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  1. Article ; Online: Response to `Rehospitalization indications of children hospitalized for COVID-19 infections and long COVID`.

    Cem, Ela / Özenen, Gizem Güner / Bayram, Nuri / Devrim, İlker

    The Turkish journal of pediatrics

    2024  Volume 66, Issue 1, Page(s) 145–146

    MeSH term(s) Child ; Humans ; Patient Readmission ; Post-Acute COVID-19 Syndrome ; COVID-19 ; Hospitalization ; Risk Factors
    Language English
    Publishing date 2024-03-25
    Publishing country Turkey
    Document type Journal Article
    ZDB-ID 123487-0
    ISSN 2791-6421 ; 0041-4301
    ISSN (online) 2791-6421
    ISSN 0041-4301
    DOI 10.24953/turkjped.2023.800
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    Zs.B 988: Show issues Location:
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  2. Article ; Online: Infection control practices in children during COVID-19 pandemic: Differences from adults.

    Devrim, İlker / Bayram, Nuri

    American journal of infection control

    2020  Volume 48, Issue 8, Page(s) 933–939

    Abstract: Background: Limited studies have been published on practices and management of Coronavirus Disease 2019 (COVID-19) in children. Despite the fact that COVID-19 rarely caused any severe disease in children, the asymptomatic children might be playing an ... ...

    Abstract Background: Limited studies have been published on practices and management of Coronavirus Disease 2019 (COVID-19) in children. Despite the fact that COVID-19 rarely caused any severe disease in children, the asymptomatic children might be playing an important role for spreading COVID-19 in healthcare facilities. This review aimed at sharing our experience of how to handle patients with COVID-19 in a pediatric referral and tertiary care hospital to prevent the possible transmissions to the healthcare workers (HCWs).
    Methods: This review sought to identify infection control practices measures during COVID-19 pandemic comes from our daily practice combined with the most recent guidelines with the new experience and information.
    Results: Prevention the transmission of COVID-19 to the HCWs, 4 primary themes should be taken into consideration; (1) ongoing education and importance of the organization of the healthcare facility, (2) proper clinical triage and isolation of the suspected or confirmed COVID-19 patients in the outpatient clinics and in the emergency departments, (3) necessity of the organization of the COVID-19 wards, and (4) utilization of personal protective equipment.
    Conclusions: Infection control precautions to prevent the possible transmissions to HCWs as well as the other patients and their caregivers from children with COVID-19 are very critical. If sufficient precautions are not taken, healthcare settings may serve as additional source of transmission and spread of COVID-19 in the society.
    MeSH term(s) Adult ; Betacoronavirus/pathogenicity ; COVID-19 ; Child ; Coronavirus Infections/epidemiology ; Coronavirus Infections/prevention & control ; Coronavirus Infections/transmission ; Coronavirus Infections/virology ; Health Personnel ; Humans ; Infection Control/methods ; Infectious Disease Transmission, Patient-to-Professional/prevention & control ; Pandemics/prevention & control ; Personal Protective Equipment/virology ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/transmission ; Pneumonia, Viral/virology ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-26
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 392362-9
    ISSN 1527-3296 ; 0196-6553
    ISSN (online) 1527-3296
    ISSN 0196-6553
    DOI 10.1016/j.ajic.2020.05.022
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    Zs.A 1773: Show issues Location:
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  3. Article ; Online: Response to commentary to "Ultrasonographic evaluation of the children with candiduria for the fungal ball: Is it necessary?"

    Devrim, Fatma / Bayram, Nuri / Devrim, İlker

    Journal of pediatric urology

    2021  Volume 17, Issue 5, Page(s) 740–741

    MeSH term(s) Child ; Foreign Bodies ; Humans ; Urinary Catheterization ; Urinary Tract Infections/diagnostic imaging
    Language English
    Publishing date 2021-08-17
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2237683-5
    ISSN 1873-4898 ; 1477-5131
    ISSN (online) 1873-4898
    ISSN 1477-5131
    DOI 10.1016/j.jpurol.2021.08.010
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    Zs.A 6387: Show issues Location:
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  4. Article: Infection control practices in children during COVID-19 pandemic: Differences from adults

    Devrim, Ilker / Bayram, Nuri

    Am J Infect Control

    Abstract: BACKGROUND: Limited studies have been published on practices and management of Coronavirus Disease 2019 (COVID-19) in children. Despite the fact that COVID-19 rarely caused any severe disease in children, the asymptomatic children might be playing an ... ...

    Abstract BACKGROUND: Limited studies have been published on practices and management of Coronavirus Disease 2019 (COVID-19) in children. Despite the fact that COVID-19 rarely caused any severe disease in children, the asymptomatic children might be playing an important role for spreading COVID-19 in healthcare facilities. This review aimed at sharing our experience of how to handle patients with COVID-19 in a pediatric referral and tertiary care hospital to prevent the possible transmissions to the healthcare workers (HCWs). METHODS: This review sought to identify infection control practices measures during COVID-19 pandemic comes from our daily practice combined with the most recent guidelines with the new experience and information. RESULTS: Prevention the transmission of COVID-19 to the HCWs, 4 primary themes should be taken into consideration; (1) ongoing education and importance of the organization of the healthcare facility, (2) proper clinical triage and isolation of the suspected or confirmed COVID-19 patients in the outpatient clinics and in the emergency departments, (3) necessity of the organization of the COVID-19 wards, and (4) utilization of personal protective equipment. CONCLUSIONS: Infection control precautions to prevent the possible transmissions to HCWs as well as the other patients and their caregivers from children with COVID-19 are very critical. If sufficient precautions are not taken, healthcare settings may serve as additional source of transmission and spread of COVID-19 in the society.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #361384
    Database COVID19

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  5. Article ; Online: Infection control practices in children during COVID-19 pandemic

    Devrim, İlker / Bayram, Nuri

    American Journal of Infection Control

    Differences from adults

    2020  Volume 48, Issue 8, Page(s) 933–939

    Keywords Public Health, Environmental and Occupational Health ; Health Policy ; Epidemiology ; Infectious Diseases ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 392362-9
    ISSN 1527-3296 ; 0196-6553
    ISSN (online) 1527-3296
    ISSN 0196-6553
    DOI 10.1016/j.ajic.2020.05.022
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    Zs.A 1773: Show issues Location:
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  6. Article ; Online: Changes in the incidence of Candida-related central line-associated bloodstream infections in pediatric intensive care unit: Could central line bundle have a role?

    Devrim, İlker / Topal, Sevgi / Ceylan, Gökhan / Oruç, Yeliz / Gülfidan, Gamze / Ayhan, Yüce / Bayram, Nuri / Ağın, Hasan

    Journal de mycologie medicale

    2022  Volume 32, Issue 3, Page(s) 101277

    Abstract: Objective: Candida species are among the most prevalent microorganisms in pediatric critical care units that cause central line-associated bloodstream infections. The goal of this study was to assess the therapeutic benefit of central line bundle for ... ...

    Abstract Objective: Candida species are among the most prevalent microorganisms in pediatric critical care units that cause central line-associated bloodstream infections. The goal of this study was to assess the therapeutic benefit of central line bundle for the prevention of Candida species-related bloodstream infections in pediatric intensive care units.
    Design: The study covered the period from January 1, 2009, to December 31, 2019. Pre-bundle and bundle phases were included in the research. The Clinical Microbiology Laboratory's records revealed episodes of Candida-related central line-associated bloodstream infections.
    Setting: The study was conducted in the Dr. Behçet Uz Child Disease and Pediatric Surgery Training and Research Hospital's PICU (which has 24 beds and admits 350 patients per year).
    Patients: This study included pediatric patients in the pediatric intensive care unit with non-tunneled central venous catheters.
    Interventions: In the pediatric intensive care unit, a central line bundle was started.
    Results: A total of 236 Candida-related central line-associated bloodstream infections were discovered during the study period. Non-albicans Candida accounted for 83.5% (197) of the total, whereas C.albicans accounted for 16.5%(39). During the pre-bundle period, 137 Candida species were isolated from the patients, while 99 Candida species were isolated during the bundle period. Candida-related central line-associated bloodstream infections dropped from 13.68 to 5.93 per 1000 CL-days after the central line bundle was used (p < 0.001).
    Conclusions: According to our findings, the central line bundle greatly reduced central line-associated Candida species bloodstream infections. Central line bundles are an effective scientific solution for preventing Candida-related central line-associated bloodstream infections in hospitals with high Candida prevalence.
    MeSH term(s) Candida ; Catheter-Related Infections/epidemiology ; Catheter-Related Infections/microbiology ; Catheter-Related Infections/prevention & control ; Catheterization, Central Venous/adverse effects ; Central Venous Catheters/adverse effects ; Child ; Cross Infection/epidemiology ; Cross Infection/microbiology ; Cross Infection/prevention & control ; Humans ; Incidence ; Intensive Care Units ; Intensive Care Units, Pediatric ; Sepsis/complications
    Language English
    Publishing date 2022-04-06
    Publishing country France
    Document type Journal Article
    ZDB-ID 1067006-3
    ISSN 1773-0449 ; 1156-5233
    ISSN (online) 1773-0449
    ISSN 1156-5233
    DOI 10.1016/j.mycmed.2022.101277
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    Zs.A 3148: Show issues Location:
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  7. Article ; Online: A rare complication of pulmonary tuberculosis in childhood: Rasmussen`s aneurysm in a 9-year-old child with Down syndrome.

    Böncüoğlu, Elif / Çınar, Celal / Kıymet, Elif / Çağlar, İlknur / Kara, Aybüke Akaslan / Bayram, Nuri / Devrim, İlker

    The Turkish journal of pediatrics

    2022  Volume 64, Issue 2, Page(s) 408–411

    Abstract: Background: As an extremely rare entity reported in children, Rasmussen`s aneurysm is an inflammatory pseudo-aneurysmal dilatation of a branch of the pulmonary artery adjacent to or within a tuberculous cavity.: Case: Here, we reported a 9-year-old ... ...

    Abstract Background: As an extremely rare entity reported in children, Rasmussen`s aneurysm is an inflammatory pseudo-aneurysmal dilatation of a branch of the pulmonary artery adjacent to or within a tuberculous cavity.
    Case: Here, we reported a 9-year-old child with Down syndrome who presented with massive hemoptysis. Endovascular coil embolization was performed for Rasmussen`s aneurysm. During the 2-year follow-up period, she had no further episodes of bleeding.
    Conclusions: In case of the development of massive hemoptysis in the follow-up of a patient with pulmonary tuberculosis and Down syndrome, this lethal complication should be considered.
    MeSH term(s) Aneurysm/complications ; Aneurysm/diagnostic imaging ; Aneurysm/therapy ; Child ; Down Syndrome/complications ; Embolization, Therapeutic ; Female ; Hemoptysis/etiology ; Humans ; Tuberculosis, Pulmonary/complications
    Language English
    Publishing date 2022-05-21
    Publishing country Turkey
    Document type Case Reports
    ZDB-ID 123487-0
    ISSN 2791-6421 ; 0041-4301
    ISSN (online) 2791-6421
    ISSN 0041-4301
    DOI 10.24953/turkjped.2021.1617
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    Zs.B 988: Show issues Location:
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  8. Article: The evaluation of Candida-related central line-related bloodstream infections in pediatric cancer patients: A pre- and post-intervention study.

    Devrim, İlker / Celebi, Miray Yılmaz / Karakaya, Nurgul / Sahinkaya, Sahika / Acar, Sultan Okur / Cem, Ela / Demirağ, Bengü / Oruc, Yeliz / Kara, Aybuke Akaslan / Oymak, Yesim / Karapınar, Tuba Hilkay / Bayram, Nuri

    Journal of infection prevention

    2023  Volume 24, Issue 5, Page(s) 219–222

    Abstract: Aim/objections: The purpose of this study was to assess the efficacy of a central line maintenance bundle in preventing catheter-related (implanted venous access devices, port) Candida bloodstream infections.: Methods: The study encompassed two ... ...

    Abstract Aim/objections: The purpose of this study was to assess the efficacy of a central line maintenance bundle in preventing catheter-related (implanted venous access devices, port) Candida bloodstream infections.
    Methods: The study encompassed two distinct time periods, namely, pre-bundle and bundle. The number of catheter-related bloodstream infections (CRBSI) episodes per catheter days for each timeframe was determined.
    Findings/results: Upon implementation of the central line bundle, the rate of CRBSI reduced significantly from 4.27 per 1000 central line days in the pre-bundle period to 1.0 per 1000 central line days in the bundle period (
    Discussion: Using a central line bundle to avoid CRBSIs in pediatric cancer patients with ports led to a significant decrease in Candida species-related CRBSIs.
    Language English
    Publishing date 2023-08-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2595000-9
    ISSN 1757-1782 ; 1757-1774
    ISSN (online) 1757-1782
    ISSN 1757-1774
    DOI 10.1177/17571774231191334
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  9. Article ; Online: Risk of tuberculosis in children with rheumatologic diseases treated with biological agents: A cross-sectional cohort study.

    Bayram, Nuri / Altuğ Gücenmez, Özge / Makay, Balahan / Kıymet, Elif / Böncüoğlu, Elif / Şahinkaya, Şahika / Sorguç, Yelda / Akaslan Kara, Aybüke / Ötiken Arıkan, Kamile / Devrim, İlker

    Archives of rheumatology

    2023  Volume 38, Issue 4, Page(s) 549–555

    Abstract: Objectives: This study aimed to evaluate the risk of tuberculosis (TB) disease in children receiving biological agents for rheumatologic diseases, focusing on appropriate screening tests in a high-priority country for TB control.: Patients and methods! ...

    Abstract Objectives: This study aimed to evaluate the risk of tuberculosis (TB) disease in children receiving biological agents for rheumatologic diseases, focusing on appropriate screening tests in a high-priority country for TB control.
    Patients and methods: One hundred nine children (56 females, 53 males; range, 3.4 to 16.2 years) who received any biological agent for rheumatologic diseases for more than two years between May 2012 and October 2021 were included in this retrospective study. Patients were screened for TB infection using tuberculin skin test (TST) or interferon-gamma release assay (IGRA). Following the initial evaluation, patients were clinically examined for TB every three months by a comprehensive medical history and physical examination, and every 12 months using TST or IGRA.
    Results: At the initiation of the biological agent, the patients' mean age was 12.4±4.5 years. The average follow-up duration was 3.6±1.3 years (range, 2.6 to 10.2 years) for patients treated with biological agents. Each patient had a documented Bacillus Calmette-Guérin vaccination. Before the initiating of therapy, TST was performed alone in 45 (41.3%) patients and in combination with IGRA in 64 (58.7%) patients. In the 64 patients who underwent both TST and IGRA, IGRA revealed nine (14.1%) positive results. Six (66.7%) of these nine patients, however, had negative baseline TST. Four (7.3%) of the 55 individuals whose initial IGRA results were negative also had positive TST results. Overall, no TB disease was observed after a follow-up period.
    Conclusion: This study reveals that biological agents were not associated with an increased risk of TB disease in closely monitored children. Additionally, the concomitant use of TST and IGRA for screening of TB is reasonable in patients receiving biological agents.
    Language English
    Publishing date 2023-02-03
    Publishing country Turkey
    Document type Journal Article
    ZDB-ID 3012972-2
    ISSN 2618-6500 ; 2148-5046
    ISSN (online) 2618-6500
    ISSN 2148-5046
    DOI 10.46497/ArchRheumatol.2023.9900
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  10. Article ; Online: Rehospitalization indications of children hospitalized for COVID-19 infections after discharge: Should we suspect long COVID?

    Cem, Ela / Kıymet, Elif / Böncüoğlu, Elif / Şahinkaya, Şahika / Çelebi, Miray Yılmaz / Gülderen, Mustafa / Kara, Aybüke Akaslan / Özenen, Gizem Güner / Bayram, Nuri / Devrim, İlker

    The Turkish journal of pediatrics

    2023  Volume 65, Issue 4, Page(s) 583–591

    Abstract: Background: Complications that may develop in children after coronavirus disease 2019 (COVID-19) infections are unknown. The `Long COVID` syndrome is a new process that can also be identified in children. Therefore, in this study, the conditions that ... ...

    Abstract Background: Complications that may develop in children after coronavirus disease 2019 (COVID-19) infections are unknown. The `Long COVID` syndrome is a new process that can also be identified in children. Therefore, in this study, the conditions that may develop in children after COVID-19 infection were discussed, and the indications for rehospitalizations were reviewed.
    Methods: This retrospective cohort study was conducted in a tertiary children`s hospital in İzmir, Türkiye. All children who were rehospitalized in the study center after discharge, and the indications for readmissions were screened.
    Results: Since the beginning of the pandemic, 777 children with COVID-19 infection were hospitalized, including 98 (12.6%) cases rehospitalized for any indication. Fifty-five (56.1%) patients were male, and 43 (43.9%) were female. The mean age of the study population was 79.3±63.5 months (1 month to 17 years). Among these 98 patients, 76 (77.6%) were rehospitalized because of the presence of their primary underlying disease, nonspecific infectious diseases unrelated to COVID-19, and the need to perform certain surgical procedures. The remaining 22 (22.4%) patients presented with symptoms such as fatigue, fever, abdominal pain, and myalgia after the COVID-19 infection. No other underlying cause was detected in approximately one-third of the patients, whose manifestations were found to be consistent with long COVID syndrome.
    Conclusions: The findings of acute COVID-19 infection are well characterized, but there is still limited data on its long-term outcomes. The majority of the study population that had no underlying disease were thought to have complications from the COVID-19 infection. Therefore, although the incidence rate of long COVID syndrome in childhood has not been revealed so far, it should be kept in mind among relevant differential diagnoses.
    MeSH term(s) Humans ; Child ; Female ; Male ; Post-Acute COVID-19 Syndrome ; COVID-19/complications ; Patient Readmission ; Patient Discharge ; Retrospective Studies
    Language English
    Publishing date 2023-09-04
    Publishing country Turkey
    Document type Journal Article
    ZDB-ID 123487-0
    ISSN 2791-6421 ; 0041-4301
    ISSN (online) 2791-6421
    ISSN 0041-4301
    DOI 10.24953/turkjped.2022.829
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