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  1. Article: How Refined Surgical Technical Solutions Can Make Bentall Operation a Low-Risk Procedure: 20-Year Personal Experience at the "Root" of the Aortic Diseases-It Is Time to Change Surgical Guidelines.

    Ruvolo, Giovanni / Altieri, Claudia / Bassano, Carlo / Buioni, Dario / Nardi, Paolo / Pisano, Calogera

    Journal of clinical medicine

    2023  Volume 12, Issue 23

    Abstract: 1) Objective: Twenty years' experience of Bentall-De Bono operations by one surgeon. (2) Methods: From January 2003 to September 2023, four-hundred-and-two patients aged 65.9 ± 15 years underwent a Bentall operation. The EuroScore-2 was 5.0% ± 3.8%. ... ...

    Abstract (1) Objective: Twenty years' experience of Bentall-De Bono operations by one surgeon. (2) Methods: From January 2003 to September 2023, four-hundred-and-two patients aged 65.9 ± 15 years underwent a Bentall operation. The EuroScore-2 was 5.0% ± 3.8%. Associated procedures were performed on 113 patients (28.1%). Results: Operative mortality was 1.2% (
    Language English
    Publishing date 2023-11-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12237330
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The Risk of Reintervention of the Trifecta Bioprosthesis.

    Nardi, Paolo / Bassano, Carlo / Ruvolo, Giovanni

    The Annals of thoracic surgery

    2021  Volume 112, Issue 2, Page(s) 683–684

    MeSH term(s) Aortic Valve/diagnostic imaging ; Aortic Valve/surgery ; Bioprosthesis/adverse effects ; Heart Valve Prosthesis/adverse effects ; Humans
    Language English
    Publishing date 2021-01-06
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 211007-6
    ISSN 1552-6259 ; 0003-4975
    ISSN (online) 1552-6259
    ISSN 0003-4975
    DOI 10.1016/j.athoracsur.2020.09.087
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Early-Staged Carotid Artery Stenting Prior to Coronary Artery Bypass Grafting: Analysis of the Early and Mid-Term Results in Comparison with a Consecutive Cohort of Isolated Coronary Artery Surgery Patients.

    Nardi, Paolo / Altieri, Claudia / Pisano, Calogera / Oddi, Fabio Massimo / Ranucci, Alessandro / Fresilli, Mauro / Salvati, Alessandro Cristian / Buioni, Dario / Scognamiglio, Mattia / Ajello, Valentina / Bassano, Carlo / Ascoli Marchetti, Andrea / Ippoliti, Arnaldo / Ruvolo, Giovanni

    Journal of clinical medicine

    2024  Volume 13, Issue 2

    Abstract: Aim: The aim of the present study was to analyze retrospectively the results of patients who underwent early-staged, i.e., within 24-48 h, carotid artery stenting (e-s CAS) before coronary artery bypass grafting (CABG).: Methods: Between December ... ...

    Abstract Aim: The aim of the present study was to analyze retrospectively the results of patients who underwent early-staged, i.e., within 24-48 h, carotid artery stenting (e-s CAS) before coronary artery bypass grafting (CABG).
    Methods: Between December 2014 and December 2022, 1046 consecutive patients underwent CABG; 31 of these patients (3%) were subjected to e-s CAS prior to CABG (e-s CAS + CABG group). Preoperative and intraoperative variables and early and mid-term results of the e-s CAS + CABG group were compared with those of patients who underwent isolated CABG (CABG group).
    Results: As compared with the CABG group, the e-s CAS + CABG group showed a worse clinical risk profile due to higher Euroscore-2 values and incidence of obstructive pulmonary disease and bilateral carotid artery and peripheral artery diseases (
    Conclusions: CABG preceded by e-s CAS appears to be associated with satisfactory early outcomes while limiting the risk of myocardial infarction to a very short time interval between the two procedures. Freedom from late all-causes death, cardiac death, and MACCEs were comparable and equally satisfactory, underscoring the positive protective effects of CAS and CABG on the carotid and coronary territories over time.
    Language English
    Publishing date 2024-01-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13020480
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  4. Article: The role of the female gender on mid-term outcome after coronary artery bypass grafting: a retrospective study.

    Nardi, Paolo / Pisano, Calogera / Bassano, Carlo / Bertoldo, Fabio / Buioni, Dario / Labriola, Vincenzo / Salvati, Alessandro Cristian / Scognamiglio, Mattia / Altieri, Claudia / Ruvolo, Giovanni

    Journal of thoracic disease

    2024  Volume 16, Issue 2, Page(s) 862–874

    Abstract: Background: Data on female gender differences on clinical prognosis after coronary artery bypass grafting (CABG) are still controversial. We evaluated retrospectively the impact of women patients in comparison with men undergoing CABG on mid-term ... ...

    Abstract Background: Data on female gender differences on clinical prognosis after coronary artery bypass grafting (CABG) are still controversial. We evaluated retrospectively the impact of women patients in comparison with men undergoing CABG on mid-term outcome.
    Methods: Between December 2014 and March 2022, 1,044 consecutive patients (162 females, 15.5%, 882 males, 84.5%) underwent isolated CABG. The mean follow-up was 40±27 (median 38) months. Logistic and Cox model analysis regressions were used to assess the risk of female gender and other variables, Kaplan-Meier estimates to assess survival rates.
    Results: Women did not have a significant higher operative mortality than men (3.09%
    Conclusions: Women undergoing CABG with the same surgical techniques currently adopted for men, do not appear to be associated with worse early prognosis. Freedom from late all-causes mortality, cardiac death and adverse cardiac events are comparable and equally satisfactory, highlighting the positive protective effect of CABG over time also in women.
    Language English
    Publishing date 2024-02-04
    Publishing country China
    Document type Journal Article
    ZDB-ID 2573571-8
    ISSN 2077-6624 ; 2072-1439
    ISSN (online) 2077-6624
    ISSN 2072-1439
    DOI 10.21037/jtd-23-932
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  5. Article: Surgical "elephant trunk" arch replacement with a branched arch prosthesis: two alternative operative techniques.

    Bassano, Carlo / Buioni, Dario / Scafuri, Antonio / Nardi, Paolo / Pisano, Calogera / Bertoldo, Fabio / Ruvolo, Giovanni

    Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery

    2021  Volume 18, Issue 2, Page(s) 67–70

    Abstract: Introduction: Elephant trunk repair of the aortic arch cannot be performed with a branched prosthesis.: Aim: We conceived two different modifications of the original technique to perform an arch replacement with a branched graft, while arranging an ... ...

    Abstract Introduction: Elephant trunk repair of the aortic arch cannot be performed with a branched prosthesis.
    Aim: We conceived two different modifications of the original technique to perform an arch replacement with a branched graft, while arranging an adequate landing zone for a subsequent thoracic endovascular aortic repair, without the need of dedicated material.
    Material and methods: Eight consecutive patients underwent arch replacement with one of our techniques. Five were emergency patients with acute aortic dissection, and 3 suffered chronic expansive disease. The "modified elephant trunk" includes a separate anastomosis of an endo-luminal prosthetic segment in the descending aorta. Subsequently, the branched arch prosthesis is anastomosed to the distal aortic stump with the attached trunk. In the "prophylactic debranching", a tail is left on the distal end of the arch prosthesis, so that the branches for the supra-aortic vessels will remain displaced proximally, allowing a "zone 1" available for landing.
    Results: Three patients experienced transient cerebral deficits (1 transient ischemic attack and post-operative delirium in 2 cases), 1 required re-operation for bleeding and 2 needed prolonged intubation. One died of multi-organ failure.
    Conclusions: Both techniques proved to be easily reproducible, and allow an adequate landing zone for a subsequent endovascular procedure, while retaining the advantages of using a tetra-furcated prosthesis. They are a viable alternative when a hybrid prosthesis cannot be implanted.
    Language English
    Publishing date 2021-07-05
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 2237053-5
    ISSN 1897-4252 ; 1731-5530
    ISSN (online) 1897-4252
    ISSN 1731-5530
    DOI 10.5114/kitp.2021.107465
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  6. Article ; Online: PAS-Port in Coronary Artery Bypass Grafting.

    Bassano, Carlo / Bovio, Emanuele / Nardi, Paolo / Ruvolo, Giovanni

    The Annals of thoracic surgery

    2018  Volume 105, Issue 1, Page(s) 334

    MeSH term(s) Coronary Artery Bypass ; Coronary Artery Bypass, Off-Pump
    Language English
    Publishing date 2018
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 211007-6
    ISSN 1552-6259 ; 0003-4975
    ISSN (online) 1552-6259
    ISSN 0003-4975
    DOI 10.1016/j.athoracsur.2017.03.060
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  7. Article ; Online: Early structural valve deterioration of the Mitroflow biological valve prosthesis.

    Nardi, Paolo / Bassano, Carlo / Pellegrino, Antonio / Ruvolo, Giovanni

    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

    2018  Volume 54, Issue 1, Page(s) 200–201

    MeSH term(s) Aortic Valve ; Bioprosthesis ; Heart Valve Prosthesis
    Language English
    Publishing date 2018-04-04
    Publishing country Germany
    Document type Letter ; Comment
    ZDB-ID 639293-3
    ISSN 1873-734X ; 1010-7940 ; 1567-4258
    ISSN (online) 1873-734X
    ISSN 1010-7940 ; 1567-4258
    DOI 10.1093/ejcts/ezy136
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  8. Article ; Online: Devices for a clampless approach to coronary artery operations: effect on stroke rate.

    Bassano, Carlo / Bovio, Emanuele

    The Annals of thoracic surgery

    2015  Volume 99, Issue 5, Page(s) 1867–1868

    MeSH term(s) Aortic Diseases/complications ; Atherosclerosis/complications ; Coronary Artery Bypass/adverse effects ; Female ; Humans ; Male ; Postoperative Complications/epidemiology ; Stroke/epidemiology
    Language English
    Publishing date 2015-05
    Publishing country Netherlands
    Document type Comment ; Letter
    ZDB-ID 211007-6
    ISSN 1552-6259 ; 0003-4975
    ISSN (online) 1552-6259
    ISSN 0003-4975
    DOI 10.1016/j.athoracsur.2014.07.033
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  9. Article ; Online: Long-Term Follow-Up of Device-Assisted Clampless Off-Pump Coronary Artery Bypass Grafting Compared with Conventional On-Pump Technique.

    Bassano, Carlo / Nardi, Paolo / Buioni, Dario / Asta, Laura / Pisano, Calogera / Bertoldo, Fabio / Altieri, Claudia / Ruvolo, Giovanni

    International journal of environmental research and public health

    2021  Volume 19, Issue 1

    Abstract: Study objective: To evaluate the long-term outcomes of clampless off-pump coronary artery bypass grafting (C-OPCAB) compared with conventional on-pump double clamping coronary artery bypass grafting (C-CABG).: Methods: From October 2006 to December ... ...

    Abstract Study objective: To evaluate the long-term outcomes of clampless off-pump coronary artery bypass grafting (C-OPCAB) compared with conventional on-pump double clamping coronary artery bypass grafting (C-CABG).
    Methods: From October 2006 to December 2011, 366 patients underwent isolated coronary artery bypass grafting. After propensity score matching of preoperative variables, 143 pairs were selected who received C-OPCAB with the use of device-assisted PAS-Port proximal venous graft anastomoses or C-CABG, performed by the same surgeon experienced in both techniques. Data of the two groups of patients were retrospectively analyzed up to 14 years of follow-up.
    Results: As compared with C-OPCAB, in the C-CABG patients, the performed number of grafts per patient was higher (2.9 ± 0.5 vs. 2.6 ± 0.6,
    Conclusions: Our single-center study analysis suggests that clampless OPCAB using device-assisted proximal anastomoses proved to be not inferior to double-clamping CABG in the long-term follow-up, provided that involved surgeons are familiar with both techniques. These conclusions are supported by a large and long-term follow-up period, eliminating potential bias, i.e., by means of the propensity score matching and analyzing single-surgeon experience.
    MeSH term(s) Coronary Artery Bypass ; Follow-Up Studies ; Hospital Mortality ; Humans ; Retrospective Studies ; Stroke Volume ; Treatment Outcome ; Ventricular Function, Left
    Language English
    Publishing date 2021-12-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph19010275
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  10. Article ; Online: Circulating Levels of Ferritin, RDW, PTLs as Predictive Biomarkers of Postoperative Atrial Fibrillation Risk after Cardiac Surgery in Extracorporeal Circulation.

    Altieri, Claudia / Pisano, Calogera / Vincenzo, Labriola / Ferrante, Maria Sabrina / Pellerito, Valentina / Nardi, Paolo / Bassano, Carlo / Buioni, Dario / Greco, Ernesto / Ruvolo, Giovanni / Balistreri, Carmela Rita

    International journal of molecular sciences

    2022  Volume 23, Issue 23

    Abstract: Postoperative atrial fibrillation (POAF) is the most common arrhythmia after cardiac surgery in conventional extracorporeal circulation (CECC), with an incidence of 15-50%. The POAF pathophysiology is not known, and no blood biomarkers exist. However, an ...

    Abstract Postoperative atrial fibrillation (POAF) is the most common arrhythmia after cardiac surgery in conventional extracorporeal circulation (CECC), with an incidence of 15-50%. The POAF pathophysiology is not known, and no blood biomarkers exist. However, an association between increased ferritin levels and increased AF risk, has been demonstrated. Based on such evidence, here, we evaluated the effectiveness of ferritin and other haematological parameters as POAF risk biomarkers in patients subjected to cardiac surgery. We enrolled 105 patients (mean age = 70.1 ± 7.1 years; 70 men and 35 females) with diverse heart pathologies and who were subjected to cardiothoracic surgery. Their blood samples were collected and used to determine hematological parameters. Electrocardiographic and echocardiographic parameters were also evaluated. The data obtained demonstrated significantly higher levels of serum ferritin, red cell distribution width (RDW), and platelets (PLTs) in POAF patients. However, the serum ferritin resulted to be the independent factor associated with the onset POAF risk. Thus, we detected the ferritin cut-off value, which, when ≥148.5 ng/mL, identifies the subjects at the highest POAF risk, and with abnormal ECG atrial parameters, such as PW indices, and altered structural heart disease variables. Serum ferritin, RDW, and PTLs represent predictive biomarkers of POAF after cardiothoracic surgery in CECC; particularly, serum ferritin combined with anormal PW indices and structural heart disease variables can represent an optimal tool for predicting not only POAF, but also the eventual stroke onset.
    MeSH term(s) Male ; Female ; Humans ; Middle Aged ; Aged ; Atrial Fibrillation/diagnosis ; Atrial Fibrillation/etiology ; Atrial Fibrillation/epidemiology ; Erythrocyte Indices ; Ferritins ; Risk Factors ; Postoperative Complications/diagnosis ; Postoperative Complications/etiology ; Cardiac Surgical Procedures/adverse effects ; Biomarkers ; Extracorporeal Circulation/adverse effects
    Chemical Substances Ferritins (9007-73-2) ; Biomarkers
    Language English
    Publishing date 2022-11-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms232314800
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