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  1. Book ; Thesis: Die Aspergillose bei importierten Psittaziden in Quarantäne und die Entwicklung eines für die Aspergillenserologie spezifischen Elisa

    Baumgartner, Ruth

    1989  

    Size 60 S. : graph. Darst.
    Publishing country Switzerland
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Zürich, Univ., Diss., 1989
    HBZ-ID HT003598526
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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  2. Article ; Online: Comparing the accuracy of prediction models to detect clinically relevant post-hepatectomy liver failure early after major hepatectomy.

    Baumgartner, Ruth / Engstrand, Jennie / Rajala, Patric / Grip, Jonathan / Ghorbani, Poya / Sparrelid, Ernesto / Gilg, Stefan

    The British journal of surgery

    2023  Volume 111, Issue 1

    Abstract: Background: Arterial lactate measurements were recently suggested as an early predictor of clinically relevant post-hepatectomy liver failure (PHLF). This needed to be evaluated in the subgroup of major hepatectomies only.: Method: This observational ...

    Abstract Background: Arterial lactate measurements were recently suggested as an early predictor of clinically relevant post-hepatectomy liver failure (PHLF). This needed to be evaluated in the subgroup of major hepatectomies only.
    Method: This observational cohort study included consecutive elective major hepatectomies at Karolinska University Hospital from 2010 to 2018. Clinical risk factors for PHLF, perioperative arterial lactate measurements and routine lab values were included in uni- and multivariable regression analysis. Receiver operating characteristics and risk cut-offs were calculated.
    Results: In total, 649 patients constituted the study cohort, of which 92 developed PHLF grade B/C according to the International Study Group of Liver Surgery (ISGLS). Lactate reached significantly higher intra- and postoperative levels in PHLF grades B and C compared to grade A or no liver failure (all P < 0.002). Lactate on postoperative day (POD) 1 was superior to earlier measurement time points in predicting PHLF B/C (AUC 0.75), but was outperformed by both clinical risk factors (AUC 0.81, P = 0.031) and bilirubin POD1 (AUC 0.83, P = 0.013). A multivariable logistic regression model including clinical risk factors and bilirubin POD1 had the highest AUC of 0.87 (P = 0.006), with 56.6% sensitivity and 94.7% specificity for PHLF grade B/C (cut-off ≥0.32). The model identified 46.7% of patients with 90-day mortality and had an equally good discriminatory potential for mortality as the established ISGLS criteria for PHLF grade B/C but could be applied already on POD1.
    Conclusion: The potential of lactate to predict PHLF following major hepatectomy was inferior to a prediction model consisting of clinical risk factors and bilirubin on first post-operative day.
    MeSH term(s) Humans ; Hepatectomy/adverse effects ; Liver Failure/diagnosis ; Liver Failure/etiology ; Liver Neoplasms/surgery ; Bilirubin ; Lactates ; Retrospective Studies ; Postoperative Complications/diagnosis ; Postoperative Complications/etiology ; Carcinoma, Hepatocellular/surgery
    Chemical Substances Bilirubin (RFM9X3LJ49) ; Lactates
    Language English
    Publishing date 2023-12-17
    Publishing country England
    Document type Observational Study ; Journal Article
    ZDB-ID 2985-3
    ISSN 1365-2168 ; 0263-1202 ; 0007-1323 ; 1355-7688
    ISSN (online) 1365-2168
    ISSN 0263-1202 ; 0007-1323 ; 1355-7688
    DOI 10.1093/bjs/znad433
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Angioedema as a predominant symptom of

    Bal, Christina / Baumgartner, Ruth / Gompelmann, Daniela / Idzko, Marco

    BMJ case reports

    2021  Volume 14, Issue 3

    Abstract: A 41-year-old woman was referred to our hospital with a 6-week history of severe angioedema, dyspnoea and coughing. Initial investigations focused on common causes of angioedema. Clinical presentation and resistance to treatment with antihistamines and ... ...

    Abstract A 41-year-old woman was referred to our hospital with a 6-week history of severe angioedema, dyspnoea and coughing. Initial investigations focused on common causes of angioedema. Clinical presentation and resistance to treatment with antihistamines and steroids made histamine-mediated angioedema unlikely. Bradykinin-mediated angioedema, such as hereditary or drug-induced angioedema, was excluded by a thorough history investigation and laboratory testing for C1-esterase and C4.In rare cases, exogen pathogens cause angioedema. After profound testing for respiratory pathogens,
    MeSH term(s) Adult ; Angioedema/diagnosis ; Angioedema/etiology ; Antibodies, Bacterial ; Bordetella pertussis ; Bradykinin ; Female ; Humans ; Whooping Cough/complications ; Whooping Cough/diagnosis ; Whooping Cough/drug therapy
    Chemical Substances Antibodies, Bacterial ; Bradykinin (S8TIM42R2W)
    Language English
    Publishing date 2021-03-02
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2020-239243
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Impact of post-hepatectomy liver failure on morbidity and short- and long-term survival after major hepatectomy.

    Baumgartner, Ruth / Gilg, Stefan / Björnsson, Bergthor / Hasselgren, Kristina / Ghorbani, Poya / Sauter, Christina / Stål, Per / Sandstöm, Per / Sparrelid, Ernesto / Engstrand, Jennie

    BJS open

    2022  Volume 6, Issue 4

    Abstract: Background: Post-hepatectomy liver failure (PHLF) is one of the most serious postoperative complications after hepatectomy. The aim of this study was to assess the impact of the International Study Group of Liver Surgery (ISGLS) definition of PHLF on ... ...

    Abstract Background: Post-hepatectomy liver failure (PHLF) is one of the most serious postoperative complications after hepatectomy. The aim of this study was to assess the impact of the International Study Group of Liver Surgery (ISGLS) definition of PHLF on morbidity and short- and long-term survival after major hepatectomy.
    Methods: This was a retrospective review of all patients who underwent major hepatectomy (three or more liver segments) for various liver tumours between 2010 and 2018 at two Swedish tertiary centres for hepatopancreatobiliary surgery. Descriptive statistics, regression models, and survival analyses were used.
    Results: A total of 799 patients underwent major hepatectomy, of which 218 patients (27 per cent) developed ISGLS-defined PHLF, including 115 patients (14 per cent) with ISGLS grade A, 76 patients (10 per cent) with grade B, and 27 patients (3 per cent) with grade C. The presence of cirrhosis, perihilar cholangiocarcinoma, and gallbladder cancer, right-sided hemihepatectomy and trisectionectomy all significantly increased the risk of clinically relevant PHLF (grades B and C). Clinically relevant PHLF increased the risk of 90-day mortality and was associated with impaired long-term survival. ISGLS grade A had more major postoperative complications compared with no PHLF but failed to be an independent predictor of both 90-day mortality and long-term survival. The impact of PHLF grade B/C on long-term survival was no longer present in patients surviving the first 90 days after surgery.
    Conclusions: The presently used ISGLS definition for PHLF should be reconsidered regarding mortality as only PHLF grade B/C was associated with a negative impact on short-term survival; however, even ISGLS grade A had clinical implications.
    MeSH term(s) Hepatectomy/adverse effects ; Humans ; Liver Failure/epidemiology ; Liver Failure/etiology ; Liver Neoplasms/complications ; Liver Neoplasms/surgery ; Morbidity ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology
    Language English
    Publishing date 2022-08-04
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2474-9842
    ISSN (online) 2474-9842
    DOI 10.1093/bjsopen/zrac097
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Utilization and Efficacy of Palliative Chemotherapy for Locally Advanced or Metastatic Gastroesophageal Carcinoma.

    Baumgartner, Ruth / Taghizadeh, Hossein / Jomrich, Gerd / Schoppmann, Sebastian Friedrich / Preusser, Matthias / Ilhan-Mutlu, Aysegul

    Anticancer research

    2020  Volume 40, Issue 2, Page(s) 965–975

    Abstract: Background/aim: A standard treatment recommendation for advanced stage gastroesophageal cancer is still missing.: Patients and methods: We retrospectively analyzed clinical data of patients with inoperable locally advanced or metastatic ... ...

    Abstract Background/aim: A standard treatment recommendation for advanced stage gastroesophageal cancer is still missing.
    Patients and methods: We retrospectively analyzed clinical data of patients with inoperable locally advanced or metastatic gastroesophageal cancer treated between 2001 and 2017 at the Vienna General Hospital, Austria.
    Results: Administration of systemic therapy was positively associated with overall survival (OS) (469 days vs. 185 days; p<0.001), while palliative gastrectomy or radiotherapy showed no correlation. OS was significantly longer in patients receiving capecitabine/oxaliplatin (XELOX) vs. leucovorin/5-FU/oxaliplatin (FOLFOX) (600 days vs. 327 days, p<0.05). Comparison of doublet vs. triplet chemotherapies showed no difference in OS, but triplet chemotherapy resulted in more adverse events. The anti-HER2-antibody trastuzumab doubled OS (836 days vs. 399 days, p=0.053).
    Conclusion: Capecitabine may be preferably used over infused 5-FU and doublet chemotherapy over triplet chemotherapy in the first-line palliative setting of advanced gastroesophageal cancer.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Esophageal Neoplasms/drug therapy ; Esophageal Neoplasms/mortality ; Esophageal Neoplasms/pathology ; Esophagogastric Junction/pathology ; Female ; Humans ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Neoplasm Grading ; Neoplasm Staging ; Palliative Care/methods ; Stomach Neoplasms/drug therapy ; Stomach Neoplasms/mortality ; Stomach Neoplasms/pathology ; Treatment Outcome
    Language English
    Publishing date 2020-01-17
    Publishing country Greece
    Document type Journal Article
    ZDB-ID 604549-2
    ISSN 1791-7530 ; 0250-7005
    ISSN (online) 1791-7530
    ISSN 0250-7005
    DOI 10.21873/anticanres.14030
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book: Krankheiten der Heimtiere

    Gabrisch, Karl / Baumgartner, Ruth / Fehr, Michael / Zwart, Peernel

    (Vet)

    2015  

    Author's details Karl Gabrisch; Peernel Zwart. Hrsg. von Michael Fehr ... Autoren Ruth Baumgartner
    Series title Vet
    Keywords Haustierkrankheit
    Language German
    Size VIII, 1205 S., zahlr. Ill.
    Edition 8., vollst. überarb. Aufl.
    Publisher Schlüter
    Publishing place Hannover
    Document type Book
    ISBN 3899936787 ; 9783842685932 ; 9783899936780 ; 3842685939
    Database Special collection on veterinary medicine and general parasitology

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  7. Article ; Online: Molecular adsorbent recirculating system treatment in patients with post-hepatectomy liver failure: Long-term results of a pilot study.

    Gilg, Stefan / Sparrelid, Ernesto / Engstrand, Jennie / Baumgartner, Ruth / Nowak, Greg / Stål, Per / D'Souza, Melroy / Jansson, Anders / Isaksson, Bengt / Jonas, Eduard / Stromberg, Cecilia

    Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society

    2022  Volume 111, Issue 3, Page(s) 48–55

    Abstract: Background: Post-hepatectomy liver failure (PHLF) is the leading cause of postoperative mortality following major liver resection. Between December 2012 and May 2015, 10 consecutive patients with PHLF (according to the Balzan criteria) following major/ ... ...

    Abstract Background: Post-hepatectomy liver failure (PHLF) is the leading cause of postoperative mortality following major liver resection. Between December 2012 and May 2015, 10 consecutive patients with PHLF (according to the Balzan criteria) following major/extended hepatectomy were included in a prospective treatment study with the molecular adsorbent recirculating system (MARS). Sixty- and 90-day mortality rates were 0% and 10%, respectively. Of the nine survivors, four still had liver dysfunction at 90 days postoperatively. One-year overall survival (OS) of the MARS-PHLF cohort was 50%. The present study aims to assess long-term outcome of this cohort compared to a historical control cohort.
    Methods: To compare long-term outcome of the MARS-PHLF treatment cohort with PHLF patients not treated with MARS, the present study includes all 655 patients who underwent major hepatectomy at Karolinska University Hospital between 2010 and 2018. Patients with PHLF were identified according to the Balzan criteria.
    Results: The cohort was split into three time periods: pre-MARS period (
    Conclusions: MARS treatment may contribute to improved outcome of patients with PHLF. Further studies are needed.The initial pilot study was registered at ClinicalTrials.gov (NCT03011424).
    MeSH term(s) Hepatectomy/adverse effects ; Humans ; Liver Failure/etiology ; Liver Failure/surgery ; Liver Neoplasms/surgery ; Pilot Projects ; Postoperative Complications/etiology ; Postoperative Complications/therapy ; Postoperative Period ; Prospective Studies ; Retrospective Studies
    Language English
    Publishing date 2022-08-24
    Publishing country England
    Document type Clinical Study ; Journal Article
    ZDB-ID 2077691-3
    ISSN 1799-7267 ; 1457-4969
    ISSN (online) 1799-7267
    ISSN 1457-4969
    DOI 10.1177/14574969221112224
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book: Krankheiten der Heimtiere

    Gabrisch, Karl / Baumgartner, Ruth / Fehr, Michael / Gabrisch-Zwart, Heimtiere / Zwart, Peernel

    (Vet)

    2015  

    Author's details Karl Gabrisch; Peernel Zwart. Hrsg. von Michael Fehr ... Autoren Ruth Baumgartner
    Series title Vet
    Keywords Haustierkrankheit
    Language German
    Size VIII, 1205 S., zahlr. Ill.
    Edition 8., vollst. überarb. Aufl.
    Publisher Schlüter
    Publishing place Hannover
    Document type Book
    ISBN 3899936787 ; 9783842685932 ; 9783899936780 ; 3842685939
    Database Former special subject collection: coastal and deep sea fishing

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  9. Book: Krankheiten der Heimtiere

    Baumgartner, Ruth / Gabrisch, Karl

    2001  

    Author's details K. Gabrisch; P. Zwart (Hrsg.). Autoren : R. Baumgartner .̤
    Keywords Haustierkrankheit
    Language German
    Size 1000 S, Ill, 25 cm
    Edition 5., unveränd. Aufl
    Publisher Schlütersche
    Publishing place Hannover
    Document type Book
    Note Literaturangaben
    ISBN 3877065279 ; 9783877065273
    Database Special collection on veterinary medicine and general parasitology

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  10. Book: Krankheiten der Heimtiere

    Baumgartner, Ruth / Gabrisch, Karl

    1998  

    Author's details K. Gabrisch; P. Zwart (Hrsg.). Autoren : R. Baumgartner
    Keywords Haustierkrankheit
    Language German
    Size 1000 S, Ill, 25 cm
    Edition 4., überarb. Aufl
    Publisher Schlüter
    Publishing place Hannover
    Document type Book
    Note Literaturangaben
    ISBN 3877065279 ; 9783877065273
    Database Federal Institute for Risk Assessment

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