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  1. Article ; Online: Nontyphoidal Salmonellosis Leading to Fatal Outcome in an Allogeneic Hematopoietic Stem Cell Transplant Recipient From Northeastern Brazil.

    Costa, Bruno Almeida / Duarte, Fernando Barroso / Duarte, João Vitor Araújo / Duarte, Isabella Araújo / Barroso, Karine Sampaio Nunes / Gonçalves, Alexia Triandopolis

    Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation

    2023  Volume 21, Issue 5, Page(s) 477–480

    MeSH term(s) Humans ; Brazil/epidemiology ; Salmonella Infections/diagnosis ; Graft vs Host Disease ; Hematopoietic Stem Cell Transplantation/adverse effects
    Language English
    Publishing date 2023-04-19
    Publishing country Turkey
    Document type Letter
    ZDB-ID 2396778-X
    ISSN 2146-8427 ; 1304-0855
    ISSN (online) 2146-8427
    ISSN 1304-0855
    DOI 10.6002/ect.2022.0317
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6632: Show issues Location:
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  2. Article ; Online: Obliterans With Organizing Pneumonia: A Possible Misdiagnosis of Lung Graft-Versus-Host Disease in Posttransplant Patients With COVID-19.

    Duarte, Fernando Barroso / Lemes, Romélia Pinheiro Gonçalves / Barroso, Karine Sampaio Nunes / Vasconcelos, João Paulo / Pitombeira, Beatriz Stela Gomes de Souza / Gurgel, Lívia Andrade / Viana, Thaísa Marjore Menezes / Duarte, Beatrice Araújo / Duarte, Isabella Araujo / Moura, Anna Thawanny Gadelha

    Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation

    2021  Volume 19, Issue 4, Page(s) 393–395

    MeSH term(s) Aged ; COVID-19/complications ; COVID-19/diagnosis ; COVID-19/virology ; COVID-19 Serological Testing ; Cryptogenic Organizing Pneumonia/diagnosis ; Cryptogenic Organizing Pneumonia/virology ; Diagnostic Errors ; Graft vs Host Disease/diagnosis ; Graft vs Host Disease/etiology ; Hematopoietic Stem Cell Transplantation/adverse effects ; Humans ; Male ; Myelodysplastic Syndromes/diagnosis ; Myelodysplastic Syndromes/surgery ; Predictive Value of Tests ; Tomography, X-Ray Computed ; Transplantation, Homologous ; Treatment Outcome
    Language English
    Publishing date 2021-02-01
    Publishing country Turkey
    Document type Case Reports ; Letter
    ZDB-ID 2396778-X
    ISSN 2146-8427 ; 1304-0855
    ISSN (online) 2146-8427
    ISSN 1304-0855
    DOI 10.6002/ect.2020.0360
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6632: Show issues Location:
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  3. Article ; Online: Wernicke's encephalopathy in a patient with non-Hodgkin's lymphoma post-Autologous HSCT.

    Leitão, João Paulo de Vasconcelos / Lemes, Romélia Pinheiro Gonçalves / Barbosa, Maritza Cavalcante / Araújo, Beatriz Stela Gomes de Souza Pitombeira / Barroso, Karine Sampaio Nunes / Kaufman, Jacques / Santos, Talyta Ellen de Jesus Dos / Moura, Anna Thawanny Gadelha / Barreto, André Rodrigues Façanha / Duarte, Fernando Barroso

    Revista da Associacao Medica Brasileira (1992)

    2018  Volume 64, Issue 10, Page(s) 882–884

    Abstract: Wernick's Encephalopathy (WE) is an acute neuropsychiatric syndrome caused by thiamine deficiency post hematopoietic stem cell transplant (HSCT). WE is associated with high mortality and morbidity rates, but due to its rare occurrence, it is rarely ... ...

    Abstract Wernick's Encephalopathy (WE) is an acute neuropsychiatric syndrome caused by thiamine deficiency post hematopoietic stem cell transplant (HSCT). WE is associated with high mortality and morbidity rates, but due to its rare occurrence, it is rarely considered in patients submitted to this procedure. Considering that, the manuscript reports the clinical characteristics and the possible factors that predisposed the occurrence of WE in a patient with non-Hodgkin's lymphoma post-Autologous HSCT. We conclude that WE should be considered in patients submitted to autologous HSCT associated with prolonged use of TPN and malnutrition.
    MeSH term(s) Adult ; Female ; Hematopoietic Stem Cell Transplantation/adverse effects ; Humans ; Lymphoma, Non-Hodgkin/therapy ; Risk Factors ; Thiamine Deficiency/complications ; Transplantation, Autologous ; Wernicke Encephalopathy/diagnostic imaging ; Wernicke Encephalopathy/etiology
    Language English
    Publishing date 2018-12-03
    Publishing country Brazil
    Document type Case Reports ; Journal Article
    ZDB-ID 2027973-5
    ISSN 1806-9282 ; 0104-4230
    ISSN (online) 1806-9282
    ISSN 0104-4230
    DOI 10.1590/1806-9282.64.10.882
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Successful hematopoietic stem cell mobilization with vinorelbine and filgrastim in germ cell tumor.

    Carneiro-Silva, Fabiana Aguiar / Brunetta, Denise Menezes / Kaufman, Jacques / Leitão, João Paulo Vasconcelos / Barroso, Karine Sampaio Nunes / Barbosa, Suzanna Araújo Tavares / Carlos, Luciana Maria de Barros / Barroso-Duarte, Fernando

    Clinical and experimental medicine

    2017  Volume 17, Issue 3, Page(s) 417–418

    Abstract: Germ cell tumor (GCT) is the most frequent cancer in young men and is highly curable. Almost 80 % of patients with the disease in an advanced stage achieve a reliable response to cisplatin combination chemotherapy. For relapsing or refractory disease, ... ...

    Abstract Germ cell tumor (GCT) is the most frequent cancer in young men and is highly curable. Almost 80 % of patients with the disease in an advanced stage achieve a reliable response to cisplatin combination chemotherapy. For relapsing or refractory disease, autologous hematopoietic stem cell transplantation (HSCT) is an effective therapy. The two most used mobilization strategies for HSC collection are filgrastim alone or filgrastim after chemotherapy (chemomobilization). HSC collection with filgrastim mobilization can be difficult, especially in highly treated patients. While the addition of chemotherapy improves mobilization and reduces the number of apheresis sessions, it can increase morbidity rate as well. We describe a case of a 45-year-old male with classical seminoma who was submitted to orchiectomy. Two months after, he presented progression of the tumor. He received four cycles of cisplatin, etoposide and bleomycin, with residual retroperitoneal mass and cervical lymphadenopathy. Further, he was submitted to three more cycles of cisplatin, ifosfamide and paclitaxel. Thereupon, he showed partial response. At that moment, autologous HSC transplantation was considered. In the first mobilization, filgrastim alone was used without success in harvesting. The second mobilization consisted of vinorelbine at day 1 (35 mg/m
    Language English
    Publishing date 2017-08
    Publishing country Italy
    Document type Letter
    ZDB-ID 2053018-3
    ISSN 1591-9528 ; 1591-8890
    ISSN (online) 1591-9528
    ISSN 1591-8890
    DOI 10.1007/s10238-016-0425-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5481: Show issues Location:
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  5. Article ; Online: Hodgkin's Lymphoma - evaluation of patients submitted to Autologous transplantation of hematopoietic cells in the Hematology Service of the Hospital Walter Cantídio - Fortaleza, Brazil.

    Duarte, Fernando Barroso / Fernandes, Mabel Gomes de Brito / Kaufmann, Jacques / Barroso, Karine Sampaio Nunes / Leitão, João Paulo de Vasconcelos / Araujo, Beatriz Stela Gomes de Souza Pitombeira / Costa, Clara Maria Bastos Eloy da / Quixadá-Medica, Acy Teles / Holanda, Jacqueline de Souza / Landim, Samuel Vasconcelos / Pitombeira, Maria Helena

    Revista da Associacao Medica Brasileira (1992)

    2016  Volume 62 Suppl 1, Page(s) 34–38

    Abstract: The Autologous HSCT is an important alternative for refractory or recurrent HL patients in terms of survival and improved quality of life. This study analyzes the results of autologous BMT performed in HL patients in the Transplant Unit of the HUWC/ ... ...

    Abstract The Autologous HSCT is an important alternative for refractory or recurrent HL patients in terms of survival and improved quality of life. This study analyzes the results of autologous BMT performed in HL patients in the Transplant Unit of the HUWC/ HEMOCE (Fortaleza - CE, Brazil). Fifty-two transplanted patients were studied from January 2009 to October 2015, among them, 30 men and 22 women, mean age of 28.2 years. All of them received GCS-F during the mobilization, in some cases associated with Vinorelbine or Plerixafor, with CD34 collection averaging 4.8 CD34/kg. The conditioning was performed with BEAC, NEAM or BEAM and the grafting with an average of 10 days. The evaluation on D + 100 showed: CR - 42 (82.7%), PR - 08 (13.5%) and 02 (3.8%) deaths, three and six days after cell infusion. After the D+100, 08 patients in CR showed HL recurrence from 06 to 36 months; 03 died and 05 are being treated with brentuximab; among the 08 patients in PR, 01 died due to HL activity, 04 months after BMT and 07 patients are undergoing treatment. The final evaluation of HL transplant patients showed an OS of 88.5% and a DFS of 61.5% in 6 years, with OS of the chemosensitive patients of 81% and of the chemoresistant ones, of 72.6%. It is possible to conclude that the Autologous HSCT has shown to be an excellent rescue therapy regarding tolerance, as well as the overall survival.
    MeSH term(s) Adolescent ; Adult ; Brazil ; Disease-Free Survival ; Female ; Hematopoietic Stem Cell Transplantation/methods ; Hematopoietic Stem Cell Transplantation/mortality ; Hodgkin Disease/mortality ; Hodgkin Disease/surgery ; Humans ; Male ; Middle Aged ; Time Factors ; Transplantation Conditioning/methods ; Transplantation, Autologous/methods ; Treatment Outcome ; Young Adult
    Language English
    Publishing date 2016-10
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 2027973-5
    ISSN 1806-9282 ; 0104-4230
    ISSN (online) 1806-9282
    ISSN 0104-4230
    DOI 10.1590/1806-9282.62.suppl1.34
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Association of oxidative stress and DNA damage with grafting time in patients with multiple myeloma and lymphoma submitted to autologous hematopoietic stem cell transplantation.

    Santos, Thayna Nogueira Dos / Duarte, Fernando Barroso / Maia Filho, Pedro Aurio / Santos, Talyta Ellen de Jesus Dos / Barbosa, Maritza Cavalcante / Almeida Filho, Tarcísio Paulo de / Cavalcanti, Bruno Coelho / Vasconcelos, Paulo Roberto Leitão de / Dutra, Luana Leticia / Lopes, Germison Silva / Costa, Franciclea Oliveira / Leitão, João Paulo Vasconcelos / KauFman, Jacques / AraúJo, Beatriz Stella Pitombeira / Barroso, Karine Sampaio Nunes / Lemes, Romélia Pinheiro Gonçalves

    Revista da Associacao Medica Brasileira (1992)

    2016  Volume 62 Suppl 1, Page(s) 39–43

    Abstract: The aim of the study was to investigate the association between oxidative stress and DNA damage with grafting time in patients submitted to autologous hematopoietic stem-cell transplantation (HSCT). The study included 37 patients submitted to autologous ... ...

    Abstract The aim of the study was to investigate the association between oxidative stress and DNA damage with grafting time in patients submitted to autologous hematopoietic stem-cell transplantation (HSCT). The study included 37 patients submitted to autologous HSCT diagnosed with Multiple Myeloma (MM) and lymphoma (Hodgkin's and non-Hodgkin's). Biomarkers of oxidative stress and DNA damage index (DI) were performed at baseline (pre-CR) of the disease and during the conditioning regimen (CR), one day after the HSCT, ten days after HSCT and twenty days after HSCT, as well as in the control group consisting of 30 healthy individuals. The outcomes showed that both groups of patients had an hyperoxidative state with high DI when compared to baseline and to the control group and that the CR exacerbated this condition. However, after the follow-up period of the study, this picture was re-established to the baseline levels of each pathology. The study patients with MM showed a mean grafting time of 10.75 days (8 to 13 days), with 10.15 days (8 to 15 days) for the lymphoma patients. In patients with MM, there was a negative correlation between the grafting time and the basal levels of GPx (r = -0.54; p = 0.034), indicating that lower levels of this important enzyme are associated with a longer grafting time. For the DI, the correlation was a positive one (r = 0.529; p = 0.030). In the group with lymphoma, it was observed that the basal levels of NOx were positively correlated with grafting time (r = 0.4664, p = 0.032). The data indicate the potential of these biomarkers as predictors of toxicity and grafting time in patients with MM and Lymphomas submitted to autologous HSCT.
    MeSH term(s) Analysis of Variance ; Biomarkers ; Case-Control Studies ; DNA Damage/physiology ; Female ; Hematopoietic Stem Cell Transplantation/methods ; Humans ; Lymphoma/genetics ; Lymphoma/metabolism ; Lymphoma/surgery ; Male ; Malondialdehyde/analysis ; Multiple Myeloma/genetics ; Multiple Myeloma/metabolism ; Multiple Myeloma/surgery ; Oxidative Stress/physiology ; Reference Values ; Time Factors ; Transplantation, Autologous/methods ; Treatment Outcome
    Chemical Substances Biomarkers ; Malondialdehyde (4Y8F71G49Q)
    Language English
    Publishing date 2016-10
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 2027973-5
    ISSN 1806-9282 ; 0104-4230
    ISSN (online) 1806-9282
    ISSN 0104-4230
    DOI 10.1590/1806-9282.62.suppl1.39
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Brazilian Nutritional Consensus in Hematopoietic Stem Cell Transplantation: Adults.

    Barban, Juliana Bernardo / Simões, Belinda Pinto / Moraes, Bruna Del Guerra de Carvalho / Anunciação, Cássia Rehem da / Rocha, Cristiane Santos da / Pintor, Daniela Cristina Querino / Guerra, Daiane Cristina / Silva, Deise Andrade / Brandão, Edith de Castro Martins / Kerbauy, Fábio / Pires, Fernanda Ramos de Oliveira / Morais, Graciele Lima / Schmidt Filho, Jayr / Sicchieri, Juliana Maria Faccioli / Barroso, Karine Sampaio Nunes / Viana, Luciana Verçoza / Rocha, Mariana Hollanda Martins da / Guimarães, Maysa Penteado / Lazzari, Natalia Leonetti Couto /
    Hamerschlak, Nelson / Ramos, Patricia / Gomes, Plinio Nascimento / Mendonça, Priscila da Silva / Oliveira, Raquel Candido de / Scomparim, Renata Corrêa / Chiattone, Ricardo / Diez-Garcia, Rosa Wanda / Cardenas, Thaís de Campos / Miola, Thais Manfrinato / Costa, Thalita Cristina de Mello / Rocha, Vanderson / Pereira, Andrea Z

    Einstein (Sao Paulo, Brazil)

    2020  Volume 18, Page(s) AE4530

    Abstract: The nutritional status of patients submitted to hematopoietic stem cell transplant is considered an independent risk factor, which may influence on quality of life and tolerance to the proposed treatment. The impairment of nutritional status during ... ...

    Abstract The nutritional status of patients submitted to hematopoietic stem cell transplant is considered an independent risk factor, which may influence on quality of life and tolerance to the proposed treatment. The impairment of nutritional status during hematopoietic stem cell transplant occurs mainly due to the adverse effects resulting from conditioning to which the patient is subjected. Therefore, adequate nutritional evaluation and follow-up during hematopoietic stem cell transplant are essential. To emphasize the importance of nutritional status and body composition during treatment, as well as the main characteristics related to the nutritional assessment of the patient, the Brazilian Consensus on Nutrition in Hematopoietic Stem Cell Transplant: Adults was prepared, aiming to standardize and update Nutritional Therapy in this area. Dietitians, nutrition physicians and hematologists from 15 Brazilian centers thar are references in hematopoietic stem cell transplant took part.
    MeSH term(s) Adult ; Anthropometry ; Brazil ; Hematopoietic Stem Cell Transplantation/adverse effects ; Hematopoietic Stem Cell Transplantation/standards ; Humans ; Nutrition Assessment ; Nutrition Therapy/methods ; Nutrition Therapy/standards ; Nutritional Status ; Parenteral Nutrition/methods ; Parenteral Nutrition/standards ; Transplantation Conditioning
    Language Portuguese
    Publishing date 2020-02-07
    Publishing country Brazil
    Document type Consensus Development Conference ; Journal Article
    ZDB-ID 2418293-X
    ISSN 2317-6385 ; 2317-6385
    ISSN (online) 2317-6385
    ISSN 2317-6385
    DOI 10.31744/einstein_journal/2020AE4530
    Database MEDical Literature Analysis and Retrieval System OnLINE

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