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  1. Article ; Online: Comments on Case Report: A fatal case of

    Barrs, Vanessa R

    Access microbiology

    2023  Volume 5, Issue 4

    Language English
    Publishing date 2023-04-03
    Publishing country England
    Document type Journal Article
    ISSN 2516-8290
    ISSN (online) 2516-8290
    DOI 10.1099/acmi.0.000561.v3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Salmonella enterica

    Wilson, Remon / Barrs, Vanessa R

    JFMS open reports

    2024  Volume 10, Issue 1, Page(s) 20551169231221951

    Abstract: Case summary: A 2-year-old male neutered domestic shorthair cat presented with an acute onset of muscular pain, ataxia and fever. Serological tests for : Relevance and novel information: Infection ... ...

    Abstract Case summary: A 2-year-old male neutered domestic shorthair cat presented with an acute onset of muscular pain, ataxia and fever. Serological tests for
    Relevance and novel information: Infection with
    Language English
    Publishing date 2024-01-31
    Publishing country England
    Document type Case Reports
    ZDB-ID 2822177-1
    ISSN 2055-1169 ; 2055-1169
    ISSN (online) 2055-1169
    ISSN 2055-1169
    DOI 10.1177/20551169231221951
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  3. Article ; Online: Feline Panleukopenia: A Re-emergent Disease.

    Barrs, Vanessa R

    The Veterinary clinics of North America. Small animal practice

    2019  Volume 49, Issue 4, Page(s) 651–670

    Abstract: Feline panleukopenia (FPL) is caused by a Carnivore protoparvovirus infection. Feline parvovirus (FPV) causes most cases. When Canine parvovirus 2 (CPV-2) first emerged, it could not replicate in cats. All current CPV variants (CPV-2a-c) can infect cats ... ...

    Abstract Feline panleukopenia (FPL) is caused by a Carnivore protoparvovirus infection. Feline parvovirus (FPV) causes most cases. When Canine parvovirus 2 (CPV-2) first emerged, it could not replicate in cats. All current CPV variants (CPV-2a-c) can infect cats to cause subclinical disease or FPL. Feline panleukopenia has re-emerged in Australia in shelter cats associated with failure to vaccinate. Parvoviruses can remain latent in mononuclear cells post-infection. Molecular methods such as polymerase chain reaction are used to determine the infecting strain. Current perspectives on causes, epidemiology, diagnosis, treatment, prognostic indicators, and management of outbreaks in shelters are reviewed.
    MeSH term(s) Animals ; Cats ; Communicable Diseases, Emerging/transmission ; Communicable Diseases, Emerging/veterinary ; Communicable Diseases, Emerging/virology ; Feline Panleukopenia/epidemiology ; Feline Panleukopenia/pathology ; Feline Panleukopenia/virology ; Parvoviridae Infections/epidemiology ; Parvoviridae Infections/veterinary ; Parvoviridae Infections/virology ; Parvovirus, Canine
    Language English
    Publishing date 2019-04-06
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 757662-6
    ISSN 1878-1306 ; 0195-5616
    ISSN (online) 1878-1306
    ISSN 0195-5616
    DOI 10.1016/j.cvsm.2019.02.006
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  4. Article: Dermatological Problems of Brachycephalic Dogs.

    Hobi, Stefan / Barrs, Vanessa R / Bęczkowski, Paweł M

    Animals : an open access journal from MDPI

    2023  Volume 13, Issue 12

    Abstract: Brachycephalic dogs are not only affected by brachycephalic obstructive airway syndrome (BOAS), but are also frequently referred to veterinary dermatologists for skin conditions, with English bulldogs and pugs particularly over-represented. Some skin ... ...

    Abstract Brachycephalic dogs are not only affected by brachycephalic obstructive airway syndrome (BOAS), but are also frequently referred to veterinary dermatologists for skin conditions, with English bulldogs and pugs particularly over-represented. Some skin diseases, such as skin fold dermatitis, are directly associated with the abnormal anatomic conformation of brachycephalic dogs, while for others, such as atopic dermatitis and viral pigmented plaques, there is an underlying genetic basis or a general predisposition. Anatomic alterations associated with brachycephaly, leading to fold formation of the skin and stenosis of the ear canal, together with primary immunodeficiencies described in some breeds, favor the development of pyoderma,
    Language English
    Publishing date 2023-06-16
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani13122016
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  5. Article ; Online: Dermatological Problems of Brachycephalic Dogs

    Hobi, Stefan / Barrs, Vanessa R. / Bęczkowski, Paweł M.

    Animals. 2023 June 16, v. 13, no. 12

    2023  

    Abstract: Brachycephalic dogs are not only affected by brachycephalic obstructive airway syndrome (BOAS), but are also frequently referred to veterinary dermatologists for skin conditions, with English bulldogs and pugs particularly over-represented. Some skin ... ...

    Abstract Brachycephalic dogs are not only affected by brachycephalic obstructive airway syndrome (BOAS), but are also frequently referred to veterinary dermatologists for skin conditions, with English bulldogs and pugs particularly over-represented. Some skin diseases, such as skin fold dermatitis, are directly associated with the abnormal anatomic conformation of brachycephalic dogs, while for others, such as atopic dermatitis and viral pigmented plaques, there is an underlying genetic basis or a general predisposition. Anatomic alterations associated with brachycephaly, leading to fold formation of the skin and stenosis of the ear canal, together with primary immunodeficiencies described in some breeds, favor the development of pyoderma, Malassezia dermatitis, and otitis externa/media. In addition, the frequently neglected but often lifelong dermatological problems of brachycephalic dogs are an important consideration when discussing genetic and medical conditions affecting the welfare of those dogs. Here we review the current state of knowledge concerning dermatological problems in brachycephalic dogs and combine it with clinical experience in the management of these challenging disorders.
    Keywords Malassezia ; atopic dermatitis ; ear canal ; immunosuppression ; otitis externa ; pyoderma
    Language English
    Dates of publication 2023-0616
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article ; Online
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani13122016
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  6. Article ; Online: Invasive fungal infections and oomycoses in cats 2. Antifungal therapy.

    Barrs, Vanessa R / Hobi, Stefan / Wong, Angeline / Sandy, Jeanine / Shubitz, Lisa F / Bęczkowski, Paweł M

    Journal of feline medicine and surgery

    2024  Volume 26, Issue 1, Page(s) 1098612X231220047

    Abstract: Clinical relevance: Invasive fungal infections (IFIs) and oomycoses (hereafter termed invasive fungal-like infections [IFLIs]) are characterised by penetration of tissues by fungal elements. The environment is the most common reservoir of infection. ... ...

    Abstract Clinical relevance: Invasive fungal infections (IFIs) and oomycoses (hereafter termed invasive fungal-like infections [IFLIs]) are characterised by penetration of tissues by fungal elements. The environment is the most common reservoir of infection. IFIs and IFLIs can be frustrating to treat because long treatment times are usually required and, even after attaining clinical cure, there may be a risk of relapse. Owner compliance with medication administration and recheck examinations can also decline over time. In addition, some antifungal drugs are expensive, have variable interpatient pharmacokinetic properties, can only be administered parenterally and/or have common adverse effects (AEs). Despite these limitations, treatment can be very rewarding, especially when an otherwise progressive and fatal disease is cured.
    Aim: In the second of a two-part article series, the spectrum of activity, mechanisms of action, pharmacokinetic and pharmacodynamic properties, and AEs of antifungal drugs are reviewed, and the treatment and prognosis of specific IFIs/IFLIs - dermatophytic pseudomycetoma, cryptococcosis, sino-orbital aspergillosis, coccidioidomycosis, histoplasmosis, sporotrichosis, phaeohyphomycosis, mucormycosis and oomycosis - are discussed. Part 1 reviewed the diagnostic approach to IFIs and IFLIs.
    Evidence base: Information on antifungal drugs is drawn from pharmacokinetic studies in cats. Where such studies have not been performed, data from 'preclinical' animals (non-human studies) and human studies are reviewed. The review also draws on the wider published evidence and the authors' combined expertise in feline medicine, mycology, dermatology, clinical pathology and anatomical pathology.
    Abbreviations for antifungal drugs: AMB (amphotericin B); FC (flucytosine); FCZ (fluconazole); ISA (isavuconazole); ITZ (itraconazole); KCZ (ketoconazole); PCZ (posaconazole); TRB (terbinafine); VCZ (voriconazole).
    MeSH term(s) Cats ; Animals ; Antifungal Agents/therapeutic use ; Invasive Fungal Infections/veterinary ; Itraconazole ; Terbinafine ; Coccidioidomycosis/veterinary ; Cat Diseases/drug therapy
    Chemical Substances Antifungal Agents ; Itraconazole (304NUG5GF4) ; Terbinafine (G7RIW8S0XP)
    Language English
    Publishing date 2024-01-08
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2049047-1
    ISSN 1532-2750 ; 1098-612X
    ISSN (online) 1532-2750
    ISSN 1098-612X
    DOI 10.1177/1098612X231220047
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  7. Article ; Online: Malassezia dermatitis in dogs and cats.

    Hobi, Stefan / Bęczkowski, Paweł M / Mueller, Ralf / Tse, May / Barrs, Vanessa R

    Veterinary journal (London, England : 1997)

    2024  Volume 304, Page(s) 106084

    Abstract: Malassezia are members of the mycobiome of dogs and cats. In the presence of an underlying disease, these yeasts can proliferate, attach to the skin or mucosa to induce a secondary Malassezia dermatitis, otitis externa or paronychia. Since allergic ... ...

    Abstract Malassezia are members of the mycobiome of dogs and cats. In the presence of an underlying disease, these yeasts can proliferate, attach to the skin or mucosa to induce a secondary Malassezia dermatitis, otitis externa or paronychia. Since allergic dermatitis is one of the most common underlying causes, diagnostic investigation for allergy is often indicated. Cats may suffer from various other underlying problems, especially where Malassezia dermatitis is generalised. Malassezia dermatitis in dogs and cats is chronic, relapsing and pruritic. Direct cytology from dermatological lesions and the ear canal, showing "peanut-shaped" budding yeasts, facilitates a rapid and reliable diagnosis. Topical treatment includes antiseptic and antifungal azole-based products. Systemic treatment with oral antifungals is indicated only in severe or refractory disease. Identification and treatment of the underlying cause is essential for an optimal response. In this evidence-based narrative review, we discuss the clinical presentation of Malassezia dermatitis in dogs and cats, underlying comorbidities, and diagnostic considerations. Treatment is discussed in light of emerging evidence of antifungal resistance and the authors' clinical experience.
    MeSH term(s) Animals ; Cats ; Dogs ; Malassezia ; Dermatomycoses/diagnosis ; Dermatomycoses/drug therapy ; Dermatomycoses/veterinary ; Cat Diseases/diagnosis ; Cat Diseases/drug therapy ; Cat Diseases/microbiology ; Antifungal Agents/therapeutic use ; Dog Diseases/diagnosis ; Dog Diseases/drug therapy ; Dog Diseases/microbiology ; Neoplasm Recurrence, Local/veterinary ; Dermatitis/drug therapy ; Dermatitis/veterinary
    Chemical Substances Antifungal Agents
    Language English
    Publishing date 2024-02-29
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 428614-5
    ISSN 1532-2971 ; 0372-5545 ; 1090-0233
    ISSN (online) 1532-2971
    ISSN 0372-5545 ; 1090-0233
    DOI 10.1016/j.tvjl.2024.106084
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 552: Show issues Location:
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  8. Article ; Online: Prevalence of Babesia and Ehrlichia in owned dogs with suspected tick-borne infection in Hong Kong, and risk factors associated with Babesia gibsoni

    Muguiro, Daniela Hernandez / Nekouei, Omid / Lee, Kei Ying / Hill, Fraser / Barrs, Vanessa R.

    Preventive Veterinary Medicine. 2023 May, v. 214 p.105908-

    2023  

    Abstract: Babesiosis and ehrlichiosis are the most clinically significant tick-borne infections in dogs. Although epidemiological investigations of these diseases have been performed in some Asian regions, little data is available in Hong Kong, where competent ... ...

    Abstract Babesiosis and ehrlichiosis are the most clinically significant tick-borne infections in dogs. Although epidemiological investigations of these diseases have been performed in some Asian regions, little data is available in Hong Kong, where competent vector tick species are endemic. The objectives of this study were to determine the molecular prevalence of Ehrlichia canis and Babesia species (B. canis, B. gibsoni, B. vogeli) in owned dogs suspected of tick-borne infection in Hong Kong and to identify risk factors associated with B. gibsoni infection. Electronic records from the Veterinary Diagnostic Laboratory of City University of Hong Kong were searched to identify canine blood samples submitted for molecular testing of these pathogens by real time PCR between March 2018 and May 2021. Electronic patient records from the affiliated veterinary hospital were searched to identify a subset of tested dogs to investigate the potential risk factors for B. gibsoni infection using logistic regression models. Among 1508 tested dogs for all four pathogens of interest, Babesia spp. were detected in 435 (28.8%) and E. canis in 112 (7.4%). Babesia gibsoni was detected in 408 dogs while B. vogeli was detected in 27 dogs. Babesia canis was not detected in any dog. Co-infections of different combinations of B. gibsoni, B. vogeli and E. canis were present in 25 dogs. In multivariable logistic regression, mixed breed dogs were more likely to be infected with B. gibsoni than purebreds (P = 0.005), while dogs > 10 years of age were less likely to be infected than younger dogs (P = 0.019). Hematological abnormalities significantly associated with B. gibsoni infection included thrombocytopenia, neutropenia, or pancytopenia. Babesiosis caused by B. gibsoni is a common infection in owned dogs suspected of tick-borne infection in Hong Kong. The risk factors reported should be considered in diagnosing dogs suspected of infection with this agent. Furthermore, consideration for testing for B. gibsoni infection should be given if the results of a complete blood count show thrombocytopenia even in the absence of anemia, neutropenia or pancytopenia.
    Keywords Babesia canis ; Babesia gibsoni ; Ehrlichia canis ; anemia ; babesiosis ; blood ; dogs ; ehrlichiosis ; neutropenia ; patients ; purebreds ; quantitative polymerase chain reaction ; regression analysis ; risk ; thrombocytopenia ; ticks ; veterinary clinics ; China ; Babesia ; Ehrlichia ; Tick-borne infection ; Prevalence ; Canine
    Language English
    Dates of publication 2023-05
    Publishing place Elsevier B.V.
    Document type Article ; Online
    Note Use and reproduction
    ZDB-ID 43399-8
    ISSN 1873-1716 ; 0167-5877
    ISSN (online) 1873-1716
    ISSN 0167-5877
    DOI 10.1016/j.prevetmed.2023.105908
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    In stock of ZB MED Bonn / Germany

    Z 5367: Show issues

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  9. Article: Babesia gibsoni

    Almendros, Angel / Choi, Y R / Bęczkowski, Paweł M / Baiker, Kerstin / Barrs, Vanessa R / Beatty, Julia A

    Animals : an open access journal from MDPI

    2023  Volume 13, Issue 13

    Abstract: Tick-borne ... ...

    Abstract Tick-borne haemoparasite
    Language English
    Publishing date 2023-06-27
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani13132128
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  10. Article: Corrigendum to 'Rhinitis due to

    Langlois, Isabelle / Barrs, Vanessa R / Dufresne, Philippe J

    Medical mycology case reports

    2021  Volume 33, Page(s) 38

    Abstract: This corrects the article DOI: 10.1016/j.mmcr.2020.11.001.]. ...

    Abstract [This corrects the article DOI: 10.1016/j.mmcr.2020.11.001.].
    Language English
    Publishing date 2021-07-08
    Publishing country Netherlands
    Document type Published Erratum
    ZDB-ID 2670415-8
    ISSN 2211-7539
    ISSN 2211-7539
    DOI 10.1016/j.mmcr.2021.06.004
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