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  1. Article ; Online: Impact of negative air pressure in ICU rooms on the risk of pulmonary aspergillosis in COVID-19 patients.

    Ichai, Philippe / Saliba, Faouzi / Baune, Patricia / Daoud, Asma / Coilly, Audrey / Samuel, Didier

    Critical care (London, England)

    2020  Volume 24, Issue 1, Page(s) 538

    MeSH term(s) Aged ; Air Microbiology ; Air Pressure ; Antifungal Agents/therapeutic use ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/complications ; Disease Outbreaks ; Environmental Monitoring/methods ; Female ; Hospital Design and Construction ; Humans ; Intensive Care Units ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/complications ; Pulmonary Aspergillosis/drug therapy ; Pulmonary Aspergillosis/transmission ; Risk Factors ; SARS-CoV-2 ; Ventilation
    Chemical Substances Antifungal Agents
    Keywords covid19
    Language English
    Publishing date 2020-09-01
    Publishing country England
    Document type Letter
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-020-03221-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Prevalence and risk factors of toxigenic

    Jolivet, Sarah / Couturier, Jeanne / Grohs, Patrick / Vilfaillot, Aurélie / Zahar, Jean-Ralph / Frange, Pierre / Casetta, Anne / Moulin, Véronique / Lawrence, Christine / Baune, Patricia / Bourgeois, Cléo / Bouffier, Axel / Laussucq, Claudine / Sienzonit, Lydia / Picard, Simon / Podglajen, Isabelle / Kassis-Chikhani, Najiby / Barbut, Frédéric

    Frontiers in medicine

    2023  Volume 10, Page(s) 1221363

    Abstract: Clostridioides ... ...

    Abstract Clostridioides difficile
    Language English
    Publishing date 2023-07-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2023.1221363
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Impact of negative air pressure in ICU rooms on the risk of pulmonary aspergillosis in COVID-19 patients

    Ichai, Philippe / Saliba, Faouzi / Baune, Patricia / Daoud, Asma / Coilly, Audrey / Samuel, Didier

    Crit Care

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #736411
    Database COVID19

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  4. Article ; Online: Impact of negative air pressure in ICU rooms on the risk of pulmonary aspergillosis in COVID-19 patients

    Ichai, Philippe / Saliba, Faouzi / Baune, Patricia / Daoud, Asma / Coilly, Audrey / Samuel, Didier

    Critical Care

    2020  Volume 24, Issue 1

    Keywords Critical Care and Intensive Care Medicine ; covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2041406-7
    ISSN 1364-8535
    ISSN 1364-8535
    DOI 10.1186/s13054-020-03221-w
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Evaluation of antibiotic prescriptions for urinary tract infections in a geriatric rehabilitation unit.

    Afekouh, Hind / Baune, Patricia / De Falvelly, Diane / Guermah, Fatima / Ghitri, Saïda / Haber, Nicole

    Geriatrie et psychologie neuropsychiatrie du vieillissement

    2017  Volume 15, Issue 1, Page(s) 47–54

    Abstract: Prescription of antibiotic in elderly patients must follow guidelines. to study the quality of antibiotic prescriptions for urinary tract infections (UTI) in the geriatric rehabilitation unit. Over a four-month period, all the antibiotics treatments ... ...

    Title translation Antibiothérapie des infections urinaires en soins de suite et de réadaptation gériatrique.
    Abstract Prescription of antibiotic in elderly patients must follow guidelines. to study the quality of antibiotic prescriptions for urinary tract infections (UTI) in the geriatric rehabilitation unit. Over a four-month period, all the antibiotics treatments prescribed for UTI in the rehabilitation ward were analyzed prospectively by medical experts and confronted with the recommendations of the local antibiotic guidelines. The methodology was based on Gyssens' algorithm. Treatments were considered appropriate if indication, choice of the molecule, duration and dose were approved by the experts, unnecessary if the indication was incorrect, and inappropriate in all other cases. The re-assessment of the prescription between 48 and 72 h was also evaluated. We reviewed 39 prescriptions. About half of all prescriptions (51.3%) was found to be unnecessary due to misdiagnosis, 16 prescriptions (41%) were considered inappropriate (2 for inadequate duration and 14 for inappropriate spectrum of activity, mainly with ceftriaxone prescriptions (9 cases)). Ten prescriptions (25.6%) were re-assessed between 48 and 72 hours after treatment initiation. According to this study, an improvement program was implemented. A diagnostic algorithm for UTI in elderly was drafted and will be integrated into the local guidelines. A supporting document for the re-assessment of the prescriptions 48-72h after treatment initiation was created. We decided to perform an evaluation of antibiotic prescriptions by the subcutaneous route.
    MeSH term(s) Aged ; Aged, 80 and over ; Anti-Bacterial Agents/therapeutic use ; Drug Prescriptions ; Drug Utilization ; Female ; Geriatrics ; Guidelines as Topic ; Hospital Units ; Humans ; Male ; Practice Patterns, Physicians' ; Urinary Tract Infections/drug therapy ; Urinary Tract Infections/microbiology
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2017-03-01
    Publishing country France
    Document type Journal Article
    ISSN 2115-7863
    ISSN (online) 2115-7863
    DOI 10.1684/pnv.2017.0658
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Faecal carriage of multidrug-resistant bacteria and associated risk factors: results from a point prevalence study.

    Grohs, Patrick / Vilfaillot, Aurélie / Zahar, Jean Ralph / Barbut, Frédéric / Frange, Pierre / Casetta, Anne / Moulin, Véronique / Lawrence, Christine / Baune, Patricia / Bourgeois, Cléo / Bouffier, Axel / Laussucq, Claudine / Sienzonit, Lydia / Picard, Simon / Podglajen, Isabelle / Kassis-Chikhani, Najiby

    The Journal of antimicrobial chemotherapy

    2022  Volume 77, Issue 10, Page(s) 2667–2678

    Abstract: Objectives: Since 2003, incidences of carbapenemase-producing Gram-negative bacilli (CP-GNB) and vancomycin-resistant Enterococcus faecium (VRE) have steadily increased in France. We therefore conducted a point prevalence study to estimate carriage ... ...

    Abstract Objectives: Since 2003, incidences of carbapenemase-producing Gram-negative bacilli (CP-GNB) and vancomycin-resistant Enterococcus faecium (VRE) have steadily increased in France. We therefore conducted a point prevalence study to estimate carriage rates of CP-GNB, VRE and ESBL-producing Enterobacterales (ESBL-PE) and associated risk factors.
    Methods: Between September 2019 and January 2020, all inpatients hospitalized on a given day in 11 teaching hospitals in the Paris urban area were eligible. Patient interviews and rectal swab screening results were recorded by dedicated nurses. The swabs were plated onto selective chromogenic media and processed using the GeneXpert® system.
    Results: Of 2396 patients, 364 (15.2%) yielded at least one multiresistant bacterial isolate, including 29 CP-GNB carriers (1.2%), 13 VRE carriers (0.5%) and 338 ESBL-PE carriers (14%). In 15 patients (4.4% of ESBL-PE carriers and 36.6% of CP-GNB/VRE carriers), concomitant CP-GNB/VRE and ESBL-PE carriage was observed. In 7/29 CP-GNB and 7/13 VRE carriers, carbapenemase production and vanA in the screening samples was only detected with Xpert® tests. The OXA-48 gene was predominant in 13/34 CP-GNB isolates from 29 carriers. From the 338 ESBL-PE carriers, 372 isolates were recovered, mainly Escherichia coli (61.2%). Among 379 children, 1.1% carried a CP-GNB/VRE strain, and 12.4% carried an ESBL strain. Previous hospitalization outside mainland France, previous antimicrobial treatment and previous ESBL-PE carriage were the main risk factors associated with CP-GNB and/or VRE carriage.
    Conclusions: The low CP-GNB and VRE prevalence likely reflects the French policy to limit intrahospital spread of CP-GNB and VRE strains.
    MeSH term(s) Child ; Drug Resistance, Multiple, Bacterial/genetics ; Gram-Negative Bacteria ; Gram-Negative Bacterial Infections/microbiology ; Humans ; Prevalence ; Risk Factors ; Vancomycin ; Vancomycin-Resistant Enterococci ; beta-Lactamases/genetics
    Chemical Substances Vancomycin (6Q205EH1VU) ; beta-Lactamases (EC 3.5.2.6)
    Language English
    Publishing date 2022-08-28
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 191709-2
    ISSN 1460-2091 ; 0305-7453
    ISSN (online) 1460-2091
    ISSN 0305-7453
    DOI 10.1093/jac/dkac289
    Database MEDical Literature Analysis and Retrieval System OnLINE

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