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  1. Article ; Online: Impact of therapeutic education on the choice of renal replacement therapy. Moroccan monocentric experience

    Abouzid, Zineb / Sebti, Kaoutar / Ouzeddoun, Naima / Bayahia, Rabia / Benamar, Loubna

    Nephrologie & therapeutique

    2023  Volume 19, Issue 7, Page(s) 555–567

    Abstract: Introduction: Therapeutic patient education (TPE) is gaining importance in the management of patients with chronic kidney disease (CKD). The objective of this study is to assess the interest of TPE in the acquisition of knowledge concerning CKD and ... ...

    Title translation Impact de l’éducation thérapeutique sur le choix du traitement de suppléance. Expérience monocentrique marocaine
    Abstract Introduction: Therapeutic patient education (TPE) is gaining importance in the management of patients with chronic kidney disease (CKD). The objective of this study is to assess the interest of TPE in the acquisition of knowledge concerning CKD and renal replacement therapy, as well as the orientation of the patients towards a personalized choice of treatment.
    Materials and methods: Patients with a minimum stage 4 CKD were prospectively included between November 2016 and February 2020. We proposed TPE sessions on CKD and its treatment to all patients. We explained the theoretical part through a slideshow about the definition of end-stage renal disease, its symptoms and the various methods of renal replacement therapy. A “basket” of essential material to illustrate a session of hemodialysis (HD) or peritoneal dialysis (PD) was used to achieve the practical part of the study. Data was collected using two questionnaires: the first one, at the start of the session, included the socio-demographic and clinical characteristics of the patients and evaluated their level of basic knowledge, and the second one, at the end of the session, assessed the evolution of knowledge after TPE, leading to a therapeutic choice.
    Results: The mean age of the 211 included patients was 55.59 years old (SD = 15.47). Male to female ratio was 0.73. The level of education was low in 69% of the cases of whom 23.7% were employees. The glomerular filtration rate (GFR) was between 15 and 30 mL/min in 56.8% of the cases. Initial nephropathy was known in 60% of patients while the stage of CKD was unknown in 66.4%. Before TPE, patients with a good level of overall knowledge were around 29%, rising to 73% after TPE. A significant correlation was found between the level of education of the patients and their knowledge score before and after TPE. The choice of renal replacement therapy was taken for PD, TR and HD respectively in 36%, 19% and 11.8% of the cases, while 33.2% asked for time to think. Elderly and/or low educated patients most often remained undecided; moreover those who are young and/or educated prefer TR. During the follow-up period, 46% of patients started renal replacement therapy (36.5% started HD, 8.1% PD and 1.4% KT). The choice made by our patients was respected in 42% of the cases: in all the patients who chose HD; in 36% of those who chose PD, and 19% of those who chose kidney transplantation (KT). The final therapeutic modality was strongly linked to the following parameters: age, GFR and level of education.
    Conclusion: This study highlighted the insufficient level of patients’ information about CKD and its treatment and allowed the patients to express their choice of their replacement therapy, which is a complicated process that must ­integrate the opinion of the nephrologist and the patient’s preference to lead to an ­optimal organization of the therapeutic modality.
    MeSH term(s) Humans ; Male ; Female ; Aged ; Middle Aged ; Renal Replacement Therapy ; Renal Dialysis/methods ; Kidney Failure, Chronic/therapy ; Renal Insufficiency, Chronic ; Educational Status
    Language French
    Publishing date 2023-12-07
    Publishing country France
    Document type English Abstract ; Journal Article
    ZDB-ID 2229575-6
    ISSN 1872-9177 ; 1769-7255
    ISSN (online) 1872-9177
    ISSN 1769-7255
    DOI 10.1684/ndt.2023.50
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Pregnancy after kidney transplantation: Ibn Sina Rabat University hospital experience

    Driouch, Latifa / Azzouzi, Asmaa / Ouzeddoun, Naima / Benamar, Loubna / Bayahia, Rabia / Bouattar, Tarik

    Nephrologie & therapeutique

    2023  Volume 19, Issue 2, Page(s) 109–120

    Abstract: Introduction: Kidney transplantation (KT) restores the fertility of women with end-stage kidney disease (ESKD), thus offering them the possibility of having children. However, pregnancy after kidney transplantation is associated with high maternal-fetal ...

    Title translation Grossesse après transplantation rénale : expérience du service de transplantation rénale du CHU Ibn Sina de Rabat (Maroc)
    Abstract Introduction: Kidney transplantation (KT) restores the fertility of women with end-stage kidney disease (ESKD), thus offering them the possibility of having children. However, pregnancy after kidney transplantation is associated with high maternal-fetal morbidity. The purpose of this work is to report the experience of our service in pregnancies in kidney transplant recipients.
    Materials and methods: We retrospectively studied the records of transplant recipients who had one or more pregnancies after KT. We analyzed clinical (blood pressure, weight gain, oedema, duration of pregnancy, obstetric complication) and biological (creatinine, urinary albumin excretion) parameters.
    Results: Between 1998 and 2020, twenty-one pregnancies occurred in 12 transplant recipients. The average age of patients at the time of conception was 29 ± 5 years with a delay between KT and pregnancy of 43 ± 29 months. Seven pregnancies began with arterial hypertension (HTA) controlled under treatment, proteinuria before conception was negative in all pregnancies and renal function was normal with an average creatinine level of 10.1 ± 1,27 mg/L. Prior to pregnancy, immunosuppression regimens were based on anticalcineurin (n = 21) combined either with mycophenolate mofetil (MMF) (n = 10) or azathioprine (n = 8) or alone (n = 3). Immunosuppression regimens were all associated with corticosteroid therapy. Three months before conception, MMF was relayed by azathioprine in seven pregnancies, on the other hand three other unplanned pregnancies, started under MMF. During pregnancy, the appearance of proteinuria greater than 0,5 g/24 h was noted in three pregnancies in the third trimester. Pregnancy hypertension was found in three pregnancies, one of which progressed to pre-eclampsia. As for renal function, it remained stable with an average creatinine level of 10,3 mg/l in the 3rd trimester. Two cases of acute pyelonephritis were noted. No episode of acute rejection was noted during and 3 months after pregnancy. The delivery was performed by caesarean section in 44.4 %, after an average term of 37 week of amenorrhea ± 2.04 with three cases of prematurity. The average birth weight was 3 110 g ± 450 g. There was one case of spontaneous abortion and two cases of fetal death in utero. After post--partum, renal function remained stable in five patients. In six cases, there was impaired renal function either by acute rejection or secondary to chronic allograft nephropathy.
    Conclusion: In our department, a quarter of transplant recipients were able to carry a pregnancy with a rate of 89 % of successful pregnancies. Pregnancy after KT requires special planning and monitoring. A multidisciplinary collaboration between transplant nephrologist, gynecologist and pediatrician is necessary by referring to the recommendations.
    MeSH term(s) Child ; Pregnancy ; Humans ; Female ; Child, Preschool ; Kidney Transplantation/adverse effects ; Pregnancy Outcome ; Retrospective Studies ; Azathioprine ; Cesarean Section/adverse effects ; Creatinine ; Pregnancy Complications/etiology ; Mycophenolic Acid/therapeutic use ; Pre-Eclampsia/drug therapy ; Hypertension/complications ; Hospitals ; Immunosuppressive Agents/adverse effects ; Graft Rejection
    Chemical Substances Azathioprine (MRK240IY2L) ; Creatinine (AYI8EX34EU) ; Mycophenolic Acid (HU9DX48N0T) ; Immunosuppressive Agents
    Language French
    Publishing date 2023-03-14
    Publishing country France
    Document type English Abstract ; Journal Article
    ZDB-ID 2229575-6
    ISSN 1872-9177 ; 1769-7255
    ISSN (online) 1872-9177
    ISSN 1769-7255
    DOI 10.1684/ndt.2023.2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Pregnancy after kidney transplantation: Ibn Sina Rabat University hospital experience

    Driouch, Latifa / Azzouzi, Asmaa / Ouzeddoun, Naima / Benamar, Loubna / Bayahia, Rabia / Bouattar, Tarik

    Nephrologie & therapeutique

    2023  Volume 19, Issue 1, Page(s) 1–11

    Abstract: Introduction: Kidney transplantation (KT) restores the fertility of women with end-stage kidney disease (ESKD), thus offering them the possibility of having children. However, pregnancy after kidney transplantation is associated with high maternal-fetal ...

    Title translation Grossesse après transplantation rénale : expérience du service de transplantation rénale du CHU Ibn Sina de Rabat (Maroc)
    Abstract Introduction: Kidney transplantation (KT) restores the fertility of women with end-stage kidney disease (ESKD), thus offering them the possibility of having children. However, pregnancy after kidney transplantation is associated with high maternal-fetal morbidity. The purpose of this work is to report the experience of our service in pregnancies in kidney transplant recipients.
    Materials and methods: We retrospectively studied the records of transplant recipients who had one or more pregnancies after KT. We analyzed clinical (blood pressure, weight gain, oedema, duration of pregnancy, obstetric complication) and biological (creatinine, urinary albumin excretion) parameters.
    Results: Between 1998 and 2020, twenty-one pregnancies occurred in 12 transplant recipients. The average age of patients at the time of conception was 29 ± 5 years with a delay between KT and pregnancy of 43 ± 29 months. Seven pregnancies began with arterial hypertension (HTA) controlled under treatment, proteinuria before conception was negative in all pregnancies and renal function was normal with an average creatinine level of 10.1 ± 1,27 mg/L. Prior to pregnancy, immunosuppression regimens were based on anticalcineurin (n = 21) combined either with mycophenolate mofetil (MMF) (n = 10) or azathioprine (n = 8) or alone (n = 3). Immunosuppression regimens were all associated with corticosteroid therapy. Three months before conception, MMF was relayed by azathioprine in seven pregnancies, on the other hand three other unplanned pregnancies, started under MMF. During pregnancy, the appearance of proteinuria greater than 0,5 g/24 h was noted in three pregnancies in the third trimester. Pregnancy hypertension was found in three pregnancies, one of which progressed to pre-eclampsia. As for renal function, it remained stable with an average creatinine level of 10,3 mg/l in the 3rd trimester. Two cases of acute pyelonephritis were noted. No episode of acute rejection was noted during and 3 months after pregnancy. The delivery was performed by caesarean section in 44.4 %, after an average term of 37 week of amenorrhea ± 2.04 with three cases of prematurity. The average birth weight was 3 110 g ± 450 g. There was one case of spontaneous abortion and two cases of fetal death in utero. After post-partum, renal function remained stable in five patients. In six cases, there was impaired renal function either by acute rejection or secondary to chronic allograft nephropathy.
    Conclusion: In our department, a quarter of transplant recipients were able to carry a pregnancy with a rate of 89 % of successful pregnancies. Pregnancy after KT requires special planning and monitoring. A multidisciplinary collaboration between transplant nephrologist, gynecologist and pediatrician is necessary by referring to the recommendations.
    MeSH term(s) Child ; Pregnancy ; Humans ; Female ; Child, Preschool ; Kidney Transplantation/adverse effects ; Pregnancy Outcome ; Retrospective Studies ; Azathioprine ; Cesarean Section/adverse effects ; Creatinine ; Pregnancy Complications/etiology ; Mycophenolic Acid/therapeutic use ; Pre-Eclampsia/drug therapy ; Hypertension/complications ; Hospitals ; Immunosuppressive Agents/adverse effects ; Graft Rejection
    Chemical Substances Azathioprine (MRK240IY2L) ; Creatinine (AYI8EX34EU) ; Mycophenolic Acid (HU9DX48N0T) ; Immunosuppressive Agents
    Language French
    Publishing date 2023-03-06
    Publishing country France
    Document type English Abstract ; Journal Article
    ZDB-ID 2229575-6
    ISSN 1872-9177 ; 1769-7255
    ISSN (online) 1872-9177
    ISSN 1769-7255
    DOI 10.1684/ndt.2023.2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: La thymoglobuline en traitement d’induction chez les transplantés rénaux à faible risque immunologique: une expérience marocaine.

    Abouzid, Zineb / Amar, Mohamed Anass / Abdessater, Maher / Alioubane, Meryem / Benjaafar, Anissa / Ouzeddoun, Naima / Benamar, Loubna / Bayahia, Rabia / Bouattar, Tarik

    The Pan African medical journal

    2022  Volume 41, Page(s) 138

    Abstract: Introduction: Thymoglobulin® is a polyclonal antibody indicated for induction treatment in kidney transplantation. The purpose of this study is to estimate the effectiveness of Thymoglobulin® as induction treatment in kidney transplant patients with low ...

    Title translation Thymoglobulin as induction treatment in kidney transplantants with low immunological risk: a Moroccan experience.
    Abstract Introduction: Thymoglobulin® is a polyclonal antibody indicated for induction treatment in kidney transplantation. The purpose of this study is to estimate the effectiveness of Thymoglobulin® as induction treatment in kidney transplant patients with low immune risk.
    Methods: we conducted a retrospective study between January 2012 and September 2017. Patients with low immunological risk, defined as the absence of previous transplantation and donor-specific antibodies (DSA), were included and received Thymoglobulin® induction therapy. Demographic and clinical characteristics, biological parameters and post-renal transplant complications were studied.
    Results: we enrolled 55 kidney transplant patients with an average follow-up period of 38 ± 16 months. The average age of patients was 39,1 ± 12,1 years with a male predominance (58.2%). No patient had DSA prior to transplant. Cumulative dose of Thymoglobulin® was 4,26 ± 0,87 mg/kg, with an average duration of 5 ± 0,82 days. Lymphocyte depletion was maximal on the first day of infusion. Three patients had delayed graft function, at least one episode of bacterial infection in 56,4% of patients, 7 cases of CMV infections (12,7%) and 2 cases of CMV disease (3,6%). Graft survival rate was calculated for all patients with an average serum creatinine of 11,7 ± 3,6 mg/l during the last visit.
    Conclusion: although it is not indicated for first line treatment in patients with low immunological risk, Thymoglobulin® can nevertheless be prescribed at a lower dose, with similar efficacy and without exposure to a higher risk of rejection.
    MeSH term(s) Antilymphocyte Serum ; Cytomegalovirus Infections/drug therapy ; Female ; Graft Rejection/prevention & control ; Graft Survival ; Humans ; Immunosuppressive Agents/therapeutic use ; Infant, Newborn ; Kidney ; Male ; Retrospective Studies
    Chemical Substances Antilymphocyte Serum ; Immunosuppressive Agents ; thymoglobulin (D7RD81HE4W)
    Language French
    Publishing date 2022-02-17
    Publishing country Uganda
    Document type Journal Article
    ZDB-ID 2514347-5
    ISSN 1937-8688 ; 1937-8688
    ISSN (online) 1937-8688
    ISSN 1937-8688
    DOI 10.11604/pamj.2022.41.138.23091
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Amylose AA vésicale : une localisation rare. À propos d’un cas.

    Hikki, Nisrine / Sassi, Samia / Reguieg, Naji / Znati, Kaoutar / Bouattar, Tarik / Benamar, Loubna / Bayahia, Rabia / Ouzeddoun, Naima

    Nephrologie & therapeutique

    2022  Volume 18, Issue 7, Page(s) 655–657

    Abstract: Introduction: Bladder localization of AA amyloidosis is rare. It can be responsible for massive and recurrent hematuria. We report a case of bladder AA amyloidosis secondary to Crohn's disease in a renal transplant patient.: Clinical observation: A ... ...

    Title translation Bladder AA amyloidosis: A rare location. About a case.
    Abstract Introduction: Bladder localization of AA amyloidosis is rare. It can be responsible for massive and recurrent hematuria. We report a case of bladder AA amyloidosis secondary to Crohn's disease in a renal transplant patient.
    Clinical observation: A 62-year-old man, suffering from Crohn's disease since 1991 complicated by renal AA amyloidosis. He received a kidney transplant since 20 years from an HLA identical donor. After an 18-year period of clinical remission, the patient was admitted for a flare-up of his Crohn's disease in the form of intermittent diarrhoea. Treatment with corticosteroids allowed a good evolution. A year later, he was rehospitalized for massive macroscopic haematuria. Histological examination of the bladder biopsy revealed AA amyloidosis. The patient fully recovered but died 6 weeks later from septic shock of urinary origin.
    Conclusion: The treatment of bladder localization of AA amyloidosis is based on treating the cause. Hematuria is sometimes massive, exceptionally requiring emergency cystectomy for haemostasis.
    Language French
    Publishing date 2022-11-22
    Publishing country France
    Document type English Abstract ; Journal Article
    ZDB-ID 2229575-6
    ISSN 1872-9177 ; 1769-7255
    ISSN (online) 1872-9177
    ISSN 1769-7255
    DOI 10.1016/j.nephro.2022.10.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Polyangéite microscopique induite par un inhibiteur de la recapture de la sérotonine. À propos d’un cas.

    Sebti, Kaoutar / Benjaafar, Anissa / Bouattar, Tarik / Abouzid, Zineb / Chattahi, Manal / Rouass, Lamia / Benamar, Loubna / Bayahia, Rabia / Ouzeddoun, Naima

    Nephrologie & therapeutique

    2021  Volume 18, Issue 1, Page(s) 66–69

    Abstract: Microscopic polyangiitis is an ANCA-associated vasculitis and affects small sized vessels. We report a case of microscopic polyangiitis, in a 31 year old patient with renal, skin and neurologic manifestations, which was probably triggered by a selective ... ...

    Title translation Microscopic polyangiitis induced by a serotonin reuptake inhibitor. Case report.
    Abstract Microscopic polyangiitis is an ANCA-associated vasculitis and affects small sized vessels. We report a case of microscopic polyangiitis, in a 31 year old patient with renal, skin and neurologic manifestations, which was probably triggered by a selective serotonin reuptake inhibitor. Under induction therapy with corticosteroids and cyclophosphamide, the kidney recovery is complete, neurological is slow but satisfactory.
    MeSH term(s) Adult ; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis ; Antibodies, Antineutrophil Cytoplasmic ; Cyclophosphamide ; Humans ; Kidney ; Microscopic Polyangiitis/diagnosis ; Microscopic Polyangiitis/drug therapy ; Serotonin Uptake Inhibitors/adverse effects
    Chemical Substances Antibodies, Antineutrophil Cytoplasmic ; Serotonin Uptake Inhibitors ; Cyclophosphamide (8N3DW7272P)
    Language French
    Publishing date 2021-06-02
    Publishing country France
    Document type Case Reports ; Journal Article
    ZDB-ID 2229575-6
    ISSN 1872-9177 ; 1769-7255
    ISSN (online) 1872-9177
    ISSN 1769-7255
    DOI 10.1016/j.nephro.2021.03.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: HLA-identical living related kidney transplantation: Outcomes of a national multicenter study.

    Bentata, Yassamine / ElKabbaj, Driss / Bahadi, Abdelaali / Rhou, Hakima / Laouad, Inass / Sqalli, Tarik / Bouattar, Tarik / Ouzeddoun, Naima / Bayahia, Rabia / Ramdani, Benyouns

    International journal of urology : official journal of the Japanese Urological Association

    2022  Volume 29, Issue 6, Page(s) 519–524

    Abstract: Objectives: The kidney prognosis of HLA-identical seems theoretically very interesting with the lowest risk of acute rejection after that of identical twins. Objectives were to determine the prevalence of acute rejection and various complications in a ... ...

    Abstract Objectives: The kidney prognosis of HLA-identical seems theoretically very interesting with the lowest risk of acute rejection after that of identical twins. Objectives were to determine the prevalence of acute rejection and various complications in a cohort of HLA-identical living-related kidney transplant.
    Methods: A retrospective, multicenter study was conducted in seven university centers in Morocco, which included all recipients of an HLA-identical living-related kidney transplant performed between 1990 and 2019.
    Results: Data on 68 HLA-identical living-related kidney transplants were collected. The donors were siblings in 89.7%, the parents in 7.3%, and identical twins in 3% of cases. 53.6% of all recipients were under 35 years old, and 59.4% of them were male. 39.7% of all donors were under 35 years old, and 47% of them were male. 48.5% of HLA-identical living-related kidney transplants were performed before the year 2000. 18 kidney transplant biopsies were performed on 16 kidney transplant recipients. Seven episodes of acute rejection occurred in six patients, 8.8% of the whole cohort (n = 68). Two cases of acute rejection among the seven were related to poor adherence, cessation of immunosuppressive therapy, and loss of medical follow-up by these patients. These two patients were 20 years old at the time of kidney transplantation. The global kidney transplant survival was 66.7% versus 91.9% (P = 0.04) in the two patient groups having developed acute rejection and not having developed acute rejection, respectively.
    Conclusions: Acute rejection is a real threat to HLA-identical kidney transplant recipients. Therefore, it seems very important to codify the immunosuppressive regimen and to adopt a minimal and effective treatment.
    MeSH term(s) Adult ; Female ; Graft Rejection/epidemiology ; Graft Survival ; HLA Antigens ; Humans ; Kidney Transplantation/adverse effects ; Living Donors ; Male ; Registries ; Retrospective Studies ; Young Adult
    Chemical Substances HLA Antigens
    Language English
    Publishing date 2022-02-15
    Publishing country Australia
    Document type Journal Article ; Multicenter Study
    ZDB-ID 1328401-0
    ISSN 1442-2042 ; 0919-8172
    ISSN (online) 1442-2042
    ISSN 0919-8172
    DOI 10.1111/iju.14827
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  8. Article ; Online: Analyse du risque infectieux autour du patient dans l’unité d’hémodialyse de l’hôpital Ibn Sina de Rabat par application de la méthode d’analyse des modes de défaillance, de leurs effets et de leur criticité.

    El Marnissi, Safaa / Khomsi, Zoubida / Kassy Raymond Sylvestre, Allou / El Harti, Jaouad / Taoufik, Jamal / Chaibi, Aicha / Benamar, Loubna / Bayahia, Rabia

    Nephrologie & therapeutique

    2020  Volume 16, Issue 2, Page(s) 105–117

    Abstract: Introduction: Hemodialysis is a technique of extra-renal purification associated with high level of risk. The objective is to assess infectious risk during a hemodialysis session on hygiene around the patient in hospital.: Methods: An a priori risk ... ...

    Title translation Analysis of the infectious risk around the patient in the hemodialysis unit of Ibn Sina Rabat hospital using the failure modes, effects and criticality analysis method.
    Abstract Introduction: Hemodialysis is a technique of extra-renal purification associated with high level of risk. The objective is to assess infectious risk during a hemodialysis session on hygiene around the patient in hospital.
    Methods: An a priori risk assessment by Failure Modes, Effects and Criticality Analysis method (FMECA) was carried out from May to August 2018, in order to overview infectious risk during the process of hemodialysis in the Ibn Sina Hospital (Rabat, Morocco).
    Results: Twenty eight failure modes were identified during the hemodialysis process around the patient: fourteen criticality level 1, ten level 2, and four level 3. A prevention plan has been drafted. Three of the four level 3 failure modes were reduced to level 1 and one to level 2.
    Discussion: FMECA have enabled us to identify the potential risks, to reconsider certain procedures and to suggest measure matrix for the coverage of the most critical risks.
    Conclusion: This analysis makes it possible, through periodic evaluations, to enter a real quality approach, which reinforces the satisfaction of the patients as well as all the actors of the hemodialysis center.
    MeSH term(s) Cross Infection/epidemiology ; Cross Infection/etiology ; Cross Infection/prevention & control ; Cross-Sectional Studies ; Hemodialysis Units, Hospital ; Hospitals ; Humans ; Kidney Failure, Chronic/therapy ; Morocco ; Renal Dialysis ; Risk Assessment
    Language French
    Publishing date 2020-03-16
    Publishing country France
    Document type Journal Article
    ZDB-ID 2229575-6
    ISSN 1872-9177 ; 1769-7255
    ISSN (online) 1872-9177
    ISSN 1769-7255
    DOI 10.1016/j.nephro.2019.09.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Comparison of the Effects of Dialysis Methods (Haemodialysis vs Peritoneal Dialysis) on Diastolic Left Ventricular Function Dialysis Methods and Diastolic Function.

    Ellouali, Fedoua / Berkchi, Fatimazahra / Bayahia, Rabia / Benamar, Loubna / Cherti, Mohammed

    The open cardiovascular medicine journal

    2016  Volume 10, Page(s) 171–178

    Abstract: Introduction: In patients undergoing chronic dialysis, several factors appear to influence the occurrence of cardiac abnormalities. The aim of our study was to evaluate the effects of two different methods of renal replacement therapy (chronic ... ...

    Abstract Introduction: In patients undergoing chronic dialysis, several factors appear to influence the occurrence of cardiac abnormalities. The aim of our study was to evaluate the effects of two different methods of renal replacement therapy (chronic haemodialysis (HD) and continuous ambulatory peritoneal dialysis (CAPD)) on left ventricular (LV) diastolic function.
    Patients and methods: We enrolled 63 patients: 21 patients on CAPD, and 42 age- and gender-matched patients on HD; 35 patients were men (55.6%). Median of age was 46.4 (35-57) years. The median duration of renal replacement therapy was 3(2-5) years.
    Results: The two groups (HD vs PD) were similar concerning body mass index, dialysis duration and cardiovascular risk factors. The comparison of echocardiographic parameters showed statistically significant differences between two groups, regarding the presence of calcification, cardiac effusion, severely abnormal left ventricular hypertrophy(LVH) and the ratio of mitral velocity to early diastolic velocity of the mitral annulus (E/e') >13 (p= 0.001, p= 0.003, p= 0.02, p= 0.004, respectively). In multivariate analysis, an E/e'>13 was higher in PD group ( OR= 5.8, CI [1.3-25.5], p=0.002).
    Conclusion: The method of dialysis seems to influence LV diastolic function. We observed a higher prevalence of diastolic LV dysfunction in the PD group. Echocardiographic follow up is essential as this could improve the management of cardiovascular complications in dialysis patients.
    Language English
    Publishing date 2016-07-29
    Publishing country United Arab Emirates
    Document type Journal Article
    ZDB-ID 2396047-4
    ISSN 1874-1924
    ISSN 1874-1924
    DOI 10.2174/1874192401610010171
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Mechanical complications of continuous ambulatory peritoneal dialysis: Experience at the Ibn Sina University Hospital.

    Flayou, Kaoutar / Ouzeddoun, Naima / Bayahia, Rabia / Rhou, Hakima / Benamar, Loubna

    Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia

    2016  Volume 27, Issue 1, Page(s) 107–110

    Abstract: Peritoneal dialysis is a new renal replacement therapy recently introduced in Morocco since 2006. Continuous ambulatory peritoneal dialysis has proven to be as effective as hemodialysis. However, it is associated with several complications. The aim of ... ...

    Abstract Peritoneal dialysis is a new renal replacement therapy recently introduced in Morocco since 2006. Continuous ambulatory peritoneal dialysis has proven to be as effective as hemodialysis. However, it is associated with several complications. The aim of this study was to evaluate the outcome of complications in patients treated with peritoneal dialysis at our center. The nature of non-infectious complications was noted during follow-up in these patients. Fiftyseven complications were noted among 34 patients between June 2006 and June 2014. Catheter migration was the most common complication (36.8%), followed by obstruction (14%), dialysate leaks (14%), hemorrhagic complications (10.5%) and, finally, hernia (12.2%), catheter perforation (5.2%) and externalization (3.5%).
    MeSH term(s) Catheters, Indwelling/adverse effects ; Extravasation of Diagnostic and Therapeutic Materials/epidemiology ; Extravasation of Diagnostic and Therapeutic Materials/etiology ; Female ; Follow-Up Studies ; Hospitals, University ; Humans ; Incidence ; Kidney Failure, Chronic/therapy ; Male ; Middle Aged ; Morocco/epidemiology ; Peritoneal Dialysis, Continuous Ambulatory/adverse effects ; Risk Assessment ; Risk Factors ; Treatment Failure
    Language English
    Publishing date 2016-01
    Publishing country Saudi Arabia
    Document type Journal Article ; Observational Study
    ZDB-ID 1379955-1
    ISSN 1319-2442
    ISSN 1319-2442
    DOI 10.4103/1319-2442.174089
    Database MEDical Literature Analysis and Retrieval System OnLINE

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