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Article ; Online: LUMiC® endoprosthesis for pelvic reconstruction: A Canadian experience.

Rizkallah, Maroun / Ferguson, Peter C / Basile, Georges / Kim, Paul / Werier, Joel / Wilson, David / Turcotte, Robert

2022 Volume 127, Issue 4, Page(s) 727–733

Abstract: Background and objectives: The LUMiC® prosthesis was introduced to reduce the mechanical complications encountered with periacetabular reconstruction after pelvic tumor resection. Few have evaluated the outcomes associated with its use.: Methods: A ... ...

Abstract	Background and objectives: The LUMiC® prosthesis was introduced to reduce the mechanical complications encountered with periacetabular reconstruction after pelvic tumor resection. Few have evaluated the outcomes associated with its use. Methods: A retrospective study from five Orthopedic Oncology Canadian centers was conducted. All patients with a LUMiC® endoprosthesis were included. Their charts were reviewed for surgical and functional outcomes. Results: A total of 16 patients were followed for 28 months (3-60). A total of 12 patients (75%) had a LUMiC® after a resection of a primary sarcoma. Mean surgical time was 555 min. Four patients (25%) had a two-stages procedure. MSTS score was 60.3 preoperatively and 54.3 postoperatively. Patients got a dual mobility bearing and the silver coated implant was used in 7 patients (43.7%). Five patients (31.3%) underwent capsular reconstruction using a fabric. Silver-coating was not found to reduce infection risk (p = 0.61) and capsuloplasty did not prevent dislocation (p = 0.6). Five patients had peroperative complications (31.3%). Eight patients (50%) had an infection including all four with two-stages surgery. Dislocation occurred in five patients (31.3%) whereas no cases of aseptic loosening were reported. A total of 10 patients (62.5%) needed a reoperation. Conclusion: LUMiC® endoprosthesis provides low rates of aseptic loosening on medium-term follow-up. Infection and dislocation are common complications but we were unable to show benefits of capsuloplasty and silver-coated implants.
MeSH term(s)	Humans ; Retrospective Studies ; Silver ; Bone Neoplasms/surgery ; Bone Neoplasms/pathology ; Canada ; Artificial Limbs ; Reoperation ; Treatment Outcome ; Prosthesis Failure ; Prosthesis Design
Chemical Substances	Silver (3M4G523W1G)
Language	English
Publishing date	2022-12-22
Publishing country	United States
Document type	Journal Article
ZDB-ID	82063-5
ISSN	1096-9098 ; 0022-4790
ISSN (online)	1096-9098
ISSN	0022-4790
DOI	10.1002/jso.27181
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Article ; Online: Outcome After Surgical Treatment of Dermatofibrosarcoma Protuberans (DFSP): Does it Require Extensive Follow-up and What is an Adequate Resection Margin?

Alshaygy, Ibrahim / Mattei, Jean-Camille / Basile, Georges / Griffin, Anthony M / Gladdy, Rebecca A / Swallow, Carol J / Dickson, Brendan C / Wunder, Jay S / Ferguson, Peter C

Annals of surgical oncology

2023 Volume 30, Issue 5, Page(s) 3106–3113

Abstract: Introduction: Dermatofibrosarcoma protuberans (DFSP) is a rare cutaneous tumour of indeterminate malignant potential. The mainstay treatment for DFSP is surgical resection. Given the reported high local recurrence rate, the ideal resection margin for ... ...

Abstract	Introduction: Dermatofibrosarcoma protuberans (DFSP) is a rare cutaneous tumour of indeterminate malignant potential. The mainstay treatment for DFSP is surgical resection. Given the reported high local recurrence rate, the ideal resection margin for DFSP is unclear. The purpose of this study was to ascertain the local recurrence and metastatic rate of DFSP and DFSP with fibrosarcomatous degeneration (FS-DFSP), with specific attention to margin status in an attempt to address the issue of margin adequacy. Methods: Patients treated for DFSP at a single sarcoma centre were identified from a prospective database. DFSP and FS-DFSP patients with and without prior surgery were included. Patients were followed after surgery to monitor complications, local recurrence and metastasis. Results: The study included 200 patients: 166 patients with DFSP and 34 patients with FS-DFSP. In the DFSP group, nine patients (5.4%) had positive margins, one case (0.6%) developed local recurrence (LR) and no patients developed distant metastases. In the FS-DFSP group, seven patients (20.6%) had positive margins, six patients (17.6%) developed local recurrence (LR) and eight patients (23.5%) developed distant metastases, of which three (37.5%) were in the lungs, one (12.5%) in bone and four (50%) in other soft tissue sites. Discussion and conclusion: Local recurrence and metastases are extremely rare in patients with DFSP. Achieving a negative as opposed to a wide surgical margin may be sufficient to avoid local recurrence of most DFSP. We suggest that no ongoing surveillance for local or systemic relapse is required for DFSP patients after negative margin resection. For FS-DFSP, we recommend the same surveillance schedule, based on tumour grade, as other soft tissue sarcoma.
MeSH term(s)	Humans ; Dermatofibrosarcoma/surgery ; Dermatofibrosarcoma/pathology ; Margins of Excision ; Follow-Up Studies ; Prognosis ; Neoplasm Recurrence, Local/pathology ; Skin Neoplasms/surgery ; Skin Neoplasms/pathology ; Sarcoma ; Soft Tissue Neoplasms
Language	English
Publishing date	2023-01-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	1200469-8
ISSN	1534-4681 ; 1068-9265
ISSN (online)	1534-4681
ISSN	1068-9265
DOI	10.1245/s10434-022-12953-8
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Article ; Online: Curability of patients with lymph node metastases from extremity soft-tissue sarcoma.

Basile, Georges / Mattei, Jean-Camille / Alshaygy, Ibrahim / Griffin, Anthony M / Catton, Charles N / Chung, Peter W / Shultz, David B / Razak, Albiruni R A / Demicco, Elizabeth G / Ferguson, Peter C / Wunder, Jay S

Cancer

2020 Volume 126, Issue 23, Page(s) 5098–5108

Abstract: Background: Lymph node metastases (LNM) rarely occur in adult extremity soft-tissue sarcoma (STS), affecting approximately 5% of patients. To the authors' knowledge, few studies to date have evaluated the prognosis and survival of patients with LNM.: ... ...

Abstract	Background: Lymph node metastases (LNM) rarely occur in adult extremity soft-tissue sarcoma (STS), affecting approximately 5% of patients. To the authors' knowledge, few studies to date have evaluated the prognosis and survival of patients with LNM. Methods: A retrospective review was performed of a single-center, prospectively collected STS database. Demographic, treatment, and oncologic data for patients with STS of the extremity with LNM were obtained from clinical and radiographic records. Results: Of 2689 patients with extremity STS, a total of 120 patients (4.5%) were diagnosed with LNM. LNM occurred most frequently among patients diagnosed with clear cell sarcoma (27.6%), epithelioid sarcoma (21.9%), rhabdomyosarcoma (17.3%), angiosarcoma (14.0%), and extraskeletal myxoid chondrosarcoma (9.3%). A total of 98 patients (81.7%) underwent LNM surgical resection. Patients with isolated LNM had a greater 5-year overall survival (57.3%) compared with patients with American Joint Committee on Cancer (AJCC) eighth edition stage IV STS with only systemic metastases (14.6%) or both LNM and systemic disease (0%; P < .0001). Patients with isolated LNM had an overall survival rate (52.9%) similar to that of patients with localized AJCC stage III tumors (ie, large, high-grade tumors) (49.3%) (P = .8). Patients with late, isolated, metachronous LNM had a 5-year overall survival rate (61.2%) that was similar to that of patients with isolated synchronous LNM at the time of presentation (53.6%) (P = .4). Conclusions: Many different types of STS develop LNM. Patients with extremity STS with isolated LNM should not be considered as having stage IV disease as they are according to the current AJCC eighth edition classification because they have significantly better survival than those with systemic metastases. Patients with isolated, late, metachronous LNM have a survival similar to that of patients with isolated synchronous LNM at the time of presentation. Lay summary: The results of the current study demonstrated that patients diagnosed with isolated lymph node metastases have a prognosis similar to that of patients diagnosed with localized American Joint Committee on Cancer stage III soft-tissue sarcomas, which also equates to a significantly better overall survival compared with patients with systemic metastases. Therefore, the authors recommend modifications to the most recent eighth edition of the American Joint Committee on Cancer staging system to clearly distinguish patients with isolated lymph node metastases to acknowledge their better prognosis compared with those with systemic metastases.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; Extremities/pathology ; Female ; Humans ; Lymph Node Excision ; Lymphatic Metastasis/pathology ; Lymphatic Metastasis/therapy ; Male ; Middle Aged ; Retrospective Studies ; Sarcoma/mortality ; Sarcoma/pathology ; Sarcoma/therapy ; Soft Tissue Neoplasms/mortality ; Soft Tissue Neoplasms/pathology ; Soft Tissue Neoplasms/therapy ; Survival Rate ; Young Adult
Language	English
Publishing date	2020-09-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	1429-1
ISSN	1097-0142 ; 0008-543X ; 1934-662X
ISSN (online)	1097-0142
ISSN	0008-543X ; 1934-662X
DOI	10.1002/cncr.33189
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Article ; Online: Intermuscular extremity myxoid liposarcoma can be managed by marginal resection following neoadjuvant radiotherapy.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

2022 Volume 49, Issue 2, Page(s) 362–367

Abstract: Background: Compared with other soft tissue sarcomas, myxoid liposarcoma (MLS) occurs in younger patients, has a propensity for intermuscular locations and is highly radiosensitive. With pre-operative radiotherapy, intermuscular MLS demonstrates ... ...

Abstract	Background: Compared with other soft tissue sarcomas, myxoid liposarcoma (MLS) occurs in younger patients, has a propensity for intermuscular locations and is highly radiosensitive. With pre-operative radiotherapy, intermuscular MLS demonstrates substantial volume reduction and can be easily separated from surrounding tissues during resection. However, it is unclear whether marginal excision of MLS is oncologically safe. This study aimed to assess the association between margins and survival in irradiated, intermuscular MLS. Methods: The study identified 198 patients from seven sarcoma centres with a first presentation of localized, extremity, intermuscular MLS that received pre-operative radiotherapy and was diagnosed between 1990 and 2017. Patient and treatment characteristics, radiological and histological responses to neoadjuvant treatment and clinical surveillance were recorded. Results: Margins were microscopically positive in 11% (n = 22), <1.0 mm in 15% (n = 29) and ≥1.0 mm in 72% (n = 143). There was no association between margin status and local recurrence-free, metastasis-free or overall survival. This finding held true even in patients at higher risk of worse overall survival based on multivariable analysis (% round cell≥5%, percentage ellipsoid tumour volume change ≤ -60.1%). Conclusion: Irradiated, extremity, intermuscular myxoid liposarcoma can safely undergo marginal resection without compromising oncologic control.
MeSH term(s)	Adult ; Humans ; Liposarcoma, Myxoid/pathology ; Neoadjuvant Therapy ; Treatment Outcome ; Liposarcoma ; Extremities/pathology ; Sarcoma/surgery ; Soft Tissue Neoplasms/surgery ; Retrospective Studies ; Neoplasm Recurrence, Local/surgery
Language	English
Publishing date	2022-09-27
Publishing country	England
Document type	Journal Article
ZDB-ID	632519-1
ISSN	1532-2157 ; 0748-7983
ISSN (online)	1532-2157
ISSN	0748-7983
DOI	10.1016/j.ejso.2022.09.008
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Zs.A 1149: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article: Roughness of simulated surfaces examined with a haptic tool: effects of spatial period, friction, and resistance amplitude

Smith, Allan M / Basile, Georges / Theriault-Groom, Jonathan / Fortier-Poisson, Pascal / Campion, Gianni / Hayward, Vincent

Experimental brain research. 2010 Apr., v. 202, no. 1

2010

Abstract: A specifically designed force-feedback device accurately simulated textures consisting of lateral forces opposing motion, simulating friction. The textures were either periodic trapezoidal forces, or sinusoidal forces spaced at various intervals from 1.5 ...

Abstract	A specifically designed force-feedback device accurately simulated textures consisting of lateral forces opposing motion, simulating friction. The textures were either periodic trapezoidal forces, or sinusoidal forces spaced at various intervals from 1.5 mm to 8.5 mm. In each of two experiments, 10 subjects interacted with the virtual surfaces using the index finger placed on a mobile plate that produced the forces. The subjects selected their own speed and contact force for exploring the test surface. The apparatus returned force fields as a function of both the finger position and the force normal to the skin allowing full control over the tangential interaction force. In Experiment #1, subjects used an integer, numerical scale of their own choosing to rate the roughness of eight identical, varyingly spaced force ramps superimposed on a background resistance. The results indicated that subjective roughness was significantly, but negatively, correlated (mean r = −0.84) with the spatial period of the resistances for all subjects. In a second experiment, subjects evaluated the roughness of 80 different sinusoidal modulated force fields, which included 4 levels of resistance amplitude, 4 levels of baseline friction, and 5 spatial periods. Multiple regression was used to determine the relationship between friction, tangential force amplitude, and spatial period to roughness. Together, friction and tangential force amplitude produced a combined correlation of 0.70 with subjective roughness. The addition of spatial period only increased the multiple regression correlation to 0.71. The correlation between roughness estimates and the rate of change in tangential force was 0.72 in Experiment #1 and 0.57 in Experiment #2. The results suggest that the sensation of roughness is strongly influenced by friction and tangential force amplitude, whereas the spatial period of simulated texture alone makes a negligible contribution to the sensation of roughness.
Language	English
Dates of publication	2010-04
Size	p. 33-43.
Publisher	Springer-Verlag
Publishing place	Berlin/Heidelberg
Document type	Article
ZDB-ID	1201-4
ISSN	1432-1106 ; 0014-4819
ISSN (online)	1432-1106
ISSN	0014-4819
DOI	10.1007/s00221-009-2105-x
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Roughness of simulated surfaces examined with a haptic tool: effects of spatial period, friction, and resistance amplitude.

Smith, Allan M / Basile, Georges / Theriault-Groom, Jonathan / Fortier-Poisson, Pascal / Campion, Gianni / Hayward, Vincent

Experimental brain research

2009 Volume 202, Issue 1, Page(s) 33–43

Abstract	A specifically designed force-feedback device accurately simulated textures consisting of lateral forces opposing motion, simulating friction. The textures were either periodic trapezoidal forces, or sinusoidal forces spaced at various intervals from 1.5 mm to 8.5 mm. In each of two experiments, 10 subjects interacted with the virtual surfaces using the index finger placed on a mobile plate that produced the forces. The subjects selected their own speed and contact force for exploring the test surface. The apparatus returned force fields as a function of both the finger position and the force normal to the skin allowing full control over the tangential interaction force. In Experiment #1, subjects used an integer, numerical scale of their own choosing to rate the roughness of eight identical, varyingly spaced force ramps superimposed on a background resistance. The results indicated that subjective roughness was significantly, but negatively, correlated (mean r = -0.84) with the spatial period of the resistances for all subjects. In a second experiment, subjects evaluated the roughness of 80 different sinusoidal modulated force fields, which included 4 levels of resistance amplitude, 4 levels of baseline friction, and 5 spatial periods. Multiple regression was used to determine the relationship between friction, tangential force amplitude, and spatial period to roughness. Together, friction and tangential force amplitude produced a combined correlation of 0.70 with subjective roughness. The addition of spatial period only increased the multiple regression correlation to 0.71. The correlation between roughness estimates and the rate of change in tangential force was 0.72 in Experiment #1 and 0.57 in Experiment #2. The results suggest that the sensation of roughness is strongly influenced by friction and tangential force amplitude, whereas the spatial period of simulated texture alone makes a negligible contribution to the sensation of roughness.
MeSH term(s)	Adolescent ; Adult ; Computer Simulation ; Feedback ; Female ; Fingers ; Friction ; Humans ; Male ; Regression Analysis ; Touch ; Touch Perception ; User-Computer Interface ; Young Adult
Language	English
Publishing date	2009-12-11
Publishing country	Germany
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1201-4
ISSN	1432-1106 ; 0014-4819
ISSN (online)	1432-1106
ISSN	0014-4819
DOI	10.1007/s00221-009-2105-x
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Zs.A 278: Show issues

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Book ; Thesis: An investigation of heat transfer to liquids boiling inside vertical tubes

Mantzouranis, Basile Georges

1958

Language	Undetermined
Document type	Book ; Thesis
Thesis / German Habilitation thesis	London, Univ., Imperial Coll., Ph.D. 1958
Note	Mikrofilm-Ausg.: 1 Mikrofilm
Database	Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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Book: Ta geōrgika biblia stēn archaia Ellada, tē Rōmē kai to Byzantio

Ganossis, Basile Georges

1949

Keywords	library science ; computer science
Language	Greek
Size	78 p.
Publishing place	Athēnai
Document type	Book
Database	NAL-Catalogue (AGRICOLA)

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Book: Dokimia kai moletai

Ganossis, Basile Georges

1936

Title translation	Experiments and studies.
Keywords	methodology ; agricultural research
Language	Greek
Size	169 p. ;, 20 cm.
Publisher	Ek toy Ēthnikoy typographeioy
Publishing place	En Athēnas
Document type	Book
Note	Experiments and studies. ; At head of title: Ypoyrgeion geōrgias. B.G. Ganōsē.
Database	NAL-Catalogue (AGRICOLA)

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