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  1. Book: CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2011-2015

    Ostrom, Quinn T. / Gittleman, Haley / Truitt, Gabrielle / Boscia, Alexander / Barnholtz-Sloan, Jill S. / Kruchko, Carol

    (Neuro-oncology ; volume 20, supplement 4 (October 2018))

    2018  

    Institution CBTRUS
    Author's details Quinn T. Ostrom, PhD., M.P.H.; Haley Gittleman, M.S.; Gabrielle Truitt, B.S., Alexander Boscia, B.S., Carol Kruchko, B.A.; Jill S. Barnholtz-Sloan, Ph.D
    Series title Neuro-oncology ; volume 20, supplement 4 (October 2018)
    Neuro-Oncology
    Collection Neuro-Oncology
    Language English
    Size iv87 Seiten, Diagramme, Karten
    Publisher Oxford University Press
    Publishing place Cary, NC
    Publishing country United States
    Document type Book
    HBZ-ID HT019950172
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Maximizing Cancer Data-The Future of Cancer Is Now.

    Barnholtz-Sloan, Jill S

    JAMA oncology

    2022  Volume 8, Issue 8, Page(s) 1095–1096

    MeSH term(s) Forecasting ; Humans ; Neoplasms/epidemiology ; Neoplasms/therapy
    Language English
    Publishing date 2022-05-26
    Publishing country United States
    Document type Journal Article
    ISSN 2374-2445
    ISSN (online) 2374-2445
    DOI 10.1001/jamaoncol.2022.1572
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Expanding our knowledge of brain tumor overall survival trends at a global scale.

    Barnholtz-Sloan, Jill S

    Neuro-oncology

    2022  Volume 25, Issue 3, Page(s) 607–608

    MeSH term(s) Humans ; Child ; Brain Neoplasms ; Global Health
    Language English
    Publishing date 2022-12-14
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 2028601-6
    ISSN 1523-5866 ; 1522-8517
    ISSN (online) 1523-5866
    ISSN 1522-8517
    DOI 10.1093/neuonc/noac268
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book ; Online: Novel Approaches to the Analysis of Family Data in Genetic Epidemiology

    Elston, Robert C. / Morris, Nathan / Barnholtz-Sloan, Jill S. / Sun, Xiangqing

    2016  

    Abstract: Genome-wide association studies (GWAS) for complex disorders with large case-control populations have been performed on hundreds of traits in more than 1200 published studies (http://www.genome.gov/gwastudies/) but the variants detected by GWAS account ... ...

    Abstract Genome-wide association studies (GWAS) for complex disorders with large case-control populations have been performed on hundreds of traits in more than 1200 published studies (http://www.genome.gov/gwastudies/) but the variants detected by GWAS account for little of the heritability of these traits, leading to an increasing interest in using family based designs. While GWAS studies are designed to find common variants with low to moderate attributable risks, family based studies are expected to find rare variants with high attributable risk. Because family-based designs can better control both genetic and environmental background, this study design is robust to heterogeneity and population stratification. Moreover, in family-based analysis, the background genetic variation can be modeled to control the residual variance which could increase the power to identify disease associated rare variants. Analysis of families can also help us gain knowledge about disease transmission and inheritance patterns. Although a family-based design has the advantage of being robust to false positives, novel and powerful methods to analyze families in genetic epidemiology continue to be needed, especially for the interaction between genetic and environmental factors associated with disease. Moreover, with the rapid development of sequencing technology, advances in approaches to the design and analysis of sequencing data in families are also greatly needed. The 11 articles in this book all introduce new methodology and, using family data, substantial new findings are presented in the areas of infectious diseases, diabetes, eye traits, autism spectrum disorder and prostate cancer
    Keywords Science (General) ; Genetics
    Size 1 electronic resource (84 p.)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT020090652
    ISBN 9782889199327 ; 2889199320
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Book: CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2010-2014

    Ostrom, Quinn T. / Gittleman, Haley / Liao, Peter / Vecchione-Koval, Toni / Wolinsky, Yingli / Kruchko, Carol / Barnholtz-Sloan, Jill S.

    (Neuro-oncology ; volume 19, supplement 5 (October 2017))

    2017  

    Institution CBTRUS
    Author's details Quinn T. Ostrom, M.A., M.P.H.; Haley Gittleman, M.S.; Peter Liao, B.S.; Toni Vecchione-Koval; Yingli Wolinsky, Ph.D., M.B.A.; Carol Kruchko, B.A.; Jill S. Barnholtz-Sloan, Ph.D
    Series title Neuro-oncology ; volume 19, supplement 5 (October 2017)
    Neuro-Oncology
    Collection Neuro-Oncology
    Language English
    Size v89 Seiten, Illustrationen
    Publisher Oxford University Press
    Publishing place Cary, NC
    Publishing country United States
    Document type Book
    HBZ-ID HT019602702
    Database Catalogue ZB MED Medicine, Health

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  6. Book: CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2009-2013

    Ostrom, Quinn T. / Gittleman, Haley / Xu, Jordan / Kromer, Courtney / Wolinsky, Yingli / Kruchko, Carol / Barnholtz-Sloan, Jill S.

    (Neuro-oncology ; volume 18, supplement 5 (2016))

    2016  

    Institution CBTRUS
    Author's details Quinn T. Ostrom, M.A., M.P.H.; Haley Gittleman, M.S.; Jordan Xu, B.A.; Courtney Kromer, M.S.; Yingli Wolinsky, Ph.D., M.B.A.; Carol Kruchko, B.A.; Jill S. Barnholtz-Sloan, Ph.D
    Series title Neuro-oncology ; volume 18, supplement 5 (2016)
    Neuro-Oncology
    Collection Neuro-Oncology
    Language English
    Size v76 Seiten
    Publisher Oxford University Press
    Publishing place Cary, NC
    Publishing country United States
    Document type Book
    HBZ-ID HT019195906
    Database Catalogue ZB MED Medicine, Health

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  7. Article ; Online: Brain and central nervous system tumor statistics: access to accurate data for all countries is critical!

    Barnholtz-Sloan, Jill S

    Neuro-oncology

    2019  Volume 21, Issue 3, Page(s) 291–292

    MeSH term(s) Brain ; Canada ; Central Nervous System Neoplasms ; Humans
    Language English
    Publishing date 2019-02-01
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2028601-6
    ISSN 1523-5866 ; 1522-8517
    ISSN (online) 1523-5866
    ISSN 1522-8517
    DOI 10.1093/neuonc/noy205
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Critical Partnerships: How to Develop a Trans-Disciplinary Research Team.

    Waite, Kristin A / Pronovost, Peter J / Barnholtz-Sloan, Jill S

    Cancers

    2023  Volume 15, Issue 20

    Abstract: Trans-disciplinary science will continue to be critical for the next wave of scientific advancement to fully understand cancer development, progression, and treatment. The shift from the independent investigator to either leading or being a productive ... ...

    Abstract Trans-disciplinary science will continue to be critical for the next wave of scientific advancement to fully understand cancer development, progression, and treatment. The shift from the independent investigator to either leading or being a productive member of a scientific team can be successful by focusing on some key elements that can build and strengthen interactions with a diverse group of people. These include the selection of the team, communication, leadership and mentorship, shared goals, responsibility to the team, authorship, and proactively dealing with conflict. While there are extensive books written on developing teams in the business world, and larger pieces in the medical arena, we attempt to provide here a concise, high-level view as a starting point for those that may be moving from being an independent researcher and are developing their own, larger, trans-disciplinary teams.
    Language English
    Publishing date 2023-10-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers15205078
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Treatment Outcomes for Primary Hepatic Angiosarcoma: National Cancer Database Analysis 2004-2014.

    Mangla, Ankit / Cioffi, Gino / Barnholtz-Sloan, Jill S / Lee, Richard T

    Current oncology (Toronto, Ont.)

    2022  Volume 29, Issue 5, Page(s) 3637–3646

    Abstract: Background: To determine the risk of mortality and factors associated with survival amongst patients diagnosed with primary hepatic angiosarcoma (PHA). Methods: All patients diagnosed with hepatocellular carcinoma (HCC) or PHA from 2004 to 2014 were ... ...

    Abstract Background: To determine the risk of mortality and factors associated with survival amongst patients diagnosed with primary hepatic angiosarcoma (PHA). Methods: All patients diagnosed with hepatocellular carcinoma (HCC) or PHA from 2004 to 2014 were identified from the National Cancer Database (NCDB). Further analysis was performed within the cohort of patients with PHA to assess the impact of surgery, chemotherapy, radiation, and facility type on overall survival (OS). A multivariable analysis using the Cox proportional methods and a survival analysis using the Kaplan−Meier method were used. Results: A total of 117,633 patients with HCC were identified, out of whom 346 patients had PHA. Patients with PHA had a mean age of 62.9 years (SD 13.7), the majority were men (64.7%), white (85.8%), and had a Charlson comorbidity index (CCI) of zero (66.2%). A third of the patients with PHA (35.7%) received chemotherapy, and 14.6% underwent a surgical resection. The median survival was 1.9 months (1.8−2.4 months) compared to patients with HCC (10.4 months, 10.2−10.5) (aHR-2.41, 95% CI: 2.10−2.77, p < 0.0001). Surgical resection was associated with a higher median survival (7.7 versus 1.8 months, aHR-0.23, 95% CI: 0.15−0.37, p < 0.0001). A receipt of chemotherapy was associated with a higher median survival than no chemotherapy (5.1 versus 1.2 months, aHR-0.44, 95% CI: 0.32−0.60, p < 0.0001), although the survival benefit did not persist long term. Conclusion: PHA is associated with poor outcomes. A surgical resection and chemotherapy are associated with improved survival outcomes; however, the long-term benefits of chemotherapy are limited.
    MeSH term(s) Carcinoma, Hepatocellular/therapy ; Female ; Hemangiosarcoma/therapy ; Humans ; Liver Neoplasms/surgery ; Male ; Middle Aged ; Retrospective Studies ; Treatment Outcome
    Language English
    Publishing date 2022-05-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1236972-x
    ISSN 1718-7729 ; 1198-0052
    ISSN (online) 1718-7729
    ISSN 1198-0052
    DOI 10.3390/curroncol29050292
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Sex differences in glioblastoma response to treatment: Impact of MGMT methylation.

    Cioffi, Gino / Waite, Kristin A / Dmukauskas, Mantas / Glantz, Michael / Aulakh, Sonikpreet / Nicolaides, Theodore / Sengupta, Soma / Xiu, Joanne / Barnholtz-Sloan, Jill S

    Neuro-oncology advances

    2024  Volume 6, Issue 1, Page(s) vdae031

    Language English
    Publishing date 2024-03-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 3009682-0
    ISSN 2632-2498 ; 2632-2498
    ISSN (online) 2632-2498
    ISSN 2632-2498
    DOI 10.1093/noajnl/vdae031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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