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Article ; Online: Declining experience with open aortic repair over time: When does too few become too risky?

Bath, Jonathan

2024 Volume 79, Issue 2, Page(s) 250

MeSH term(s)	Humans ; Aortic Aneurysm, Thoracic ; Aorta
Language	English
Publishing date	2024-01-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	605700-7
ISSN	1097-6809 ; 0741-5214
ISSN (online)	1097-6809
ISSN	0741-5214
DOI	10.1016/j.jvs.2023.09.029
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Article: How I do it: Established and novel methods for left subclavian revascularization with thoracic endovascular aortic repair.

Huffman, Jen / Bath, Jonathan

Journal of vascular surgery cases and innovative techniques

2023 Volume 10, Issue 2, Page(s) 101367

Abstract: Left subclavian artery revascularization at the time of thoracic endovascular aortic repair has been the subject of discussion for over a decade. Contemporary viewpoints suggest that revascularization should be performed where possible to decrease the ... ...

Abstract	Left subclavian artery revascularization at the time of thoracic endovascular aortic repair has been the subject of discussion for over a decade. Contemporary viewpoints suggest that revascularization should be performed where possible to decrease the risk of perioperative stroke, spinal cord ischemia, and, to a lesser degree, loss of upper extremity function. In this article, we present traditional methods as well as descriptions of newer options and technology for preservation of left subclavian artery flow during thoracic endovascular aortic repair.
Language	English
Publishing date	2023-12-20
Publishing country	United States
Document type	Journal Article
ISSN	2468-4287
ISSN	2468-4287
DOI	10.1016/j.jvscit.2023.101367
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Article ; Online: Reconfigurable self-assembled DNA devices.

Benson, Erik / Bath, Jonathan

Science robotics

2023 Volume 8, Issue 77, Page(s) eadh8148

Abstract: Modular reconfigurable systems can be achieved with DNA origami, demonstrating the potential to generate molecular robots. ...

Abstract	Modular reconfigurable systems can be achieved with DNA origami, demonstrating the potential to generate molecular robots.
MeSH term(s)	Robotics ; DNA
Chemical Substances	DNA (9007-49-2)
Language	English
Publishing date	2023-04-26
Publishing country	United States
Document type	Journal Article ; Review ; Comment
ISSN	2470-9476
ISSN (online)	2470-9476
DOI	10.1126/scirobotics.adh8148
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Article ; Online: Management of Aberrant Subclavian Artery Disease in the Contemporary Era: Is It Time to Find a Common Treatment For a Rare Disorder?

D'Oria, Mario / Bath, Jonathan

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery

2022 Volume 63, Issue 5, Page(s) 768

MeSH term(s)	Cardiovascular Abnormalities/surgery ; Humans ; Subclavian Artery/abnormalities ; Subclavian Artery/diagnostic imaging ; Subclavian Artery/surgery
Language	English
Publishing date	2022-02-08
Publishing country	England
Document type	Journal Article ; Comment
ZDB-ID	1225869-6
ISSN	1532-2165 ; 1078-5884
ISSN (online)	1532-2165
ISSN	1078-5884
DOI	10.1016/j.ejvs.2021.12.021
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Zs.A 2283: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 381: Show issues

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Article ; Online: Thrombosis or vasospasm: The utility of intraoperative neuromonitoring during TCAR.

Intagliata, Alexander / Rountree, Kaitlyn / Bath, Jonathan

Vascular

2022 Volume 31, Issue 4, Page(s) 694–698

Abstract: Objectives: Transcarotid artery revascularization (TCAR) has become more prevalent as a treatment modality for carotid stenosis. Many centers perform TCAR without any adjunctive neuromonitoring, for example, somatosensory-evoked potential (SSEP) and ... ...

Abstract	Objectives: Transcarotid artery revascularization (TCAR) has become more prevalent as a treatment modality for carotid stenosis. Many centers perform TCAR without any adjunctive neuromonitoring, for example, somatosensory-evoked potential (SSEP) and electroencephalogram (EEG). Methods: We present a case of transcarotid artery revascularization (TCAR) performed with concomitant somatosensory-evoked potential (SSEP) and electroencephalogram (EEG) neuromonitoring in the setting of concerning intraoperative angiographic images. Results: TCAR was undertaken for a 58 year-old man presenting with symptomatic left carotid stenosis and right ICA occlusion. Based on his comorbidities, pre-existing conditions, and the need for dual antiplatelet therapy, TCAR was offered as an alternative to standard carotid endarterectomy. Intraoperatively, following stent delivery, no flow was appreciated through the carotid stent or distal ICA. Neuromonitoring remained stable and was reassuring for distal ICA spasm with no-reflow phenomenon. The patient tolerated the procedure well and has had no stent-related complications through 10 months of follow-up. Conclusion: This case highlights the utility of neuromonitoring with TCAR as an adjunct to intraoperative decision-making in the setting of suspected internal carotid artery (ICA) vasospasm versus thrombosis after stent delivery.
MeSH term(s)	Male ; Humans ; Middle Aged ; Carotid Stenosis/complications ; Carotid Stenosis/diagnostic imaging ; Carotid Stenosis/surgery ; Stroke/etiology ; Endovascular Procedures/adverse effects ; Risk Factors ; Treatment Outcome ; Carotid Artery Diseases/surgery ; Endarterectomy, Carotid/adverse effects ; Arteries ; Thrombosis ; Stents/adverse effects ; Retrospective Studies
Language	English
Publishing date	2022-02-28
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	2137151-9
ISSN	1708-539X ; 1708-5381
ISSN (online)	1708-539X
ISSN	1708-5381
DOI	10.1177/17085381221080002
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Zs.A 4277: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 590: Show issues

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Article ; Online: A DNA molecular printer capable of programmable positioning and patterning in two dimensions.

Benson, Erik / Marzo, Rafael Carrascosa / Bath, Jonathan / Turberfield, Andrew J

Science robotics

2022 Volume 7, Issue 65, Page(s) eabn5459

Abstract: Nanoscale manipulation and patterning usually require costly and sensitive top-down techniques such as those used in scanning probe microscopies or in semiconductor lithography. DNA nanotechnology enables exploration of bottom-up fabrication and has ... ...

Abstract	Nanoscale manipulation and patterning usually require costly and sensitive top-down techniques such as those used in scanning probe microscopies or in semiconductor lithography. DNA nanotechnology enables exploration of bottom-up fabrication and has previously been used to design self-assembling components capable of linear and rotary motion. In this work, we combine three independently controllable DNA origami linear actuators to create a nanoscale robotic printer. The two-axis positioning mechanism comprises a moveable gantry, running on parallel rails, threading a mobile sleeve. We show that the device is capable of reversibly positioning a write head over a canvas through the addition of signaling oligonucleotides. We demonstrate "write" functionality by using the head to catalyze a local DNA strand-exchange reaction, selectively modifying pixels on a canvas. This work demonstrates the power of DNA nanotechnology for creating nanoscale robotic components and could find application in surface manufacturing, biophysical studies, and templated chemistry.
MeSH term(s)	DNA/chemistry ; Nanotechnology/methods ; Nucleic Acid Conformation ; Oligonucleotides ; Printing
Chemical Substances	Oligonucleotides ; DNA (9007-49-2)
Language	English
Publishing date	2022-04-20
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
ISSN	2470-9476
ISSN (online)	2470-9476
DOI	10.1126/scirobotics.abn5459
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Article ; Online: Progression of Changes in Vascular Surgery Practices during the Novel Corona Virus SARS-CoV-2 Pandemic.

Bath, Jonathan / Aziz, Faisal / Smeds, Matthew R

Annals of vascular surgery

2021 Volume 76, Page(s) 1–9

Abstract: Introduction: The novel coronavirus SARS-CoV-2 (COVID-19) has spread rapidly since it was identified. We sought to understand its effects on vascular surgery practices stratified by VASCON surgical readiness level and determine how these effects have ... ...

Abstract	Introduction: The novel coronavirus SARS-CoV-2 (COVID-19) has spread rapidly since it was identified. We sought to understand its effects on vascular surgery practices stratified by VASCON surgical readiness level and determine how these effects have changed during the course of the pandemic. Methods: All members of the Vascular and Endovascular Surgery Society were sent electronic surveys questioning the effects of COVID-19 on their practices in the early pandemic in April (EP) and four months later in the pandemic in August (LP) 2020. Results: Response rates were 206/731 (28%) in the EP group and 108/731 (15%) in the LP group (P < 0.0001). Most EP respondents reported VASCON levels less than 3 (168/206,82%), indicating increased hospital limitations while 6/108 (6%) in the LP group reported this level (P < 0.0001). The EP group was more likely to report a lower VASCON level (increased resource limitations), and decreased clinic, hospital and emergency room consults. Despite an increase of average cases/week to pre-COVID-19 levels, 46/108 (43%) of LP report continued decreased compensation, with 57% reporting more than 10% decrease. Respondents in the decreased compensation group were more likely to have reported a VASCON level 3 or lower earlier in the pandemic (P = 0.018). 91/108(84%) of LP group have treated COVID-19 patients for thromboembolic events, most commonly acute limb ischemia (76/108) and acute DVT (76/108). While the majority of respondents are no longer delaying the vascular surgery cases, 76/108 (70%) feel that vascular patient care has suffered due to earlier delays, and 36/108 (33%) report a backlog of cases caused by the pandemic. Conclusions: COVID-19 had a profound effect on vascular surgery practices earlier in the pandemic, resulting in continued detrimental effects on the provision of vascular care as well as compensation received by vascular surgeons.
MeSH term(s)	Adult ; COVID-19 ; Delivery of Health Care/economics ; Delivery of Health Care/trends ; Fee-for-Service Plans/trends ; Female ; Health Care Surveys ; Humans ; Income/trends ; Male ; Middle Aged ; Practice Patterns, Physicians'/economics ; Practice Patterns, Physicians'/trends ; Quality Indicators, Health Care/trends ; Surgeons/economics ; Surgeons/trends ; Time Factors ; Vascular Surgical Procedures/adverse effects ; Vascular Surgical Procedures/economics ; Vascular Surgical Procedures/trends
Language	English
Publishing date	2021-04-06
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1027366-9
ISSN	1615-5947 ; 0890-5096
ISSN (online)	1615-5947
ISSN	0890-5096
DOI	10.1016/j.avsg.2021.03.002
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Zs.A 2882: Show issues

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Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

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Article: Current Hybrid Interventions in Vascular Surgery: Merging Past and Present.

Huffman, Jennifer / Nichols, W Kirt / Bath, Jonathan

Missouri medicine

2021 Volume 118, Issue 4, Page(s) 381–386

Abstract: As the United States population continues to age, the prevalence of vascular disease continues to increase and thus the role of vascular surgeons in disease intervention has become more important than ever. Over the last 30 years, endovascular techniques ...

Abstract	As the United States population continues to age, the prevalence of vascular disease continues to increase and thus the role of vascular surgeons in disease intervention has become more important than ever. Over the last 30 years, endovascular techniques have become the mainstay for management of vascular disease. However, open operations continue to play a role in management of complex vascular disease. This article provides an update and discussed the role of hybrid interventions in vascular surgery with a focus on its use in femoral endarterectomy and peripheral stenting, retrograde open mesenteric stenting.
MeSH term(s)	Endarterectomy ; Endovascular Procedures ; Humans ; Stents ; Treatment Outcome ; United States/epidemiology
Language	English
Publishing date	2021-08-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	427362-x
ISSN	0026-6620
ISSN	0026-6620
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Zs.B 182: Show issues

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Article ; Online: A Systematic Review of Contemporary Outcomes from Aortic Arch In Situ Laser Fenestration During Thoracic Endovascular Aortic Repair.

Tish, Shahed / Chase, Jo-Ana / Scoville, Caryn / Vogel, Todd R / Cheung, Steven / Bath, Jonathan

Annals of vascular surgery

2023 Volume 91, Page(s) 266–274

Abstract: Background: In situ laser fenestrated endovascular aortic repair (L-FEVAR) is a novel and creative solution for complex aortic pathologies in the urgent and emergency setting. Outcomes of this technique, however, are poorly reported. We sought to ... ...

Abstract	Background: In situ laser fenestrated endovascular aortic repair (L-FEVAR) is a novel and creative solution for complex aortic pathologies in the urgent and emergency setting. Outcomes of this technique, however, are poorly reported. We sought to evaluate the efficacy, safety, and outcomes of L-FEVAR in aortic arch pathologies. Methods: A systematic literature review and analysis were conducted in accordance with the preferred reporting items for systematic reviews and meta-analyses and Cochrane guidelines. A search was conducted using Google, PubMed, and Scopus to identify studies evaluating L-FEVAR. Two independent reviewers determined study inclusion. Case reports and series including < 10 patients were excluded. Reviewers also assessed the methodological quality and extracted data regarding outcomes. A meta-analysis of endoleak event rates was conducted using a fixed-effect model due to small sample size. Results: Eight studies met inclusion criteria between 2013 and 2021. Most studies were retrospective (87.5%) with median follow-up duration of 12.5 months (range 10-42). There were 440 patients included (range 15-148), mostly men (64%). Mean age was 61 years (range 53-68). Included patients were all symptomatic with L-FEVAR being technically successful in 93.3% of cases. The main indication for aortic arch intervention was aortic dissection. Single fenestrations occurred most frequently (68%), followed by triple (22%) then double fenestrations (9%). Meta-analysis of 8 studies (n = 440) demonstrated an endoleak event rate of 0.06 (95% confidence interval 0.04-0.09, P < 0.001) with no observed statistically significant heterogeneity of effects (Q = 7.91, P = 0.34). The median operative time was 162 min (range 53-252) with median length of stay of 10 days (range 7-17). Primary branch patency was 96.6%. Secondary patency rate was 97%. Pooled complication rates such as endoleak occurred in 4.8%, stroke in 2.0%, spinal cord ischemia in 0.2%, retrograde dissection in 0.9%, and 30-day death in 2.0%. Access complications occurred in 0.4%. Antiplatelet regimen was poorly reported in the study cohort. Conclusions: In situ laser fenestration is a feasible, safe, and effective approach to treat aortic arch disease in patients who are unsuitable for open or custom-made endovascular means. High technical success and excellent short-term branch patency can be achieved. These single-institution series exhibit promising short-term outcomes. In a similar paradigm to investigational device exemptions studies for custom-made and physician modified endografts, these preliminary data make a persuasive argument for larger long-term multi-institutional prospective study of this promising technique.
MeSH term(s)	Aged ; Female ; Humans ; Male ; Middle Aged ; Aortic Aneurysm, Thoracic/diagnostic imaging ; Aortic Aneurysm, Thoracic/surgery ; Aortic Aneurysm, Thoracic/complications ; Aortic Diseases/surgery ; Blood Vessel Prosthesis/adverse effects ; Blood Vessel Prosthesis Implantation/adverse effects ; Endoleak/etiology ; Endoleak/surgery ; Endovascular Aneurysm Repair ; Endovascular Procedures ; Lasers ; Prospective Studies ; Prosthesis Design ; Retrospective Studies ; Risk Factors ; Treatment Outcome
Language	English
Publishing date	2023-01-12
Publishing country	Netherlands
Document type	Journal Article ; Review ; Systematic Review
ZDB-ID	1027366-9
ISSN	1615-5947 ; 0890-5096
ISSN (online)	1615-5947
ISSN	0890-5096
DOI	10.1016/j.avsg.2023.01.009
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Zs.A 2882: Show issues

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ab Jg. 2022: Lesesaal (EG)

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Article: Left carotid chimney and left subclavian artery laser fenestration for zone 1 thoracic endovascular aortic repair.

Huffman, Jen / McSpadden, Madeleine / Buelter, Joseph / Vogel, Todd / Bath, Jonathan

Journal of vascular surgery cases and innovative techniques

2023 Volume 9, Issue 3, Page(s) 101283

Abstract: Thoracic endovascular aortic repair has become an increasingly used option for treatment of descending thoracic aortic aneurysms and dissections. Pathology involving the proximal thoracic aorta is more complex and requires revascularization of the ... ...

Abstract	Thoracic endovascular aortic repair has become an increasingly used option for treatment of descending thoracic aortic aneurysms and dissections. Pathology involving the proximal thoracic aorta is more complex and requires revascularization of the subclavian and carotid arteries. We report a case of an arch thoracic aortic pseudoaneurysm repaired via a complete endovascular approach using a left carotid chimney and left subclavian artery laser fenestration.
Language	English
Publishing date	2023-08-02
Publishing country	United States
Document type	Case Reports
ISSN	2468-4287
ISSN	2468-4287
DOI	10.1016/j.jvscit.2023.101283
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