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  1. Article: Ethical Challenges in Clinical Research During the COVID-19 Pandemic.

    Bierer, B E / White, S A / Barnes, J M / Gelinas, L

    Journal of bioethical inquiry

    2020  Volume 17, Issue 4, Page(s) 717–722

    Abstract: The sudden emergence of the COVID-19 pandemic brought global disruption to every aspect of society including healthcare, supply chain, the economy, and social interaction. Among the many emergent considerations were the safety and public health of the ... ...

    Abstract The sudden emergence of the COVID-19 pandemic brought global disruption to every aspect of society including healthcare, supply chain, the economy, and social interaction. Among the many emergent considerations were the safety and public health of the public, patients, essential workers, and healthcare professionals. In certain locations, clinical research was halted-or terminated-in deference to the immediate needs of patient care, and clinical trials focusing on the treatment and prevention of coronavirus infection were prioritized over studies focusing on other diseases. Difficult decisions were made rapidly; flexibility and reconsideration were necessary not only because the intensity and severity of infection varied over time and by locale but also because knowledge of the disease and understanding of its treatment (and prevention) grew. Here we discuss the ethical challenges in decision-making and competing ethical tensions during the pandemic in an effort to advance future preparedness.
    MeSH term(s) COVID-19 ; Clinical Studies as Topic/ethics ; Humans ; Pandemics ; Patient Safety ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-11-09
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2253038-1
    ISSN 1872-4353 ; 1176-7529
    ISSN (online) 1872-4353
    ISSN 1176-7529
    DOI 10.1007/s11673-020-10045-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Penicillin and B-anthracis.

    BARNES, J M

    The Journal of pathology and bacteriology

    2010  Volume 59, Issue 1-2, Page(s) 113–125

    MeSH term(s) Anthrax ; Bacillus anthracis ; Humans ; Penicillins
    Chemical Substances Penicillins
    Language English
    Publishing date 2010-01-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 3101-x
    ISSN 1555-2039 ; 0368-3494
    ISSN (online) 1555-2039
    ISSN 0368-3494
    DOI 10.1002/path.1700590113
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Effect of mass of inoculum on virulence of bacteria injected intraperitoneally in mice.

    BARNES, J M

    Lancet (London, England)

    2009  Volume 2, Issue 6465, Page(s) 127

    MeSH term(s) Animals ; Bacteria/pathogenicity ; Mice ; Virulence
    Language English
    Publishing date 2009-10-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0140-6736 ; 0023-7507
    ISSN (online) 1474-547X
    ISSN 0140-6736 ; 0023-7507
    DOI 10.1016/s0140-6736(47)90195-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Experiments made to determine the toxicity of beryllium.

    BARNES, J M

    Le Medecin d'usine; revue d'hygiene industrielle et des maladies professionnelles

    2007  Volume 11, Issue 8, Page(s) 490

    Title translation Des expériences faites pour déterminer la toxicité du béryllium.
    MeSH term(s) Beryllium/toxicity
    Chemical Substances Beryllium (OW5102UV6N)
    Language French
    Publishing date 2007-12-15
    Publishing country France
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Ethical Challenges in Clinical Research During the COVID-19 Pandemic

    Bierer, B E / White, S A / Barnes, J M / Gelinas, L

    J. bioeth. inq

    Abstract: The sudden emergence of the COVID-19 pandemic brought global disruption to every aspect of society including healthcare, supply chain, the economy, and social interaction. Among the many emergent considerations were the safety and public health of the ... ...

    Abstract The sudden emergence of the COVID-19 pandemic brought global disruption to every aspect of society including healthcare, supply chain, the economy, and social interaction. Among the many emergent considerations were the safety and public health of the public, patients, essential workers, and healthcare professionals. In certain locations, clinical research was halted-or terminated-in deference to the immediate needs of patient care, and clinical trials focusing on the treatment and prevention of coronavirus infection were prioritized over studies focusing on other diseases. Difficult decisions were made rapidly; flexibility and reconsideration were necessary not only because the intensity and severity of infection varied over time and by locale but also because knowledge of the disease and understanding of its treatment (and prevention) grew. Here we discuss the ethical challenges in decision-making and competing ethical tensions during the pandemic in an effort to advance future preparedness.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #917145
    Database COVID19

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  6. Article: The effect of dinitro-o-cresol on the deposition of liver glycogen in the rat.

    BARNES, J M

    The Biochemical journal

    2003  Volume 54, Issue 1, Page(s) 148–153

    MeSH term(s) Animals ; Cresols/analogs & derivatives ; Glycogen/metabolism ; Glycogenolysis ; Liver/metabolism ; Liver Glycogen ; Rats
    Chemical Substances Cresols ; Liver Glycogen ; Glycogen (9005-79-2) ; cresol (GF3CGH8D7Z) ; 2-cresol (YW84DH5I7U)
    Language English
    Publishing date 2003-07-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2969-5
    ISSN 1470-8728 ; 0264-6021 ; 0006-2936 ; 0306-3275
    ISSN (online) 1470-8728
    ISSN 0264-6021 ; 0006-2936 ; 0306-3275
    DOI 10.1042/bj0540148
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Antitoxin transfer from mother to foetus in the guinea-pig.

    BARNES, J M

    The Journal of pathology and bacteriology

    2003  Volume 77, Issue 2, Page(s) 371–380

    MeSH term(s) Antitoxins ; Female ; Fetus ; Guinea Pigs ; Immune Sera ; Mothers ; Pregnancy/physiology
    Chemical Substances Antitoxins ; Immune Sera
    Language English
    Publishing date 2003-08-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 3101-x
    ISSN 1555-2039 ; 0368-3494
    ISSN (online) 1555-2039
    ISSN 0368-3494
    DOI 10.1002/path.1700770206
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: The potential toxicity of chemicals used in food technology.

    BARNES, J M

    The Proceedings of the Nutrition Society

    2003  Volume 15, Issue 2, Page(s) 148–154

    MeSH term(s) Food ; Food Technology ; Humans
    Language English
    Publishing date 2003-08-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 391142-1
    ISSN 1475-2719 ; 0029-6651
    ISSN (online) 1475-2719
    ISSN 0029-6651
    DOI 10.1079/pns19560031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Health hazards from insecticides.

    BARNES, J M

    British medical bulletin

    2003  Volume 7, Issue 1-2, Page(s) 23–27

    MeSH term(s) Hazardous Substances ; Humans ; Insecticides ; Occupational Health
    Chemical Substances Hazardous Substances ; Insecticides
    Language English
    Publishing date 2003-07-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 213294-1
    ISSN 1471-8391 ; 0007-1420
    ISSN (online) 1471-8391
    ISSN 0007-1420
    DOI 10.1093/oxfordjournals.bmb.a073793
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: The action of some synthetic insecticides on mammals.

    BARNES, J M

    Transactions of the Royal Society of Tropical Medicine and Hygiene

    2003  Volume 46, Issue 3, Page(s) 264–270

    MeSH term(s) Animals ; Insecticides/toxicity ; Mammals
    Chemical Substances Insecticides
    Language English
    Publishing date 2003-07-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 441375-1
    ISSN 1878-3503 ; 0035-9203
    ISSN (online) 1878-3503
    ISSN 0035-9203
    DOI 10.1016/0035-9203(52)90074-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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