bestimmung von Proteinaseinhibitoren mit Hilfe des Lasernephelometers

    Barnaure, Ianina

    1981  

    Language German
    Size 35 gez. Bl.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Muenster, Univ., Diss., 1981
    Note 1 Microfiche
    HBZ-ID HT002636046
    Database Catalogue ZB MED Medicine, Health

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  6. Article: Short- and Long-Term Effects of DBS on Gait in Parkinson's Disease.

    Brozova, Hana / Barnaure, Isabelle / Ruzicka, Evzen / Stochl, Jan / Alterman, Ron / Tagliati, Michele

    Frontiers in neurology

    2021  Volume 12, Page(s) 688760

    Abstract: The aim was to compare the short and long-term effects of subthalamic nucleus (STN) deep brain stimulation (DBS) on gait dysfunction and other cardinal symptoms of Parkinson's disease (PD). Two groups of patients were studied. The first group (short-term ...

    Abstract The aim was to compare the short and long-term effects of subthalamic nucleus (STN) deep brain stimulation (DBS) on gait dysfunction and other cardinal symptoms of Parkinson's disease (PD). Two groups of patients were studied. The first group (short-term DBS,
    Language English
    Publishing date 2021-10-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564214-5
    ISSN 1664-2295
    ISSN 1664-2295
    DOI 10.3389/fneur.2021.688760
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  7. Article: Neuroimaging of acute and chronic unilateral and bilateral thalamic lesions.

    Tuttle, C / Boto, J / Martin, S / Barnaure, I / Korchi, A M / Scheffler, M / Vargas, M I

    Insights into imaging

    2019  Volume 10, Issue 1, Page(s) 24

    Abstract: The thalami are bilateral ovoid grey matter cerebral structures bordering the third ventricle on both sides, which participate in functions such as relaying of sensory and motor signals, regulation of consciousness, and alertness. Pathologies affecting ... ...

    Abstract The thalami are bilateral ovoid grey matter cerebral structures bordering the third ventricle on both sides, which participate in functions such as relaying of sensory and motor signals, regulation of consciousness, and alertness. Pathologies affecting the thalami can be of neoplastic, infectious, vascular, toxic, metabolic, or congenital origin.The purpose of this review is to provide a comprehensive approach to the thalamus focusing on its anatomy, the main pathologies affecting this structure and their radiological semiology on CT and MRI. We will also illustrate the importance of multimodal MR imaging (morphologic sequences, diffusion-weighted imaging, perfusion, spectroscopy) for the diagnosis and treatment of these conditions.
    Language English
    Publishing date 2019-02-22
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 2543323-4
    ISSN 1869-4101
    ISSN 1869-4101
    DOI 10.1186/s13244-019-0700-3
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  8. Article ; Conference proceedings: Role of MR Imaging in Complex Regional Pain Syndrome Revisited

    Agten, C. A. / Kobe, A. / Barnaure, I. / Galley, J. / Pfirrmann, C. W. A. / Brunner, F.

    Seminars in Musculoskeletal Radiology

    2019  Volume 23, Issue S 02

    Event/congress 26th Annual Scientific Meeting of the European Society of Musculoskeletal Radiology (ESSR), Lisbon, Portugal, 2019-06-26
    Language English
    Publishing date 2019-06-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 1360919-1
    ISSN 1098-898X ; 1089-7860
    ISSN (online) 1098-898X
    ISSN 1089-7860
    DOI 10.1055/s-0039-1692568
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    Zs.A 4887: Show issues Location:
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  9. Article ; Online: MRI of complex regional pain syndrome in the foot.

    Agten, Christoph A / Kobe, Adrian / Barnaure, Isabelle / Galley, Julien / Pfirrmann, Christian W / Brunner, Florian

    European journal of radiology

    2020  Volume 129, Page(s) 109044

    Abstract: Purpose: To evaluate the diagnostic potential of MRI in patients with suspected CRPS (complex regional pain syndrome).: Method: A retrospective health-record search was conducted for patients with suspected CRPS (foot). Fifty patients with initially ... ...

    Abstract Purpose: To evaluate the diagnostic potential of MRI in patients with suspected CRPS (complex regional pain syndrome).
    Method: A retrospective health-record search was conducted for patients with suspected CRPS (foot). Fifty patients with initially suspected CRPS were included (37 females (51 ± 13 years) and 13 males (44 ± 15 years)). All patients underwent MRI. Two radiologists assessed skin, bone, and soft tissue parameters on MRI. The final diagnosis was CRPS (Gold standard: Budapest criteria) or non-CRPS. MRI parameters were compared between CRPS patients and non-CRPS patients.
    Results: CRPS was diagnosed in 22/50(44 %) patients. Skin thickness (1.9 ± 0.5 mm vs. 1.7 ± 0.3 mm, p = 0.399), enhancement, and subcutaneous edema showed no differences between CRPS and non-CRPS patients. Bone marrow edema presence and pattern were not different between groups. Up to 50 % of CRPS patients showed no bone marrow edema. Subcortical enhancement and periosteal enhancement were not different between groups. For reader 1, muscle edema score was higher in the non-CRPS group compared to the CRPS group (0.1 ± 0.2 vs. 0.6 ± 1.0, p = 0.008), but not different for reader 2 (0.1 ± 0.5 vs. 0.2 ± 0.8, p = 0.819). Perfusion pattern was more extensive in non-CRPS patients for reader 1 (p = 0.048), but not for reader 2 (p = 0.157). Joint effusions showed no difference between groups.
    Conclusions: MRI cannot distinguish between CRPS and non-CRPS patients. The role of MR imaging in patients with suspected CRPS is to exclude alternative diagnoses that would better explain patients' symptoms.
    MeSH term(s) Bone Marrow Diseases/diagnostic imaging ; Complex Regional Pain Syndromes/diagnostic imaging ; Female ; Foot/diagnostic imaging ; Humans ; Magnetic Resonance Imaging ; Male ; Retrospective Studies
    Language English
    Publishing date 2020-05-06
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 138815-0
    ISSN 1872-7727 ; 0720-048X
    ISSN (online) 1872-7727
    ISSN 0720-048X
    DOI 10.1016/j.ejrad.2020.109044
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  10. Article ; Online: Ultra-High-Resolution Time-of-Flight MR-Angiography for the Noninvasive Assessment of Intracranial Aneurysms, Alternative to Preinterventional DSA?

    Schubert, Tilman / Husain, Hakim Shakir / Thurner, Patrick / Madjidyar, Jawid / Barnaure, Isabelle / Piccirelli, Marco / Klarhöfer, Markus / Schmidt, Michaela / Speier, Peter / Forman, Christoph / Kulcsar, Zsolt

    Clinical neuroradiology

    2023  Volume 33, Issue 4, Page(s) 1115–1122

    Abstract: Purpose: The 3D time-of-flight (TOF) magnetic resonance angiography (MRA) at 3T shows high sensitivity for intracranial aneurysms but is inferior to three-dimensional digital subtraction angiography (3D-DSA) regarding aneurysm characteristics. We ... ...

    Abstract Purpose: The 3D time-of-flight (TOF) magnetic resonance angiography (MRA) at 3T shows high sensitivity for intracranial aneurysms but is inferior to three-dimensional digital subtraction angiography (3D-DSA) regarding aneurysm characteristics. We applied an ultra-high-resolution (UHR) TOF-MRA using compressed sensing reconstruction to investigate the diagnostic performance in preinterventional evaluation of intracranial aneurysms compared to conventional TOF-MRA and 3D-DSA.
    Methods: In this study 17 patients with unruptured intracranial aneurysms were included. Aneurysm dimensions, configuration, image quality and sizing of endovascular devices were compared between conventional TOF-MRA at 3T and UHR-TOF with 3D-DSA as gold standard. Quantitatively, contrast-to-noise ratios (CNR) were compared between TOF-MRAs.
    Results: On 3D-DSA, 25 aneurysms in 17 patients were detected. On conventional TOF, 23 aneurysms were detected (sensitivity: 92.6%). On UHR-TOF, 25 aneurysms were detected (sensitivity: 100%). Image quality was not significantly different between TOF and UHR-TOF (p = 0.17). Aneurysm dimension measurements were significantly different between conventional TOF (3.89 mm) and 3D-DSA (4.2 mm, p = 0.08) but not between UHR-TOF (4.12 mm) and 3D-DSA (p = 0.19). Irregularities and small vessels at the aneurysm neck were more frequently correctly depicted on UHR-TOF compared to conventional TOF. Comparison of the planned framing coil diameter and flow-diverter (FD) diameter revealed neither a statistically significant difference between TOF and 3D-DSA (coil p = 0.19, FD p = 0.45) nor between UHR-TOF and 3D-DSA (coil: p = 0.53, FD 0.33). The CNR was significantly higher in conventional TOF (p = 0.009).
    Conclusion: In this pilot study, ultra-high-resolution TOF-MRA visualized all aneurysms and accurately depicted aneurysm irregularities and vessels at the base of the aneurysm comparably to DSA, outperforming conventional TOF. UHR-TOF with compressed sensing reconstruction seems to represent a non-invasive alternative to pre-interventional DSA for intracranial aneurysms.
    MeSH term(s) Humans ; Intracranial Aneurysm/pathology ; Follow-Up Studies ; Pilot Projects ; Magnetic Resonance Angiography/methods ; Angiography, Digital Subtraction/methods ; Sensitivity and Specificity ; Embolization, Therapeutic
    Language English
    Publishing date 2023-07-04
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2234662-4
    ISSN 1869-1447 ; 0939-7116 ; 1869-1439
    ISSN (online) 1869-1447
    ISSN 0939-7116 ; 1869-1439
    DOI 10.1007/s00062-023-01320-z
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