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  1. Article ; Online: How seasonality influences the thermal biology of lizards with different thermoregulatory strategies: a meta-analysis.

    Giacometti, Danilo / Palaoro, Alexandre V / Leal, Laura C / de Barros, Fábio C

    Biological reviews of the Cambridge Philosophical Society

    2023  Volume 99, Issue 2, Page(s) 409–429

    Abstract: Ectotherms that maintain thermal balance in the face of varying climates should be able to colonise a wide range of habitats. In lizards, thermoregulation usually appears as a variety of behaviours that buffer external influences over physiology. Basking ...

    Abstract Ectotherms that maintain thermal balance in the face of varying climates should be able to colonise a wide range of habitats. In lizards, thermoregulation usually appears as a variety of behaviours that buffer external influences over physiology. Basking species rely on solar radiation to raise body temperatures and usually show high thermoregulatory precision. By contrast, species that do not bask are often constrained by climatic conditions in their habitats, thus having lower thermoregulatory precision. While much focus has been given to the effects of mean habitat temperatures, relatively less is known about how seasonality affects the thermal biology of lizards on a macroecological scale. Considering the current climate crisis, assessing how lizards cope with temporal variations in environmental temperature is essential to understand better how these organisms will fare under climate change. Activity body temperatures (T
    MeSH term(s) Humans ; Animals ; Lizards/physiology ; Phylogeny ; Body Temperature Regulation ; Temperature ; Biology ; Body Temperature
    Language English
    Publishing date 2023-10-23
    Publishing country England
    Document type Meta-Analysis ; Journal Article
    ZDB-ID 1423558-4
    ISSN 1469-185X ; 0006-3231 ; 1464-7931
    ISSN (online) 1469-185X
    ISSN 0006-3231 ; 1464-7931
    DOI 10.1111/brv.13028
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  2. Article: Mechanisms and consequences of COVID-19 associated liver injury: What can we affirm?

    Brito, Carlos Antunes / Barros, Fabio Marinho / Lopes, Edmundo Pessoa

    World journal of hepatology

    2020  Volume 12, Issue 8, Page(s) 413–422

    Abstract: Since the first reports of coronavirus disease 2019 (COVID-19) cases in December 2019 in China, numerous papers have been published describing a high frequency of liver injury associated with severe acute respiratory syndrome coronavirus 2 infection, ... ...

    Abstract Since the first reports of coronavirus disease 2019 (COVID-19) cases in December 2019 in China, numerous papers have been published describing a high frequency of liver injury associated with severe acute respiratory syndrome coronavirus 2 infection, many of them proposing a link between these findings and patient outcomes. Increases in serum aminotransferase levels (ranging from 16% to 62%) and bilirubin levels (ranging from 5% to 21%) have been reported and seem to be more often observed in patients with severe forms of COVID-19. Although absolute changes in these parameters are frequently seen, other variables, such as the ratio above the upper limit of normal, the onset of liver injury as a complication in severe cases and histopathological findings, reinforce that liver changes are of dubious clinical relevance in the course of this disease. Other factors must also be considered in these analyses, such as the repercussions of hemodynamic changes, the presence of thrombotic events, and, mainly, the possible drug-induced liver injury with the current, yet off-label, treatment. This paper aimed to analyze the currently available data on liver injury in patients with COVID-19.
    Keywords covid19
    Language English
    Publishing date 2020-09-11
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2573703-X
    ISSN 1948-5182
    ISSN 1948-5182
    DOI 10.4254/wjh.v12.i8.413
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  3. Article: Accuracy of imaging grading in comparison to open laminectomy to evaluate pedicle screws positioning.

    Rosa Filezio, Marina / Peiro-Garcia, Alejandro / Parsons, David Llewellyn / Thomas, Kenneth / Ferri-de-Barros, Fabio

    Annals of medicine and surgery (2012)

    2023  Volume 86, Issue 1, Page(s) 199–206

    Abstract: Study design: Prospective experimental study.: Objective: To compare the accuracy of O-Arm-acquired radiographic and computed tomography (CT) evaluation of thoracic pedicle screw placement with open laminectomy in a simulation laboratory.: Summary ... ...

    Abstract Study design: Prospective experimental study.
    Objective: To compare the accuracy of O-Arm-acquired radiographic and computed tomography (CT) evaluation of thoracic pedicle screw placement with open laminectomy in a simulation laboratory.
    Summary of background data: Improving surgical safety and procedural efficiency during thoracic posterior spine instrumentation is essential for decreasing complication rates and possible related risks. The most common way of verifying the position of pedicle screws during the surgical procedure and immediately postoperatively is to acquire intraoperative fluoroscopic images and plain radiographs of the spine, respectively. Laboratory simulated surgery is a valuable tool to evaluate the accuracy of those exams.
    Methods: Twenty simulation models of scoliosis from T3 to T7 were instrumented by five spine fellows (total of 200 pedicle screws), followed by radiographic and CT images acquired with the assistance of the O-Arm which were evaluated by three independent raters. A fellowship-trained spine neurosurgeon performed laminectomies on the instrumented levels and assessed pedicle integrity (gold standard).
    Results: Forty-eight breaches were identified in the axial direct view after laminectomy. Of those, eighteen breaches were classified as unacceptable. Regarding the sagittal direct view, four breaches were observed, three of which were classified as unacceptable. Overall, both O-arm radiographic and CT evaluations had a significantly high negative predicted value but a low positive predicted value to identify unacceptable breaches, especially in the sagittal plane. The frequency of missed breaches by all three examiners was high, particularly in the sagittal plane.
    Conclusion: Postoperative evaluation of pedicle screws using O-arm-acquired radiographic or CT images may underdiagnose the presence of breaches. In our study, sagittal breaches were more difficult to diagnose than axial breaches. Although most breaches do not have clinical repercussions, this study suggests that this modality of postoperative radiographic assessment may be inaccurate.
    Level of evidence: 4.
    Language English
    Publishing date 2023-11-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2745440-X
    ISSN 2049-0801
    ISSN 2049-0801
    DOI 10.1097/MS9.0000000000001515
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  4. Article: Floral glands in myophilous and sapromyophilous species of Pleurothallidinae (Epidendroideae, Orchidaceae)—osmophores, nectaries, and a unique sticky gland

    Arévalo-Rodrigues, Gustavo / de Barros, Fábio / Davis, Arthur R. / Cardoso-Gustavson, Poliana

    Protoplasma. 2021 Sept., v. 258, no. 5

    2021  

    Abstract: Pleurothallidinae orchids have been the focus of many multidisciplinary studies due to their challenging systematics and taxonomy. The synapomorphies already recognized in the group are mostly related to floral characters, the last proposed being the ... ...

    Abstract Pleurothallidinae orchids have been the focus of many multidisciplinary studies due to their challenging systematics and taxonomy. The synapomorphies already recognized in the group are mostly related to floral characters, the last proposed being the occurrence of alkanes in the floral fragrance. The composition of the floral bouquet varied significantly among the studied species, leading us to hypothesize that the variations in volatiles emitted could be linked to the structure of osmophores, especially when comparing the myophilous and sapromyophilous pollination syndromes. Sepals and labellum at different developmental stages of seven Brazilian Pleurothallidinae species were examined using light, scanning, and transmission electron microscopy. Nectar reabsorption was assessed by Lucifer Yellow CH tracer and imaged under confocal microscopy. Nectaries were restricted to the labellum of the myophilous species, whereas osmophores occurred in the dorsal and/or lateral sepals, varying according to species. In the sapromyophilous species, floral nectaries were not detected and osmophores were restricted to the labellum. Osmophore structure was correlated with the volatiles emitted, being the trichome osmophores notably present on the sepals of both myophilous species that possess nectaries. For the first time, we demonstrated reabsorption of the released nectar in Pleurothallidinae and the occurrence of a unique gland named sticky-exudate glands, which occurred in the lateral sepals and labellum of Echinosepala aspasicensis, a sapromyophilous species, that released a heterogeneous exudate composed of polysaccharides and lipids. Similar glands have been reported in Bulbophyllum, highlighting the convergence between both groups.
    Keywords Bulbophyllum ; confocal microscopy ; nectar ; odors ; pollination ; polysaccharides ; resorption ; synapomorphy ; taxonomy ; transmission electron microscopy ; trichomes
    Language English
    Dates of publication 2021-09
    Size p. 1061-1076.
    Publishing place Springer Vienna
    Document type Article
    ZDB-ID 123809-7
    ISSN 1615-6102 ; 0033-183X
    ISSN (online) 1615-6102
    ISSN 0033-183X
    DOI 10.1007/s00709-021-01624-2
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

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  5. Article ; Online: Reinventing the wheel in scoliosis surgery: effective strategies for safely improving efficiency

    Bourget-Murray, Jonathan / Ferri-de-Barros, Fabio

    Canadian journal of surgery. Journal canadien de chirurgie

    2019  Volume 62, Issue 1, Page(s) 7–8

    Abstract: Posterior spinal instrumentation and fusion (PSIF) has been the standard operative treatment for adolescent idiopathic scoliosis (AIS) and is one of the most frequently performed elective pediatric surgeries in North America, incurring an expenditure of ... ...

    Abstract Posterior spinal instrumentation and fusion (PSIF) has been the standard operative treatment for adolescent idiopathic scoliosis (AIS) and is one of the most frequently performed elective pediatric surgeries in North America, incurring an expenditure of more than $1.1 billion annually in the United States alone. This commentary reflects on the outcomes of systematically implementing intraoperative skull femoral traction (IOSFT) combined with navigated sequential drilling (NSD) during PSIF for AIS as strategies for quality improvement at our tertiary children’s hospital.
    MeSH term(s) Adolescent ; Bone Transplantation/methods ; Child ; Cohort Studies ; Female ; Hospitals, Pediatric ; Humans ; Internal Fixators ; Male ; North America ; Quality Improvement ; Retrospective Studies ; Scoliosis/diagnostic imaging ; Scoliosis/surgery ; Severity of Illness Index ; Spinal Fusion/methods ; Traction/methods ; Treatment Outcome
    Language English
    Publishing date 2019-01-28
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 410651-9
    ISSN 1488-2310 ; 0008-428X
    ISSN (online) 1488-2310
    ISSN 0008-428X
    DOI 10.1503/cjs.019317
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 221: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article: Unmet Needs of Surgical Care for Children: A Case Study in the Brazilian Publicly-Financed Health System.

    Bressan-Neto, Mario / Filezio, Marina Rosa / Ferri-de-Barros, Fabio / Defino, Helton Luiz Aparecido

    Revista brasileira de ortopedia

    2021  Volume 56, Issue 3, Page(s) 360–367

    Abstract: ... ...

    Abstract Objective
    Language English
    Publishing date 2021-03-31
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2411301-3
    ISSN 1982-4378 ; 0102-3616
    ISSN (online) 1982-4378
    ISSN 0102-3616
    DOI 10.1055/s-0040-1721836
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  7. Article ; Online: Floral glands in myophilous and sapromyophilous species of Pleurothallidinae (Epidendroideae, Orchidaceae)-osmophores, nectaries, and a unique sticky gland.

    Arévalo-Rodrigues, Gustavo / de Barros, Fábio / Davis, Arthur R / Cardoso-Gustavson, Poliana

    Protoplasma

    2021  Volume 258, Issue 5, Page(s) 1061–1076

    Abstract: Pleurothallidinae orchids have been the focus of many multidisciplinary studies due to their challenging systematics and taxonomy. The synapomorphies already recognized in the group are mostly related to floral characters, the last proposed being the ... ...

    Abstract Pleurothallidinae orchids have been the focus of many multidisciplinary studies due to their challenging systematics and taxonomy. The synapomorphies already recognized in the group are mostly related to floral characters, the last proposed being the occurrence of alkanes in the floral fragrance. The composition of the floral bouquet varied significantly among the studied species, leading us to hypothesize that the variations in volatiles emitted could be linked to the structure of osmophores, especially when comparing the myophilous and sapromyophilous pollination syndromes. Sepals and labellum at different developmental stages of seven Brazilian Pleurothallidinae species were examined using light, scanning, and transmission electron microscopy. Nectar reabsorption was assessed by Lucifer Yellow CH tracer and imaged under confocal microscopy. Nectaries were restricted to the labellum of the myophilous species, whereas osmophores occurred in the dorsal and/or lateral sepals, varying according to species. In the sapromyophilous species, floral nectaries were not detected and osmophores were restricted to the labellum. Osmophore structure was correlated with the volatiles emitted, being the trichome osmophores notably present on the sepals of both myophilous species that possess nectaries. For the first time, we demonstrated reabsorption of the released nectar in Pleurothallidinae and the occurrence of a unique gland named sticky-exudate glands, which occurred in the lateral sepals and labellum of Echinosepala aspasicensis, a sapromyophilous species, that released a heterogeneous exudate composed of polysaccharides and lipids. Similar glands have been reported in Bulbophyllum, highlighting the convergence between both groups.
    MeSH term(s) Flowers ; Microscopy, Electron, Transmission ; Orchidaceae ; Plant Nectar ; Pollination
    Chemical Substances Plant Nectar
    Language English
    Publishing date 2021-02-22
    Publishing country Austria
    Document type Journal Article
    ZDB-ID 123809-7
    ISSN 1615-6102 ; 0033-183X
    ISSN (online) 1615-6102
    ISSN 0033-183X
    DOI 10.1007/s00709-021-01624-2
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2366: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article: Mechanisms and consequences of COVID-19 associated liver injury: What can we affirm?

    Brito, Carlos Antunes / Barros, Fabio Marinho / Lopes, Edmundo Pessoa

    World J. Hepatol.

    Abstract: Since the first reports of coronavirus disease 2019 (COVID-19) cases in December 2019 in China, numerous papers have been published describing a high frequency of liver injury associated with severe acute respiratory syndrome coronavirus 2 infection, ... ...

    Abstract Since the first reports of coronavirus disease 2019 (COVID-19) cases in December 2019 in China, numerous papers have been published describing a high frequency of liver injury associated with severe acute respiratory syndrome coronavirus 2 infection, many of them proposing a link between these findings and patient outcomes. Increases in serum aminotransferase levels (ranging from 16% to 62%) and bilirubin levels (ranging from 5% to 21%) have been reported and seem to be more often observed in patients with severe forms of COVID-19. Although absolute changes in these parameters are frequently seen, other variables, such as the ratio above the upper limit of normal, the onset of liver injury as a complication in severe cases and histopathological findings, reinforce that liver changes are of dubious clinical relevance in the course of this disease. Other factors must also be considered in these analyses, such as the repercussions of hemodynamic changes, the presence of thrombotic events, and, mainly, the possible drug-induced liver injury with the current, yet off-label, treatment. This paper aimed to analyze the currently available data on liver injury in patients with COVID-19.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #782298
    Database COVID19

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  9. Article ; Online: Are chromosome number and genome size associated with habit and environmental niche variables? Insights from the Neotropical orchids.

    Moraes, Ana Paula / Engel, Thaissa Brogliato Junqueira / Forni-Martins, Eliana R / de Barros, Fábio / Felix, Leonardo P / Cabral, Juliano Sarmento

    Annals of botany

    2022  Volume 130, Issue 1, Page(s) 11–25

    Abstract: Background and aims: The entangled relationship of chromosome number and genome size with species distribution has been the subject of study for almost a century, but remains an open question due to previous ecological and phylogenetic knowledge ... ...

    Abstract Background and aims: The entangled relationship of chromosome number and genome size with species distribution has been the subject of study for almost a century, but remains an open question due to previous ecological and phylogenetic knowledge constraints. To better address this subject, we used the clade Maxillariinae, a widely distributed and karyotypically known orchid group, as a model system to infer such relationships in a robust methodological framework.
    Methods: Based on the literature and new data, we gathered the chromosome number and genome size for 93 and 64 species, respectively. We built a phylogenetic hypothesis and assessed the best macroevolutionary model for both genomic traits. Additionally, we collected together ecological data (preferences for bioclimatic variables, elevation and habit) used as explanatory variables in multivariate phylogenetic models explaining genomic traits. Finally, the impact of polyploidy was estimated by running the analyses with and without polyploids in the sample.
    Key results: The association between genomic and ecological data varied depending on whether polyploids were considered or not. Without polyploids, chromosome number failed to present consistent associations with ecological variables. With polyploids, there was a tendency to waive epiphytism and colonize new habitats outside humid forests. The genome size showed association with ecological variables: without polyploids, genome increase was associated with flexible habits, with higher elevation and with drier summers; with polyploids, genome size increase was associated with colonizing drier environments.
    Conclusions: The chromosome number and genome size variations, essential but neglected traits in the ecological niche, are shaped in the Maxillariinae by both neutral and adaptive evolution. Both genomic traits are partially correlated to bioclimatic variables and elevation, even when controlling for phylogenetic constraints. While polyploidy was associated with shifts in the environmental niche, the genome size emerges as a central trait in orchid evolution by the association between small genome size and epiphytism, a key innovation to Neotropical orchid diversification.
    MeSH term(s) Chromosomes ; Genome Size ; Habits ; Orchidaceae/genetics ; Phylogeny ; Polyploidy
    Language English
    Publishing date 2022-02-10
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1461328-1
    ISSN 1095-8290 ; 0305-7364
    ISSN (online) 1095-8290
    ISSN 0305-7364
    DOI 10.1093/aob/mcac021
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  10. Article ; Online: Environmental temperature predicts resting metabolic rates in tropidurinae lizards.

    Giacometti, Danilo / Bars-Closel, Melissa / Kohlsdorf, Tiana / de Carvalho, José Eduardo / Cury de Barros, Fábio

    Journal of experimental zoology. Part A, Ecological and integrative physiology

    2022  Volume 337, Issue 9-10, Page(s) 1039–1052

    Abstract: Interspecific variation in metabolic rates may be associated with climate, habitat structure, and resource availability. Despite a strong link between ecology and physiology, there is a dearth in the understanding of how the costs of body maintenance ... ...

    Abstract Interspecific variation in metabolic rates may be associated with climate, habitat structure, and resource availability. Despite a strong link between ecology and physiology, there is a dearth in the understanding of how the costs of body maintenance change during ecological transitions. We focused on an ecologically diverse group of neotropical lizards (Tropidurinae) to investigate whether and how resting metabolic rate (RMR) evolved under divergent micro- and macrohabitat conditions. Using a phylogenetic framework, we tested whether species from hot and dry habitats had lower RMRs in relation to those from cooler and mesic habitats, and investigated whether microhabitat usage had an effect over body mass-adjusted RMRs. Our results suggest that RMRs are not phylogenetically structured in Tropidurinae. We found no correlation between metabolism, precipitation, and microhabitat usage. Species from warmer habitats had lower RMR compared to those from cooler habitats, supporting a mechanism of negative compensation in metabolic responses to temperature. Ectotherms from warmer habitats can limit energetic demand and expenditure through reduced RMR, whereas those from cooler habitats may sustain activity despite thermal constraints via increased RMR. Our work highlights the role of temperature in shaping metabolic responses in lizards, giving additional support to the notion that physiology and ecological contexts are intertwined.
    MeSH term(s) Animals ; Lizards/physiology ; Basal Metabolism ; Temperature ; Ecosystem ; Climate
    Language English
    Publishing date 2022-09-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1474896-4
    ISSN 2471-5646 ; 1932-5223 ; 2471-5646 ; 1932-5231 ; 1552-499X
    ISSN (online) 2471-5646 ; 1932-5223
    ISSN 2471-5646 ; 1932-5231 ; 1552-499X
    DOI 10.1002/jez.2656
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