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  1. Article ; Online: Testosterone Treatment and Fractures in Men with Hypogonadism. Reply.

    Snyder, Peter J / Bauer, Douglas C

    The New England journal of medicine

    2024  Volume 390, Issue 14, Page(s) 1343

    MeSH term(s) Male ; Humans ; Testosterone/therapeutic use ; Hypogonadism/drug therapy ; Fractures, Bone/etiology
    Chemical Substances Testosterone (3XMK78S47O)
    Language English
    Publishing date 2024-04-10
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc2401934
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ua VI Zs.34: Show issues Location:
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  2. Article ; Online: The Importance of Careful Patient Selection in the Use of Follow-up Bone Mineral Density Testing.

    Bauer, Douglas C

    JAMA internal medicine

    2020  Volume 180, Issue 9, Page(s) 1240–1241

    MeSH term(s) Absorptiometry, Photon ; Bone Density ; Female ; Follow-Up Studies ; Fractures, Bone ; Humans ; Patient Selection ; Postmenopause
    Language English
    Publishing date 2020-09-23
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2699338-7
    ISSN 2168-6114 ; 2168-6106
    ISSN (online) 2168-6114
    ISSN 2168-6106
    DOI 10.1001/jamainternmed.2020.4818
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    Ua VI Zs.119: Show issues Location:
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  3. Article ; Online: Clinical Use of Bone Turnover Markers.

    Bauer, Douglas C

    JAMA

    2019  Volume 322, Issue 6, Page(s) 569–570

    Language English
    Publishing date 2019-07-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2019.9372
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  4. Article ; Online: Bone Turnover Markers in Osteoporosis-Reply.

    Bauer, Douglas C

    JAMA

    2019  Volume 322, Issue 23, Page(s) 2344

    MeSH term(s) Bone Density ; Bone Remodeling ; Humans ; Osteoporosis
    Language English
    Publishing date 2019-12-17
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2019.17671
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  5. Article ; Online: Review: Long-term alendronate or zoledronic acid reduces fractures in postmenopausal women with osteoporosis.

    Bauer, Douglas C

    Annals of internal medicine

    2019  Volume 171, Issue 4, Page(s) JC22

    MeSH term(s) Alendronate ; Female ; Holidays ; Humans ; Osteoporosis ; Postmenopause ; Zoledronic Acid
    Chemical Substances Zoledronic Acid (6XC1PAD3KF) ; Alendronate (X1J18R4W8P)
    Language English
    Publishing date 2019-11-29
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 336-0
    ISSN 1539-3704 ; 0003-4819
    ISSN (online) 1539-3704
    ISSN 0003-4819
    DOI 10.7326/ACPJ201908200-022
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    Ua VI Zs.178/2: Show issues Location:
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  6. Article ; Online: Osteoporosis Treatment After Hip Fracture: Bad News and Getting Worse.

    Bauer, Douglas C

    JAMA network open

    2018  Volume 1, Issue 3, Page(s) e180844

    MeSH term(s) Hip Fractures ; Humans ; Osteoporosis
    Language English
    Publishing date 2018-07-06
    Publishing country United States
    Document type Journal Article ; Comment
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2018.0844
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  7. Article ; Online: Bisphosphonate Drug Holidays in Primary Care: When and What to Do Next?

    Bauer, Douglas C / Abrahamsen, Bo

    Current osteoporosis reports

    2021  Volume 19, Issue 2, Page(s) 182–188

    Abstract: Purpose of review: This review describes the rational for bisphosphonate holidays, summaries key evidence to support the concept, and provides a roadmap to help clinicians initiate, monitor, and discontinue a bisphosphonate drug holiday.: Recent ... ...

    Abstract Purpose of review: This review describes the rational for bisphosphonate holidays, summaries key evidence to support the concept, and provides a roadmap to help clinicians initiate, monitor, and discontinue a bisphosphonate drug holiday.
    Recent findings: Randomized trials and data from large observational studies are available to determine the short and long-term bisphosphonate benefits (prevention of fracture) and harms (principally atypical femoral fractures and osteonecrosis of the jaw). Mounting evidence points towards a causal relationship between bisphosphonate use and AFF and ONJ, particularly with > 5 years of use. Multiple studies now confirm the risk of AFF falls rapidly after BPs are discontinued. Osteoporosis patients without previous hip, vertebral, or multiple non-spine fractures who are successfully treated with oral bisphosphonates for 5 years (3 years if intravenous), should be offered a 3-5 year drug holiday, particularly if hip BMD T-score is > - 2.5. Bisphosphonates should only be continued beyond 10 years (6 years if parenteral) in patients at very high risk of fracture.
    MeSH term(s) Bone Density Conservation Agents/administration & dosage ; Drug Administration Schedule ; Humans ; Osteoporosis/drug therapy ; Primary Health Care
    Chemical Substances Bone Density Conservation Agents
    Language English
    Publishing date 2021-02-02
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2186581-4
    ISSN 1544-2241 ; 1544-1873
    ISSN (online) 1544-2241
    ISSN 1544-1873
    DOI 10.1007/s11914-021-00660-4
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    Zs.A 6146: Show issues Location:
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  8. Article ; Online: Circulating IL-10 is associated with reduced risk of prostate cancer in a prospective cohort of elderly men: the MrOS Study.

    Thomas, Claire E / Bauer, Douglas C / Yuan, Jian-Min / Cauley, Jane A

    Cancer causes & control : CCC

    2022  

    Abstract: Purpose: Prostate cancer (PCa) is the most commonly diagnosed cancer in men, resulting in a large cancer burden given a relatively higher 5-year survival rate of patients after cancer diagnosis. The underlying etiology of prostate cancer is not well ... ...

    Abstract Purpose: Prostate cancer (PCa) is the most commonly diagnosed cancer in men, resulting in a large cancer burden given a relatively higher 5-year survival rate of patients after cancer diagnosis. The underlying etiology of prostate cancer is not well understood. Chronic inflammation plays a significant role in carcinogenesis overall and may be involved in the development of PCa, but immune-related biomarker studies in prostate cancer are limited.
    Methods: The associations of serum concentrations of cytokines, systemic immune biomarkers, with risk of PCa were assessed in a randomly selected sub-cohort (n = 798, mean age = 73 years) of the Osteoporotic Fractures in Men (MrOS) study, a prospective cohort of older men. At baseline, we measured serum interleukin (IL)-6, C-reactive protein (CRP), tumor necrosis factor alpha (TNFα), soluble receptors (SR) of IL-6 (IL-6SR) and TNF (TNFαSR1 and TNFαSR2), and IL-10. The risk of PCa was calculated for higher tertile levels of measured individual cytokines relative to the lowest tertile using Cox proportional hazards regression models.
    Results: After an average 6 years of follow-up, 59 men developed incident PCa. Men in the middle or highest tertile of IL-10 had a statistically significant 50% lower risk of PCa compared to the lowest tertile (hazard ratio = 0.50, 95% confidence interval = 0.30-0.84). There was no significant association between any of the other cytokines measured and PCa risk.
    Conclusion: IL-10, an anti-inflammatory cytokine, was associated with lower risk of PCa. Further research of IL-10 and inflammation in relation to PCa development is warranted.
    Language English
    Publishing date 2022-10-14
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1064022-8
    ISSN 1573-7225 ; 0957-5243
    ISSN (online) 1573-7225
    ISSN 0957-5243
    DOI 10.1007/s10552-022-01639-x
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    Zs.A 3375: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  9. Article ; Online: Screening Tests for Osteoporosis: Too Few for Some, Too Many for Others.

    Bauer, Douglas C

    Journal of general internal medicine

    2015  Volume 30, Issue 12, Page(s) 1722–1723

    MeSH term(s) Female ; Health Services Misuse/statistics & numerical data ; Humans ; Mass Screening/utilization ; Osteoporosis/diagnosis
    Language English
    Publishing date 2015-12
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 639008-0
    ISSN 1525-1497 ; 0884-8734
    ISSN (online) 1525-1497
    ISSN 0884-8734
    DOI 10.1007/s11606-015-3446-8
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    Zs.A 2205: Show issues Location:
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  10. Article ; Online: The Reply.

    Gencer, Baris / Bauer, Douglas C / Rodondi, Nicolas

    The American journal of medicine

    2021  Volume 134, Issue 1, Page(s) e71

    MeSH term(s) Aged ; Humans ; Hypothyroidism ; Thyroxine
    Chemical Substances Thyroxine (Q51BO43MG4)
    Language English
    Publishing date 2021-01-20
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80015-6
    ISSN 1555-7162 ; 1873-2178 ; 0002-9343 ; 1548-2766
    ISSN (online) 1555-7162 ; 1873-2178
    ISSN 0002-9343 ; 1548-2766
    DOI 10.1016/j.amjmed.2020.09.008
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