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  1. AU="Bartolomé-Comas, Rosa"
  2. AU="Mathew, Josey"
  3. AU="Ali A. Shati"
  4. AU="Tavares, Guilherme M"
  5. AU="Deoni, Sean"
  6. AU="Byrne, Michael E"
  7. AU=Edwards Adrianne N.
  8. AU=Mehr Reyhaneh Niayesh
  9. AU="Par-Young, Jennefer"
  10. AU="Yon, Yongjie"
  11. AU="Laisi, Arttu"
  12. AU="Huang, Haibing"
  13. AU="Volk, Michelle"
  14. AU="Zijlstra, J. G."
  15. AU="Aditya Narayan"
  16. AU="Soliño, S. López"
  17. AU="Bervoets, Lieven"
  18. AU=Perween Reshma AU=Perween Reshma
  19. AU="Wang, Zhenduo"

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  1. Artikel ; Online: Impact of an outpatient parenteral antimicrobial treatment (OPAT) as part of a paediatric-specific PROA program.

    Fernández-Polo, Aurora / Ramon-Cortes, Sonia / Plaja-Dorca, Judith / Bartolomé-Comas, Rosa / Vidal-Valdivia, Lis / Soler-Palacín, Pere

    Enfermedades infecciosas y microbiologia clinica (English ed.)

    2022  Band 41, Heft 4, Seite(n) 230–234

    Abstract: Introduction: Outpatient parenteral antimicrobial treatment (OPAT) is an alternative to in-patient care in carefully selected patients. This study presents a self-administration OPAT program integrated within the pediatric antibiotic stewardship program ...

    Abstract Introduction: Outpatient parenteral antimicrobial treatment (OPAT) is an alternative to in-patient care in carefully selected patients. This study presents a self-administration OPAT program integrated within the pediatric antibiotic stewardship program (ASP) in a pediatric tertiary care center.
    Material and methods: Descriptive, retrospective and unicentric study. Data from all patients under 20 years of age who were prescribed treatment by a pediatric unit during 2019 and 2020 were included. Data regarding number of saved beds and estimating the opportunity cost of the OPAT program for the hospital were analyzed.
    Results: Fifty-seven patients received 106 episodes of treatment. Favorable clinical outcome occurred in 74.5% of the episodes. The main cause of premature interruption was unfavorable clinical outcome of the infection (37.1%). A total of 2.62 beds/day were saved, resulting in an economic benefit of 1,069,963 €.
    Conclusion: A self-administration OPAT program integrated within the pediatric ASP has proven to be safe and effective and provides economic benefits.
    Mesh-Begriff(e) Humans ; Child ; Outpatients ; Anti-Bacterial Agents/therapeutic use ; Retrospective Studies ; Anti-Infective Agents/therapeutic use ; Ambulatory Care/methods
    Chemische Substanzen Anti-Bacterial Agents ; Anti-Infective Agents
    Sprache Englisch
    Erscheinungsdatum 2022-08-10
    Erscheinungsland Spain
    Dokumenttyp Journal Article
    ISSN 2529-993X
    ISSN (online) 2529-993X
    DOI 10.1016/j.eimce.2022.08.004
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel: A propósito de un paciente con infección por Salmonella enterica serotipo typhi resistente al ácido nalidíxico. Indicación terapéutica.

    González-López, Juan José / Larrosa, Nieves / Planes, Ana M / Bartolomé-Comas, Rosa M

    Enfermedades infecciosas y microbiologia clinica

    2007  Band 25, Heft 10, Seite(n) 655–656

    Titelübersetzung About a patient with nalidixic-acid-resistant Salmonella enterica serotype typhi infection. Therapeutic management.
    Mesh-Begriff(e) Adolescent ; Bacteremia/drug therapy ; Bacteremia/microbiology ; Bacterial Proteins/genetics ; Campylobacter Infections/complications ; Campylobacter Infections/drug therapy ; Campylobacter jejuni ; DNA Gyrase/genetics ; Drug Resistance, Microbial/genetics ; Gastroenteritis/drug therapy ; Gastroenteritis/microbiology ; Humans ; Male ; Mutation, Missense ; Nalidixic Acid/pharmacology ; Nalidixic Acid/therapeutic use ; Pakistan/ethnology ; Salmonella typhi/drug effects ; Salmonella typhi/genetics ; Trimethoprim, Sulfamethoxazole Drug Combination/therapeutic use ; Typhoid Fever/diagnosis ; Typhoid Fever/drug therapy ; Typhoid Fever/microbiology
    Chemische Substanzen Bacterial Proteins ; Nalidixic Acid (3B91HWA56M) ; Trimethoprim, Sulfamethoxazole Drug Combination (8064-90-2) ; DNA Gyrase (EC 5.99.1.3)
    Sprache Spanisch
    Erscheinungsdatum 2007-12
    Erscheinungsland Spain
    Dokumenttyp Case Reports ; Letter
    ZDB-ID 1070941-1
    ISSN 1578-1852 ; 0213-005X
    ISSN (online) 1578-1852
    ISSN 0213-005X
    DOI 10.1157/13112944
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Neisseria gonorrhoeae: resistencias antimicrobianas y estudio de la dinámica poblacional. Situación en 2011 en Barcelona.

    Serra-Pladevall, Judit / Barberá-Gracia, María Jesús / Roig-Carbajosa, Glòria / Juvé-Saumell, Rosa / Gonzalez-Lopez, Juan José / Bartolomé-Comas, Rosa / Andreu-Domingo, Antònia

    Enfermedades infecciosas y microbiologia clinica

    2013  Band 31, Heft 9, Seite(n) 579–583

    Abstract: Background: Due to the high rates of antimicrobial resistance to certain antibiotics, together with the emergence of Neisseria gonorrhoeae (NG) with reduced susceptibility and resistance to third-generation cephalosporins, gonococcal infection is ... ...

    Titelübersetzung Neisseria gonorrhoeae: antimicrobial resistance and study of population dynamics. Situation in Barcelona in 2011.
    Abstract Background: Due to the high rates of antimicrobial resistance to certain antibiotics, together with the emergence of Neisseria gonorrhoeae (NG) with reduced susceptibility and resistance to third-generation cephalosporins, gonococcal infection is becoming a public health problem. The objectives of the study were: To keep track of the antimicrobial susceptibility of NG strains obtained from January to August 2011. To study the population dynamics.
    Methods: The antimicrobial susceptibility was studied by disk-diffusion and E-test. The genotyping was performed by NG-MAST method.
    Results: Of a total of 100strains studied, 59% showed intermediate sensitivity to penicillin and 9% were resistant. According to EUCAST, we detected 3gonococci with reduced susceptibility to ceftriaxone, 10 to cefixime and one with high-level resistance to both antibiotics (MIC 1.5μg/ml). MIC50 and MIC90 to cefixime were 0.016 and 0.125μg/ml, respectively, whereas to ceftriaxone they were <0.016 and 0.064μg/ml, respectively. Almost all (99%) of the strains were resistant to doxycycline, 53% to ciprofloxacin, 3% to azithromycin, and 1% to spectinomycin. The most prevalent ST was ST1407, predominantly associated to resistance or reduced sensitivity to cephalosporins or macrolides.
    Conclusions: NG has developed significant rates of resistance to various antibiotics. One strain has been detected with high level resistance to third generation cephalosporins, and several strains with reduced susceptibility. An increase in MIC50 and MIC90 to these antibiotics has also been observed. NG population structure remains stable and common to the rest of Europe, although two new ST (ST7226 and ST7227) have been identified that could be selected and acquire high levels of resistance to cephalosporins.
    Mesh-Begriff(e) Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Drug Resistance, Bacterial ; Female ; Gonorrhea/drug therapy ; Gonorrhea/epidemiology ; Humans ; Male ; Microbial Sensitivity Tests ; Neisseria gonorrhoeae/drug effects ; Population Dynamics ; Spain
    Chemische Substanzen Anti-Bacterial Agents
    Sprache Spanisch
    Erscheinungsdatum 2013-11
    Erscheinungsland Spain
    Dokumenttyp English Abstract ; Journal Article
    ZDB-ID 1070941-1
    ISSN 1578-1852 ; 0213-005X
    ISSN (online) 1578-1852
    ISSN 0213-005X
    DOI 10.1016/j.eimc.2013.03.010
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Verfügbar in ZB MED Köln/Königswinter

    Zs.A 3204: Hefte anzeigen Standort:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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