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  1. AU="Baxter, J"
  2. AU="Liu, Zhenhong"
  3. AU="Xiaochun Deng"
  4. AU="Anderson, Ciorsdan"
  5. AU="Xiaofang Zhang"
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  1. Book ; Online ; E-Book: Moral responsibility and the psychopath

    Baxter, Jim

    the value of others

    2021  

    Abstract: Are psychopaths morally responsible? Should we argue with them? Remonstrate with them, blame them, sometimes even praise them? Is it worth trying to change them, or should we just try to prevent them from causing harm? In this book, Jim Baxter aims to ... ...

    Author's details Jim Baxter
    Abstract Are psychopaths morally responsible? Should we argue with them? Remonstrate with them, blame them, sometimes even praise them? Is it worth trying to change them, or should we just try to prevent them from causing harm? In this book, Jim Baxter aims to find serious answers to these deep philosophical questions, drawing on contemporary insights from psychiatry, psychology, neuroscience and law. Moral Responsibility and the Psychopath is the first sustained, book-length philosophical work on this important and fascinating topic, and will be of deep interest and importance to researchers in these fields - not to mention anyone who has had to interact with a psychopath in their everyday life.
    Keywords Psychotherapist and patient/Moral and ethical aspects ; Psychotherapy ; Psychopaths
    Subject code 616.89/14
    Language English
    Size 1 online resource (ix, 2121 pages) :, digital, PDF file(s).
    Publisher Cambridge University Press
    Publishing place Cambridge
    Document type Book ; Online ; E-Book
    Note Title from publisher's bibliographic system (viewed on 27 Aug 2021).
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 1-009-03582-7 ; 1-009-03602-5 ; 1-009-02535-X ; 1-316-51686-5 ; 978-1-009-03582-8 ; 978-1-009-03602-3 ; 978-1-009-02535-5 ; 978-1-316-51686-7
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Entangling and disentangling mitotic chromosomes.

    Baxter, Jonathan

    Molecular cell

    2024  Volume 84, Issue 8, Page(s) 1398–1400

    Abstract: The DNA topological challenges generated by cellular manipulation of extremely long DNA fibers remain poorly understood. In this issue of Molecular Cell, Hildebrand et al. ...

    Abstract The DNA topological challenges generated by cellular manipulation of extremely long DNA fibers remain poorly understood. In this issue of Molecular Cell, Hildebrand et al.
    MeSH term(s) DNA Topoisomerases, Type II/genetics ; Chromosomes/genetics ; DNA/genetics ; Mitosis/genetics
    Chemical Substances DNA Topoisomerases, Type II (EC 5.99.1.3) ; DNA (9007-49-2)
    Language English
    Publishing date 2024-04-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1415236-8
    ISSN 1097-4164 ; 1097-2765
    ISSN (online) 1097-4164
    ISSN 1097-2765
    DOI 10.1016/j.molcel.2024.03.025
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5055: Show issues Location:
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  3. Book ; Online: Family Dynamics over the Life Course

    Baxter, Janeen / Lam, Jack / Povey, Jenny / Lee, Rennie / Zubrick, Stephen R.

    Foundations, Turning Points and Outcomes

    (Life Course Research and Social Policies)

    2022  

    Series title Life Course Research and Social Policies
    Keywords Sociology ; Sociology: family & relationships ; Family dynamics in Australia ; Life course transitions in Australia ; Gender inequality in Australia ; Child development in Australia ; Parenting practices and outcomes in Australia ; Families, relationships and wellbeing ; Social and economic inequality ; Families and social disadvantage ; Refugee and culturally diverse families ; LGBTIQ+ families ; Life course and labour market participation ; Ageing and loneliness in the life course ; Social policy on families in Australia ; Emerging directions in life course research ; Life course and education ; Life course and Indigenous families
    Language 0|e
    Size 1 electronic resource (326 pages)
    Publisher Springer Nature
    Publishing place Cham
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021621003
    ISBN 9783031122248 ; 3031122240
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Article ; Online: When is it Safe to Edit the Human Germline?

    Baxter, Janella

    Science and engineering ethics

    2021  Volume 27, Issue 4, Page(s) 43

    Abstract: In the fall of 2018 Jiankui He shocked the international community with the following announcement: two female babies, "Lulu" and "Nana," whose germlines had been modified by the cutting edge, yet profoundly unsafe CRISPR-Cas9 technology had been born. ... ...

    Abstract In the fall of 2018 Jiankui He shocked the international community with the following announcement: two female babies, "Lulu" and "Nana," whose germlines had been modified by the cutting edge, yet profoundly unsafe CRISPR-Cas9 technology had been born. This event galvanized policy makers and scientists to advocate for more explicit and firm regulation of human germline gene editing (GGE). Recent policy proposals attempt to integrate safety considerations and public input to identify specific types of diseases that may be safe targets for human GGE (Sarkar forthcoming; Guttinger. 2019. "Editing the Reactive Genome: Towards Postgenomic Ethics of Germline Editing." Journal of Applied Philosophy. "Editing the Reactive Genome: Towards Postgenomic Ethics of Germline Editing." Journal of Applied Philosophy. "Editing the Reactive Genome: Towards Postgenomic Ethics of Germline Editing." Journal of Applied Philosophy; Lander et al., 2019). This paper argues these policy proposals are inadequate in different ways. While Sarkar (forthcoming) intends to incorporate input from the disability community for the purpose of deciding the value of human GGE, I argue that his strategy for doing so is inadequate. I'll argue that an iterative, deliberative process is a more appropriate framework for allowing the disability community to inform policy on human GGE. Further policy proposals have been framed in terms of monogenetic or single-gene diseases (Guttinger. 2019. "Editing the Reactive Genome: Towards Postgenomic Ethics of Germline Editing." Journal of Applied Philosophy. "Editing the Reactive Genome: Towards Postgenomic Ethics of Germline Editing." Journal of Applied Philosophy. "Editing the Reactive Genome: Towards Postgenomic Ethics of Germline Editing." Journal of Applied Philosophy; Lander et al., 2019). I argue that this way of conceptualizing disease is not what matters for deciding which disorders are viable candidates for human GGE. Instead, what matters is that (1) the disease in question must have (among its set of causes) genes that have a high degree of causal control with respect to the disease and (2) alternative nucleic acid sequences variants that are likely to produce traits deemed desirable must be identified. Previous policy proposals leave (2) unspecified. What conditions must be met for satisfying condition (2) should not be left to individual scientists to decide for themselves. The present proposal offers some guidance on this issue.
    MeSH term(s) Female ; Gene Editing ; Genome ; Germ Cells ; Humans ; Male
    Language English
    Publishing date 2021-07-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 2136491-6
    ISSN 1471-5546 ; 1353-3452
    ISSN (online) 1471-5546
    ISSN 1353-3452
    DOI 10.1007/s11948-021-00320-x
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  5. Article: Modes of spread in social innovation: A social topology case in rural Portugal

    Baxter, J.-S.

    Journal of rural studies

    2023  Volume 99, Issue -, Page(s) 243

    Language English
    Document type Article
    ZDB-ID 252458-2
    ISSN 0743-0167
    Database Current Contents Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

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  6. Article: A Comparison Between Ultrasound Pachymetry and CASIA2 (Anterior-Segment Optical Coherence Tomography) in the Measurement of Central Corneal Thickness.

    Baxter, Joe / Atwan, Nadeem

    Cureus

    2023  Volume 15, Issue 6, Page(s) e39921

    Abstract: Background and objective Due in part to its effect on intraocular pressure (IOP) measurements, the assessment of central corneal thickness (CCT) is recognized as an essential part of the initial glaucoma assessment. The most widely utilized clinical ... ...

    Abstract Background and objective Due in part to its effect on intraocular pressure (IOP) measurements, the assessment of central corneal thickness (CCT) is recognized as an essential part of the initial glaucoma assessment. The most widely utilized clinical technique to measure CCT is ultrasound pachymetry (USP). In recent years, many dedicated anterior-segment optical coherence tomography scanners (AS-OCTs) have been developed. Previous studies have compared CCT measurements between USP and various AS-OCTs. This study aimed to assess the degree of agreement between USP and CASIA2 (Tomey Corporation, Nagoya, Japan), a second-generation swept-source AS-OCT developed in Japan. Methodology The data on CCT screening measurements of 156 eyes (88 patients) performed over a period of three months, from January to March 2020, on glaucoma patients attending the Royal Hallamshire Hospital (RHH) in Sheffield, UK were collected retrospectively and statistically analyzed. Results The average age of the 88 patients included in the study was 66 years (range: 20-86 years). Our findings show that when compared to CASIA2 measurements, USP measurement of the CCT resulted in significantly thicker values (paired t-test: t=23.15,p<2.2 x 10
    Language English
    Publishing date 2023-06-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.39921
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  7. Article ; Online: Inverse design of optical pulse shapes for time-varying photonics.

    Baxter, Joshua / Ramunno, Lora

    Optics express

    2023  Volume 31, Issue 14, Page(s) 22671–22684

    Abstract: Recent advancements in materials and metamaterials with strong, time-varying, nonlinear optical responses have spurred a surge of interest in time-varying photonics. This opens the door to novel optical phenomena including reciprocity breaking, frequency ...

    Abstract Recent advancements in materials and metamaterials with strong, time-varying, nonlinear optical responses have spurred a surge of interest in time-varying photonics. This opens the door to novel optical phenomena including reciprocity breaking, frequency translation, and amplification that can be further optimized by improving the light-matter interaction. Although there has been recent interest in applying topology-based inverse design to this problem, we propose a novel approach in this article. We introduce a method for the inverse design of optical pulse shapes to enhance their interaction with time-varying media. We validate our objective-first approach by maximizing the transmittance of optical pulses of equal intensity through time-varying media. Through this approach, we achieve large, broadband enhancements in pulse energy transmission, including gain, without altering the incident pulse energy. As a final test, we maximize pulse transmission through thin films of indium tin oxide, a time-varying medium when strongly pumped in its ENZ band. Our work presents a new degree of freedom for the exploration, application, and design of time-varying systems and we hope it inspires further research in this direction.
    Language English
    Publishing date 2023-07-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1491859-6
    ISSN 1094-4087 ; 1094-4087
    ISSN (online) 1094-4087
    ISSN 1094-4087
    DOI 10.1364/OE.485902
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: "A Rising Tide Raises All Boats?"

    Blanchard, Lisa / Baxter, Jeffrey

    Medical care

    2023  Volume 61, Issue 12, Page(s) 813–815

    Language English
    Publishing date 2023-10-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 411646-x
    ISSN 1537-1948 ; 0025-7079
    ISSN (online) 1537-1948
    ISSN 0025-7079
    DOI 10.1097/MLR.0000000000001940
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 518: Show issues Location:
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  9. Article ; Online: CVID With Unusual Peripheral Mononeuropathy and Associated IL-7 Receptor Mutation.

    Baxter, Joseph / Waters, Aubri

    Military medicine

    2023  

    Abstract: Common variable immunodeficiency (CVID) is the most common symptomatic primary immunodeficiency. It is characterized by hypogammaglobulinemia and can present with a broad range of symptoms including recurrent bacterial infections, autoimmunity, and ... ...

    Abstract Common variable immunodeficiency (CVID) is the most common symptomatic primary immunodeficiency. It is characterized by hypogammaglobulinemia and can present with a broad range of symptoms including recurrent bacterial infections, autoimmunity, and malignancy. Rarely, it has been implicated with peripheral neuropathy. We present a case of CVID with peripheral neuropathy and a pathogenic heterozygous variant of IL-7 receptor gene. The patient is a 38-year-old female with a history of recurrent infections since childhood including pneumonia and sinus infections status post tonsillectomy and sinus surgery. She subsequently developed severe left leg and lower back pain that progressed to left foot drop and decreased sensation over the left leg. She was found to have severe hypogammaglobulinemia and poor polysaccharide and protein response, thus meeting criteria for CVID. Mononeuropathy is a rare finding in CVID. Genetic panel was performed and was significant for a single pathogenic variant in IL-7 receptor. Disruptions in the IL-7 and IL-7 receptor signaling pathway have been associated with autoimmunity such as rheumatoid arthritis and multiple sclerosis. Further investigation is indicated to determine the clinical significance of this variant.
    Language English
    Publishing date 2023-12-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 391061-1
    ISSN 1930-613X ; 0026-4075
    ISSN (online) 1930-613X
    ISSN 0026-4075
    DOI 10.1093/milmed/usad480
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  10. Article: Focused ultrasounds: What is their future in epileptology? A critical review.

    Maliia, M D / Nica, A / Baxter, J / Corniola, M V

    Revue neurologique

    2023  Volume 180, Issue 4, Page(s) 348–353

    Abstract: High intensity focused ultrasounds (HIFU) are being increasingly advocated as a useful tool in the management of focal drug-resistant epilepsy. Our aim was to review current literature on the topic and perform an inventory of open trials assessing HIFU ... ...

    Abstract High intensity focused ultrasounds (HIFU) are being increasingly advocated as a useful tool in the management of focal drug-resistant epilepsy. Our aim was to review current literature on the topic and perform an inventory of open trials assessing HIFU effectiveness and safety in epilepsy management. To do so, a review was conducted and yielded one prospective clinical trials, two case reports and one safety study were retrieved, indicating that HIFU is still in its infancy when it comes to focal drug-resistant epilepsy therapy. Efforts should be made to develop this technology using multicentric prospective data with larger cohorts and prolonged follow-up.
    MeSH term(s) Humans ; Epilepsy/therapy ; High-Intensity Focused Ultrasound Ablation/methods ; High-Intensity Focused Ultrasound Ablation/trends ; Drug Resistant Epilepsy/therapy ; Treatment Outcome ; Forecasting
    Language English
    Publishing date 2023-12-12
    Publishing country France
    Document type Journal Article ; Review
    ZDB-ID 4593-7
    ISSN 2213-0004 ; 0035-3787
    ISSN (online) 2213-0004
    ISSN 0035-3787
    DOI 10.1016/j.neurol.2023.10.014
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