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Article ; Online: Donor-site local anaesthetic infusion catheter as an opioid-sparing agent in free flap reconstruction of the head and neck: a valuable adjunct to an enhanced recovery protocol.

Henry, C J / Barry, C P

The British journal of oral & maxillofacial surgery

2021 Volume 60, Issue 2, Page(s) 196–198

Abstract: This paper presents the results of a retrospective case-controlled cohort study to investigate the effectiveness of a donor-site local anaesthetic infusion protocol to reduce opioid requirements, length of intensive therapy unit (ITU) stay, and incidence ...

Abstract	This paper presents the results of a retrospective case-controlled cohort study to investigate the effectiveness of a donor-site local anaesthetic infusion protocol to reduce opioid requirements, length of intensive therapy unit (ITU) stay, and incidence of postoperative delirium. Adult free flap head and neck patients were identified from a prospective database (n = 86). There was a significant reduction in mean opioid requirements (p < 0.001). Postoperative delirium was observed in 12 of 35 patients before introduction of the protocol, and in 10 of 51 patients after its introduction (p = 0.139). Donor-site local anaesthetic infusion reduces opioid requirements for patients undergoing head and neck free flap reconstruction, and is a valuable adjunct to an enhanced recovery protocol.
MeSH term(s)	Analgesics, Opioid/therapeutic use ; Anesthetics, Local ; Catheters ; Cohort Studies ; Delirium/drug therapy ; Free Tissue Flaps ; Humans ; Pain, Postoperative/drug therapy ; Retrospective Studies
Chemical Substances	Analgesics, Opioid ; Anesthetics, Local
Language	English
Publishing date	2021-01-22
Publishing country	Scotland
Document type	Journal Article
ZDB-ID	605685-4
ISSN	1532-1940 ; 0266-4356
ISSN (online)	1532-1940
ISSN	0266-4356
DOI	10.1016/j.bjoms.2020.11.026
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Article: Recurrent Ameloblastoma Involving Fibula Neo-mandible: Management with Digital Planning and Reconstruction Using a Contralateral Free Fibula Flap.

Beecher, Suzanne M / Lennon, Paul / O'Shaughnessy, Michael / Barry, Conor P

Cureus

2020 Volume 12, Issue 4, Page(s) e7880

Abstract: Ameloblastoma is a locally aggressive tumor that most commonly arises in the mandible. It has a high rate of recurrence if inadequately excised. We report a case of a patient who developed recurrence of his ameloblastoma in his fibula flap mandibular ... ...

Abstract	Ameloblastoma is a locally aggressive tumor that most commonly arises in the mandible. It has a high rate of recurrence if inadequately excised. We report a case of a patient who developed recurrence of his ameloblastoma in his fibula flap mandibular reconstruction despite clear resection margins 23 years after resection. This is the first reported case of recurrent ameloblastoma in a neo-mandible reconstruction in the setting of negative margins. We discuss its surgical management using digital planning and reconstruction using a contralateral free fibula flap. Ameloblastoma is a locally aggressive entity that requires complete excision. Recurrence can even occur in the reconstruction, which can present a challenge to manage. Consideration should be given to repeat excision and second osseous flap reconstruction.
Language	English
Publishing date	2020-04-29
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.7880
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Article ; Online: Overnight endotracheal intubation in patients who have free-flap reconstruction of the head and neck: a cautionary note.

Henry, C J / Halligan, M / Bozic, A / Barry, C P

The British journal of oral & maxillofacial surgery

2019 Volume 57, Issue 8, Page(s) 796–797

MeSH term(s)	Free Tissue Flaps ; Head and Neck Neoplasms/surgery ; Humans ; Intubation, Intratracheal ; Reconstructive Surgical Procedures ; Retrospective Studies
Language	English
Publishing date	2019-06-27
Publishing country	Scotland
Document type	Journal Article
ZDB-ID	605685-4
ISSN	1532-1940 ; 0266-4356
ISSN (online)	1532-1940
ISSN	0266-4356
DOI	10.1016/j.bjoms.2019.06.011
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Article ; Online: Perioperative primary herpetic stomatitis of an intraoral skin paddle that mimicked compromise of the free flap.

McGoldrick, D M / Barry, C P

The British journal of oral & maxillofacial surgery

2017 Volume 55, Issue 9, Page(s) 986

MeSH term(s)	Aged ; Carcinoma, Squamous Cell/surgery ; Diagnosis, Differential ; Free Tissue Flaps ; Glossectomy ; Humans ; Male ; Mouth Neoplasms/surgery ; Scapula/transplantation ; Stomatitis, Herpetic/diagnosis ; Stomatitis, Herpetic/virology ; Surgical Wound Infection/diagnosis ; Surgical Wound Infection/virology
Language	English
Publishing date	2017
Publishing country	Scotland
Document type	Case Reports ; Letter
ZDB-ID	605685-4
ISSN	1532-1940 ; 0266-4356
ISSN (online)	1532-1940
ISSN	0266-4356
DOI	10.1016/j.bjoms.2017.09.008
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Article ; Online: Tailored approach to oromandibular reconstruction in patients with compromised lower limb vessels.

Barry, Conor P / Brown, James / Hanlon, Rebecca / Shaw, Richard

Head & neck

2017 Volume 39, Issue 5, Page(s) 916–920

Abstract: Background: The purpose of this study was to compare outcomes for segmental reconstruction of the mandible between patients who underwent reconstruction with a fibula flap (group 1), and those with an alternative osseous free flap in which the fibula ... ...

Abstract	Background: The purpose of this study was to compare outcomes for segmental reconstruction of the mandible between patients who underwent reconstruction with a fibula flap (group 1), and those with an alternative osseous free flap in which the fibula flap was unsuitable either for defect reasons (group 2) or in which the fibula flap could not safely be harvested because of compromised leg vessels (group 3). Methods: One hundred fifty-two patients who underwent osseous free flap reconstruction of a mandibular segmental defect between January 2008 and June 2014 were identified from operating records. Outcomes between groups was compared. Results: The flap success rate was 97% and the late recipient-site complication rate was 19%. There was no difference in flap success or complication rates between groups. Conclusion: Bony reconstruction of the mandible can be achieved with no compromise in flap success even where preoperative vascular studies or the nature of the defect deem the fibula unsuitable. © 2017 Wiley Periodicals, Inc. Head Neck 39: 916-920, 2017.
Language	English
Publishing date	2017-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	645165-2
ISSN	1097-0347 ; 0148-6403 ; 1043-3074
ISSN (online)	1097-0347
ISSN	0148-6403 ; 1043-3074
DOI	10.1002/hed.24709
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Article ; Online: Multi-omic characterisation of

Barry, Craig P / Gillane, Rosemary / Talbo, Gert H / Plan, Manual / Palfreyman, Robin / Haber-Stuk, Andrea K / Power, John / Nielsen, Lars K / Marcellin, Esteban

Molecular omics

2022 Volume 18, Issue 3, Page(s) 226–236

Abstract: The emergence of multidrug-resistant pathogenic bacteria creates a demand for novel antibiotics with distinct mechanisms of action. Advances in next-generation genome sequencing promised a paradigm shift in the quest to find new bioactive secondary ... ...

Abstract	The emergence of multidrug-resistant pathogenic bacteria creates a demand for novel antibiotics with distinct mechanisms of action. Advances in next-generation genome sequencing promised a paradigm shift in the quest to find new bioactive secondary metabolites. Genome mining has proven successful for predicting putative biosynthetic elements in secondary metabolite superproducers such as
MeSH term(s)	Genomics ; Multigene Family ; Secondary Metabolism/genetics ; Streptomyces/genetics ; Streptomyces/metabolism
Language	English
Publishing date	2022-03-28
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	2515-4184
ISSN (online)	2515-4184
DOI	10.1039/d1mo00150g
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Article ; Online: 'Out of house' virtual surgical planning for mandible reconstruction after cancer resection: is it oncologically safe?

Barry, C P / MacDhabheid, C / Tobin, K / Stassen, L F / Lennon, P / Toner, M / O'Regan, E / Clark, J R

International journal of oral and maxillofacial surgery

2020 Volume 50, Issue 8, Page(s) 999–1002

Abstract: The purpose of this study was to investigate whether the time delay between 'out of house' proprietary virtual surgical planning (OH-VSP) of the mandibular resection for oral cancer and the actual surgery results in compromised margins and oncological ... ...

Abstract	The purpose of this study was to investigate whether the time delay between 'out of house' proprietary virtual surgical planning (OH-VSP) of the mandibular resection for oral cancer and the actual surgery results in compromised margins and oncological disadvantage for the patient. Outcomes of patients who had OH-VSP of their mandibular resection and reconstruction were compared with those of patients who had the same surgery using a conventional non-VSP approach. The groups were similar in patient demographics, tumour stage and size, nodal status, and reconstruction complexity. VSP resulted in a significant reduction in operating time (P<0.01). VSP did not affect bony (P=0.49) or soft tissue (P=0.22) margin status. In summary, VSP reduced the operating theatre time, and despite the time interval between bony resection planning and surgery, there was no compromise to the oncological safety of the operation.
MeSH term(s)	Fibula ; Free Tissue Flaps ; Humans ; Mandible/surgery ; Mandibular Reconstruction ; Mouth Neoplasms/surgery ; Surgery, Computer-Assisted
Language	English
Publishing date	2020-12-13
Publishing country	Denmark
Document type	Journal Article
ZDB-ID	353721-3
ISSN	1399-0020 ; 0901-5027
ISSN (online)	1399-0020
ISSN	0901-5027
DOI	10.1016/j.ijom.2020.11.008
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Zs.A 931: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article: Superior border plating technique in the management of isolated mandibular angle fractures: a retrospective study of 50 consecutive patients.

Barry, Conor P / Kearns, Gerard J

Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons

2007 Volume 65, Issue 8, Page(s) 1544–1549

Abstract: Purpose: To determine the complication rate for patients presenting with isolated mandibular angle fractures treated by open reduction and internal fixation using a single superior border miniplate technique.: Patients and methods: This is a ... ...

Abstract	Purpose: To determine the complication rate for patients presenting with isolated mandibular angle fractures treated by open reduction and internal fixation using a single superior border miniplate technique. Patients and methods: This is a retrospective study of consecutive patients with isolated mandibular angle fractures treated using a specific protocol at a Regional Oral and Maxillofacial Department between January 1998 and December 2004. Patient demographics, fracture etiology, length of hospital stay, removal of third molar, and postoperative complications were recorded. Preoperative and postoperative inferior alveolar nerve function was recorded. Objective sensory testing and patient interviews were conducted to determine the incidence of postoperative sensory deficit. Results: The study population included 50 patients presenting with isolated mandibular angle fractures, 6 patients (12%) experienced complications requiring bone plate removal. These complications were minor and occurred after fracture healing as follows: 4 patients (8%) experienced superficial soft tissue infection associated with the bone plate, treated with oral antibiotics, 1 patient (2%) experienced bone plate exposure, and a further patient (2%) presented with a fractured bone plate. All 6 patients (12%) were treated by bone plate removal under general anesthesia as elective day case surgery. Thirty-nine (78%) patients had long-term sensory follow-up, mean 37 months (2 to 84 months). Permanent inferior alveolar sensory deficit (>12 months) was present in 4 (8%). Five of 26 (19%) patients with normal postinjury/preoperative sensory function had a postoperative sensory deficit. All patients in this group reported recovery of normal sensation within 6 months. Conclusions: The results of this study suggest that the complication rates associated with the treatment of isolated mandibular angle fractures using a superior border plating technique, in this patient population, is relatively low (12%). The complications were all minor in nature. There was a permanent (>12 months) inferior alveolar sensory deficit in 4 (8%) patients.
MeSH term(s)	Adolescent ; Adult ; Bone Plates ; Female ; Fracture Fixation, Internal/adverse effects ; Fracture Fixation, Internal/methods ; Humans ; Male ; Mandibular Fractures/surgery ; Mandibular Nerve/physiology ; Postoperative Complications/classification ; Postoperative Complications/etiology ; Retrospective Studies ; Sensation Disorders/etiology ; Surgical Wound Infection/etiology ; Treatment Outcome ; Trigeminal Nerve Injuries
Language	English
Publishing date	2007-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	392404-x
ISSN	1531-5053 ; 0278-2391
ISSN (online)	1531-5053
ISSN	0278-2391
DOI	10.1016/j.joms.2006.10.069
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Article ; Online: Postoperative radiotherapy for patients with oral squamous cell carcinoma with intermediate risk of recurrence: A case match study.

Barry, Conor P / Wong, Daniel / Clark, Jonathan R / Shaw, Richard J / Gupta, Ruta / Magennis, Patrick / Triantafyllou, Asterios / Gao, Kan / Brown, James S

Head & neck

2017 Volume 39, Issue 7, Page(s) 1399–1404

Abstract: Background: The purpose of this study was to determine the effect of postoperative radiotherapy (PORT) on recurrence and survival in patients with oral squamous cell carcinoma (OSCC) of intermediate recurrence risk.: Methods: Intermediate risk ... ...

Abstract	Background: The purpose of this study was to determine the effect of postoperative radiotherapy (PORT) on recurrence and survival in patients with oral squamous cell carcinoma (OSCC) of intermediate recurrence risk. Methods: Intermediate risk patients, defined as pT1, pT2, pN0, or pN1 with at least one adverse pathological feature (eg, lymphovascular/perineural invasion), were identified from the head and neck databases of the Liverpool Head and Neck Cancer Unit and the Sydney Head and Neck Cancer Institute. Patients who received surgery and PORT were case matched with patients treated by surgery alone based on pN, pT, margins, and pathological features. Results: Ninety patients were matched into 45 pairs. There was significant improvement (P = .039) in locoregional control with PORT (84%) compared with surgery alone (60%), which was concentrated in the pN1 subgroup (P = .036), but not the pN0 subgroup (P = .331). Conclusion: PORT significantly improves locoregional control for intermediate risk OSCC.
MeSH term(s)	Aged ; Carcinoma, Squamous Cell/mortality ; Carcinoma, Squamous Cell/radiotherapy ; Carcinoma, Squamous Cell/surgery ; Case-Control Studies ; Databases, Factual ; Disease-Free Survival ; Female ; Follow-Up Studies ; Humans ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Mouth Neoplasms/mortality ; Mouth Neoplasms/radiotherapy ; Mouth Neoplasms/surgery ; Neoplasm Recurrence, Local/epidemiology ; Neoplasm Recurrence, Local/pathology ; Radiotherapy, Adjuvant ; Reference Values ; Retrospective Studies ; Risk Assessment ; Survival Analysis ; Treatment Outcome
Language	English
Publishing date	2017
Publishing country	United States
Document type	Comparative Study ; Journal Article
ZDB-ID	645165-2
ISSN	1097-0347 ; 0148-6403 ; 1043-3074
ISSN (online)	1097-0347
ISSN	0148-6403 ; 1043-3074
DOI	10.1002/hed.24780
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Article ; Online: Results of flap reconstruction: categorisation to reflect outcomes and process in the management of head and neck defects.

Ho, M W / Nugent, M / Puglia, F / Shaw, R J / Blackburn, T K / Parmar, S / Dhanda, J / Fry, A M / Brennan, P / Barry, C P / McMahon, J

The British journal of oral & maxillofacial surgery

2019 Volume 57, Issue 9, Page(s) 935–937

Abstract: The reporting of the outcomes of flap reconstruction is often based on numerical success rates. Whilst this remains a useful variable with which to measure success, it is limited in its ability to reflect the complex processes involved. The lack of ... ...

Abstract	The reporting of the outcomes of flap reconstruction is often based on numerical success rates. Whilst this remains a useful variable with which to measure success, it is limited in its ability to reflect the complex processes involved. The lack of consistency in the categorisation of outcomes of flap reconstruction in the head and neck could potentially lead us to lose the opportunity to fully capture the implications of its success or failure, or both. We propose a classification that moves away from primarily reporting the results of its binary nature, and focuses more on the process of reconstruction, particularly in the head and neck.
MeSH term(s)	Head and Neck Neoplasms/surgery ; Humans ; Reconstructive Surgical Procedures ; Retrospective Studies ; Surgical Flaps
Language	English
Publishing date	2019-08-22
Publishing country	Scotland
Document type	Journal Article
ZDB-ID	605685-4
ISSN	1532-1940 ; 0266-4356
ISSN (online)	1532-1940
ISSN	0266-4356
DOI	10.1016/j.bjoms.2019.08.005
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