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  1. Article: Detección de portadores de Vibrio cholerae convalecientes mediante el enterotest.

    Grados, P / Battilana, C

    Boletin de la Oficina Sanitaria Panamericana. Pan American Sanitary Bureau

    1994  Volume 116, Issue 4, Page(s) 285–289

    Abstract: Although the existence of chronic carriers of Vibrio cholerae has been posited, the information in this regard is limited and contradictory. In order to determine the usefulness of the encapsulated string test (enterotest) for detecting V. cholerae in ... ...

    Title translation Detection of convalescent Vibrio cholerae carriers using the enterotest.
    Abstract Although the existence of chronic carriers of Vibrio cholerae has been posited, the information in this regard is limited and contradictory. In order to determine the usefulness of the encapsulated string test (enterotest) for detecting V. cholerae in duodenal secretions of biliary origin (biliduodenal secretions), 59 patients (30 males and 29 females) over the age of 15 with clinically and bacteriologically diagnosed cholera were evaluated. All the patients, who were treated at the María Auxiliadora Departmental Hospital in Lima, Peru, were put on the same rehydration regimen and were given 2 g of tetracycline daily for 3 days. Between 24 h and 7 days after completion of the antibiotic treatment the first control tests were performed: culture of biliduodenal secretions obtained using enterotest and culture of feces obtained by rectal swab. No patient had diarrhea at the time of the first test. The biliduodenal secretion cultures revealed the presence of V. cholerae in five patients (8.5%) (four females and one male), while the fecal culture yielded negative results in all cases. One week later the control test was repeated on four of the five patients. All the biliduodenal secretion cultures were negative and only one fecal culture was positive at this stage. The patient in question was subjected to the same control tests one week later and both were negative. It is concluded that enterotest can be a simple, well-tolerated, low-cost method for detecting V. cholerae carriers.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Bacteriological Techniques ; Carrier State/diagnosis ; Carrier State/microbiology ; Cholera/diagnosis ; Cholera/drug therapy ; Cholera/microbiology ; Convalescence ; Feces/microbiology ; Female ; Gastrointestinal Contents/microbiology ; Humans ; Male ; Middle Aged ; Tetracycline/therapeutic use ; Vibrio cholerae/isolation & purification
    Chemical Substances Tetracycline (F8VB5M810T)
    Language Spanish
    Publishing date 1994-04
    Publishing country United States
    Document type English Abstract ; Journal Article
    ZDB-ID 40508-5
    ISSN 0030-0632 ; 0085-4638 ; 0366-1695
    ISSN 0030-0632 ; 0085-4638 ; 0366-1695
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Online: The Analytical Method algorithm for trigger primitives generation at the LHC Drift Tubes detector

    Abbiendi, G. / Maestre, J. Alcaraz / Fernández, A. Álvarez / González, B. Álvarez / Amapane, N. / Bachiller, I. / Barcellan, L. / Baldanza, C. / Battilana, C. / Bellato, M. / Bencze, G. / Benettoni, M. / Beni, N. / Benvenuti, A. / Bergnoli, A. / Ramos, L. C. Blanco / Borgonovi, L. / Bragagnolo, A. / Cafaro, V. /
    Calderon, A. / Calvo, E. / Carlin, R. / Montoya, C. A. Carrillo / Cavallo, F. R. / Ruiz, J. M. Cela / Cepeda, M. / Cerrada, M. / Checchia, P. / Ciano, L. / Colino, N. / Corti, D. / Cotto, G. / Crupano, A. / Calzada, S. Cuadrado / Cuevas, J. / Cuffiani, M. / Dallavalle, G. M. / Dattola, D. / De La Cruz, B. / Rodríguez, C. I. de Lara / De Remigis, P. / Cid, C. Erice / Eliseev, D. / Fabbri, F. / Fanfani, A. / Fasanella, D. / Bedoya, C. F. / de Trocóniz, J. F. / del Val, D. Fernández / Menéndez, J. Fernández

    2023  

    Abstract: The Compact Muon Solenoid (CMS) experiment prepares its Phase-2 upgrade for the high-luminosity era of the LHC operation (HL-LHC). Due to the increase of occupancy, trigger latency and rates, the full electronics of the CMS Drift Tube (DT) chambers will ... ...

    Abstract The Compact Muon Solenoid (CMS) experiment prepares its Phase-2 upgrade for the high-luminosity era of the LHC operation (HL-LHC). Due to the increase of occupancy, trigger latency and rates, the full electronics of the CMS Drift Tube (DT) chambers will need to be replaced. In the new design, the time bin for the digitisation of the chamber signals will be of around 1~ns, and the totality of the signals will be forwarded asynchronously to the service cavern at full resolution. The new backend system will be in charge of building the trigger primitives of each chamber. These trigger primitives contain the information at chamber level about the muon candidates position, direction, and collision time, and are used as input in the L1 CMS trigger. The added functionalities will improve the robustness of the system against ageing. An algorithm based on analytical solutions for reconstructing the DT trigger primitives, called Analytical Method, has been implemented both as a software C++ emulator and in firmware. Its performance has been estimated using the software emulator with simulated and real data samples, and through hardware implementation tests. Measured efficiencies are 96 to 98\% for all qualities and time and spatial resolutions are close to the ultimate performance of the DT chambers. A prototype chain of the HL-LHC electronics using the Analytical Method for trigger primitive generation has been installed during Long Shutdown 2 of the LHC and operated in CMS cosmic data taking campaigns in 2020 and 2021. Results from this validation step, the so-called Slice Test, are presented.

    Comment: 16 pages, 11 figures
    Keywords High Energy Physics - Experiment ; Physics - Instrumentation and Detectors
    Subject code 621
    Publishing date 2023-02-03
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Comparative effectiveness of co-trimoxazole and tetracycline in the treatment of Cholera.

    Grados, P / Bravo, N / Battilana, C

    Bulletin of the Pan American Health Organization

    1996  Volume 30, Issue 1, Page(s) 36–42

    Abstract: The purpose of the study reported here was to compare the bactericidal effectiveness of tetracycline and co-trimoxazole (a combination of sulfamethoxazole and trimethoprim) in treating cholera. The study, an open-ended random trial using adult patients ... ...

    Abstract The purpose of the study reported here was to compare the bactericidal effectiveness of tetracycline and co-trimoxazole (a combination of sulfamethoxazole and trimethoprim) in treating cholera. The study, an open-ended random trial using adult patients with cholera cases confirmed by stool culture, was carried out in March 1993 at the Cholera Treatment Unit (CTU) of the Hospital de Apoyo Departmental María Auxiliadora in Lima, Peru. A total of 107 subjects were divided into two groups (A and B). The 50 in Group A received 500 mg of tetracycline orally every 6 hours for 3 days; the 57 in Group B received co-trimoxazole (160 mg of trimethoprim and 800 mg of sulfamethoxazole) orally every 12 hours for 3 days. The two groups were comparable in terms of age, sex, duration of symptoms prior to hospital admission, time at which antibiotic treatment was initiated, and clinical evolution. Control stool cultures of specimens obtained after treatment showed Vibrio cholerae O-1 present in 2% of the Group A and 12.3% of the Group B patients, and also showed V. cholerae non-O-1 present in 2% of the Group A patients and 3.5% of the Group B patients. Overall, it was concluded that both therapeutic treatment regimens were effective and that the strains of V. cholerae observed in the southern sector of the city of Lima were still susceptible to both antibiotics.
    MeSH term(s) Adolescent ; Adult ; Anti-Bacterial Agents/therapeutic use ; Cholera/drug therapy ; Cholera/microbiology ; Drug Therapy, Combination ; Female ; Humans ; Male ; Middle Aged ; Prospective Studies ; Single-Blind Method ; Tetracycline/therapeutic use ; Tetracycline Resistance ; Trimethoprim, Sulfamethoxazole Drug Combination/therapeutic use
    Chemical Substances Anti-Bacterial Agents ; Trimethoprim, Sulfamethoxazole Drug Combination (8064-90-2) ; Tetracycline (F8VB5M810T)
    Language English
    Publishing date 1996-03
    Publishing country United States
    Document type Clinical Trial ; Comparative Study ; Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 441844-x
    ISSN 0085-4638
    ISSN 0085-4638
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Observation of Collider Muon Neutrinos with the SND@LHC Experiment.

    Albanese, R / Alexandrov, A / Alicante, F / Anokhina, A / Asada, T / Battilana, C / Bay, A / Betancourt, C / Biswas, R / Blanco Castro, A / Bogomilov, M / Bonacorsi, D / Bonivento, W M / Bordalo, P / Boyarsky, A / Buontempo, S / Campanelli, M / Camporesi, T / Canale, V /
    Castro, A / Centanni, D / Cerutti, F / Chernyavskiy, M / Choi, K-Y / Cholak, S / Cindolo, F / Climescu, M / Conaboy, A P / Dallavalle, G M / Davino, D / de Bryas, P T / De Lellis, G / De Magistris, M / De Roeck, A / De Rújula, A / De Serio, M / De Simone, D / Di Crescenzo, A / Donà, R / Durhan, O / Fabbri, F / Fedotovs, F / Ferrillo, M / Ferro-Luzzi, M / Fini, R A / Fiorillo, A / Fresa, R / Funk, W / Garay Walls, F M / Golovatiuk, A / Golutvin, A / Graverini, E / Guler, A M / Guliaeva, V / Haefeli, G J / Helo Herrera, J C / van Herwijnen, E / Iengo, P / Ilieva, S / Infantino, A / Iuliano, A / Jacobsson, R / Kamiscioglu, C / Kauniskangas, A M / Khalikov, E / Kim, S H / Kim, Y G / Klioutchnikov, G / Komatsu, M / Konovalova, N / Kovalenko, S / Kuleshov, S / Lacker, H M / Lantwin, O / Lasagni Manghi, F / Lauria, A / Lee, K Y / Lee, K S / Lo Meo, S / Loschiavo, V P / Marcellini, S / Margiotta, A / Mascellani, A / Miano, A / Mikulenko, A / Montesi, M C / Navarria, F L / Ogawa, S / Okateva, N / Ovchynnikov, M / Paggi, G / Park, B D / Pastore, A / Perrotta, A / Podgrudkov, D / Polukhina, N / Prota, A / Quercia, A / Ramos, S / Reghunath, A / Roganova, T / Ronchetti, F / Rovelli, T / Ruchayskiy, O / Ruf, T / Sabate Gilarte, M / Samoilov, M / Scalera, V / Schneider, O / Sekhniaidze, G / Serra, N / Shaposhnikov, M / Shevchenko, V / Shchedrina, T / Shchutska, L / Shibuya, H / Simone, S / Siroli, G P / Sirri, G / Soares, G / Soto Sandoval, O J / Spurio, M / Starkov, N / Timiryasov, I / Tioukov, V / Tramontano, F / Trippl, C / Ursov, E / Ustyuzhanin, A / Vankova-Kirilova, G / Verguilov, V / Viegas Guerreiro Leonardo, N / Vilela, C / Visone, C / Wanke, R / Yaman, E / Yazici, C / Yoon, C S / Zaffaroni, E / Zamora Saa, J

    Physical review letters

    2023  Volume 131, Issue 3, Page(s) 31802

    Abstract: We report the direct observation of muon neutrino interactions with the SND@LHC detector at the Large Hadron Collider. A dataset of proton-proton collisions at sqrt[s]=13.6  TeV collected by SND@LHC in 2022 is used, corresponding to an integrated ... ...

    Abstract We report the direct observation of muon neutrino interactions with the SND@LHC detector at the Large Hadron Collider. A dataset of proton-proton collisions at sqrt[s]=13.6  TeV collected by SND@LHC in 2022 is used, corresponding to an integrated luminosity of 36.8  fb^{-1}. The search is based on information from the active electronic components of the SND@LHC detector, which covers the pseudorapidity region of 7.2<η<8.4, inaccessible to the other experiments at the collider. Muon neutrino candidates are identified through their charged-current interaction topology, with a track propagating through the entire length of the muon detector. After selection cuts, 8 ν_{μ} interaction candidate events remain with an estimated background of 0.086 events, yielding a significance of about 7 standard deviations for the observed ν_{μ} signal.
    Language English
    Publishing date 2023-08-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.131.031802
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: El trataminento de la diarrea coleriforme en la gestación.

    Grados, P / Battilana, C A

    Boletin de la Oficina Sanitaria Panamericana. Pan American Sanitary Bureau

    1994  Volume 116, Issue 3, Page(s) 198–203

    Abstract: A retrospective review was conducted of the clinical histories of 43 pregnant women treated for acute diarrheal disease in the emergency ward of the María Auxiliadora Departmental Hospital (HADMA) in Lima, Peru, and 32 of the histories were selected for ... ...

    Title translation Treatment of choleriform diarrhea during pregnancy.
    Abstract A retrospective review was conducted of the clinical histories of 43 pregnant women treated for acute diarrheal disease in the emergency ward of the María Auxiliadora Departmental Hospital (HADMA) in Lima, Peru, and 32 of the histories were selected for this study. These 32 patients had been admitted to the cholera treatment unit (CTU) of the HADMA for acute choleraic diarrhea with moderate or severe dehydration. The objective was to analyze the clinical evolution of the patients, their response to isotonic rehydration therapy (0.9% saline solution), and the consequences for their pregnancies. The following variables were examined: age; trimester of pregnancy; heart rate and mean blood pressure (MBP) at admission; number of hours since last normal urination; duration of diarrhea; degree of dehydration; volume of diarrhea and vomiting; volume of saline solution administered in the first 2 hours and in total; volume of multi-electrolyte solution (MES) or oral rehydration salts (ORS) administered from the second to the sixth hour and in total; and hours between admission to the emergency ward and transfer to the cholera treatment unit (EME/CTU). Logistic regression analysis revealed a direct and statistically significant correlation between the time of recovery of diuresis and the EME/CTU (P = 0.001; r = 0.65), as well as between time of recovery of diuresis and the volume of diarrhea in the first 4 hours.(ABSTRACT TRUNCATED AT 250 WORDS)
    MeSH term(s) Acute Disease ; Adolescent ; Adult ; Cholera/complications ; Cholera/therapy ; Dehydration/etiology ; Dehydration/therapy ; Diarrhea/complications ; Diarrhea/therapy ; Female ; Fluid Therapy ; Humans ; Hypotension/etiology ; Hypotension/therapy ; Oliguria/etiology ; Oliguria/therapy ; Peru ; Pregnancy ; Pregnancy Complications, Infectious/therapy ; Pregnancy Outcome ; Regression Analysis ; Retrospective Studies ; Water-Electrolyte Imbalance/etiology ; Water-Electrolyte Imbalance/therapy
    Language Spanish
    Publishing date 1994-03
    Publishing country United States
    Document type English Abstract ; Journal Article ; Review
    ZDB-ID 40508-5
    ISSN 0030-0632 ; 0085-4638 ; 0366-1695
    ISSN 0030-0632 ; 0085-4638 ; 0366-1695
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Study of irregular anti-N antibodies in the hematies of a renal transplant patient.

    Elias, A / Padron, A / Ortiz, M / Lavalle, M / Battilana, C / Rojas, M / Koga, V / Bustamante, S

    Transplantation proceedings

    2002  Volume 34, Issue 1, Page(s) 363

    MeSH term(s) Adult ; Blood Group Incompatibility ; Humans ; Isoantibodies/blood ; Kidney Transplantation/immunology ; Male ; Phenotype ; Rh-Hr Blood-Group System/genetics
    Chemical Substances Isoantibodies ; Rh-Hr Blood-Group System
    Language English
    Publishing date 2002-02
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 82046-5
    ISSN 1873-2623 ; 0041-1345
    ISSN (online) 1873-2623
    ISSN 0041-1345
    DOI 10.1016/s0041-1345(01)02802-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book: Reflexiones sobre "Hijo de hombre" de Augusto Roa Bastos

    Battilana, Carlos

    (Publicaciones universitarias europeas : Serie 24, Lenguas y literaturas iberorománicas ; 10)

    1979  

    Author's details Carlos Battilana
    Series title Publicaciones universitarias europeas : Serie 24, Lenguas y literaturas iberorománicas ; 10
    Language Spanish
    Size 81 S
    Publisher Lang
    Publishing place Frankfurt am Main u.a.
    Document type Book
    ISBN 3820464964 ; 9783820464962
    Database Former special subject collection: coastal and deep sea fishing

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  8. Book ; Thesis: Vorarbeit zu einer kritischen Edition des calderonianischen Schauspiels "La devoción de la Misa"

    Battilana, Carlos

    (Europäische Hochschulschriften : Reihe 24 ; 7)

    1977  

    Author's details Carlos Battilana
    Series title Europäische Hochschulschriften : Reihe 24 ; 7
    Language German
    Size 190 S
    Publisher Lang
    Publishing place Frankfurt a.M
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Univ., Diss.. (Nicht f.d. Austausch)--Hamburg, 1977
    Database Former special subject collection: coastal and deep sea fishing

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  9. Article: PAH extraction and estimation of plasma flow in diseased human kidneys.

    Battilana, C / Zhang, H P / Olshen, R A / Wexler, L / Myers, B D

    The American journal of physiology

    1991  Volume 261, Issue 4 Pt 2, Page(s) F726–33

    Abstract: We have analyzed the efficiency with which p-amino-hippuric acid (PAH) is extracted (EPAH) by patients with healthy kidneys (n = 13) or kidneys damaged by chronic cyclosporin nephropathy (n = 21) or primary glomerulopathy (n = 12); respective values ( ... ...

    Abstract We have analyzed the efficiency with which p-amino-hippuric acid (PAH) is extracted (EPAH) by patients with healthy kidneys (n = 13) or kidneys damaged by chronic cyclosporin nephropathy (n = 21) or primary glomerulopathy (n = 12); respective values (mean +/- SE) for EPAH were 0.87 +/- 0.03, 0.77 +/- 0.03, and 0.69 +/- 0.04. Judged by a 131I-hippuran-to-PAH clearance ratio of 0.75 +/- 0.05, extraction ratio of hippuran was less efficient than EPAH in three glomerulopathic patients. A direct relationship was defined between EPAH and glomerular filtration rate (GFR) (r = 0.54) or calculated efferent oncotic pressure (IIE; r = 0.41, P less than 0.01). Curve fitting by means of quadratic spline functions revealed GFR and IIE to be additive in predicting EPAH (R2 = 0.45). Linear model prediction methods and a sample reuse technique failed to predict EPAH reliably from GFR and preglomerular oncotic pressure (IIA); however, 95% prediction intervals exceed 0.30 EPAH units in width. We conclude that oncotic pressure (presumably reflecting albumin concentration) along with GFR is predictive of EPAH depression in humans with chronic renal disease. However, even sophisticated curve-fitting techniques are too imprecise for accurate prediction of EPAH in a given individual. We submit that renal venous sampling to determine EPAH continues to be necessary for the accurate determination of the rate of plasma flow in the injured human kidney.
    MeSH term(s) Adolescent ; Adult ; Analysis of Variance ; Female ; Glomerular Filtration Rate ; Humans ; Iodohippuric Acid/pharmacokinetics ; Kidney/metabolism ; Kidney Diseases/metabolism ; Kidney Diseases/physiopathology ; Male ; Middle Aged ; Models, Biological ; Renal Circulation ; p-Aminohippuric Acid/pharmacokinetics
    Chemical Substances Iodohippuric Acid (147-58-0) ; p-Aminohippuric Acid (Y79XT83BJ9)
    Language English
    Publishing date 1991-10
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 2948-8
    ISSN 0002-9513
    ISSN 0002-9513
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Single-dose pharmacokinetics of ceftriaxone in patients with end-stage renal disease and hemodialysis.

    Losno Garcia, R / Santivañez, V / Battilana, C A

    Chemotherapy

    1988  Volume 34, Issue 4, Page(s) 261–266

    Abstract: We report the pharmacokinetic parameters of ceftriaxone in 11 patients on hemodialysis with end-stage renal disease (ESRD; creatinine clearance less than 5 ml/min/1.73 m2). The patients were studied during the interdialysis period and during 4 h of ... ...

    Abstract We report the pharmacokinetic parameters of ceftriaxone in 11 patients on hemodialysis with end-stage renal disease (ESRD; creatinine clearance less than 5 ml/min/1.73 m2). The patients were studied during the interdialysis period and during 4 h of hemodialysis. The mean age was 53.4 years. After the administration of 1 g of ceftriaxone during a constant intravenous infusion over a 30-min period, t 1/2 was 16.6 h, beta was 0.0418 +/- 0.0106 h-1, VD was 14.5 +/- 3.0 liters/1.73 m2 and Clp was 0.40 +/- 0.05 liters/h for the interdialysis period. Hemodialysis started 24 h after the infusion. The initial plasma ceftriaxone concentration was 68.6 +/- 10.8 micrograms/ml. This value dropped to 40.4 +/- 4.7 micrograms/ml at the end of the 4th hour, indicating a significant 41% decay in blood levels during hemodialysis (p less than 0.001). The t 1/2 decreased to 4.88 h, kel rose to 0.142 +/- 0.0250 h-1 and Clp increased to 1.73 +/- 0.44 liters/h. All values were highly significantly different (p less than 0.001) from those during the interdialysis period. The plasma ceftriaxone concentration of 40.4 +/- 4.7 micrograms/ml at the end of hemodialysis was well within the therapeutic range of the drug. We conclude that ceftriaxone has a moderated increase in t 1/2 in patients with ESRD. Ceftriaxone is significantly dialyzable, however, the plasma concentrations are in the therapeutic range by the end of a 4-hour hemodialysis, 28 h after the administration of the drug. We propose that 1 g given intravenously before each hemodialysis will be sufficient to keep the patient's plasma concentrations within the therapeutic range until the next hemodialysis.(ABSTRACT TRUNCATED AT 250 WORDS)
    MeSH term(s) Adult ; Aged ; Bacterial Infections/prevention & control ; Blood Proteins/metabolism ; Ceftriaxone/blood ; Ceftriaxone/pharmacokinetics ; Drug Administration Schedule ; Female ; Humans ; Infusions, Intra-Arterial ; Kidney Failure, Chronic/blood ; Kidney Failure, Chronic/therapy ; Male ; Middle Aged ; Protein Binding ; Renal Dialysis
    Chemical Substances Blood Proteins ; Ceftriaxone (75J73V1629)
    Language English
    Publishing date 1988
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 6708-8
    ISSN 1421-9794 ; 0009-3157
    ISSN (online) 1421-9794
    ISSN 0009-3157
    Database MEDical Literature Analysis and Retrieval System OnLINE

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