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  1. Article ; Online: Efficiency Fluctuations in a Quantum Battery Charged by a Repeated Interaction Process.

    Barra, Felipe

    Entropy (Basel, Switzerland)

    2022  Volume 24, Issue 6

    Abstract: A repeated interaction process assisted by auxiliary thermal systems charges a quantum battery. The charging energy is supplied by switching on and off the interaction between the battery and the thermal systems. The charged state is an equilibrium state ...

    Abstract A repeated interaction process assisted by auxiliary thermal systems charges a quantum battery. The charging energy is supplied by switching on and off the interaction between the battery and the thermal systems. The charged state is an equilibrium state for the repeated interaction process, and the ergotropy characterizes its charge. The working cycle consists in extracting the ergotropy and charging the battery again. We discuss the fluctuating efficiency of the process, among other fluctuating properties. These fluctuations are dominated by the equilibrium distribution and depend weakly on other process properties.
    Language English
    Publishing date 2022-06-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2014734-X
    ISSN 1099-4300 ; 1099-4300
    ISSN (online) 1099-4300
    ISSN 1099-4300
    DOI 10.3390/e24060820
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  2. Article ; Online: Dissipative Charging of a Quantum Battery.

    Barra, Felipe

    Physical review letters

    2019  Volume 122, Issue 21, Page(s) 210601

    Abstract: We show that a cyclic unitary process can extract work from the thermodynamic equilibrium state of an engineered quantum dissipative process. Systems in the equilibrium states of these processes serve as batteries, storing energy. The dissipative process ...

    Abstract We show that a cyclic unitary process can extract work from the thermodynamic equilibrium state of an engineered quantum dissipative process. Systems in the equilibrium states of these processes serve as batteries, storing energy. The dissipative process that brings the battery to the active equilibrium state is driven by an agent that couples the battery to thermal systems. The second law of thermodynamics imposes a work cost for the process; however, no work is needed to keep the battery in that charged state. We consider simple examples of these batteries and discuss situations in which the charged state has full population inversion, in which case the extractable work is maximal, and circumstances in which the efficiency of the process is maximal.
    Language English
    Publishing date 2019-07-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.122.210601
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  3. Article ; Online: Letter to "Increased risk of placenta previa and preterm birth in pregnant women with endometriosis/adenomyosis: A propensity-score matching analysis of a nationwide perinatal database in Japan".

    Barra, Fabio / Izzotti, Alberto / Bogliolo, Stefano

    The journal of obstetrics and gynaecology research

    2024  

    Language English
    Publishing date 2024-03-07
    Publishing country Australia
    Document type Letter
    ZDB-ID 1327307-3
    ISSN 1447-0756 ; 1341-8076
    ISSN (online) 1447-0756
    ISSN 1341-8076
    DOI 10.1111/jog.15915
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    Zs.A 1810: Show issues Location:
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  4. Article ; Online: Experimental and new investigational drugs for the treatment of uterine fibroids.

    Evangelisti, Giulio / Ferrero, Simone / Perrone, Umberto / Gustavino, Claudio / Volpi, Eugenio / Izzotti, Alberto / Barra, Fabio

    Expert opinion on investigational drugs

    2024  , Page(s) 1–12

    Abstract: Introduction: Uterine fibroids, the most prevalent benign tumors among reproductive-age women, pose treatment challenges that range from surgical interventions to medical therapies for symptom control. Progestins and estroprogestins effectively manage ... ...

    Abstract Introduction: Uterine fibroids, the most prevalent benign tumors among reproductive-age women, pose treatment challenges that range from surgical interventions to medical therapies for symptom control. Progestins and estroprogestins effectively manage uterine bleeding by suppressing dysfunctional endometrium over fibroids. While GnRH agonists represent a crucial milestone in symptom treatment, their prolonged use results in menopausal-like symptoms and irreversible bone mineral density loss. Advancements in understanding fibroid pathophysiology have prompted the exploration of new compounds to overcome current therapy limitations.
    Areas covered: This manuscript offers an updated overview of investigational drugs for symptomatic uterine fibroids.
    Expert opinion: Despite ulipristal acetate's well-established efficacy as a selective progesterone receptor modulator (SPRM) in fibroid treatment, its prescription has declined due to the rare but severe risk of liver damage. Oral GnRH antagonists, like elagolix, relugolix, and linzagolix, with their novel pharmacodynamic properties, are gaining traction in fibroid management, inducing a dose-dependent reduction in circulating sex hormone levels. Ongoing research on natural compounds, such as vitamin D and epigallocatechin gallate (EGCG), presents emerging options for treating uterine fibroids. This evolving landscape reflects the ongoing efforts to improve therapeutic outcomes for individuals with symptomatic uterine fibroids.
    Language English
    Publishing date 2024-04-17
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1182884-5
    ISSN 1744-7658 ; 0967-8298 ; 1354-3784
    ISSN (online) 1744-7658
    ISSN 0967-8298 ; 1354-3784
    DOI 10.1080/13543784.2024.2343786
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3739: Show issues Location:
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  5. Article ; Online: Thermalization and Dephasing in Collisional Reservoirs.

    Tabanera-Bravo, Jorge / Parrondo, Juan M R / Esposito, Massimiliano / Barra, Felipe

    Physical review letters

    2023  Volume 130, Issue 20, Page(s) 200402

    Abstract: We introduce a wide class of quantum maps that arise in collisional reservoirs and are able to thermalize a system if they operate in conjunction with an additional dephasing mechanism. These maps describe the effect of collisions and induce transitions ... ...

    Abstract We introduce a wide class of quantum maps that arise in collisional reservoirs and are able to thermalize a system if they operate in conjunction with an additional dephasing mechanism. These maps describe the effect of collisions and induce transitions between populations that obey detailed balance, but also create coherences that prevent the system from thermalizing. We combine these maps with a unitary evolution acting during random Poissonian times between collisions and causing dephasing. We find that, at a low collision rate, the nontrivial combination of these two effects causes thermalization in the system. This scenario is suitable for modeling collisional reservoirs at equilibrium. We justify this claim by identifying the conditions for such maps to arise within a scattering theory approach and provide a thorough characterization of the resulting thermalization process.
    Language English
    Publishing date 2023-06-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.130.200402
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  6. Article ; Online: Exploring the Safety Profile of Ornidazole as Drug Candidate for Endometriosis Treatment.

    Barra, Fabio / Perrone, Umberto / Iasci, Angela / Ferrero, Simone / Bogliolo, Stefano

    Gynecologic and obstetric investigation

    2023  Volume 88, Issue 3, Page(s) 185–186

    MeSH term(s) Female ; Humans ; Ornidazole/adverse effects ; Endometriosis/drug therapy
    Chemical Substances Ornidazole (62XCK0G93T)
    Language English
    Publishing date 2023-04-04
    Publishing country Switzerland
    Document type Letter ; Comment
    ZDB-ID 800003-7
    ISSN 1423-002X ; 0378-7346
    ISSN (online) 1423-002X
    ISSN 0378-7346
    DOI 10.1159/000530461
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 688: Show issues Location:
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  7. Article ; Online: The thermodynamic cost of driving quantum systems by their boundaries.

    Barra, Felipe

    Scientific reports

    2015  Volume 5, Page(s) 14873

    Abstract: The laws of thermodynamics put limits to the efficiencies of thermal machines. Analogues of these laws are now established for quantum engines weakly and passively coupled to the environment providing a framework to find improvements to their performance. ...

    Abstract The laws of thermodynamics put limits to the efficiencies of thermal machines. Analogues of these laws are now established for quantum engines weakly and passively coupled to the environment providing a framework to find improvements to their performance. Systems whose interaction with the environment is actively controlled do not fall in that framework. Here we consider systems actively and locally coupled to the environment, evolving with a so-called boundary-driven Lindblad equation. Starting from a unitary description of the system plus the environment we simultaneously obtain the Lindblad equation and the appropriate expressions for heat, work and entropy-production of the system extending the framework for the analysis of new, and some already proposed, quantum heat engines. We illustrate our findings in spin 1/2 chains and explain why an XX chain coupled in this way to a single heat bath relaxes to thermodynamic-equilibrium while and XY chain does not. Additionally, we show that an XX chain coupled to a left and a right heat baths behaves as a quantum engine, a heater or refrigerator depending on the parameters, with efficiencies bounded by Carnot efficiencies.
    Language English
    Publishing date 2015-10-08
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/srep14873
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  8. Article: Elagolix sodium for the treatment of women with moderate to severe endometriosis-associated pain.

    Barra, F / Scala, C / Ferrero, S

    Drugs of today (Barcelona, Spain : 1998)

    2019  Volume 55, Issue 4, Page(s) 237–246

    Abstract: First-line medical therapies for treating pain associated with endometriosis mainly consist in combined oral contraceptives and progestins. However, some women, having persistence of symptoms, may require further therapeutic options. Among these, ... ...

    Abstract First-line medical therapies for treating pain associated with endometriosis mainly consist in combined oral contraceptives and progestins. However, some women, having persistence of symptoms, may require further therapeutic options. Among these, gonadotropin-releasing hormone (GnRH) agonists (GnRH-as) have been widely employed in the last 30 years, despite being characterized by an unfavorable safety profile. Currently, new alternative investigational options are being investigated to treat this benign chronic disease. GnRH antagonists (GnRH-ants) are innovative hormonal drugs that do not induce flare-up effects and present also a limited onset of hypoestrogenic symptoms; in fact, their pharmacological mechanism of action, which consists in pure antagonistic activity, differs from that of traditional GnRH-as. In July 2018, the U.S. Food and Drug Administration (FDA) approved elagolix sodium for the management of moderate to severe pain associated with endometriosis, after the drug showed promising efficacy and safety results in previous phase III trials. This monograph aims to provide a complete overview of the pharmacokinetics, clinical efficacy and safety of this GnRH-ant for treating patients with endometriosis.
    MeSH term(s) Endometriosis/drug therapy ; Female ; Hormone Antagonists/therapeutic use ; Humans ; Hydrocarbons, Fluorinated/therapeutic use ; Pain/drug therapy ; Pyrimidines/therapeutic use
    Chemical Substances Hormone Antagonists ; Hydrocarbons, Fluorinated ; Pyrimidines ; elagolix (5B2546MB5Z)
    Language English
    Publishing date 2019-05-03
    Publishing country Spain
    Document type Journal Article ; Review
    ISSN 1699-3993
    ISSN 1699-3993
    DOI 10.1358/dot.2019.55.4.2930713
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  9. Article ; Online: Unbalanced Pro-Inflammatory and Anti-Inflammatory Cytokines Ratio and Endometriosis: A Contributive Pathogenic Role?

    Barra, Fabio / Ferrero, Simone

    Iranian journal of immunology : IJI

    2019  Volume 16, Issue 3, Page(s) 265–267

    MeSH term(s) Clinical Trials as Topic ; Endometriosis/immunology ; Estrogens/genetics ; Estrogens/metabolism ; Female ; Gene Expression Regulation ; Humans ; Inflammation/immunology ; Interferon-gamma/metabolism ; NF-kappa B/metabolism ; Phenotype ; Signal Transduction ; Transforming Growth Factor beta1/metabolism
    Chemical Substances Estrogens ; NF-kappa B ; Transforming Growth Factor beta1 ; Interferon-gamma (82115-62-6)
    Language English
    Publishing date 2019-09-25
    Publishing country Iran
    Document type Letter
    ISSN 1735-367X
    ISSN (online) 1735-367X
    DOI 10.22034/IJI.2019.80277
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  10. Article ; Online: The role of monocytic myeloid-derived suppressor cells in the pathogenesis of endometriosis.

    Barra, Fabio / Ferrero, Simone

    American journal of reproductive immunology (New York, N.Y. : 1989)

    2019  Volume 81, Issue 3, Page(s) e13094

    MeSH term(s) Chemokines, CC ; Endometriosis ; Female ; HLA-DR Antigens ; Humans ; Monocytes ; Myeloid-Derived Suppressor Cells ; Sialic Acid Binding Ig-like Lectin 3
    Chemical Substances CCL25 protein, human ; CD33 protein, human ; Chemokines, CC ; HLA-DR Antigens ; Sialic Acid Binding Ig-like Lectin 3
    Language English
    Publishing date 2019-02-13
    Publishing country Denmark
    Document type Letter ; Comment
    ZDB-ID 604542-x
    ISSN 1600-0897 ; 0271-7352 ; 8755-8920 ; 1046-7408
    ISSN (online) 1600-0897
    ISSN 0271-7352 ; 8755-8920 ; 1046-7408
    DOI 10.1111/aji.13094
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    Zs.A 1653: Show issues Location:
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