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  1. Book ; Online: Houses, Secrets, and the Closet

    Bauer, Gero

    2016  

    Abstract: Houses, Secrets, and the Closet« investigates the literary production of masculinities and their relation to secrets and sexualities in 18th and 19th century fiction. It focusses on close readings of Gothic fiction, Sensation Novels, and tales by Horace ...

    Abstract »Houses, Secrets, and the Closet« investigates the literary production of masculinities and their relation to secrets and sexualities in 18th and 19th century fiction. It focusses on close readings of Gothic fiction, Sensation Novels, and tales by Horace Walpole, Ann Radcliffe, William Godwin, Mary Elizabeth Braddon, Wilkie Collins, and Henry James. The study approaches these texts through the lens of domestic space, gender, knowledge, and power. This approach serves to investigate the cultural roots of the »closet« - the male homosexual secret - which reveals a more general notion of male secrecy in modern society. The study thus contributes to a better understanding of the cultural history of masculinities and sexualities
    Keywords Literature (General)
    Size 1 electronic resource ( p.)
    Publisher transcript Verlag
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT020097925
    ISBN 9783837634686 ; 9783839434680 ; 383763468X ; 3839434688
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article: Geschichte der Epileptologie in Österreich

    Bauer, G.

    Neurologisch : Sonderausgabe

    2021  Volume -, Issue 3, Page(s) 42

    Language German
    Document type Article
    ZDB-ID 2970821-7
    Database Current Contents Medicine

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 7184 -Sonderausg.-: Show issues Location:
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  3. Article: Inhibition of Membrane-Associated Catalase, Extracellular ROS/RNS Signaling and Aquaporin/H

    Bauer, Georg

    Antioxidants (Basel, Switzerland)

    2021  Volume 10, Issue 10

    Abstract: The human gastric carcinoma cell line MKN-45 is a prototype of bona fide tumor cells, as it is protected from the NADPH oxidase-1 (NOX-1)-driven HOCl- and nitric oxide (NO)/peroxynitrite apoptosis-inducing signaling pathways by a membrane-associated ... ...

    Abstract The human gastric carcinoma cell line MKN-45 is a prototype of bona fide tumor cells, as it is protected from the NADPH oxidase-1 (NOX-1)-driven HOCl- and nitric oxide (NO)/peroxynitrite apoptosis-inducing signaling pathways by a membrane-associated catalase. The use of inhibitors/scavengers shows that inhibition of membrane-associated catalase is sufficient for the activation of NO/peroxynitrite or HOCl signaling. However, this signaling is not sufficient for apoptosis induction, as intracellular glutathione peroxidase/glutathione counteracts these signaling effects. Therefore, intrusion of extracellular tumor cell-derived H
    Language English
    Publishing date 2021-10-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704216-9
    ISSN 2076-3921
    ISSN 2076-3921
    DOI 10.3390/antiox10101585
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The potential significance of high avidity immunoglobulin G (IgG) for protective immunity towards SARS-CoV-2.

    Bauer, Georg

    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

    2021  Volume 106, Page(s) 61–64

    Abstract: Background: Avidity is defined as the strength of binding between immunoglobulin G (IgG) and its specific target epitope. IgG of high avidity is established during affinity maturation. Failure to achieve high avidity IgG may result in a lack of ... ...

    Abstract Background: Avidity is defined as the strength of binding between immunoglobulin G (IgG) and its specific target epitope. IgG of high avidity is established during affinity maturation. Failure to achieve high avidity IgG may result in a lack of protective immunity towards infection and disease. It is known that the interaction between SARS-CoV-2 spike protein and its cellular receptor is driven by high affinity. Therefore, it is predictable that protective antibodies towards SARS-CoV-2 should show high affinity/avidity. AVIDITY AFTER SARS-COV-2 INFECTION: Recent findings by several groups demonstrate that the serological response towards infection with SARS-CoV-2 and seasonal coronaviruses is characterized by incomplete avidity maturation, followed by a decline of the serological response. This response might facilitate reinfection, prevent herd immunity and potentially allow repeated cycles of infection. CONSEQUENCES FOR VACCINATION TOWARDS SARS-COV-2: Therefore, the sole focus on antibody titers reached after vaccination towards SARS-CoV-2 might not be sufficient to evaluate the degree of achieved protection. Rather, it is suggested to include avidity determination to optimize vaccination protocols and achieve high avidity IgG directed towards SARS-CoV-2 through vaccination. Avidity determination might also be useful to control for truly protective immunity towards SARS-CoV-2 in individual cases.
    Language English
    Publishing date 2021-03-10
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 1331197-9
    ISSN 1878-3511 ; 1201-9712
    ISSN (online) 1878-3511
    ISSN 1201-9712
    DOI 10.1016/j.ijid.2021.01.061
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4516: Show issues Location:
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  5. Article ; Online: Comment to the manuscript by William P. Hausdorff and Jorge Flores: Low-dose and oral exposure to SARS-CoV-2 may help us understand and prevent severe COVID-19, IJID 103 (2021) 37-41.

    Bauer, Georg

    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

    2021  Volume 107, Page(s) 251

    MeSH term(s) COVID-19 ; Humans ; SARS-CoV-2
    Language English
    Publishing date 2021-04-02
    Publishing country Canada
    Document type Letter ; Comment
    ZDB-ID 1331197-9
    ISSN 1878-3511 ; 1201-9712
    ISSN (online) 1878-3511
    ISSN 1201-9712
    DOI 10.1016/j.ijid.2021.03.084
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Improved demodulated phase signal resolution for carrier signals with small modulation index by clipping and synchronous sampling for heterodyne interferometers.

    Yu, M / Schewe, M / Bauer, G / Rembe, C

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 8570

    Abstract: Digitization of phase-modulated carrier signals with a commercially available analog-to-digital converter (ADC) is a common task in many communication and sensor applications. ADCs deliver phase-modulated digital carrier signals, which are numerically ... ...

    Abstract Digitization of phase-modulated carrier signals with a commercially available analog-to-digital converter (ADC) is a common task in many communication and sensor applications. ADCs deliver phase-modulated digital carrier signals, which are numerically demodulated in order to extract the relevant information. However, the limited dynamic ranges of available ADCs limit the carrier-to-noise ratio of carrier signals after digitization. Correspondingly, the resolution of the demodulated digital signal is degraded. We demonstrate a sampling method with a simple demodulation scheme for phase-modulated signals with a small modulation index. Our new scheme overcomes the limitation due to digital noise defined by the ADC. Through simulations and experiments, we provide evidence that our method can improve the resolution of the demodulated digital signal significantly, when the carrier-to-noise ratio of phase-modulated signals is limited by digital noise. We employ our sampling and demodulation scheme to solve the problem of a possible degradation of measurement resolution after digital demodulation in heterodyne interferometers measuring small vibration amplitudes.
    Language English
    Publishing date 2023-05-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-35000-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The variability of the serological response to SARS-corona virus-2: Potential resolution of ambiguity through determination of avidity (functional affinity).

    Bauer, Georg

    Journal of medical virology

    2020  Volume 93, Issue 1, Page(s) 311–322

    Abstract: Data on the serological response toward severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 16 recent reports were analyzed and a high degree of variability was shown. Immunoglobulin M (IgM) responses were either found earlier than IgG, or ... ...

    Abstract Data on the serological response toward severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 16 recent reports were analyzed and a high degree of variability was shown. Immunoglobulin M (IgM) responses were either found earlier than IgG, or together with IgG, later than IgG, or were missing. Therefore, clear distinctions between early, intermediate, and past infections are obviously not possible merely on the basis of IgM and IgG determinations. A review of publications on the serology of other virus groups shows that variable IgM responses can be found as well and therefore are not unique for SARS-CoV-2 infections. A model to explain this variability is proposed. The inclusion of avidity determination into regular diagnostic procedures has allowed to resolve such "atypical" serological constellations. The potential use of avidity determination for the diagnosis of COVID-19, for risk assessment, epidemiological studies, analysis of cross reactions, as well as for the control of vaccination programs is suggested and discussed.
    MeSH term(s) Antibodies, Viral/blood ; Antibody Affinity ; COVID-19/blood ; COVID-19/diagnosis ; COVID-19 Serological Testing ; Humans ; SARS-CoV-2/immunology ; Serologic Tests
    Chemical Substances Antibodies, Viral
    Keywords covid19
    Language English
    Publishing date 2020-07-15
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 752392-0
    ISSN 1096-9071 ; 0146-6615
    ISSN (online) 1096-9071
    ISSN 0146-6615
    DOI 10.1002/jmv.26262
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1320: Show issues Location:
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  8. Book ; Thesis: Identifizierung und Charakterisierung von Tetracyclin-RNA-Interaktionen in E. coli

    Bauer, Gesine

    2005  

    Author's details vorgelegt von Gesine Bauer
    Language German
    Size V, 138 S. : Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Erlangen-Nürnberg, Univ., Diss. 2005
    HBZ-ID HT014541697
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2004 D 1930 order for loan Magazin

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  9. Article ; Online: Intercellular singlet oxygen-mediated bystander signaling triggered by long-lived species of cold atmospheric plasma and plasma-activated medium.

    Bauer, Georg

    Redox biology

    2019  Volume 26, Page(s) 101301

    Abstract: Treatment of tumor cells with ... ...

    Abstract Treatment of tumor cells with H
    MeSH term(s) Alcohol Oxidoreductases/metabolism ; Apoptosis/drug effects ; Caspases/metabolism ; Cell Line, Tumor ; Dose-Response Relationship, Drug ; Humans ; Hydrogen Peroxide/metabolism ; Hydrogen Peroxide/pharmacology ; Intracellular Space/metabolism ; Metabolic Networks and Pathways ; Models, Biological ; NADPH Oxidase 1/metabolism ; Nitric Oxide/metabolism ; Nitrites/metabolism ; Nitrites/pharmacology ; Plasma Gases/pharmacology ; Signal Transduction/drug effects ; Singlet Oxygen/metabolism
    Chemical Substances Nitrites ; Plasma Gases ; Singlet Oxygen (17778-80-2) ; Nitric Oxide (31C4KY9ESH) ; Hydrogen Peroxide (BBX060AN9V) ; Alcohol Oxidoreductases (EC 1.1.-) ; NADPH Oxidase 1 (EC 1.6.3.-) ; Caspases (EC 3.4.22.-)
    Language English
    Publishing date 2019-08-16
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2213-2317
    ISSN (online) 2213-2317
    DOI 10.1016/j.redox.2019.101301
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The synergistic effect between hydrogen peroxide and nitrite, two long-lived molecular species from cold atmospheric plasma, triggers tumor cells to induce their own cell death.

    Bauer, Georg

    Redox biology

    2019  Volume 26, Page(s) 101291

    Abstract: Nitrite and ... ...

    Abstract Nitrite and H
    MeSH term(s) Apoptosis/drug effects ; Cell Death/drug effects ; Cell Line, Tumor ; Humans ; Hydrogen Peroxide/metabolism ; Hydrogen Peroxide/pharmacology ; Kinetics ; Metabolic Networks and Pathways ; Nitric Oxide/metabolism ; Nitrites/metabolism ; Nitrites/pharmacology ; Oxidation-Reduction/drug effects ; Plasma Gases/pharmacology ; Reactive Oxygen Species/metabolism
    Chemical Substances Nitrites ; Plasma Gases ; Reactive Oxygen Species ; Nitric Oxide (31C4KY9ESH) ; Hydrogen Peroxide (BBX060AN9V)
    Language English
    Publishing date 2019-08-08
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2213-2317
    ISSN (online) 2213-2317
    DOI 10.1016/j.redox.2019.101291
    Database MEDical Literature Analysis and Retrieval System OnLINE

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