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  1. Article ; Online: Light-sensitive short hypocotyl genes confer symbiotic nodule identity in the legume Medicago truncatula.

    Lee, Tak / Orvosova, Martina / Batzenschlager, Morgane / Bueno Batista, Marcelo / Bailey, Paul C / Mohd-Radzman, Nadia A / Gurzadyan, Aram / Stuer, Naomi / Mysore, Kirankumar S / Wen, Jiangqi / Ott, Thomas / Oldroyd, Giles E D / Schiessl, Katharina

    Current biology : CB

    2024  Volume 34, Issue 4, Page(s) 825–840.e7

    Abstract: Legumes produce specialized root nodules that are distinct from lateral roots in morphology and function, with nodules intracellularly hosting nitrogen-fixing bacteria. We have previously shown that a lateral root program underpins nodule initiation, but ...

    Abstract Legumes produce specialized root nodules that are distinct from lateral roots in morphology and function, with nodules intracellularly hosting nitrogen-fixing bacteria. We have previously shown that a lateral root program underpins nodule initiation, but there must be additional developmental regulators that confer nodule identity. Here, we show two members of the LIGHT-SENSITIVE SHORT HYPOCOTYL (LSH) transcription factor family, predominantly known to define shoot meristem complexity and organ boundaries, function as regulators of nodule organ identity. In parallel to the root initiation program, LSH1/LSH2 recruit a program into the root cortex that mediates the divergence into nodules, in particular with cell divisions in the mid-cortex. This includes regulation of auxin and cytokinin, promotion of NODULE ROOT1/2 and Nuclear Factor YA1, and suppression of the lateral root program. A principal outcome of LSH1/LSH2 function is the production of cells able to accommodate nitrogen-fixing bacteria, a key feature unique to nodules.
    MeSH term(s) Medicago truncatula/genetics ; Root Nodules, Plant/genetics ; Root Nodules, Plant/microbiology ; Hypocotyl/genetics ; Hypocotyl/metabolism ; Cytokinins/genetics ; Meristem/metabolism ; Symbiosis/genetics ; Plant Proteins/genetics ; Plant Proteins/metabolism ; Gene Expression Regulation, Plant ; Plant Roots/metabolism
    Chemical Substances Cytokinins ; Plant Proteins
    Language English
    Publishing date 2024-01-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 1071731-6
    ISSN 1879-0445 ; 0960-9822
    ISSN (online) 1879-0445
    ISSN 0960-9822
    DOI 10.1016/j.cub.2024.01.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: GIP1 and GIP2 Contribute to the Maintenance of Genome Stability at the Nuclear Periphery.

    Singh, Gaurav / Batzenschlager, Morgane / Tomkova, Denisa / Herzog, Etienne / Hoffmann, Elise / Houlné, Guy / Schmit, Anne-Catherine / Berr, Alexandre / Chabouté, Marie-Edith

    Frontiers in plant science

    2022  Volume 12, Page(s) 804928

    Abstract: The maintenance of genetic information is important in eukaryotes notably through mechanisms occurring at the nuclear periphery where inner nuclear membrane proteins and nuclear pore-associated components are key factors regulating the DNA damage ... ...

    Abstract The maintenance of genetic information is important in eukaryotes notably through mechanisms occurring at the nuclear periphery where inner nuclear membrane proteins and nuclear pore-associated components are key factors regulating the DNA damage response (DDR). However, this aspect of DDR regulation is still poorly documented in plants. We addressed here how genomic stability is impaired in the
    Language English
    Publishing date 2022-01-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2613694-6
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2021.804928
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: RPG acts as a central determinant for infectosome formation and cellular polarization during intracellular rhizobial infections.

    Lace, Beatrice / Su, Chao / Invernot Perez, Daniel / Rodriguez-Franco, Marta / Vernié, Tatiana / Batzenschlager, Morgane / Egli, Sabrina / Liu, Cheng-Wu / Ott, Thomas

    eLife

    2023  Volume 12

    Abstract: Host-controlled intracellular accommodation of nitrogen-fixing bacteria is essential for the establishment of a functional Root Nodule Symbiosis (RNS). In many host plants, this occurs via transcellular tubular structures (infection threads - ITs) that ... ...

    Abstract Host-controlled intracellular accommodation of nitrogen-fixing bacteria is essential for the establishment of a functional Root Nodule Symbiosis (RNS). In many host plants, this occurs via transcellular tubular structures (infection threads - ITs) that extend across cell layers via polar tip-growth. Comparative phylogenomic studies have identified
    MeSH term(s) Rhizobium ; Symbiosis ; Nitrogen-Fixing Bacteria ; Cell Nucleus ; Cell Wall
    Language English
    Publishing date 2023-03-01
    Publishing country England
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, Non-U.S. Gov't
    ZDB-ID 2687154-3
    ISSN 2050-084X ; 2050-084X
    ISSN (online) 2050-084X
    ISSN 2050-084X
    DOI 10.7554/eLife.80741
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: MGO3 and GIP1 act synergistically for the maintenance of centromeric cohesion

    Batzenschlager, Morgane / Schmit, Anne-Catherine / Herzog, Etienne / Fuchs, Joerg / Schubert, Veit / Houlné, Guy / Chabouté, Marie-Edith

    Nucleus. 2017 Jan. 2, v. 8, no. 1

    2017  

    Abstract: The control of genomic maintenance during S phase is crucial in eukaryotes. It involves the establishment of sister chromatid cohesion, ensuring faithful chromosome segregation, as well as proper DNA replication and repair to preserve genetic information. ...

    Abstract The control of genomic maintenance during S phase is crucial in eukaryotes. It involves the establishment of sister chromatid cohesion, ensuring faithful chromosome segregation, as well as proper DNA replication and repair to preserve genetic information. In animals, nuclear periphery proteins - including inner nuclear membrane proteins and nuclear pore-associated components - are key factors which regulate DNA integrity. Corresponding functional homologues are not so well known in plants which may have developed specific mechanisms due to their sessile life. We have already characterized the Gamma-tubulin Complex Protein 3-interacting proteins (GIPs) as essential regulators of centromeric cohesion at the nuclear periphery. GIPs were also shown to interact with TSA1, first described as a partner of the epigenetic regulator MGOUN3 (MGO3)/BRUSHY1 (BRU1)/TONSOKU (TSK) involved in genomic maintenance. Here, using genetic analyses, we show that the mgo3gip1 mutants display an impaired and pleiotropic development including fasciation. We also provide evidence for the contribution of both MGO3 and GIP1 to the regulation of centromeric cohesion in Arabidopsis.
    Keywords Arabidopsis ; DNA ; DNA replication ; chromatids ; chromosome segregation ; cohesion ; epigenetics ; eukaryotic cells ; fasciation ; genomics ; interphase ; nuclear membrane ; tubulin
    Language English
    Dates of publication 2017-0102
    Size p. 98-105.
    Publishing place Taylor & Francis
    Document type Article
    ZDB-ID 2619626-8
    ISSN 1949-1042 ; 1949-1034
    ISSN (online) 1949-1042
    ISSN 1949-1034
    DOI 10.1080/19491034.2016.1276142
    Database NAL-Catalogue (AGRICOLA)

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  5. Article: Corrigendum: The GIP Gamma-Tubulin Complex-Associated Proteins are Involved in Nuclear Architecture in

    Batzenschlager, Morgane / Masoud, Kinda / Janski, Natacha / Houlné, Guy / Herzog, Etienne / Evrard, Jean-Luc / Baumberger, Nicolas / Erhardt, Mathieu / Nominé, Yves / Kieffer, Bruno / Schmit, Anne-Catherine / Chabouté, Marie-Edith

    Frontiers in plant science

    2020  Volume 11, Page(s) 589954

    Abstract: This corrects the article DOI: 10.3389/fpls.2013.00480/full.]. ...

    Abstract [This corrects the article DOI: 10.3389/fpls.2013.00480/full.].
    Language English
    Publishing date 2020-09-11
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2711035-7
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2020.589954
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Marginal band microtubules are acetylated by αTAT1.

    Ribba, Anne-Sophie / Batzenschlager, Morgane / Rabat, Clotilde / Buchou, Thierry / Moog, Sylvie / Khochbin, Saadi / Bourova-Flin, Ekaterina / Lafanechère, Laurence / Lanza, François / Sadoul, Karin

    Platelets

    2020  Volume 32, Issue 4, Page(s) 568–572

    Abstract: The discoid shape of resting platelets is maintained by a peripheral, circular bundle of microtubules called marginal band. Marginal band microtubules are acetylated on lysine 40 of the alpha-tubulin subunits. We have previously shown that the ... ...

    Abstract The discoid shape of resting platelets is maintained by a peripheral, circular bundle of microtubules called marginal band. Marginal band microtubules are acetylated on lysine 40 of the alpha-tubulin subunits. We have previously shown that the deacetylase HDAC6 is responsible for tubulin deacetylation in platelets and that the hyperacetylated state of the microtubules in
    MeSH term(s) Acetyltransferases/metabolism ; Animals ; Humans ; Mice ; Microtubules/metabolism
    Chemical Substances Acetyltransferases (EC 2.3.1.-) ; alpha-tubulin acetylase (EC 2.3.1.108)
    Language English
    Publishing date 2020-05-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 1034283-7
    ISSN 1369-1635 ; 0953-7104
    ISSN (online) 1369-1635
    ISSN 0953-7104
    DOI 10.1080/09537104.2020.1759791
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The

    Su, Chao / Klein, Marie-Luise / Hernández-Reyes, Casandra / Batzenschlager, Morgane / Ditengou, Franck Anicet / Lace, Beatrice / Keller, Jean / Delaux, Pierre-Marc / Ott, Thomas

    The Plant cell

    2020  Volume 32, Issue 5, Page(s) 1689–1702

    Abstract: The initiation of intracellular host cell colonization by symbiotic rhizobia ... ...

    Abstract The initiation of intracellular host cell colonization by symbiotic rhizobia in
    MeSH term(s) Medicago truncatula/metabolism ; Membrane Microdomains/metabolism ; Microtubules/metabolism ; Mutation/genetics ; Plant Proteins/metabolism ; Plant Root Nodulation/physiology ; Protein Binding ; Rhizobium/physiology ; Symbiosis
    Chemical Substances Plant Proteins
    Language English
    Publishing date 2020-02-25
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 623171-8
    ISSN 1532-298X ; 1040-4651
    ISSN (online) 1532-298X
    ISSN 1040-4651
    DOI 10.1105/tpc.19.00777
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: MGO3 and GIP1 act synergistically for the maintenance of centromeric cohesion.

    Batzenschlager, Morgane / Schmit, Anne-Catherine / Herzog, Etienne / Fuchs, Joerg / Schubert, Veit / Houlné, Guy / Chabouté, Marie-Edith

    Nucleus (Austin, Tex.)

    2017  Volume 8, Issue 1, Page(s) 98–105

    Abstract: The control of genomic maintenance during S phase is crucial in eukaryotes. It involves the establishment of sister chromatid cohesion, ensuring faithful chromosome segregation, as well as proper DNA replication and repair to preserve genetic information. ...

    Abstract The control of genomic maintenance during S phase is crucial in eukaryotes. It involves the establishment of sister chromatid cohesion, ensuring faithful chromosome segregation, as well as proper DNA replication and repair to preserve genetic information. In animals, nuclear periphery proteins - including inner nuclear membrane proteins and nuclear pore-associated components - are key factors which regulate DNA integrity. Corresponding functional homologues are not so well known in plants which may have developed specific mechanisms due to their sessile life. We have already characterized the Gamma-tubulin Complex Protein 3-interacting proteins (GIPs) as essential regulators of centromeric cohesion at the nuclear periphery. GIPs were also shown to interact with TSA1, first described as a partner of the epigenetic regulator MGOUN3 (MGO3)/BRUSHY1 (BRU1)/TONSOKU (TSK) involved in genomic maintenance. Here, using genetic analyses, we show that the mgo3gip1 mutants display an impaired and pleiotropic development including fasciation. We also provide evidence for the contribution of both MGO3 and GIP1 to the regulation of centromeric cohesion in Arabidopsis.
    MeSH term(s) Arabidopsis/cytology ; Arabidopsis/genetics ; Arabidopsis/metabolism ; Arabidopsis Proteins/genetics ; Arabidopsis Proteins/metabolism ; Carrier Proteins/genetics ; Carrier Proteins/metabolism ; Centromere/metabolism ; Chromatids/metabolism ; DNA Replication ; Mutation ; Phenotype
    Chemical Substances Arabidopsis Proteins ; Carrier Proteins ; GIP1 protein, Arabidopsis ; MGOUN3 protein, Arabidopsis
    Language English
    Publishing date 2017-01-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2619626-8
    ISSN 1949-1042 ; 1949-1034
    ISSN (online) 1949-1042
    ISSN 1949-1034
    DOI 10.1080/19491034.2016.1276142
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: GIP/MZT1 proteins orchestrate nuclear shaping.

    Batzenschlager, Morgane / Herzog, Etienne / Houlné, Guy / Schmit, Anne-Catherine / Chabouté, Marie-Edith

    Frontiers in plant science

    2014  Volume 5, Page(s) 29

    Abstract: The functional organization of the nuclear envelope (NE) is only just emerging in plants with the recent characterization of NE protein complexes and their molecular links to the actin cytoskeleton. The NE also plays a role in microtubule nucleation by ... ...

    Abstract The functional organization of the nuclear envelope (NE) is only just emerging in plants with the recent characterization of NE protein complexes and their molecular links to the actin cytoskeleton. The NE also plays a role in microtubule nucleation by recruiting γ-Tubulin Complexes (γ-TuCs) which contribute to the establishment of a robust mitotic spindle. γ-tubulin Complex Protein 3 (GCP3)-interacting proteins (GIPs) have been identified recently as integral components of γ-TuCs. GIPs have been conserved throughout evolution and are also named MZT1 (mitotic-spindle organizing protein 1). This review focuses on recent data investigating the role of GIP/MZT1 at the NE, including insights from the study of GIP partners. It also uncovers new functions for GIP/MZT1 during interphase and highlights a current view of NE-associated components which are critical for nuclear shaping during both cell division and differentiation.
    Language English
    Publishing date 2014-02-07
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2613694-6
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2014.00029
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Correction: An essential role for α4A-tubulin in platelet biogenesis.

    Strassel, Catherine / Magiera, Maria M / Dupuis, Arnaud / Batzenschlager, Morgane / Hovasse, Agnès / Pleines, Irina / Guéguen, Paul / Eckly, Anita / Moog, Sylvie / Mallo, Léa / Kimmerlin, Quentin / Chappaz, Stéphane / Strub, Jean-Marc / Kathiresan, Natarajan / Salle, Henri de la / Van Dorsselaer, Alain / Ferec, Claude / Py, Jean-Yves / Gachet, Christian /
    Schaeffer-Reiss, Christine / Kile, Benjamin T / Janke, Carsten / Lanza, François

    Life science alliance

    2021  Volume 4, Issue 8

    Language English
    Publishing date 2021-06-21
    Publishing country United States
    Document type Journal Article ; Published Erratum
    ISSN 2575-1077
    ISSN (online) 2575-1077
    DOI 10.26508/lsa.202101132
    Database MEDical Literature Analysis and Retrieval System OnLINE

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