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Article ; Online: Urinary Tract Infections Treatment/Comparative Therapeutics.

Olin, Shelly J / Bartges, Joseph W

The Veterinary clinics of North America. Small animal practice

2022 Volume 52, Issue 3, Page(s) 581–608

Abstract: Urinary tract infection (UTI) is commonly encountered in small animal general practice. Within the past 5 years, there have been changes to terminology, such as the renaming of asymptomatic bacteriuria to subclinical bacteriuria, as well as paradigm ... ...

Abstract	Urinary tract infection (UTI) is commonly encountered in small animal general practice. Within the past 5 years, there have been changes to terminology, such as the renaming of asymptomatic bacteriuria to subclinical bacteriuria, as well as paradigm shifts in the management of UTI. In general, there is an emphasis for responsible antimicrobial stewardship and selecting treatment based on urine culture and sensitivity and treating symptomatic bacterial UTI with a shorter duration of antimicrobials. In addition, for most cases, treatment of subclinical bacteriuria is not indicated.
MeSH term(s)	Animals ; Anti-Bacterial Agents/therapeutic use ; Bacteria ; Bacterial Infections/veterinary ; Bacteriuria/diagnosis ; Bacteriuria/drug therapy ; Bacteriuria/veterinary ; Female ; Male ; Urinalysis/veterinary ; Urinary Tract Infections/diagnosis ; Urinary Tract Infections/drug therapy ; Urinary Tract Infections/veterinary
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2022-03-31
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	757662-6
ISSN	1878-1306 ; 0195-5616
ISSN (online)	1878-1306
ISSN	0195-5616
DOI	10.1016/j.cvsm.2022.01.002
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Article ; Online: d,l-Methionine in combination with amoxicillin-clavulanic acid successfully dissolves spontaneously occurring infection-induced struvite urocystoliths in dogs: a pilot study.

Harris, Amber S M / Bartges, Joseph W / Moyers, Tamberlyn D

Journal of the American Veterinary Medical Association

2023 Volume 261, Issue 8, Page(s) 1152–1159

Abstract: Objective: To determine the efficacy and safety of a urinary acidifier (d,l-methionine [Methio-Form]) and an antimicrobial agent (amoxicillin-clavulanic acid [Clavamox]) without changing diet for dissolving infection-induced struvite urocystoliths in ... ...

Abstract	Objective: To determine the efficacy and safety of a urinary acidifier (d,l-methionine [Methio-Form]) and an antimicrobial agent (amoxicillin-clavulanic acid [Clavamox]) without changing diet for dissolving infection-induced struvite urocystoliths in dogs. Animals: 14 dogs were recruited for this prospective study; 11 completed it and 3 dogs withdrew due to inability of the owners to administer the treatment (n = 2) or refusal of treatment by the dog (1). Procedures: All dogs were administered d,l-methionine (approx initial dose of 75 mg/kg, PO, q 12 h) and amoxicillin-clavulanic acid (22 mg/kg, PO, q 12 h) based on urine culture and sensitivity. Urine pH, urinalysis, urine culture, venous blood gas and serum biochemical analysis, and lateral survey abdominal radiographic images were evaluated initially and every 4 weeks until urolith dissolution (success) or lack of change in size and/or shape of urocystoliths on 2 consecutive reevaluation points (failure) occurred. Results: Uroliths dissolved in 8 of 11 dogs in a median of 2 months (range, 1 to 4 months) with a final effective dosage of d,l-methionine of approximately 100 mg/kg, PO, every 12 hours. In 3 dogs, uroliths failed to dissolve and were removed surgically; they contained variable amounts of calcium oxalate. No adverse events occurred. Clinical relevance: Infection-induced struvite urolithiasis is 1 of the 2 most common minerals occurring in canine uroliths. Results of this study supported the use of d,l-methionine and amoxicillin-clavulanic acid without changing diet for dissolution of infection-induced struvite urocystoliths in dogs.
MeSH term(s)	Dogs ; Animals ; Struvite ; Amoxicillin-Potassium Clavulanate Combination/therapeutic use ; Pilot Projects ; Magnesium Compounds/therapeutic use ; Methionine/therapeutic use ; Prospective Studies ; Phosphates/analysis ; Phosphates/therapeutic use ; Urinary Calculi/veterinary ; Urolithiasis/drug therapy ; Urolithiasis/veterinary ; Dog Diseases/drug therapy
Chemical Substances	Struvite (AW3EJL1462) ; Amoxicillin-Potassium Clavulanate Combination (74469-00-4) ; Magnesium Compounds ; Methionine (AE28F7PNPL) ; Phosphates
Language	English
Publishing date	2023-04-26
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	390811-2
ISSN	1943-569X ; 0003-1488
ISSN (online)	1943-569X
ISSN	0003-1488
DOI	10.2460/javma.23.02.0063
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Article ; Online: Weight measurements result in improved accuracy and precision in preparation of cooked homemade diets for dogs.

Boothby, Grace L / Parr, Jacqueline M / Bartges, Joseph W

Journal of the American Veterinary Medical Association

2022 Volume 260, Issue S3, Page(s) S46–S52

Abstract: Objective: Accurate measurement of ingredients for cooked homemade diets helps ensure diets are complete and balanced. Studies have demonstrated measuring dry dog food with measuring cups results in significant inaccuracy. Therefore, measuring ... ...

Abstract	Objective: Accurate measurement of ingredients for cooked homemade diets helps ensure diets are complete and balanced. Studies have demonstrated measuring dry dog food with measuring cups results in significant inaccuracy. Therefore, measuring ingredients by volume when preparing these diets may be inaccurate. The purpose was to determine the accuracy of preparing cooked homemade diets by measuring ingredients by volume (measuring cups and spoons) or weight (digital gram scale with a syringe for measuring oil only). Samples: 42 diet samples prepared by 21 participants. Procedures: 21 participants were instructed on homemade diet preparation based on weight or volume measurement methods. Diet samples underwent proximate analysis and mineral analysis. Data, expressed on a dry matter basis (DMB) and an energy density basis (EDB), from both groups were compared to the anticipated nutrient profile to determine which method resulted in more accuracy. Data from individual samples within each group were compared to each other to determine the precision of both methods. Results: Weight measurements were more precise for crude protein, crude fat, nitrogen-free extract, and potassium (DMB and EDB) and more accurate for ash (DMB and EDB) and iron (EDB). Comparatively, volume measurements were more precise for ash (DMB) and more accurate for iron (DMB). Clinical relevance: Findings suggest weight measurements should be utilized to prepare cooked homemade diets for dogs to promote precision and accuracy.
MeSH term(s)	Dogs ; Animals ; Animal Feed/analysis ; Diet/veterinary ; Iron
Chemical Substances	Iron (E1UOL152H7)
Language	English
Publishing date	2022-10-26
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	390811-2
ISSN	1943-569X ; 0003-1488
ISSN (online)	1943-569X
ISSN	0003-1488
DOI	10.2460/javma.22.07.0283
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Article ; Online: Feline Calcium Oxalate Urolithiasis: Risk factors and rational treatment approaches.

Bartges, Joseph W

Journal of feline medicine and surgery

2016 Volume 18, Issue 9, Page(s) 712–722

Abstract: Practical relevance: Uroliths occur commonly in the bladder and/or urethra of cats and can be lifethreatening if urethral obstruction occurs. Calcium oxalate accounts for 40-50% of urocystoliths and these stones are not amenable to medical dissolution; ... ...

Abstract	Practical relevance: Uroliths occur commonly in the bladder and/or urethra of cats and can be lifethreatening if urethral obstruction occurs. Calcium oxalate accounts for 40-50% of urocystoliths and these stones are not amenable to medical dissolution; therefore, removal by surgery or minimally invasive techniques is required if uroliths must be treated. Medical protocols for prevention involve decreasing urine saturation for minerals that form uroliths. Etiopathogenesis: Formation of uroliths is not a disease, but rather a complication of several disorders. Some disorders can be identified and corrected (such as infection-induced struvite urolith formation); others can be identified but not corrected (such as idiopathic hypercalcemia). In most cats with calcium oxalate urolith formation the underlying etiopathogenesis is not known. A common denominator of all these disorders is that they can from time to time create oversaturation of urine with one or more crystal precursors, resulting in formation of crystals. Basic concepts: In order to develop rational and effective approaches to treatment, abnormalities that promote urolith formation must be identified, with the goal of eliminating or modifying them. It is important, therefore, to understand several basic concepts associated with urolithiasis and the factors that promote urolith formation that may be modified with medical treatment; for example, the state of urinary saturation, modifiers of crystal formation, potential for multiple crystal types, and presence of bacterial infection or urinary obstruction.
MeSH term(s)	Animals ; Calcium Oxalate/metabolism ; Cat Diseases/metabolism ; Cat Diseases/therapy ; Cats ; Risk Factors ; Urolithiasis/metabolism ; Urolithiasis/therapy ; Urolithiasis/veterinary
Chemical Substances	Calcium Oxalate (2612HC57YE)
Language	English
Publishing date	2016-08-26
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2049047-1
ISSN	1532-2750 ; 1098-612X
ISSN (online)	1532-2750
ISSN	1098-612X
DOI	10.1177/1098612X16660442
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Article ; Online: Urology: It's Gold for a Reason!

Bartges, Joseph W

The Veterinary clinics of North America. Small animal practice

2015 Volume 45, Issue 4, Page(s) ix–x

MeSH term(s)	Animals ; Cat Diseases/diagnosis ; Cat Diseases/prevention & control ; Cat Diseases/therapy ; Cats ; Dog Diseases/diagnosis ; Dog Diseases/prevention & control ; Dog Diseases/therapy ; Dogs ; Urinary Tract/pathology ; Urologic Diseases/diagnosis ; Urologic Diseases/therapy ; Urologic Diseases/veterinary
Language	English
Publishing date	2015-07
Publishing country	United States
Document type	Introductory Journal Article
ZDB-ID	757662-6
ISSN	1878-1306 ; 0195-5616
ISSN (online)	1878-1306
ISSN	0195-5616
DOI	10.1016/j.cvsm.2015.03.002
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Article ; Online: Association of four differently processed diets with plasma and urine advanced glycation end products and serum soluble receptor for advanced glycation end products concentration in healthy dogs.

Bridglalsingh, Siobhan / Archer-Hartmann, Stephanie / Azadi, Parastoo / Barbier de La Serre, Claire / Remillard, Rebecca L / Sunvold, Gregory D / Bartges, Joseph W

Journal of animal physiology and animal nutrition

2024 Volume 108, Issue 3, Page(s) 735–751

Abstract: Advanced glycation end products (AGEs), formed via the Maillard reaction (MR) during processing of foods, have been implicated in inflammatory and degenerative diseases in human beings. Cellular damage is primarily caused by AGE binding with the receptor ...

Abstract	Advanced glycation end products (AGEs), formed via the Maillard reaction (MR) during processing of foods, have been implicated in inflammatory and degenerative diseases in human beings. Cellular damage is primarily caused by AGE binding with the receptor for AGEs (RAGE) on cell membranes. An isoform of RAGE, soluble RAGE (sRAGE), acts as a decoy receptor binding circulating AGEs preventing cellular activation. Pet food manufacturing involves processing methods similar to human food processing that may increase dietary AGEs (dAGEs). We hypothesized that diet, plasma and urine AGEs, and serum sRAGE concentrations would differ between thermally processed diets. This study examined the association of four differently processed diets: ultra-processed canned wet food (WF); ultra-processed dry food (DF); moderately processed air-dried food (ADF) and minimally processed mildly cooked food (MF) on total plasma levels of the AGEs, carboxymethyllysine (CML), carboxyethyllysine (CEL), methylglyoxal hydroimidazolone-1, glyoxal hydroimidazolone-1, argpyrimidine, urine CML, CEL and lysinoalanine, and serum sRAGE concentration. Ultra-high-performance liquid chromatography-tandem mass spectrometry was used to measure AGEs. sRAGE concentration was measured using a commercial canine-specific enzyme-linked immunosorbent assay kit. Total dAGEs (mg/100 kcal as fed) were higher in WF than in other diets. Plasma total AGEs (nM/50 μL) were significantly higher with WF, with no difference found between DF, ADF, and MF; however, ADF was significantly higher than MF. Urine CML (nmol AGEs/mmol creatinine) was significantly higher with DF than with WF and MF. There were no significant differences in total urine AGEs or serum sRAGE concentration between diets. In conclusion, different methods of processing pet foods are associated with varied quantities of AGEs influencing total plasma AGE concentration in healthy dogs. Serum sRAGE concentration did not vary across diets but differences in total AGE/sRAGE ratio were observed between MF and WF and, ADF and DF.
MeSH term(s)	Animals ; Glycation End Products, Advanced/blood ; Glycation End Products, Advanced/urine ; Dogs/urine ; Dogs/blood ; Animal Feed/analysis ; Receptor for Advanced Glycation End Products/blood ; Receptor for Advanced Glycation End Products/metabolism ; Diet/veterinary ; Food Handling ; Male ; Female
Chemical Substances	Glycation End Products, Advanced ; Receptor for Advanced Glycation End Products
Language	English
Publishing date	2024-01-27
Publishing country	Germany
Document type	Journal Article ; Randomized Controlled Trial, Veterinary
ZDB-ID	232729-6
ISSN	1439-0396 ; 0044-3565 ; 0931-2439
ISSN (online)	1439-0396
ISSN	0044-3565 ; 0931-2439
DOI	10.1111/jpn.13927
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Book: Urology

Bartges, Joseph W

(The veterinary clinics of North America : Small animal practice ; 45,4)

2015

Author's details	ed.: Joseph W. Bartges
Series title	The veterinary clinics of North America : Small animal practice ; 45,4
Language	English
Size	X S., S. 622-894, Ill., graph. Darst.
Publisher	Elsevier
Publishing place	Philadelphie, Pa
Document type	Book
Note	Literaturangaben
ISBN	9780323391481 ; 0323391486
Database	Special collection on veterinary medicine and general parasitology

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Article: Feline Calcium Oxalate Urolithiasis

Bartges, Joseph W

Journal of feline medicine and surgery. , v. 18, no. 9

Risk factors and rational treatment approaches

2016

Abstract: Uroliths occur commonly in the bladder and/or urethra of cats and can be lifethreatening if urethral obstruction occurs. Calcium oxalate accounts for 40–50% of urocystoliths and these stones are not amenable to medical dissolution; therefore, removal by ... ...

Abstract	Uroliths occur commonly in the bladder and/or urethra of cats and can be lifethreatening if urethral obstruction occurs. Calcium oxalate accounts for 40–50% of urocystoliths and these stones are not amenable to medical dissolution; therefore, removal by surgery or minimally invasive techniques is required if uroliths must be treated. Medical protocols for prevention involve decreasing urine saturation for minerals that form uroliths. Formation of uroliths is not a disease, but rather a complication of several disorders. Some disorders can be identified and corrected (such as infection-induced struvite urolith formation); others can be identified but not corrected (such as idiopathic hypercalcemia). In most cats with calcium oxalate urolith formation the underlying etiopathogenesis is not known. A common denominator of all these disorders is that they can from time to time create oversaturation of urine with one or more crystal precursors, resulting in formation of crystals. In order to develop rational and effective approaches to treatment, abnormalities that promote urolith formation must be identified, with the goal of eliminating or modifying them. It is important, therefore, to understand several basic concepts associated with urolithiasis and the factors that promote urolith formation that may be modified with medical treatment; for example, the state of urinary saturation, modifiers of crystal formation, potential for multiple crystal types, and presence of bacterial infection or urinary obstruction.
Keywords	bacterial infections ; bladder ; bladder calculi ; calcium oxalate ; cats ; crystals ; hypercalcemia ; magnesium ammonium phosphate ; medical treatment ; minerals ; surgery ; urethra ; urine
Language	English
Dates of publication	2016-09
Size	p. 712-722.
Publishing place	SAGE Publications
Document type	Article
ZDB-ID	2049047-1
ISSN	1532-2750 ; 1098-612X
ISSN (online)	1532-2750
ISSN	1098-612X
DOI	10.1177/1098612X16660442
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Chronic kidney disease in dogs and cats.

Bartges, Joseph W

The Veterinary clinics of North America. Small animal practice

2012 Volume 42, Issue 4, Page(s) 669–92, vi

Abstract: Chronic kidney disease (CKD) occurs commonly in older dogs and cats. Advances in diagnostics, staging, and treatment are associated with increased quality and quantity of life. Dietary modification has been shown to increase survival and quality of life ... ...

Abstract	Chronic kidney disease (CKD) occurs commonly in older dogs and cats. Advances in diagnostics, staging, and treatment are associated with increased quality and quantity of life. Dietary modification has been shown to increase survival and quality of life and involves more than protein restriction as diets modified for use with CKD are lower in phosphorous and sodium, potassium and B-vitamin replete, and alkalinizing, and they contain n3-fatty acids. Additionally, recognition and management of CKD-associated diseases such as systemic arterial hypertension, proteinuria, and anemia benefit patients. This article summarizes staging and management of CKD in dogs and cats.
MeSH term(s)	Acid-Base Imbalance/prevention & control ; Acid-Base Imbalance/veterinary ; Animals ; Cat Diseases/therapy ; Cats ; Disease Progression ; Dog Diseases/therapy ; Dogs ; Kidney Failure, Chronic/therapy ; Kidney Failure, Chronic/veterinary ; Nutritional Support/veterinary ; Prevalence ; Water-Electrolyte Imbalance/prevention & control ; Water-Electrolyte Imbalance/veterinary
Language	English
Publishing date	2012-07
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	757662-6
ISSN	1878-1306 ; 0195-5616
ISSN (online)	1878-1306
ISSN	0195-5616
DOI	10.1016/j.cvsm.2012.04.008
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Article ; Online: Management of a urethral tear with porcine small intestinal submucosa-augmented urethroplasty and balloon dilation for subsequent urethral stricture in a cat.

Dickerson, Vanna M / Grimes, Janet A / Hill, Tracy L / Bartges, Joseph W / Schmiedt, Chad W

Journal of the American Veterinary Medical Association

2021 Volume 258, Issue 2, Page(s) 186–191

Abstract: Case description: As a result of vehicular trauma, a 3-year-old neutered male domestic shorthair cat sustained luxation of the sacrocaudal joint and a urethral tear.: Clinical findings: Retrograde contrast urethrocystography revealed a urethral tear ... ...

Abstract	Case description: As a result of vehicular trauma, a 3-year-old neutered male domestic shorthair cat sustained luxation of the sacrocaudal joint and a urethral tear. Clinical findings: Retrograde contrast urethrocystography revealed a urethral tear at the level of the ischiatic tuberosity. Conservative treatment for 7 days with a urethral catheter was unsuccessful. Treatment and outcome: An approach for a perineal urethrostomy was performed and revealed a large urethral tear (4 mm in length in a craniocaudal orientation and encompassing approx 50% of the urethral circumference) proximal to the bulbourethral glands. Urethroplasty was performed with a graft of a rectangular section of single-layer porcine small intestinal submucosa. Perineal urethrostomy was then completed routinely, and a urethral catheter was left in place for 5 days. Two days after removal of the urethral catheter, stranguria was noted. Retrograde contrast urethrocystography revealed a urethral stricture. Balloon dilation of the urethral stricture was performed, and the cat's stranguria improved. Ten weeks following balloon dilation, the cat developed hematuria, and a urinary tract infection and urethral stricture were diagnosed. Balloon dilation was repeated with instillation of triamcinolone solution at the stricture site. Eighteen months later (approx 21 months after the initial surgery), the cat was urinating normally. Clinical relevance: The outcome for the cat of this report indicated that porcine small intestinal submucosa may be used to successfully augment urethroplasty for treatment of traumatic urethral tears in cats. Urethral balloon dilation with triamcinolone instillation may be used to treat postoperative urethral strictures.
MeSH term(s)	Animals ; Cat Diseases/surgery ; Catheterization/veterinary ; Cats ; Dilatation/veterinary ; Male ; Swine ; Swine Diseases ; Treatment Outcome ; Urethra/surgery ; Urethral Stricture/surgery ; Urethral Stricture/veterinary ; Urologic Surgical Procedures/veterinary
Language	English
Publishing date	2021-01-06
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	390811-2
ISSN	1943-569X ; 0003-1488
ISSN (online)	1943-569X
ISSN	0003-1488
DOI	10.2460/javma.258.2.186
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