LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 89

Search options

  1. Book ; Online ; E-Book: The CAPRISA clinical trials

    Abdool Karim, Quarraisha / Abdool Karim, Salim S. / Baxter, Cheryl

    HIV treatment and prevention

    2017  

    Author's details Quarraisha Abdool Karim, Salim S. Abdool Karim, Cheryl Baxter editors
    Subject code 610
    Language English
    Size 1 Online-Ressource (vi, 243 Seiten), Illustrationen
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019283340
    ISBN 978-3-319-47518-9 ; 9783319475172 ; 3-319-47518-5 ; 3319475177
    DOI 10.1007/978-3-319-47518-9
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Article ; Online: Investing in Africa's scientific future.

    de Oliveira, Tulio / Baxter, Cheryl

    Science (New York, N.Y.)

    2024  Volume 383, Issue 6678, Page(s) eadn4168

    Abstract: Africa bears a disproportionate burden of infectious diseases, accounting for a substantial percentage of global cases. Malaria, HIV/AIDS, tuberculosis, cholera, Ebola, Lassa fever, and other tropical diseases, such as dengue and chikungunya, have had a ... ...

    Abstract Africa bears a disproportionate burden of infectious diseases, accounting for a substantial percentage of global cases. Malaria, HIV/AIDS, tuberculosis, cholera, Ebola, Lassa fever, and other tropical diseases, such as dengue and chikungunya, have had a profound impact on morbidity and mortality. Various factors contribute to the higher prevalence and incidence of infectious diseases in Africa, including socioeconomic challenges, limited access to health care, inadequate sanitation and hygiene infrastructure, climate-related factors, and endemicity of certain diseases in specific regions. A skilled workforce is crucial to addressing these challenges. Unfortunately, many countries in Africa often lack the required resources, and aspiring scientists frequently seek educational and career opportunities abroad, leading to a substantial loss of talent and expertise from the continent. This talent migration, referred to as "brain drain," exacerbates the existing training gaps and hampers the sustainability of research within Africa.
    MeSH term(s) Humans ; Africa/epidemiology ; Workforce ; Communicable Diseases/economics ; Communicable Diseases/epidemiology ; Communicable Diseases/mortality ; Prevalence ; Incidence ; Brain Drain ; Global Burden of Disease ; Genomics/economics ; Genomics/trends
    Language English
    Publishing date 2024-01-04
    Publishing country United States
    Document type Editorial
    ZDB-ID 128410-1
    ISSN 1095-9203 ; 0036-8075
    ISSN (online) 1095-9203
    ISSN 0036-8075
    DOI 10.1126/science.adn4168
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 27: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 77: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: COVID-19: Impact on the HIV and Tuberculosis Response, Service Delivery, and Research in South Africa.

    Abdool Karim, Quarraisha / Baxter, Cheryl

    Current HIV/AIDS reports

    2022  Volume 19, Issue 1, Page(s) 46–53

    Abstract: Purpose of review: To describe how mitigation measures against COVID-19 have impacted HIV and TB research in South Africa.: Recent findings: South Africa has the highest number of COVID-19 (34%) cases in Africa, accounting for 43% of all reported ... ...

    Abstract Purpose of review: To describe how mitigation measures against COVID-19 have impacted HIV and TB research in South Africa.
    Recent findings: South Africa has the highest number of COVID-19 (34%) cases in Africa, accounting for 43% of all reported COVID-19-related deaths on the continent. The country accounts for 20% of all people living with HIV and ranked third in the world for new TB infections in 2019. While South Africa's investments in its HIV and TB responses enabled it to pivot rapidly to respond to the emerging COVID-19 epidemic, it negatively impacted the HIV and TB response through temporary suspension of research, diversion of key resources for HIV and TB control, and patient access to health care facilities; the full extent of this has yet to emerge. Success in integrating responses to the colliding epidemics could potentially enhance survival outcomes and ensure gains made to date in HIV and TB are not reversed and we stay on track toward achieving the UN 2030 Sustainable Development Goals.
    MeSH term(s) COVID-19/epidemiology ; HIV Infections/epidemiology ; Humans ; SARS-CoV-2 ; South Africa/epidemiology ; Tuberculosis/epidemiology ; Tuberculosis/prevention & control
    Language English
    Publishing date 2022-01-22
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2151206-1
    ISSN 1548-3576 ; 1548-3568
    ISSN (online) 1548-3576
    ISSN 1548-3568
    DOI 10.1007/s11904-021-00588-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 5920: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: HIV pre-exposure prophylaxis implementation in Africa: some early lessons.

    Karim, Salim S Abdool / Baxter, Cheryl

    The Lancet. Global health

    2021  Volume 9, Issue 12, Page(s) e1634–e1635

    MeSH term(s) Africa ; Anti-HIV Agents/therapeutic use ; Female ; HIV Infections/epidemiology ; HIV Infections/prevention & control ; Humans ; Male ; Mass Screening/statistics & numerical data ; Pre-Exposure Prophylaxis/statistics & numerical data ; Sexual Behavior/statistics & numerical data
    Chemical Substances Anti-HIV Agents
    Language English
    Publishing date 2021-11-19
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2723488-5
    ISSN 2214-109X ; 2214-109X
    ISSN (online) 2214-109X
    ISSN 2214-109X
    DOI 10.1016/S2214-109X(21)00460-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: HIV incidence trends in Africa: young women at highest risk.

    Karim, Salim S Abdool / Baxter, Cheryl

    The lancet. HIV

    2021  Volume 8, Issue 7, Page(s) e389–e390

    MeSH term(s) Adolescent ; Adult ; Africa/epidemiology ; Female ; HIV Infections/epidemiology ; HIV Infections/transmission ; Humans ; Incidence ; Male ; Prevalence ; Women's Health ; Young Adult
    Language English
    Publishing date 2021-07-01
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2352-3018
    ISSN (online) 2352-3018
    DOI 10.1016/S2352-3018(21)00079-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Article ; Online: Advancing HIV prevention using tenofovir-based pre-exposure prophylaxis.

    Abdool Karim, Salim S / Baxter, Cheryl / Abdool Karim, Quarraisha

    Antiviral therapy

    2022  Volume 27, Issue 2, Page(s) 13596535211067589

    Abstract: Tenofovir-based pre-exposure prophylaxis (PrEP) revolutionized the global HIV prevention landscape. Prior to the proof-of concept trial in 2010, which demonstrated that tenofovir (TFV) could prevent sexual transmission of HIV, prevention options were ... ...

    Abstract Tenofovir-based pre-exposure prophylaxis (PrEP) revolutionized the global HIV prevention landscape. Prior to the proof-of concept trial in 2010, which demonstrated that tenofovir (TFV) could prevent sexual transmission of HIV, prevention options were largely limited to behavior change, condoms, and circumcision. Several subsequent studies evaluating oral tenofovir disoproxil fumarate (TDF) or the TDF/emtricitabine (FTC) combination as PrEP for HIV prevention provided evidence for regulatory approval and inclusion in national and international guidelines. By 2021, 1.5 million people had initiated oral tenofovir-based PrEP, contributing to declines in HIV incidence in some regions. Here we reflect on how oral tenofovir-based PrEP became an important component of combination HIV prevention programs across the globe.
    MeSH term(s) Anti-HIV Agents/therapeutic use ; Emtricitabine/therapeutic use ; HIV Infections/drug therapy ; Humans ; Male ; Pre-Exposure Prophylaxis ; Tenofovir/therapeutic use
    Chemical Substances Anti-HIV Agents ; Tenofovir (99YXE507IL) ; Emtricitabine (G70B4ETF4S)
    Language English
    Publishing date 2022-04-25
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1339842-8
    ISSN 2040-2058 ; 1359-6535
    ISSN (online) 2040-2058
    ISSN 1359-6535
    DOI 10.1177/13596535211067589
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 4877: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 174: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: COVID-19 in Africa: Catalyzing change for sustainable development.

    Abdool Karim, Salim S / Kelemu, Segenet / Baxter, Cheryl

    PLoS medicine

    2021  Volume 18, Issue 11, Page(s) e1003869

    Abstract: Salim Abdool Karim, Segenet Kelemu and Cheryl Baxter discuss COVID-19 impacts and adaptations in Africa. ...

    Abstract Salim Abdool Karim, Segenet Kelemu and Cheryl Baxter discuss COVID-19 impacts and adaptations in Africa.
    MeSH term(s) Africa/epidemiology ; COVID-19/epidemiology ; Food Security ; Food Supply ; Health Resources ; Humans ; Sustainable Development
    Language English
    Publishing date 2021-11-29
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2185925-5
    ISSN 1549-1676 ; 1549-1277
    ISSN (online) 1549-1676
    ISSN 1549-1277
    DOI 10.1371/journal.pmed.1003869
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6042: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: HIV incidence rates in adolescent girls and young women in sub-Saharan Africa.

    Karim, Salim S Abdool / Baxter, Cheryl

    The Lancet. Global health

    2019  Volume 7, Issue 11, Page(s) e1470–e1471

    MeSH term(s) Adolescent ; Africa South of the Sahara ; Female ; HIV Infections ; Humans ; Incidence ; Prevalence ; Sexual Behavior
    Language English
    Publishing date 2019-09-26
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2723488-5
    ISSN 2214-109X ; 2214-109X
    ISSN (online) 2214-109X
    ISSN 2214-109X
    DOI 10.1016/S2214-109X(19)30404-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: The use of PSA as a biomarker of recent semen exposure in female reproductive health studies.

    Mngomezulu, Khanyisile / Mzobe, Gugulethu / Mtshali, Andile / Baxter, Cheryl / Ngcapu, Sinaye

    Journal of reproductive immunology

    2021  Volume 148, Page(s) 103381

    Abstract: Semen contains potent soluble proteins, bacteria, viruses, activated immune cells as well as anti- and pro-inflammatory cytokines that may influence the inflammatory response and alter microbial composition of the female genital tract. The presence of ... ...

    Abstract Semen contains potent soluble proteins, bacteria, viruses, activated immune cells as well as anti- and pro-inflammatory cytokines that may influence the inflammatory response and alter microbial composition of the female genital tract. The presence of semen in the female genital mucosa may be a significant confounder that most studies have failed to control for in their analysis. Prostate-specific antigen (PSA), a protein secreted by the prostate into the urethra during ejaculation, is a well-established biomarker of semen exposure. Several studies have demonstrated discordance between self-reports of sexual behavior and the presence of PSA. Recent semen exposure has been shown to promote pro-inflammatory responses, stimulate the recruitment of activated immune cells and decrease Lactobacilli abundance in the female genital mucosa. As a result, it is important to understand the concordance between self-reported consistent condom use and the presence of semen biomarkers. Furthermore, to ensure that the interpretation of data in clinical studies of the immunological and microbial environment in the female genital mucosa are accurate, it is essential to establish whether semen is present in the vaginal fluid. This review explores the impact of semen exposure on the mucosal microenvironment and assesses the use of the PSA as an objective biomarker of semen exposure to reduce reliance on self-reported sexual intercourse.
    MeSH term(s) Biomarkers/metabolism ; Female ; Humans ; Male ; Mucous Membrane/metabolism ; Prostate-Specific Antigen/metabolism ; Reproductive Health ; Semen/metabolism ; Sexual Behavior ; Vagina/metabolism
    Chemical Substances Biomarkers ; Prostate-Specific Antigen (EC 3.4.21.77)
    Language English
    Publishing date 2021-09-09
    Publishing country Ireland
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 424421-7
    ISSN 1872-7603 ; 0165-0378
    ISSN (online) 1872-7603
    ISSN 0165-0378
    DOI 10.1016/j.jri.2021.103381
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1483: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article: Managing and assembling population-scale data streams, tools and workflows to plan for future pandemics within the INFORM-Africa Consortium.

    Poongavanan, Jenicca / Xavier, Joicymara / Dunaiski, Marcel / Tegally, Houriiyah / Oladejo, Sunday / Ayorinde, Olawole / Wilkinson, Eduan / Baxter, Cheryl / de Oliveira, Tulio

    South African journal of science

    2023  Volume 119, Issue 5-6

    Language English
    Publishing date 2023-05-30
    Publishing country South Africa
    Document type Journal Article
    ZDB-ID 421752-4
    ISSN 0038-2353
    ISSN 0038-2353
    DOI 10.17159/sajs.2023/14659
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2796: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top